76
Views
16
CrossRef citations to date
0
Altmetric
Original

PROTHROMBIN 20210 G: A MUTATION AND FACTOR V LEIDEN MUTATION IN WOMEN WITH A HISTORY OF SEVERE PREECLAMPSIA AND (H)ELLP SYNDROME*

, , , , &
Pages 291-298 | Published online: 07 Jul 2009

REFERENCES

  • Dekker G. A., de Vries J. I., Doelitzsch P. M., Huijgens P. C., von Blomberg B. M., Jakobs C., van Geijn H. P. Underlying Disorders Associated with Severe Early-Onset Preeclampsia. Am. J. Obstet. Gynecol. 1995; 173(4)1042–1048
  • Preston F. E., Rosendaal F. R., Walker I. D., Briet E., Berntorp E., Conard J., Fontcuberta J., Makris M., Mariani G., Noteboom W., Pabinger I., Legnani C., Scharrer I., Schulman S., van der Meer F. J. Increased Fetal Loss in Women with Heritable Thrombophilia. Lancet 1996; 348(9032)913–916
  • van Pampus M. G., Dekker G. A., Wolf H., Huijgens P. C., Koopman M. M., von Blomberg B. M., Buller H. R. High Prevalence of Hemostatic Abnormalities in Women with a History of Severe Preeclampsia. Am. J. Obstet. Gynecol. 1999; 180(5)1146–1150
  • Bertina R. M. Factor V Leiden and Other Coagulation Factor Mutations Affecting Thrombotic Risk. Clin. Chem. 1997; 43(9)1678–1683
  • Howard T. E., Marusa M., Boisza J., Young A., Sequeira J., Channell C., Guy C., Benson E., Duncan A. The Prothrombin Gene 3′-Untranslated Region Mutation Is Frequently Associated with Factor V Leiden in Thrombophilic Patients and Shows Ethnic-Specific Variation in Allele Frequency. Blood 1998; 91(3)1092
  • Ehrenforth S., Ludwig G., Klinke S., Krause M., Scharrer I., Nowak-Gottl U. The Prothrombin 20210 A Allele Is Frequently Coinherited in Young Carriers of the Factor V Arg 506 to Gln Mutation with Venous Thrombophilia. Blood 1998; 91(6)2209–2210
  • Brenner B., Mandel H., Lanir N., Younis J., Rothbart H., Ohel G., Blumenfeld Z. Activated Protein C Resistance Can Be Associated with Recurrent Fetal Loss. Br. J. Haematol. 1997; 97(3)551–554
  • Rotmensch S., Liberati M., Mittlemann M., Ben-Rafael Z. Activated Protein C Resistance and Adverse Pregnancy Outcome. Am. J. Obstet. Gynecol. 1997; 177(1)170–173
  • Dizon-Townson D. S., Nelson L. M., Easton K., Ward K. The Factor V Leiden Mutation May Predispose Women to Severe Preeclampsia. Am. J. Obstet. Gynecol. 1996; 175(4 Pt. 1)902–905
  • Dizon-Townson D. S., Meline L., Nelson L. M., Varner M., Ward K. Fetal Carriers of the Factor V Leiden Mutation Are Prone to Miscarriage and Placental Infarction. Am. J. Obstet. Gynecol. 1997; 177(2)402–405
  • Grandone E., Margaglione M., Colaizzo D., d'Addedda M., Cappucci G., Vecchione G., Scianname N., Pavone G., Di Minno G. Factor V Leiden is Associated with Repeated and Recurrent Unexplained Fetal Losses. Thromb. Haemost. 1997; 77(5)822–824
  • Meinardi J. R., Middeldorp S., de Kam P. J., Koopman M. M., van Pampus E. C., Hamulyák K., Prins M. H., Buller H. R., van der Meer J. Increased Risk for Fetal Loss in Carriers of the Factor V Leiden Mutation. Ann. Intern. Med. 1999; 130(9)736–739
  • Kupferminc M. J., Eldor A., Steinman N., Many A., Bar-Am A., Jaffa A., Fait G., Lessing J. B. Increased Frequency of Genetic Thrombophilia in Women with Complications of Pregnancy. N. Engl. J. Med. 1999; 340(1)9–13
  • Gris J. C., Qur I., Monpeyroux F., Mercier E., Ripart-Neveu S., Tailland M. L., Hoffet M., Berlan J., Daures J. P., Mares P. Case-Control Study of the Frequency of Thrombophilic Disorders in Couples with Late Foetal Loss and No Thrombotic Antecedent—The Nimes Obstetricians and Haematologists Study 5 (NOHA5). Thromb. Haemost. 1999; 81(6)891–899
  • De Groot C. J., Bloemenkamp K. W., Duvekot E. J., Helmerhorst F. M., Bertina R. M., Van Der Meer F., De Ronde H., Oei S. G., Kanhai H. H., Rosendaal F. R. Preeclampsia and Genetic Risk Factors for Thrombosis: A Case-Control Study. Am. J. Obstet. Gynecol. 1999; 181(4)975–980
  • Sibai B. M. The HELLP Syndrome (Hemolysis, Elevated Liver Enzymes, and Low Platelets): Much Ado About Nothing?. Am. J. Obstet. Gynecol. 1990; 162(2)311–316
  • Poort S. R., Rosendaal F. R., Reitsma P. H., Bertina R. M. A Common Genetic Variation in the 3′-Untranslated Region of the Prothrombin Gene is Associated with Elevated Plasma Prothrombin Levels and an Increase in Venous Thrombosis. Blood 1996; 88(10)3698–3703
  • Voorberg J., Roelse J., Koopman R., Buller H., Berends F., ten Cate J. W., Mertens K., van Mourik J. A. Association of Idiopathic Venous Thromboembolism with Single Point-Mutation at Arg506 of Factor V. Lancet 1994; 343(8912)1535–1536
  • Rosendaal F. R., Siscovick D. S., Schwartz S. M., Psaty B. M., Raghunathan T. E., Vos H. L. A Common Prothrombin Variant (20210 G to A) Increases the Risk of Myocardial Infarction in Young Women. Blood 1997; 90(5)1747–1750
  • Rosendaal F. R., Siscovick D. S., Schwartz S. M., Beverly R. K., Psaty B. M., Longstreth W. T., Jr., Raghunathan T. E., Koepsell T. D., Reitsma P. H. Factor V Leiden (Resistance to Activated Protein C) Increases the Risk of Myocardial Infarction in Young Women. Blood 1997; 89(8)2817–2821
  • Doggen C. J., Cats V. M., Bertina R. M., Rosendaal F. R. Interaction of Coagulation Defects and Cardiovascular Risk Factors: Increased Risk of Myocardial Infarction Associated with Factor V Leiden or Prothrombin 20210A. Circulation 1998; 97(11)1037–1041
  • Arruda V. R., Siquiera L. H., Chiaparini L. C., Coelho O. R., Mansur A. P., Ramires A., Annichino-Bizzacchi J. M. Prevalence of the Prothrombin Gene Variant 20210 G→A Among Patients with Myocardial Infarction. Cardiovasc. Res. 1998; 37(1)42–45

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.