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- *Takagi et al. reported the cleavage of double-stranded DNA by a Cu(II) complex of polyamine-linked DNA-intercalator1 which is an analogous compound of mimic I. We have also ovserved a cleavage of pBR322 DNA by mimic I under the presence of an equal amount of Cu(II) ion. The magnitude of the cleavage was, however, modest to low in our results (data not shown).
- *A recent report of Ushijima et al. describes a site-specific clevage tRNA mediated by β-oligoDNA functionalized at the 5′-terminus with polyamine derivatives26 which are essentially same as mimic I and III described in this article.