Tissue Disposition of 5‐o‐Carboranyluracil—A Novel Agent for the Boron Neutron Capture Therapy of Prostate Cancer

References

• Greenlee , R. T. , Hill‐Harmon , M. B. , Murray , R. , Murray , T. and Thun , M. 2001 . Cancer statistics 2001 . CA Cancer J. Clin. , 51 : 15 – 36 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Barth , R. F. , Soloway , A. H. and Brugger , R. M. 1996 . Boron neutron capture therapy of brain tumors: past history, current status, and future potential . Cancer Investig. , 14 : 534 – 550 . [CSA]
   PubMed Web of Science ®Google Scholar
• Barth , R. F. , Soloway , A. H. , Goodman , J. H. , Gahbauer , R. A. , Gupta , N. , Blue , T. E. , Yang , W. and Tjarks , W. 1999 . Boron neutron capture therapy of brain tumors: an emerging therapeutic modality . Neurosurgery , 44 : 433 – 450 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Flam , F. 1994 . Will history repeat for boron capture therapy? . Science , 265 : 468 – 469 . [PUBMED] [INFOTRIEVE]
   PubMedGoogle Scholar
• Lu , D. R. , Mehta , S. C. and Chen , W. 1997 . Selective boron drug delivery to brain tumors for boron neutron capture therapy . Adv. Drug Deliv. Rev. , 26 : 231 – 247 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Soloway , A. H. , Tjarks , W. , Barnum , B. A. , Rong , F. , Barth , R. F. , Codognic , I. M. and Wilson , J. G. 1998 . The chemistry of neutron capture therapy . Chem. Rev. , 98 : 1515 – 1562 . [PUBMED] [INFOTRIEVE] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Walsh , P. C. , Retik , A. B. , Stamey , T. A. and Vaughan , E. D. 1992 . Campbell's Urology , 6th Ed. Vol. 1 , 812 Philadelphia : Saunders .
   Google Scholar
• Barth , R. E. 2003 . A critical assessment of neutron capture therapy; an overview . J. Neuroncol. , 62 : 1 – 5 . [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Gupta , N. , Gahbauer , R. A. , Blue , T. E. and Albetson , B. 2003 . Common challenges and problems in clinical trials of boron neutron capture therapy . J. Neuroncol. , 62 : 197 – 210 . [CROSSREF]
   PubMedGoogle Scholar
• Allen , B. J. 1993 . Maximum therapeutic depth in thermal neutron capture therapy . Strahlenther. Onkol. , 169 : 34 – 41 . [PUBMED] [INFOTRIEVE]
   PubMedGoogle Scholar
• Ghabriel , M. N. , Lu , J. J. , Hermanis , G. , Zhu , C. and Setchell , B. P. 2002 . Expression of a blood–brain barrier‐specific antigen in the reproductive tract of the male rat . Reproduction , 23 : 389 – 397 . [CROSSREF]
   Google Scholar
• Fulmer , B. R. and Turner , T. T. 2000 . A blood–prostate barrier restricts cell and molecular movement across the rat ventral prostate epithelium . J. Urol. , 163 : 1591 – 1594 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Yamamoto , Y. , Seko , T. , Nakamura , H. , Nemoto , H. , Hojo , H. , Mukai , N. and Hashimoto , Y. 1992 . Synthesis of carborane containing nucleoside bases. Unexpectedly cytostatic and cytocidal toxicity towards cancer cells . J. Chem. Soc., Chem. Commun. , : 157 – 158 . [CROSSREF] [CSA]
   Google Scholar
• Schinazi , R. F. , Goudgaon , N. M. , Fulcrand , G. , El Kattan , Y. , Lesnikowski , Z. J. , Ullas , G. V. , Moravek , J. and Liotta , D. C. 1994 . Cellular pharmacology and biological activity of 5‐carboranyl‐2′‐deoxyuridine . Int. J. Radiat. Oncol. Biol. Phys. , 28 : 1113 – 1120 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Schinazi , R. F. , Hurwitz , S. J. , Liberman , I. , Juodawlkis , A. , Shi , J. , Liotta , D. C. , Coderre , J. and Olson , J. 2000 . Treatment of 9L gliosarcoma isografts with 5‐o‐carboranyl‐2′‐deoxyuridine neutron capture therapy . Clin. Cancer Res. , 6 : 725 – 730 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMedGoogle Scholar
• Goudgaon , N. M. , El‐Kattan , Y. A. , Xia , X. , McAtee , J. , Soria , J. , Wey , S. J. , Liotta , D. C. and Schinazi , R. F. 1997 . A general synthetic method of 5‐carboranyluracil nucleosides with potential antiviral activity and use in neutron capture therapy . Nucleosides Nucleotides Nucleic Acids , 16 : 2133 – 2150 .
   Web of Science ®Google Scholar
• Lesnikowski , Z. J. , Shi , J. and Schinazi , R. F. 1999 . Nucleic acids and nucleosides containing carboranes . J. Organomet. Chem. , 581 : 156 – 169 . [CROSSREF]
   Web of Science ®Google Scholar
• Mourier , N. S. , Eleuteri , A. , Hurwitz , S. J. and Schinazi , R. F. 1999 . Enantioselective synthesis and biological evaluation of new 5‐o‐carboranyl pyrimidine nucleosides . Bioorg. Med. Chem. , 7 : 2759 – 2766 . [PUBMED] [INFOTRIEVE] [CROSSREF]
   PubMedGoogle Scholar
• Lunato , A. J. , Wang , J. , Woollard , J. E. , Anisuzzaman , A. K.M. , Ji , W. , Rong , F. G. , Ikeda , S. , Soloway , A. H. , Eriksson , S. , Ives , D. H. , Blue , T. E. and Tjarks , W. 1999 . Synthesis of 5‐(carboranylalkylmercapto)‐2′‐deoxyuridines and their evaluation as substrates for human thymidine kinases 1 and 2 . J. Med. Chem. , 42 : 3378 – 3389 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMed Web of Science ®Google Scholar
• Hurwitz , S. J. , Ma , L. , Eleuteri , A. , Wright , J. , Moravek , J. and Schinazi , R. F. 2000 . Cellular pharmacology of the d‐ and l‐enantiomers of 5‐carboranyl‐2′‐deoxyuridine, boron delivery agents for neutron capture therapy . Nucleosides Nucleotides Nucleic Acids , 19 : 691 – 702 . [PUBMED] [INFOTRIEVE] [CSA]
   PubMed Web of Science ®Google Scholar
• Plagemann , P. G.W. and Wohlhueter , R. M. 1984 . Inhibition of the transport of adenosine, other nucleosides and hypoxanthine in Novidoff rat hepatoma cells by methylxanthines, papaverine, N6‐cyclohexyladenosine and N6‐phenylisopropyladenosine . Biochem. Pharmacol. , 33 : 1783 – 1788 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Mahony , W. B. , Domin , B. A. , McConnell , R. T. and Zimmerman , T. P. 1988 . Acyclovir transport in human erythrocytes . J. Biol. Chem. , 5 : 9285 – 9291 .
   Google Scholar
• Plagemann , P. G.W. , Wohlhueter , R. M. and Woffendin , C. 1988 . Nucleoside and nucleoside base transport in animal cells . Biochim. Biophys. Acta , 947 : 405 – 443 . [PUBMED] [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Domin , B. A. , Mahony , W. B. and Zimmerman , T. P. 1993 . Transport of 5‐fluorouracil and uracil into human erythrocytes . Biochem. Pharmacol. , 46 : 503 – 510 . [PUBMED] [INFOTRIEVE] [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kong , A. N. and Jusko , W. J. 1988 . Definitions and applications of mean transit and residence times in reference to the two‐compartment mammillary plasma clearance model . J. Pharm. Sci. , 77 : 157 – 165 . [PUBMED] [INFOTRIEVE]
   PubMedGoogle Scholar
• Jaragula , V. R. , Schinazi , R. F. , Fulcrand , G. , El‐Kattan , Y. , Liotta , D. C. and Boudinot , F. D. 1994 . Pharmacokinetics of 5‐carboranyl‐2′‐deoxyuridine in rats . J. Pharm. Sci. , 83 : 1697 – 1699 .
   PubMedGoogle Scholar
• Jain , R. K. 1987 . Transport of molecules in the tumor interstitium: a review . Cancer Res. , 48 : 3039 – 3051 .
   Google Scholar
• Goodman , J. H. , Yang , W. , Barth , R. F. , Gao , Z. , Boesel , C. P. , Staubus , A. E. , Gupta , N. , Gahbauer , R. A. , Adams , D. M. , Gibson , C. R. , Ferketich , A. K. , Moeschberger , M. L. , Soloway , A. H. , Carpenter , D. E. , Albertson , B. J. , Bauer , W. F. , Zhang , M. Z. and Wang , C. C. 2000 . Boron neutron capture therapy of brain tumors: biodistribution, pharmacokinetics, and radiation dosimetry of sodium borocaptate in patients with gliomas . Neurosurgery , 47 : 608 – 621 . discussion 621–622[PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Kageji , T. , Nagahiro , S. , Kitamura , K. , Nakagawa , Y. , Hatanaka , H. , Haritz , D. , Grochulla , F. , Haselsberger , K. and Gabel , D. 2001 . Optimal timing of neutron irradiation for boron neutron capture therapy after intravenous infusion of sodium borocaptate in patients with glioblastoma . Int. J. Radiat. Oncol. Biol. Phys. , 51 : 120 – 130 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Nguyen , T. , Brownell , G. L. , Holden , S. A. and Teicher , B. A. 1993 . Intracellular distribution of various boron compounds for use in boron neutron capture therapy . Biochem. Pharmacol. , 45 : 147 – 155 . [PUBMED] [INFOTRIEVE]
   PubMedGoogle Scholar
• Nguyen , T. , Brownell , G. L. , Holden , S. A. , Kahl , S. , Miura , M. and Teicher , B. A. 1993 . Subcellular distribution of various boron compounds and implications for their efficacy in boron neutron capture therapy by Monte Carlo simulations . Radiat. Res. , 133 : 33 – 40 . [PUBMED] [INFOTRIEVE]
   PubMedGoogle Scholar
• Capala , J. , Makar , M. S. and Coderre , J. A. 1996 . Accumulation of boron in malignant and normal cells incubated in vitro with boranophenylalanine, mercaptoborane or boric acid . Radiat. Res. , 146 : 554 – 560 . [PUBMED] [INFOTRIEVE]
   PubMedGoogle Scholar
• Ono , K. , Kinashi , Y. , Masunaga , S. , Suzuki , M. and Takagaki , M. 1998 . Electroporation increases the effect of borocaptate (10B‐BSH) in neutron capture therapy . Int. J. Radiat. Oncol. Biol. Phys. , 42 : 823 – 826 . [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
   PubMedGoogle Scholar
• Coderre , J. A. and Morris , G. M. 1999 . The radiation biology of boron neutron capture therapy . Radiat. Res. , 151 : 1 – 18 . [PUBMED] [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar