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Original Articles

DEAGGREGATION OF eIF4E INDUCED BY mRNA 5′ CAP BINDING

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Pages 507-511 | Published online: 15 Nov 2011

REFERENCES

  • Gingras , A. C. , Raught , B. and Sonenberg , N. 1999 . eIF4E initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation . Annu. Rev. Biochem , 68 : 913 – 963 .
  • Muthukrishnan , S. , Both , G. W. , Furuichi , Y. and Shatkin , A. J. 1975 . 5′-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation . Nature , 225 : 33 – 37 .
  • Ruszczynska , K. , Kamienska-Trela , K. , Wojcik , J. , Stepinski , J. , Darzynkiewicz , E. and Stolarski , R. 2003 . Charge distribution in 7-methylguanine regarding cation-pi interaction with protein factor eIF4E . Biophys. J. , 85 : 1450 – 1456 .
  • Sonenberg , N. 1988 . Cap-binding proteins of eukaryotic messenger RNA: functions in initiation and control of translation . Prog. Nucleic Acid Res. Mol. Biol. , 35 : 173 – 207 .
  • Konarska , M. M. , Padgett , R. A. and Sharp , P. A. 1984 . Recognition of cap structure in splicing in vitro of mRNA precursors . Cell , 38 : 731 – 736 .
  • Izaurralde , E. , Lewis , J. , McGuigan , C. , Jankowska , M. , Darzynkiewicz , E. and Mattaj , I. W. 1994 . A nuclear cap-binding protein complex involved in pre-mRNA splicing . Cell , 78 : 657 – 668 .
  • Izaurralde , E. , Lewis , J. , Gamberi , C. , Jarmolowski , A. , McGuigan , C. and Mattaj , I. W. 1995 . A cap-binding protein complex mediating U snRNA export . Nature , 376 : 709 – 712 .
  • Izaurralde , E. , Stepinski , J. , Darzynkiewicz , E. and Mattaj , I. W. 1992 . A cap-binding protein that may mediate nuclear export of RNA polymerase II-transcribed RNAs . J. Cell Biol. , 118 : 1287 – 1295 .
  • Lewis , J. D. and Izaurralde , E. 1997 . The role of the cap structure in RNA processing and nuclear export . Eur. J. Biochem. , 247 : 461 – 469 .
  • Sachs , A. B. , Sarnow , P. and Hentze , M. W. 1997 . Starting at the beginning, middle, and end: translation initiation in eukaryotes . Cell , 89 : 831 – 838 .
  • Sonenberg , N. , Morgan , M. A. , Merrick , W. C. and Shatkin , A. J. 1978 . A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5′ terminal cap in mRNA . Proc. Natl. Acad. Sci. U. S. A. , 75 : 4843 – 4847 .
  • Sonenberg , N. 1996 . “ mRNA 5′ cap-binding protein eIF4E and control of cell growth ” . In Translational Control , Edited by: Hershey , J. W.B. , Mathews , M. B. and Sonenberg , N. 245 – 269 . Cold Spring Harbor, NY : Cold Spring Harbor Laboratory .
  • Mader , S. , Lee , H. , Pause , A. and Sonenberg , N. 1995 . The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4gama and the translational repressors 4E-binding proteins . Mol. Cell. Biol. , 15 : 4990 – 4997 .
  • Altmann , M. , Schmitz , N. , Berset , C. and Trachsel , H. 1997 . A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E . EMBO J. , 16 : 1114 – 1121 .
  • Marcotrigiano , J. , Gingras , A. C. , Sonenberg , N. and Burley , S. K. 1999 . Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G . Mol. Cell , 3 : 707 – 716 .
  • Pause , A. , Methot , N. , Svitkin , Y. , Merrick , W. C. and Sonenberg , N. 1994 . Dominant negative mutants of mammalian translation initiation factor eIF4A define a critical fole for eIF-4F in cap-dependent and cap-independent translation . EMBO J. , 13 : 1205 – 1215 .
  • Lejbkowicz , F. , Goyer , C. , Darveau , A. , Neron , S. , Lemieux , R. and Sonenberg , N. 1992 . A fraction of the mRNA 5′ cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus . Proc. Natl. Acad. Sci. U. S. A. , 89 : 9612 – 9616 .
  • Strudwick , S. and Borden , K. L. 2002 . The emerging roles of translation factor eIF4E in the nucleus . Differentiation , 70 : 10 – 22 .
  • Dostie , J. , Lejbkowicz , F. and Sonenberg , N. 2000 . Nuclear eukaryotic initiation factor (eIF4E) colocalizes with splicing factors in speckles . J. Cell Biol. , 148 : 239 – 247 .
  • Darzynkiewicz , E. , Ekiel , I. , Tahara , S. M. , Seliger , L. S. and Shatkin , A. J. 1985 . Chemical synthesis and characterization of 7-methylguanosine cap analogues . Biochemistry , 24 : 1701 – 1707 .
  • Edery , I. , Altmann , M. and Sonenberg , N. 1988 . High-level synthesis in Escherichia coli of functional cap-binding eukaryotic initiation factor eIF-4E and affinity purification using a simplified cap-analogue resin . Gene , 74 : 517 – 525 .
  • Stern , B. D. , Wilson , M. and Jagus , R. 1993 . Use of nonreducing SDS-PAGE for monitoring renaturation of recombinant protein synthesis initiation factor, eIF-4alpha . Protein Expr. Purif. , 4 : 320 – 327 .
  • Niedzwiecka , A. , Marcotrigiano , J. , Stepinski , J. , Jankowska-Anyszka , M. , Wyslouch-Cieszynska , A. , Dadlez , M. , Gingras , A. C. , Mak , P. , Darzynkiewicz , E. , Sonenberg , N. , Burley , S. K. and Stolarski , R. 2002 . Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5′ cap structure and synthetic fragments of eIF4G and 4E-BP1 . J. Mol. Biol. , 319 : 615 – 635 .
  • Marcotrigiano , J. , Gingras , A. C. , Sonenberg , N. and Burley , S. K. 1997 . Cocrystal structure of the messenger RNA 5′ cap-binding protein (eIF4E) bound to 7-methyl-GDP . Cell , 89 : 951 – 961 .
  • Blachut-Okrasinska , E. , Bojarska , E. , Niedzwiecka , A. , Chlebicka , L. , Darzynkiewicz , E. , Stolarski , R. , Stepinski , J. and Antosiewicz , J. M. 2000 . Stopped-flow and Brownian dynamics studies of electrostatic effects in the kinetics of binding of 7-methyl-GpppG to the protein eIF4E . Eur. Biophys. J. , 29 : 487 – 498 .
  • Gingras , A. C. , Raught , B. , Gygi , S. P. , Niedzwiecka , A. , Miron , M. , Burley , S. K. , Polakiewicz , R. D. , Wyslouch-Cieszynska , A. , Aebersold , R. and Sonenberg , N. 2001 . Hierarchical phosphorylation of the translation inhibitor 4E-BP1 . Genes Dev. , 15 : 2852 – 2864 .
  • Niedzwiecka , A. , Stepinski , J. , Darzynkiewicz , E. , Sonenberg , N. and Stolarski , R. 2002 . Positive heat capacity change upon specific binding of translation initiation factor eIF4E to mRNA 5′ cap . Biochemistry , 41 : 12140 – 12148 .
  • Zuberek , J. , Wyslouch-Cieszynska , A. , Niedzwiecka , A. , Dadlez , M. , Stepinski , J. , Augustyniak , W. , Gingras , A. C. , Zhang , Z. , Burley , S. K. , Sonenberg , N. , Stolarski , R. and Darzynkiewicz , E. 2003 . Phosphorylation of eIF4E attenuates its interaction with mRNA 5′ cap analogs by electrostatic repulsion: intein-mediated protein ligation strategy to obtain phosphorylated protein . RNA , 9 : 52 – 61 .
  • Jemielity , J. , Fowler , T. , Zuberek , J. , Stepinski , J. , Lewdorowicz , M. , Niedzwiecka , A. , Stolarski , R. , Darzynkiewicz , E. and Rhoads , R. E. 2003 . Novel “anti-reverse” cap analogs with superior translational properties . RNA , 9 : 1108 – 1122 .
  • Zuberek , J. , Jemielity , J. , Jablonowska , A. , Stepinski , J. , Dadlez , M. , Stolarski , R. and Darzynkiewicz , E. 2004 . Influence of electric charge variation at residues 209 and 259 on the interaction of eIF4E with the mRNA 5′ terminus . Biochemisty , 43 : 5370 – 5379 .
  • von der Haar , T. , Ball , P. D. and McCarthy , J. E. 2000 . Stabilization of eukaryotic initiation factor 4E binding to the mRNA 5′ -cap by domains of eIF4G . J. Biol. Chem. , 275 : 30551 – 30555 .

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