Risk of Exposure to and Mitigation of Effect of Aflatoxin on Human Health: A West African Example

References

• Bandyopadhyay R., Cardwell K. F. Species of Trichoderma and Aspergillus as biological control agents against plant diseases in Africa. Biological Control in Integrated Pest Management Systems in Africa, P. Neuenschwander, C. Borgemeister, J. Langewald. CABI Publishing, Wallingford 2004, In press
   Google Scholar
• Bayman P., Cotty P. J. Genetic diversity in Aspergillus flavus: association with aflatoxin production and morphology. Can. J. Bot. 1993; 71: 23–24
   Google Scholar
• Bilgrami K. S., Choudhary A. K. Mycotoxins in preharvest contamination of agricultural crops. Mycotoxins in Agriculture and Food Safety, Sinha, Bhatnagar. Marcel Dekker, Inc., New York 1998; 1–43
   Google Scholar
• Bondy G. S., Pestka J. J. Immunomodulation by fungal toxins. J. Toxicol. Environ. Health 2000; 83: 109–143
   Google Scholar
• Bosque‐Pérez N. A., Schulthess F. Maize: West and Central Africa. African Cereal Stem Borer: Economic Importance, Taxonomy, Natural Enemies and Control, A. Polaszek. CAB International, England 1998; 11–24, 530
   Google Scholar
• Brown R. L., Chen Z.‐Y., Menkir A., Cleveland T. E., Cardwell K., Kling J., White D. G. Resistance to aflatoxin accumulation in kernels of maize inbreds selected for ear rot resistance in West and Central Africa. J. Food Prot. 2001; 64: 396–400, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Cardwell K. F. Mycotoxin contamination in foods in Africa: antinutritional factors. Food Nutr. Bull. 2000; 21: 488–493
   Google Scholar
• Cardwell K. F., Cotty P. J. Interactions among U.S. and African Aspergillus spp. strains: influence on aflatoxin production. Phytopathology 2000; 90: 11
   Google Scholar
• Cardwell K. F., Cotty P. J. Distribution of Aspergillus section Flavi among field soils from the four agroecological zones of the Republic of Benin, West Africa. Plant Dis. 2002; 86: 434–439
   PubMed Web of Science ®Google Scholar
• Cardwell K. F., Kling J. G., Maziya‐Dixon B., Bosque‐Perez N. Interactions between Fusarium verticillioides, Aspergillus flavus and insects in improved maize populations in lowland Africa. Phytopathology 2000; 90: 276–284
   PubMed Web of Science ®Google Scholar
• Cardwell K. F., Desjardins A. E., Henry S. M., Munkvold G., Robens J. Mycotoxins: the cost of achieving food security and food quality. 2001; 1–25, APSNet Feature Story August: http://www.apsnet.org/online/feature/mycotoxin/top.html
   Google Scholar
• Coker R. D. Design of sampling plans for determination of mycotoxins in foods and feeds. Mycotoxins in Agriculture and Food Safety, Sinha, Bhatnagar. Marcel Dekker, Inc., New York 1998, pp. 1–43, 109–133
   Google Scholar
• Cole R., Dorner J. W. Biological control of aflatoxin and cyclopiazonic acid contamination of peanuts. Mycotoxin Contamination: Health Risk and Prevention Project, S. Kumagai, et al. Japanese Association of Mycotoxicology, Tokyo 2000; 70–73
   Google Scholar
• Cotty P. J. Aflatoxin‐producing potential of communities of Aspergillus section Flavi from cotton producing areas in the United States. Mycol. Res. 1997; 101: 698–704, [CROSSREF]
   Web of Science ®Google Scholar
• Cotty P. J., Cardwell K. F. Divergence of West African and North American communities of Aspergillus section Flavi. Appl. Environ. Microbiol. 1999; 65: 2264–2266, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Cotty P. J., Bayman P., Egel D. S., Elias K. S. Agriculture, aflatoxins, and Aspergillus. The Genus Aspergillus: From Taxonomy and Genetics to Industrial Applications, K. A. Powell, A. Renwick, J. F. Peabody. FEMS Symposium, Plenum Press. 1994; Vol. 69: 1–27
   Google Scholar
• Coulombe R. A. Non‐hepatic disposition and effects of aflatoxin B1. The Toxicology of Aflatoxins:Human Health, Veterinary and Agricultural Significance, D. A. Eaton, J. D. Groopman. Academic Press, San Diego, CA 1994; 89–98
   Google Scholar
• Dorner J. W., Cole R. J., Wicklow D. T. Aflatoxin reduction in corn throughfield application of competitive fungi. J. Food Prot. 1999; 62: 650–656, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Egal S., Hounsa A., Gong Y. Y., Turner P. C., Wild C. P., Hall A. J., Cardwell K. F. Dietary exposure to aflatoxin from maize and groundnut in Benin and Togo. Food Nutr. Agric. 2004, In press
   Google Scholar
• Evans A. A., O'Connell A. P., Puch J. C., Mason W. S., Shen F., Chen B.‐C., Lin W.‐Y., Dia A., Boup M.‐S., Dramé B., London W. T. Geographic variation in viral load among hepatitis B carriers with differing risks of hepatocellular carcinoma. Cancer Epidemiol. Biomark. Prev. 1998; 7: 559–565
   PubMed Web of Science ®Google Scholar
• Food and Drug Administration. Action levels for aflatoxin in animal feeds. Compliance Policy Guides CPG 7126:33, 384 (Section 683, 100), CPG 7106‐10 (sec 527.400), CPG 7120.26 (sec 555.400). Food and Drug Administration. 1996
   Google Scholar
• Gong Y. Y., Cardwell K. F., Hounsa A., Egal S., Turner P. C., Hall A. J., Wild C. P. Dietary aflatoxin exposure and impaired growth in young children from Benin and Togo: cross sectional study. Br. Med. J. 2002; 325: 20–21
   PubMed Web of Science ®Google Scholar
• Gong Y. Y., Egal S., Hounsa A., Turner P. C., Hall A. J., Cardwell K., Wild C. P. Determinants of aflatoxin exposure in young children from Benin and Togo, West Africa: the critical role of weaning and weaning foods. Int. J. Epidemiol. 2003, In press
   PubMed Web of Science ®Google Scholar
• Hall A. J., Wild C. P. Epidemiology of aflatoxin related disease. The Toxicology of Aflatoxins, D. L. Eaton, J. D. Groopman. Academic Press, San Diego, CA 1994; 233–258, 529
   Google Scholar
• Hell K., Cardwell K. F., Setamou M., Poehling H.‐M. The influence of storage practices on aflatoxin contamination of maize in four agroecological zones of Benin, West Africa. J. Stored Prod. Res. 2000a; 36: 365–382, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hell K., Cardwell K. F., Setamou M., Schulthess F. Influence of insect infestation on aflatoxin contamination of stored maize in four agroecological regions in Benin. Afr. Entomol. 2000b; 8: 169–177
   Web of Science ®Google Scholar
• Henry S. H., Bosch F. X. Foodborne disease and mycotoxin epidemiology. Foodborne Disease Handbook2nd ed., Hui, Smith, Spoerke, Jr. Marcel Dekker, New York 2001
   Google Scholar
• Hesseltine C. S., Shotwell O., Smith M., Ellis J. J., Vandegraft E., Shannon G. Production of various aflatoxins by strains of the Aspergillus flavus series. Proc. U.S.–Japan Conference on Toxic Microorganisms, M. Herzberg. U.S. Government Printing Office, Washington, DC 1970; 202–210
   Google Scholar
• Horn B. W., Greene R. L., Sorensen R. B., Blankenship P. D., Dorner J. W. Conidial movement of nontoxigenic Aspergillus flavus and A. parasiticus in peanut fields following application to soil. Mycopathologia 2001; 151: 81–92, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hunt J. Agricultural research as a public investment. Food Nutr. Bull. 2000; 21: 562
   Google Scholar
• IARC. Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC Monographs on the Evaluation of Carcinogenic Risks of Chemicals to Humans. International Agency for Research on Cancer, Lyon 1993; Vol. 56: 245–395
   Google Scholar
• Joint FAO/WHO Expert Committee on Food Additives (JECFA). Safety Evaluation of Certain Food Additives. WHO Food Additive Series, International Program on Chemical Safety, World Health Organization, Geneva 1998; Vol. 40
   Google Scholar
• Joint FAO/WHO Expert Committee on Food Additives (JECFA). Evaluation of certain mycotoxins in food. Estimates of M1 in diet in various parts of the world. WHO Food Additives Series 47. FAP Food and Nutrition Paper 74 2002; 906: 1–54
   Google Scholar
• Klich M. A., Tiffany L. H., Knaphus G. Ecology of the aspergilli of soils and litter. Aspergillus: Biology and Industrial Applications, J. W. Bennett, M. A. Klich. Butterworth‐Heineman, Stoneham, MA 1992; 327–351
   Google Scholar
• Krishnamachari K. A., Bhat R. V., Nagarajan V., Tilak T. B.G. Hepatitis due to aflatoxicosis. An outbreak in Western India. Lancet 1975; I: 1061–1063, [CROSSREF]
   Google Scholar
• Kuiper‐Goodman T. Prevention of human mycotoxicoses through risk assessment and risk management. Mycotoxins in Grains: Compounds Other Than Aflatoxin, J. D. Miller, H. L. Trenholm. Eagan Press, St. Paul 1994; 439–469
   Google Scholar
• Lacey J. Aspergilli in feeds and seeds. The Genus Aspergillus: From Taxonomy and Genetics Industrial Applications, K. A. Powell, A. Renwick, J. Peabody, 1994; 73–92
   Google Scholar
• Lee M.‐S., Kim D.‐H., Kim H.‐S., Kim C.‐Y., Park T.‐S., Yoo K.‐Y., Park B.‐J., Ahn Y.‐O. Hepatitis B vaccination and reduced risk of primary liver cancer among male adults: a cohort study in Korea. Int. J. Epidemiol. 1998; 27: 316, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Linsell C. A., Peers F. G. Aflatoxin and liver cell cancer. Trans. R. Soc. Trop. Med. Hyg. 1977; 71: 471–473, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lopez‐Garcia R., Park D. L. Effectiveness of postharvest procedures in management of mycotoxin hazards. Mycotoxins in Agriculture and Food Safety, K. K. Sinha, D. Bhatnagar. Marcel Dekker, Inc., New York 1998; 407–435
   Google Scholar
• Massey T. E., Stewart R. K., Daniels J. M., Liu L. Biochemical and molecular aspects of mammalian susceptibility to aflatoxin B1 carcinogenesis. Proc. Soc. Exp. Biol. Med. 1995; 208: 213–227, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Miller D. M., Wilson D. M. Veterinary diseases related to aflatoxins. The Toxicology of Aflatoxins: Human Health, Veterinary, and Agricultural, D. Eaton, J. Groopman. Acad Press, San Diego, CA 1994; 347–367
   Google Scholar
• Moore S. E., Cole T. J., Collinson A. C., Poskitt E. M.E., McGregor I. A., Prentice A. M. Prenatal or early postnatal events predict infectious deaths in young adulthood in rural Africa. Int. J. Epidemiol. 1999; 28: 1088–1095, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Munkvold G. P. Mycotoxins in corn: occurrence, impacts, and management. Corn Chemistry and Technology2nd ed., P. White, L. Johnson. Am. Assoc. Cereal Chemists, St. Paul, MN 2003, Chapter 23
   Google Scholar
• Nagindu A., Johnson B. K., Kenya P. R., Ngira J. A., Ooheng D. M., Nandwa H., Omunid T. N., Jansen A. J., Ngare W., Kaviti J. N., Gatei D., Siongok T. A. Outbreak of acute hepatitis caused by aflatoxin poisoning in Kenya. Lancet 1982; I: 1346–1348, [CROSSREF]
   Google Scholar
• Ngoko Z., Marasas W. F.O., Rheeder J. P., Shephard G. S., Wingfield M. J., Cardwell K. F. Fungal infection and mycotoxin contamination of maize in the humid forest and the western highlands of Cameroon. Phytoparasitica 2001; 29: 352–360
   Web of Science ®Google Scholar
• Odvody G. N., Spencer N., Remers J. A. Description of silk cut, a stress‐related loss of kernel integrity in preharvest maize. Plant Dis. 1997; 81: 439–444
   PubMed Web of Science ®Google Scholar
• Otsuki T., Wilson J. S., Sewadeh M. Saving two in a billion: quantifying the trade effect of European food safety standards on African exports. Food Policy 2001; 26: 495–514, [CROSSREF]
   Web of Science ®Google Scholar
• Payne G. Process of contamination by aflatoxin‐producing fungi and their impact on crops. Mycotoxins in Agriculture and Food Safety, K. K. Sinha, D. Bhatnagar. Marcel Dekker, Inc., Basel 1998, pp. 270–307, 511
   Google Scholar
• Peers F., Linsell A. Dietary aflatoxins and liver cancer. Br. J. Cancer 1973; 27: 473–484, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Peers F., Bosch X., Kaldor J., Linsell A., Pluijment M. Aflatoxin exposure, hepatitis B virus infection, and liver cancer in Swaziland. Int. J. Cancer 1987; 39: 545–553, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Pestka J. J., Bondy G. S. Immunotoxic effects of mycotoxins. Mycotoxins in Grains: Compounds Other Than Aflatoxin, J. D. Miller, H. L. Trenholm. Eagan Press, St. Paul 1994; 339–359
   Google Scholar
• Qian G.‐S., Ross R. K., Yu M. C., Yuan J.‐M., Gao Y.‐T., Henderson B. E., Wogan G. N., Groopman J. D. A follow‐up study of urinary markers of aflatoxin exposure and liver cancer in Shanghai, People's Republic of China. Cancer Epidemiol. Biomark. Prev. 1994; 3: 3–10
   PubMed Web of Science ®Google Scholar
• Roebuck B. D., Maxuitenko Y. Y. Biochemical mechanisms and biological implications for the toxicity of aflatoxin as related to aflatoxin carcinogenesis. The Toxicology of Aflatoxins, D. L. Eaton, J. D. Groopman. Academic Press, San Diego, CA 1994; 529
   Google Scholar
• Ross R. K., Yuan J.‐M., Yu M. C., Wogan G. N., Qian G.‐S., Tu J. T., Groopman J. D., Gao Y.‐T., Henderson B. E. Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma. Lancet 1992; 339: 943–946, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Setamou M., Cardwell K. F., Schulthess F., Hell K. Aspergillus flavus infection and aflatoxin contamination of preharvest maize in Benin. Plant Dis. 1997; 81: 1323–1327
   PubMed Web of Science ®Google Scholar
• Setamou M., Cardwell K. F., Schulthess F., Hell K. Effect of insect damage to maize ears, with special reference to Mussidia nigrivenella on Aspergillus flavus infection and aflatoxin production in maize before harvest in the Republic of Benin. J. Econ. Entomol. 1998; 91: 433–438
   Web of Science ®Google Scholar
• Shank R. C., Gordon J. E., Wogan G. N., Nondasuta A., Subhamani B. Dietary aflatoxins and human liver cancer. III. Field survey of rural Thai families for ingested aflatoxins. Food Cosmet. Toxicol. 1972; 10: 501–507, [CROSSREF]
   PubMedGoogle Scholar
• Silvotti L., Petterino C., Bonomi A., Cabassi E. Immunotoxicological effects of maternal aflatoxin exposure in weaned piglets. Vet. Rec. 1997; 141: 469–472, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Turner P. C., Mendy M., Whittle H., Fortuin M., Hall A. J., Wild C. P. Hepatitis B infection and aflatoxin biomarker levels in Gambian children. Trop. Med. Int. Health 2000; 5: 837–841, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Turner P. C., Moore S. E., Hall A. J., Prentice A. M., Wild C. P. Modification of immune function through exposure to dietary aflatoxin in Gambian children. Environ. Health Perspect. 2003; 111(2)217–220, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Udoh J. M., Ikotun I. O., Cardwell K. F. Storage structures and aflatoxin content of maize in five agroecological zones of Nigeria. J. Stored Prod. Res. 2000; 36: 187–201, [CROSSREF]
   Web of Science ®Google Scholar
• Van Rensburg S. J., Cook Mozaffari P., Van Schalkwyk D. J., Van der Watt J. J., Vincent T. J. Purchase IF hepatocellular carcinoma and dietary aflatoxin in Mozambique and Transkei. Br. J. Cancer 1985; 51: 713–726, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Whitaker T. B., Dickens J. W., Monroe R. J. Variability associated with testing corn for aflatoxin. J. Am. Oil Chem. Soc. 1979; 56: 789–794
   Web of Science ®Google Scholar
• Wicklow D. T. Preharvest origins of toxigenic fungi in stored grain. Proceedings of 6th International Working Conference on Stored‐Product Protection, E. Highley, E. J. Wright, H. J. Banks, B. R. Champ. CAB International, CanberraAustralia 1994; 1075–1081, 1273
   Google Scholar
• Wild C. P., Hall A. J. Epidemiology of mycotoxin‐related disease. The Mycota VI Human and Animal Relationships, Howard, Miller, 1996; 213–225
   Google Scholar
• Wild C. P., Jiang Y. Z., Sabbioni G., Chapot B., Montesano R. Evaluation of methods for quantitation of aflatoxin‐albumin adducts and their application to human exposure assessment. Cancer Res. 1990; 50: 245–251, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Wild C. P., Hudson G. J., Sabbiono G., Chapot B., Hall A. J., Wogan G. N., Whittle H., Montesano R., Groopman J. D. Dietary intake of aflatoxins and the level of albumin‐bound aflatoxin in peripheral blood in the Gambia, West Africa. Cancer Epidemiol. Biomark. Prev. 1992; 1: 234–299
   Web of Science ®Google Scholar
• Wood G. E. Aflatoxins in domestic and imported foods and feeds. J. Assoc. Off. Anal. Chem. 1989; 72: 543, [PUBMED], [INFOTRIEVE]
   PubMedGoogle Scholar
• Wood G. E. Mycotoxins in foods and their safety ramifications. Food Safety Assessment, J. W. Finley, S. F. Robinson, D. J. Armstrong. ACS Symposium Series, American Chemical Society, Washington, DC 1992a; Vol. 484: 261
   Google Scholar
• Wood G. E. Mycotoxins in foods and feeds in the United States. J. Anim. Sci. 1992b; 70: 3941, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Wood G. E., Trucksess M. W. Regulatory control programs for mycotoxin‐contaminated food. Mycotoxins in Agriculture and Food Safety, Sinha, Bhatnagar. Marcel Dekker, New York 1998; 459–481
   Google Scholar
• Yuan J. M., Ross R. K., Stanczyk F. Z., Govindaragan S., Gao Y.‐T. A cohort study of serum testosterone and hepatocellular carcinoma in Shanghai, China. Int. J. Cancer 1995; 6: 4493–4991
   Google Scholar