Selective Removal of a Pharmaceutical Process Impurity Using a Reactive Resin

References

• LeVan , M. D. 1996 . Fundamental of Adsorption Edited by: LeVan , M. D. Norwell , MA : Kluwer Academic Publishers .
   Google Scholar
• Rouqueol , F. , Rouquerol , J. and Sing , K. 1999 . Adsorption by Powders and Porous Solids: Principles, Methodology and Applications New York : Academic Press .
   Google Scholar
• Carpino , L. A. , Mansour , E. M.E. , Cheng , C. H. , Williams , J. R. , MacDonald , R. , Knapczyk , J. and Carman , M. 1983 . Polystyrene‐based deblocking‐scavenging agents for the 9‐fluorenylmethyloxycarbonyl amino protecting group . J. Org. Chem. , 48 : 661 – 665 .
   Web of Science ®Google Scholar
• Carpino , L. A. , Manour , E. M.E. and Knapczyk , J. 1983 . Piperazino‐functionalized silica gel as a deblocking‐scavenging agent for the 9‐fluorenylmethyloxycarbonyl amino‐protecting group . J. Org. Chem. , 48 : 666 – 669 .
   Web of Science ®Google Scholar
• Kaldor , S. , Siegel , M. G. , Fritz , J. E. , Dressman , B. A. and Hahn , P. J. 1996 . Use of solid supported nucleophiles and electrophiles for the purification of non‐peptide small molecule libraries . Tet. Lett. , 37 : 7193 – 7196 .
   Web of Science ®Google Scholar
• Flynn , D. L. , Crich , J. Z. , Devraj , R. V. , Hockerman , S. L. , Parlow , J. J. , South , M. S. and Woodard , S. 1997 . Chemical library purification strategies based on principles of complementary molecular reactivity and molecular recognition . J. Amer. Chem. Soc. , 119 : 4874 – 4881 .
   Web of Science ®Google Scholar
• Booth , R. J. and Hodges , J. C. 1997 . Polymer‐supported quenching reagents for parallel purification . J. Amer. Chem. Soc. , 119 : 4882 – 4886 .
   Web of Science ®Google Scholar
• Welch , C. J. , Protopopova , M. N. and Bhat , G. A. 1998 . Microscale synthesis and screening of chiral stationary phases . Enantiomer , 3 : 471 – 476 .
   Google Scholar
• Welch , C. J. , Protopopova , M. N. and Bhat , G. A. 1999 . Selection of an optimized adsorbent for preparative chromatographic enantioseparation by microscale screening of a second‐generation chiral stationary phase library . J. Comb. Chem. , 1 : 364 – 367 .
   PubMedGoogle Scholar
• Welch , C. J. , Protopopova , M. N. and Bhat , G. A. 1999 . “ Microscale synthesis and screening of combinatorial libraries of new chromatographic stationary phases ” . In Fundamental and Applied Aspects of Chemically Modified Surfaces Edited by: Blitz , Little . 129 – 138 . Cambridge , , UK : Royal Society of Chemistry .
   Google Scholar
• Welch , C. J. , Pollard , S. D. , Mathre , D. J. and Reider , P. J. 2001 . Improved method for rapid evaluation of chiral stationary phase libraries . Org. Letters , 3 : 95 – 98 .
   PubMed Web of Science ®Google Scholar
• Welch , C. J. , Protopopova , M. N. and Bhat , G. A. Method for Screening Chromatographic Adsorbents . US Patent #6,342,160 . Jan 29, 2002 .
   Google Scholar
• Welch , C. J. , Shaimi , M. , Biba , M. , Chilenski , J. R. , Szumigala , R. H. , Dolling , U. , Mathre , D. J. and Reider , P. J. 2002 . Microplate evaluation of process adsorbents . J. Sep. Sci. , 25 : 847 – 850 .
   Web of Science ®Google Scholar
• Emerson , S. W. , Emerson , R. R. , Joshi , S. C. , Sorensen , E. M. and Turek , J. E. 1979 . Polymer‐bound sulfonylhydrazine functionality. Preparation, characterization, and reaction of copoly(styrene‐divinylbenzenesulfonylhydrazine) . J. Org. Chem. , 44 : 4634 – 4639 .
   Web of Science ®Google Scholar
• Kamogawa , H. , Kanzawa , A. , Kadoya , M. , Naito , T. and Nanasawa , M. 1983 . Conversions of carbonyl compounds via their polymeric sulfonylhydrazones into alkenes, alkanes and nitriles . Bull. Chem. Soc. Jpn. , 56 : 762 – 765 .
   Web of Science ®Google Scholar
• Galioglu , O. and Akar , A. 1989 . Polymer‐bound sulphonyl hydrazine and reaction with cycloketones . Eur. Polym. J. , 25 : 313 – 316 .
   Web of Science ®Google Scholar