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Journal of Liquid Chromatography & Related Technologies Volume 26, 2003 - Issue 20
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Original Articles

Development and Validation of an HPTLC‐Densitometry Method for Assay of Caffeine and Acetaminophen in Multicomponent Extra Strength Analgesic Tablets

Caitlin Sullivan Department of Chemistry, Lafayette College, Easton, Pennsylvania, 18042, USA
&
Joseph Sherma Department of Chemistry, Lafayette College, Easton, Pennsylvania, 18042, USACorrespondence[email protected]
Pages 3453-3462 | Received 22 Apr 2003, Accepted 26 Jun 2003, Published online: 17 Aug 2006

References

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  • Ruddy , D. and Sherma , J. 2002 . Analysis of the caffeine in alertness tablets and caplets by high‐performance thin‐layer chromatography with ultraviolet absorption densitometry of fluorescence‐quenched zones . Acta Chromatogr. , 12 : 143 – 150 .
  • Bebawy , L. I. and El‐Kousy , N. M. 1999 . Simultaneous determination of some multicomponent dosage forms by quantitative thin layer chromatography densitometric method . J. Pharm. Biomed. Anal. , 20 ( 4 ) : 663 – 670 .
  • Salem , M. A.S. , Alkaysi , H. N. and Gharaibeh , A. M. 1989 . Quantification of orphenadrine citrate and acetaminophen in tablet formulation using thin‐layer chromatography densitometry . Anal. Lett. , 22 ( 3 ) : 585 – 596 .
  • Salvadori , M. C. , Rieser , E. M. , Ribeiro Neto , L. M. and Nascimento , E. S. 1994 . Determination of xanthines by high‐performance liquid chromatography and thin‐layer chromatography in horse urine after ingestion of guarana powder . Analyst , 119 ( 12 ) : 2701 – 2703 .
  • Kowalska , T. , Kaczmarski , K. and Prus , W. 2003 . “ Theory and mechanism of thin layer chromatography ” . In Handbook of Thin Layer Chromatography , 3rd Ed. Edited by: Sherma , J. and Fried , B. 52 – 55 . New York : Marcel Dekker, Inc. .
  • Ferenczi‐Fodor , K. , Vegh , Z. , Nagy‐Turak , A. , Renger , B. and Zeller , M. 2001 . Validation and quality assurance of planar chromatographic procedures in pharmaceutical analysis . J. AOAC Int. , 84 ( 4 ) : 1265 – 1276 .
  • 2000 . Vol. 22 , United States Pharmacopeia Convention Inc. . The United States Pharmacopeia/The National Formulary (USP24/NF 19)
  • Ramos‐Martos , N. , Aguirre‐Gomez , F. , Molinz‐Diaz , A. and Capitan‐Vallvey , L. F. 2001 . Application of liquid chromatography to the simultaneous determination of acetylsalicylic acid, caffeine, codeine, paracetamol, pyridoxine, and thiamine in pharmaceutical preparations . J.AOAC Int. , 84 ( 3 ) : 676 – 683 .
  • Renger , B. 1998 . Contemporary thin layer chromatography in pharmaceutical quality control . J. AOAC Int. , 81 ( 2 ) : 333 – 339 .

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