Quantitative Determination of Ca²⁺ Effects on Endotoxin Removal and Protein Yield in a Two-Stage Ultrafiltration Process

REFERENCES

• Vaara , M. and Nikaido , H. 1984 . “ Molecular Organization of Bacterial Outer Membrane ” . In Handbook of Endotoxin Chemistry of Endotoxin Edited by: Rietschel , E. T. Vol. 1 , 1 New York , NY : Elsevier .
   Google Scholar
• Baggerman , C. , Pathmamanoharan , C. , Spies , F. , Joosten , J. G. H. and Junginer , H. E. 1985 . Physicochemical Properties of Endotoxins in Large Volume Parenterals . J. Pharm. Pharmacol. , 37 : 521 – 527 .
   PubMed Web of Science ®Google Scholar
• Evans-Strickfaden , T. T. , Oshima , K. H. , Highsmith , A. K. and Ades , E. W. 1996 . Endotoxin Removal Using 6,000 Molecular Weight Cut-off Polyacrylonitrile (PAN) and Polysulfone (PS) Hollow Fiber Ultrafilters . PDA J. Pharm. Sci. Technol. , 50 ( 3 ) : 154 – 157 .
   PubMedGoogle Scholar
• Gerba , C. P. and Goyal , S. M. 1981 . “ Potential for Groundwater Contamination by Algal Endotoxins ” . In The Water Environment, Algal Toxins and Health Edited by: Carmichael , W. W. 303 – 314 . New York , NY : Plenum Press .
   Google Scholar
• Enterline , P. E. , Sykora , J. L. , Keleti , G. and Lange , J. H. 1985 . Endotoxins, Cotton Dust, and Cancer . Lancet , 2 : 934 – 935 .
   PubMed Web of Science ®Google Scholar
• Zielger , E. J. , McCutchan , J. A. , Fierer , J. , Glauser , M. P. , Sadoff , J. C. , Douglas , H. and Braude , A. I. 1982 . Treatment of Gram-Negative Bacteremia and Shock with Human Antiserum to a Mutant Escherichia coli . New Engl. J. Med. , 307 : 1225 – 1230 .
   PubMed Web of Science ®Google Scholar
• Ziegler , E. J. , Fisher , C. J. Jr. , Sprung , C. L. , Straube , R. C. , Sadoff , J. C. , Foulke , G. E. , Wortel , C. H. , Fink , M. P. , Dellinger , H. J. , Teng , N. N.H. , Allen , I. E. , Berger , H. J. , Knatterud , G. L. , LoBuglio , A. F. and Smith , C. R. 1991 . the HA-1A Sepsis Study Group, “Treatment of Gram-Negative Bacteremia and Septic Shock with HA-1A Human Monoclonal Antibody against Endotoxin,” . Ibid. , 324 : 429 – 436 .
   Google Scholar
• Schumann , R. R. , Leong , S. R. , Flaggs , G. W. , Gray , P. W. , Wright , S. D. , Mathison , J. C. , Tobias , P. S. and Ulevitch , R. J. 1990 . Structure and Function of Lipopolysaccharide Binding Protein . Science , 249 : 1429 – 1431 .
   PubMed Web of Science ®Google Scholar
• Wakitu , M. , Adachi , T. , Ida , J. and Hashimoto , M. 1996 . Selective Adsorption of Lipopolysaccharide from Protein Solutions by Porous Supports Bearing Cationic Lipid Membranes . Bull. Chem. Soc. Jpn. , 69 : 1017 – 1021 .
   Web of Science ®Google Scholar
• Schlichting , E. , Aspeliln , T. and Lyberg , T. 1996 . Interactions of Endotoxin with Human Blood Cells and Serum Proteins . Scand. J. Clin. Lab. Invest. , 56 ( 2 ) : 167 – 176 .
   PubMed Web of Science ®Google Scholar
• Kaca , W. , Roth , R. I. and Levin , J. 1994 . Hemoglobin, A Newly Recognized Lipopolysaccharide (LPS)-Binding Protein that Enhances LPS Biological Activity . J. Biol. Chem. , 269 : 25078 – 25084 .
   PubMed Web of Science ®Google Scholar
• Roth , R. I. , Kaca , W. and Levin , J. 1994 . “ Hemoglobin: A Newly Recognized Binding Protein for Bacterial Endotoxin (LPS) ” . In Bacterial Endotoxins: Basic Science to Anti-Sepsis Strategies Edited by: Bean , C. 161 – 172 . New York , NY : Wiley-Liss .
   Google Scholar
• Li , L. and Luo , R. G. 1997 . Protein Concentration Effect on Protein–Lipopolysaccharide (LPS) Binding and Endotoxin Removal . Biotechnol. Lett. , 19 ( 2 ) : 135 – 138 .
   Web of Science ®Google Scholar
• Brown , S. and Fuller , A. C. 1993 . Depyrogenation of Pharmaceutical Solutions Using Submicron and Ultrafilters . J. Parenter. Sci. Technol. , 47 ( 6 ) : 285 – 288 .
   PubMedGoogle Scholar
• Abramson , D. , Butler , L. D. and Chrai , S. 1981 . Depyrogenation of a Parenteral Solution by Ultrafiltration . Ibid. , 35 ( 1 ) : 3 – 7 .
   Google Scholar
• Sweadner , K. J. , Forte , M. and Nelsen , L. L. 1977 . Filtration Removal of Endotoxin (pyrogens) in Solution in Different States of Aggregation . Appl. Environ. Microbiol. , 34 ( 4 ) : 382 – 385 .
   PubMed Web of Science ®Google Scholar
• Hannecart-Pokorni , E. , Dekegel , D. and Dupuydt , F. 1973 . Macromolecular Structure of Lipopolysaccharides from Gram-Negative Bacteria . Eur. J. Biochem. , 38 : 6
   PubMedGoogle Scholar
• Schindler , M. and Osborn , M. J. 1979 . Interaction of Divalent Cations and Polymyxin B with Lipopolysaccharide . Biochemistry , 18 ( 20 ) : 4425 – 4430 .
   PubMed Web of Science ®Google Scholar
• Nelsen , L. L. 1978 . Removal of Pyrogens from Parenteral Solutions by Ultrafiltration . Pharm. Tech. , 2 ( 5 ) : 46 – 49 .
   Google Scholar
• Pearson , F. C. 1985 . Pyrogens: Endotoxins, LAL Testing, and Depyrogenation 29 New York , NY : Dekker .
   Google Scholar
• Kang , y. and Luo , R. G. 1998 . Chromatographic Removal of Endotoxin from Hemoglobin Preparations—Effects of Solution Conditions on Endotoxin Removal Efficiency and Protein Recovery . J. Chromatogr. A , 809 : 13 – 20 .
   PubMed Web of Science ®Google Scholar
• Li , L. and Luo , R. G. Use of Ca+2 to Re-Aggregate Lipopolysaccharide (LPS) in Hemoglobin Solutions and the Subsequent Removal of Endotoxin by Ultrafiltration . Biotechnol. Tech. , 12 ( 2 ) 119 – 122 .
   Google Scholar