REFERENCES
- Isreal , E. , Dermarkarian , R. , Rosenberg , M. , Sperling , R. , Taylor , G. , Rubin , P. and Drazen , J. M. 1990 . N. Engl. J. Med. , 323 : 1740
- Isreal , E. , Drazen , J. , Pearlman , H. , Cohn , J. and Rubin , P. 1992 . J. Allergy Clin. Immunol. , 89 : 236
- Lewis , R. A. , Austen , K. F. and Soberman , R. J. 1991 . N. Engl. J. Med. , 323 : 645
- Collawn , C. , Rubin , P. , Perez , H. , Bobadilla , J. , Cabrera , G. , Reyes , E. , Borovoy , J. and Kershenobich , D. 1992 . Am. J. Gasteroenterol , 87 : 342
- Ku , Y. , Patel , R. , Roden , B. and Sawick , D. 1994 . Tetrahedron Lett. , 35 : 6017
- Kolasa , T. and Brooks , D. W. 1993 . Synthetic Commun. , 23 : 743 and references cited therein
- Basha , A. , Henry , R. , McLaughlin , M. , Ratajczyk , J. and Wittenberger , S. 1994 . J. Org. Chem. , 59 : 6103
- Rohloff , J. , Alfredson , T. and Schwartz , M. 1994 . Tetrahedron Lett. , 35 : 1011
- Garigipati , R. , Sorenson , M. , Erhard , K. and Adams , J. 1993 . Tetrahedron Lett. , 34 : 5537 For the resolution of enantiomers see
- Summers , J. , Gunn , B. and Brooks , D. W. U.S. Patent, 4,873,259 . Oct. 10, 1991 .
- Flisak , J. , Lantos , I. , Liu , L. , Matsuoka , W. , Mendelson , W. , Tucker , L. , Villani , A. and Zhang , W. 1996 . Tetrahedron Lett. , 37 : 4639 and references cited therein
- Several protic acids with pKa's at or below 2 have been demonstrated to efficiently effect the alkylation
- Alvarez , F. and Slade , R. 1992 . Pharm. Res. , 9 : 1465 For a study on acid degradation of Zileuton see
- Hengeveld , J. and et. al. U.S. Patent 6,080,874 . June 27, 2000 .
- Stewart , A. O. and et. al. 1997 . J. Med. Chem. , 40 : 1955 – 1968 .
- Basha , A. , Ratajczyk , J. and Brooks , D. 1991 . Tetrahedron Lett. , 32 : 3783