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Research Article

Preformulation Studies and Characterization of Proposed Chondroprotective Agents: Glucosamine HCl and Chondroitin Sulfate

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Pages 457-469 | Received 10 Nov 2001, Accepted 13 Apr 2002, Published online: 12 Feb 2002

REFERENCES

  • Davis W.M. The Role of Glucosamine and Chondroitin Sulfate in the Management of Arthritis. Drug Top. 1998; 142: 3S–13S
  • Smalley W.E., Ray W.A., Daugherty J.R., Griffin M.R. Nonsteroidal Anti-inflammatory Drugs and the Incidence of Hospitalizations for Peptic Ulcer Disease in Elderly Persons. Am. J. Epidemiol. 1995; 141: 539–545
  • Palmoski M.J., Brandt K.D. Effects of Some Nonsteroidal Antiinflammatory Drugs on Proteoglycan Metabolism and Organization in Canine Articular Cartilage. Arthritis Rheum. 1980; 23: 1010–1020
  • Leeb B.F., Petera P., Neumann K. Open Trial with Chondroitin Sulfate in the Treatment of Osteoarthritis of the Hip-, Knee-, and Finger Joints (In German). Wien. Med. Wochenschr. 1996; 146: 609–614
  • Shankland W.E. The Effects of Glucosamine and Chondroitin Sulfate on Osteoarthritis of the TMJ: A Preliminary Report of 50 Patients. Cranio 1998; 16: 230–235
  • Qiu G.X., Gao S.N., Giacovelli G., Rovati L., Setnikar I. Efficacy and Safety of Glucosamine Sulfate Versus Ibuprofen in Patients with Knee Osteoarthritis. Arzneim-Forsch. 1998; 48: 467–474
  • Leffler C.T., Philippi A.F., Leffler S.G., Mosure J.C., Kim P.D. Glucosamine, Chondroitin, and Manganese Ascorbate for Degenerative Joint Disease of the Knee or Low Back: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. Mil. Med. 1999; 164: 85–91
  • Karzel K., Domenjoz R. Effects of Hexosamine Derivatives and Uronic Acid Derivatives on Glycosaminoglycane Metabolism of Fibroblast Cultures. Pharmacology 1971; 5: 337–345
  • Wasteson A. Properties of Fractionated Chondroitin Sulphate from Ox Nasal Septa. Biochem. J. 1971; 122: 477–485
  • Toledo O.M., Dietrich C.P. Tissue Specific Distribution of Sulfated Mucopolysaccharides in Mammals. Biochim. Biophys. Acta 1977; 487: 114–122
  • Ebube N.K., Hikal A., Wyandt C.M., Beer D.C., Miller L.G., Jones A.B. Effect of Drug, Formulation and Process Variables on Granulation and Compaction Characteristics of Heterogeneous Matrices. Part 1: HPMC and HPC Systems. Int. J. Pharm. 1997; 156: 49–57
  • Phadke D.S., Anderson N.R. Effect of Crospovidone on the Wet Granulation Aspects of Acetaminophen. Drug Dev. Ind. Pharm. 1990; 16: 983–994
  • Carr R.L. Evaluating Flow Properties of Solids. Chem. Eng. 1965; 72: 163–168
  • Augsburger L.L., Brittain H.G., Byrn S.R., Fox C.D., Peck G.E., Wurster D.E. Physical Test Methods for Powder Flow Characterization of Pharmaceutical Materials: A Review of Methods. Pharmacop. Forum 1999; 25: 8298–8306
  • Adolfsson A., Gustafsson C., Nystrom C. Use of Tablet Tensile Strength Adjusted for Surface Area and Mean Interparticulate Distance to Evaluate Dominating Bonding Mechanisms. Drug Dev. Ind. Pharm. 1999; 25: 753–754
  • Heckel R.W. Density–Pressure Relationships in Powder Compaction. Trans. Met. Soc. AIME 1961; 221: 671–675
  • Olmo I.G., Ghaly E.S. Compressional Characterization of Two Dextrose-Based Directly Compressible Excipients Using an Instrumented Tablet Press. Pharm. Dev. Technol. 1999; 4: 221–231
  • Oksanen C.A., Zografi G. The Relationship Between the Glass Transition Temperature and Water Vapor Absorption by Poly(Vinylpyrrolidone). Pharm. Res. 1990; 7: 654–657
  • Marshall K. L. Lachman, H.A. Lieberman, J.L. KanigCompression and Consolidation of Powdered Solids. The Theory and Practice of Industrial Pharmacy, . Lea and Febiger, Philadelphia 1986; 82–83

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