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Original Articles

Mechanistic Studies of the Separation of an HIV Protease Inhibitor from Its Piperazine Diastereomer by Reversed Phase High Performance Liquid Chromatography

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Pages 3343-3355 | Received 08 Jun 2003, Accepted 18 Jul 2003, Published online: 17 Aug 2006

References

  • Tata , J. R. , Chapman , K. T. , Duffy , J. L. , Kevin , N. J. , Cheng , Y. , Rano , T. A. , Zhang , F. , Huening , T. , Kirk , B. A. , Lu , Z. , Raghavan , S. , Fleitz , F. J. , Petrillo , D. E. , Armstrong , J. D. III , Varsolona , R. J. , Askin , D. , Hoerrner , R. S. and Purick , R. Preparation of γ-hydroxy-2-fluoroalkylaminocarbonyl-1-piperazinepentan-amides as HIV protease inhibitors . PCT Int. Appl. , WO 0138332, 2001, Merck Research Labs
  • Tata , J. R. , Charest , M. , Lu , Z. , Raghavan , S. , Huening , T. and Rano , T. Preparation of α-hydroxy-γ-[[(carbocyclic-or heterocyclic-substituted) amino]carbonyl]alkanamides as HIV protease inhibitors . PCT Int. Appl. , WO 0105230, 2001. Merck Research Labs
  • Lochmuller , C. H. , Reese , C. , Aschman , A. J. and Breiner , S. J. 1993 . J. Chromatogr. A , 656 : 3 – 18 .
  • Jaroniec , M. 1993 . J. Chromatogr. A , 656 : 37 – 50 .
  • Tijssen , R. , Schoenmakers , P. J. , Bohmer , M. R. , Koopal , L. K. and Billiet , H. A.H. 1993 . J. Chromatogr. A , 656 : 135 – 196 .
  • Vailaya , A. and Horvath , C. S. 1998 . J. Chromatogr. A , 829 : 1 – 27 .
  • Row , K. H. 1998 . J. Chromatogr. A , 797 : 23 – 31 .
  • Wang , A. , Tan , L. C. and Carr , P. W. 1999 . J. Chromatogr. A , 848 : 21 – 37 .
  • Snyder , L. R. , Dolan , J. W. and Gant , J. R. 1979 . J. Chromatogr. , 165 : 3 – 30 .
  • Ranatunga , R. P.J. and Carr , P. W. 2000 . Anal. Chem. , 72 ( 22 ) : 5679 – 5692 .
  • Snyder , L. R. , Dolan , J. W. and Gant , J. R. 1979 . J. Chromatogr. , 165 : 31 – 58 .
  • Snyder , L. R. 1980 . High Performance Liquid Chromatography—Advances and Perspectives Edited by: Horváth , Cs. Vol. 1 , 207 – 320 . New York : Academic Press .
  • Snyder , L. R. and Stadalius , M. A. 1986 . High Performance Liquid Chromatography—Advances and Perspectives Edited by: Horváth , Cs. Vol. 4 , 193 – 318 . New York : Academic Press .
  • O'Brien , T. , Crocker , L. , Thompson , R. , Thompson , K. , Toma , P. H. , Conlon , D. A. , Feibush , B. , Moeder , C. , Bicker , G. and Grinberg , N. 1997 . Anal.Chem. , 69 ( 11 ) : 1999 – 2007 .
  • Wang , T. , Chen , Y. and Vailaya , A. 2000 . J. Chromatogr. , 902 : 345 – 355 .
  • Treiner , A. , Tzias , P. , Chemla , N. and Poltoratskii , G. M. 1976 . J. Chem. Soc. Faraday Trans.1. , 72 : 2007 – 2015 .
  • Barbosa , J. , Fonrodona , G. , Marqués , I. , Buti , S. and Toro , I. 1997 . Trends in Anal. Chem. , 16 ( 2 ) : 104 – 111 .
  • Marcus , Y. 1988 . J. Chem. Soc. Faraday Trans.1. , 84 ( 5 ) : 1465 – 1473 .
  • Cheong , W. J. and Carr , P. W. 1990 . J. Chromatogr. , 499 : 373 – 393 .
  • Horváth , Cs. , Melander , W. and Molnar , I. 1977 . Anal. Chem. , 49 ( 1 ) : 142 – 154 .
  • Barcella , A. I. , Grunwald , E. , Marshall , H. P. and Purlee , E. L. 1955 . J. Org. Chem. , 20 ( 6 ) : 747 – 762 .
  • Roses , M. , Canals , I. , Allemann , H. , Siigur , K. and Bosch , E. 1996 . Anal. Chem. , 68 ( 23 ) : 4094 – 4100 .
  • LoBrutto , R. , Jones , A. , Kazakevich , Y. V. and McNair , H. M. 2001 . J. Chromatogr. , 913 : 173 – 187 .

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