CORRELATIONS BETWEEN THE RATE OF INTRACELLULAR RELEASE OF ENDOCYTOSED LIPOSOMAL DOXORUBICIN AND CYTOTOXICITY AS DETERMINED BY A NEW ASSAY

REFERENCES

• Lopes de Menezes D. E., Pilarski L. M., Allen T. M. In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma. Cancer Res. 1998; 58: 3320–3330
   PubMed Web of Science ®Google Scholar
• Lopes de Menezes D. E., Kirchmeier M. J., Gagne J.-F., Pilarski L. M., Allen T. M. Cellular trafficking and cytotoxicity of anti-CD19-targeted liposomal doxorubicin in B lymphoma cells. J. Liposome Res. 1999; 9: 199–228
   Web of Science ®Google Scholar
• Northfelt D. W., Martin F. J., Working P., Volberding P. A., Russell J., Newman M., Amantea M. A., Kaplan L. D. Doxorubicin encapsulated in liposomes containing surface-bound polyethylene glycol: pharmacokinetics tumour localization, and safety in patients with AIDS-related Kaposi's sarcoma. J. Clin. Pharmacol 1996; 36: 55–63
   PubMed Web of Science ®Google Scholar
• Gill P. S., Espina B. M., Muggia F., Cabriales S., Tulpule A., Esplin J. A., Liebman H. A., Forssen E., Ross M. E., Levine A. M. Phase I/II clinical and pharmacokinetic evaluation of liposomal daunorubicin. J. Clin. Oncol. 1995; 13: 996–1003
   PubMed Web of Science ®Google Scholar
• Cowens J. W., Creaven P. J., Greco W. R., Brenner D. E., Tung Y., Osto M., Pilkiewicz F., Ginsberg R., Petrelli N. Initial clinical (phase I) trial of TLC D-99 (doxorubicin encapsulated in liposomes). Cancer Res. 1993; 53: 2796–2802
   PubMed Web of Science ®Google Scholar
• Alava-Moreno G., Valencia-González J., Diaz-Garci M. Room temperature phosphorescence optosensor for anthracyclines. Analyst 1998; 123: 151–154
   Web of Science ®Google Scholar
• Thies R. l., Cowens D. W., Cullis P. R., Bally M. B., Mayer L. D. Method for rapid separation of liposome-associated doxorubicin from free doxorubicin in plasma. Anal Biochem. 1990; 188: 65–71
   PubMed Web of Science ®Google Scholar
• Mayer L. D., Stonge G. Determination of free and liposome associated doxorubicin and vincristine levels in plasma under equilibrium conditions employing ultrafiltration techniques. Analytical Biochem. 1995; 232: 149–157
   PubMed Web of Science ®Google Scholar
• Gigli M., Doglia S. M., Millot J. M., Valentini L., Manfait M. Quantitative study of doxorubicin in living cell nuclei by microspectrofluorometry. Biochim. Biophys. Acta 1988; 950: 13–20
   PubMed Web of Science ®Google Scholar
• Demant E. R., Friche E. Kinetics of anthracycline accumulation in multidrug-resistant tumor cells: Relationship to drug lipophilicity and serum albumin binding. Biochem. Pharmacol. 1998; 56: 1209–1217
   PubMedGoogle Scholar
• Karukstis K. K., Thompson E. H. Z., Whiles J. A., Rosenfeld R. J. Deciphering the fluorescence signature of daunomycin and doxorubicin. Biophys. Chem. 1998; 73: 249–263
   PubMed Web of Science ®Google Scholar
• Chu C. J., Szoka F. C., Jr. pH-sensitive liposomes. J. Liposome Res. 1994; 4: 361–395
   Google Scholar
• Collins D., Norley S., Rouse B., Huang L. Liposomes as carriers for antitumor and antiviral drugs: pH-sensitive immunoliposomes and sustained release immunoliposomes. G. Gregoriadias. John Wiley & Sons Ltd., New York, N.Y. 1988; 761–770, Liposomes as Drug Carriers
   Google Scholar
• Nicol F., Nir S., Szoka F. C., Jr. Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide. Biophys. J. 1996; 71: 3288–3301
   PubMed Web of Science ®Google Scholar
• Bailey A., Monck M. A., Cullis P. R. pH-induced destabilization of lipid bilayers by a lipopeptide derived from influenza hemagglutinin. Biochim. Biophys. Acta 1997; 1324: 232–244
   PubMedGoogle Scholar
• Allen T. M., Hong K., Papahadjopoulos D. Membrane contact, fusion, and hexagonal (HII) transitions in phosphatidylethanolamine liposomes. Biochemistry 1990; 29: 2976–2985
   PubMed Web of Science ®Google Scholar
• Meyer O., Papahadjopoulos D., Leroux J. C. Copolymers of N-isopropylacrylamide can trigger pH sensitivity to stable liposomes. FEBS Lett. 1998; 421: 61–64
   PubMed Web of Science ®Google Scholar
• Kono K., Igawa T., Takagishi T. Cytoplasmic delivery of calcein mediated by liposomes modified with a pH-sensitive poly(ethylene glycol) derivative. Biochim. Biophys. Acta 1997; 1325: 143–154
   PubMed Web of Science ®Google Scholar
• Kirpotin D., Hong K., Mullah N., Papahadjopoulos D., Zalipsky S. Liposomes with detachable polymer coating: destabilization and fusion of dioleoylphosphatidylethanolamine vesicles triggered by cleavage of surface-grafted poly (ethylene glycol). FEBS Lett. 1996; 388: 115–118
   PubMed Web of Science ®Google Scholar
• Allen T. M., Hansen C. B., Martin F., Redemann C., Yau-Young A. Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo. Biochim. Biophys. Acta 1991; 1066: 29–36
   PubMed Web of Science ®Google Scholar
• Pool G. L., French M. E., Edwards R. A., Huang L., Lumb R. H. Use of radiolabelled hexadecyl cholesterol ether as a liposome marker. Lipids 1982; 17: 445–452
   Web of Science ®Google Scholar
• Bolotin E. M., Cohen R., Bar L. K., Emanuel S. N., Lasic D. D., Barenholz Y. Ammonium sulphate gradients for efficient and stable remote loading of amphipathic weak bases into liposomes and ligandosomes. J. Liposome Res. 1994; 4: 455–479
   Google Scholar
• Goren D., Horowitz A. T., Tzemack D., Tarshish M., Zalipsky S., Gabizon A. Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of nultidrug-resistance efflux pump. Clin. Cancer Res. 2000; 6: 1949–1957
   PubMed Web of Science ®Google Scholar
• Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976; 72: 248–254
   PubMed Web of Science ®Google Scholar
• Bogush T., Smirnova G., Shubina I., Syrkin A., Robert J. Direct evaluation of intracellular accumulation of free and polymer-bound anthracyclines. Cancer Chemother. Pharmacol. 1995; 35: 501–505
   PubMedGoogle Scholar
• Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983; 65: 55–63
   PubMed Web of Science ®Google Scholar
• Mahdadi R., Pommery N., Pommery J., Lhermitte M. Quantitative determination of adriamycin in rat hepatocytes using a volatile extraction buffer, HPLC and fluorescence detection. Biomed. Chromatography 1987; 2: 91–94
   PubMedGoogle Scholar
• Kokenberg E., Sonneveld P., Nooter K., van der Steuyt K., Louenberg B. Quantitive evaluation of intracellular uptake of daunorubicin in acute myloid leukemia: a method analysis. Cancer Chemother. Pharmacol 1986; 17: 63–68
   PubMedGoogle Scholar
• Tidefelt U., Sundman-Engberg B., Paul C. Comparison of the intracellular pharmacokinetics of doxorubicin and 4´-ep;i-doxorubicin in patients with acute leukemia. Cancer Chemother. Pharmacol 1989; 24: 225–229
   PubMed Web of Science ®Google Scholar
• Andersen A., Warren D. J., Slørdal L. Quantitation of cell-associated doxorubicin by high-performance liquid chromatography after enzymatic desequestration. Cancer Chemother. Pharmacol 1994; 34: 197–202
   PubMed Web of Science ®Google Scholar
• Ramu A., Pollard H. B., Rosario L. M. Doxorubicin resistance in P388 leukemia–evidence for reduced drug influx. Int. J. Cancer 1989; 44: 539–547
   PubMed Web of Science ®Google Scholar
• Blanchard J. C., Schneider Y. J., Baurain R., Trouet A. Accumulation, metabolism and subcellular localization of daunorubicin, doxorubicin and their DNA-complexes in rat heart ventricles. Eur. J. Cancer 1981; 17: 297–305
   Google Scholar
• Gieseler F., Nübler V., Brieden T., Kunze J., Valsamas S. Intracellular pharmacokinetics and anthracyclines in human leukemia cells: correlation of DNA-binding with apoptotic cell death. Int. J. Clin. Pharmacol. Therap 1998; 36: 25–28
   PubMedGoogle Scholar
• Sambrook J., Fritsch E. F., Maniatis T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, New York 1989
   Google Scholar
• Danjani L. K., Warren D. J., Andersen A., Stromhaug S., Slordal L. Qualitatively different mechanisms of resistance to doxorubicin, both involving altered glutathione pools, in two myeloid cell lines in vitro. Pediatric Hematol. Oncol 1995; 12: 531–544
   PubMedGoogle Scholar