The Variable Transmembrane Domain of Drosophila N-Cadherin Regulates Adhesive Activity

REFERENCES

• Brieher, W. M., A. S. Yap, and B. M. Gumbiner. 1996. Lateral dimerization is required for the homophilic binding activity of C-cadherin. J. Cell Biol. 135:487–496.
   PubMed Web of Science ®Google Scholar
• Broadbent, I. D., and J. Pettitt. 2002. The C. elegans hmr-1 gene can encode a neuronal classic cadherin involved in the regulation of axon fasciculation. Curr. Biol. 12:59–63.
   PubMedGoogle Scholar
• Chitaev, N. A., and S. M. Troyanovsky. 1998. Adhesive but not lateral E-cadherin complexes require calcium and catenins for their formation. J. Cell Biol. 142:837–846.
   PubMed Web of Science ®Google Scholar
• Curran, A. R., and D. M. Engelman. 2003. Sequence motifs, polar interactions and conformational changes in helical membrane proteins. Curr. Opin. Struct. Biol. 13:412–417.
   PubMed Web of Science ®Google Scholar
• Duguay, D., R. A. Foty, and M. S. Steinberg. 2003. Cadherin-mediated cell adhesion and tissue segregation: qualitative and quantitative determinants. Dev. Biol. 253:309–323.
   PubMed Web of Science ®Google Scholar
• Esumi, S., N. Kakazu, Y. Taguchi, T. Hirayama, A. Sasaki, T. Hirabayashi, T. Koide, T. Kitsukawa, S. Hamada, and T. Yagi. 2005. Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons. Nat. Genet. 37:171–176.
   PubMed Web of Science ®Google Scholar
• Gumbiner, B. M. 1996. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84:345–357.
   PubMed Web of Science ®Google Scholar
• Hamada, S., and T. Yagi. 2001. The cadherin-related neuronal receptor family: a novel diversified cadherin family at the synapse. Neurosci. Res. 41:207–215.
   PubMedGoogle Scholar
• Heid, C. A., J. Stevens, K. J. Livak, and P. M. Williams. 1996. Real time quantitative PCR. Genome Res. 6:986–994.
   PubMed Web of Science ®Google Scholar
• Hummel, T., and S. L. Zipursky. 2004. Afferent induction of olfactory glomeruli requires N-cadherin. Neuron 42:77–88.
   PubMedGoogle Scholar
• Iwai, Y., Y. Hirota, K. Ozaki, H. Okano, M. Takeichi, and T. Uemura. 2002. DN-cadherin is required for spatial arrangement ultrastructural organization of synapses. Mol. Cell Neurosci. 19:375–388.
   PubMed Web of Science ®Google Scholar
• Iwai, Y., T. Usui, S. Hirano, R. Steward, M. Takeichi, and T. Uemura. 1997. Axon patterning requires DN-cadherin, a novel neuronal adhesion receptor, in the Drosophila embryonic CNS. Neuron 19:77–89.
   PubMed Web of Science ®Google Scholar
• Larrivee, D. C. 1979. A biochemical analysis of the Drosophila rhabdomere and its extracellular environment. Ph.D. dissertation. Purdue University, West Lafayette, Ind.
   Google Scholar
• Lee, C. H., T. Herman, T. R. Clandinin, R. Lee, and S. L. Zipursky. 2001. N-cadherin regulates target specificity in the Drosophila visual system. Neuron 30:437–450.
   PubMedGoogle Scholar
• Mendrola, J. M., M. B. Berger, M. C. King, and M. A. Lemmon. 2002. The single transmembrane domains of ErbB receptors self-associate in cell membranes. J. Biol. Chem. 277:4704–4712.
   PubMed Web of Science ®Google Scholar
• Missler, M., and T. C. Sudhof. 1998. Neurexins: three genes and 1001 products. Trends Genet. 14:20–26.
   PubMedGoogle Scholar
• Moyer, W. A., and M. S. Steinberg. 1976. Do rates of intercellular adhesion measure the cell affinities reflected in cell-sorting and tissue-spreading configurations? Dev. Biol. 52:246–262.
   PubMed Web of Science ®Google Scholar
• Murray, M. J., D. J. Merritt, A. H. Brand, and P. M. Whitington. 1998. In vivo dynamics of axon pathfinding in the Drosophilia CNS: a time-lapse study of an identified motorneuron. J. Neurobiol. 37:607–621.
   PubMedGoogle Scholar
• Nern, A., L. V. Nguyen, T. Herman, S. Prakash, T. R. Clandinin, and S. L. Zipursky. 2005. An isoform-specific allele of Drosophila N-cadherin disrupts a late step of R7 targeting. Proc. Natl. Acad. Sci. USA 102:12944–12949.
   PubMed Web of Science ®Google Scholar
• Neves, G., J. Zucker, M. Daly, and A. Chess. 2004. Stochastic yet biased expression of multiple Dscam splice variants by individual cells. Nat. Genet. 36:240–246.
   PubMed Web of Science ®Google Scholar
• Oda, H., K. Tagawa, and Y. Akiyama-Oda. 2005. Diversification of epithelial adherens junctions with independent reductive changes in cadherin form: identification of potential molecular synapomorphies among bilaterians. Evol. Dev. 7:376–389.
   PubMedGoogle Scholar
• Oda, H., T. Uemura, Y. Harada, Y. Iwai, and M. Takeichi. 1994. A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell-cell adhesion. Dev. Biol. 165:716–726.
   PubMed Web of Science ®Google Scholar
• Ozawa, M. 26 March 2002. Lateral dimerization of the E-cadherin extracellular domain is necessary but not sufficient for adhesive activity. J. Biol. Chem. 277:19600–19608. [Epub ahead of print.]
   PubMed Web of Science ®Google Scholar
• Pacquelet, A., L. Lin, and P. Rorth. 2003. Binding site for p120/delta-catenin is not required for Drosophila E-cadherin function in vivo. J. Cell Biol. 160:313–319.
   PubMed Web of Science ®Google Scholar
• Prakash, S., J. C. Caldwell, D. F. Eberl, and T. R. Clandinin. 2005. Drosophila N-cadherin mediates an attractive interaction between photoreceptor axons and their targets. Nat. Neurosci. 8:443–450.
   PubMed Web of Science ®Google Scholar
• Radhakrishna, R. C. 1965. Linear statistical inference and its applications. John Wiley & Sons Inc, New York, N.Y.
   Google Scholar
• Ritzenthaler, S., E. Suzuki, and A. Chiba. 2000. Postsynaptic filopodia in muscle cells interact with innervating motoneuron axons. Nat. Neurosci. 3:1012–1017.
   PubMed Web of Science ®Google Scholar
• Russ, W. P., and D. M. Engelman. 2000. The GxxxG motif: a framework for transmembrane helix-helix association. J. Mol. Biol. 296:911–919.
   PubMed Web of Science ®Google Scholar
• Schmucker, D., J. C. Clemens, H. Shu, C. A. Worby, J. Xiao, M. Muda, J. E. Dixon, and S. L. Zipursky. 2000. Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell 101:671–684.
   PubMed Web of Science ®Google Scholar
• Schmucker, D., and J. G. Flanagan. 2004. Generation of recognition diversity in the nervous system. Neuron 44:219–222.
   PubMedGoogle Scholar
• Shapiro, L., and D. R. Colman. 1999. The diversity of cadherins and implications for a synaptic adhesive code in the CNS. Neuron 23:427–430.
   PubMed Web of Science ®Google Scholar
• Tabuchi, K., and T. C. Sudhof. 2002. Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing. Genomics 79:849–859.
   PubMedGoogle Scholar
• Takeda, H., Y. Shimoyama, A. Nagafuchi, and S. Hirohashi. 1999. E-cadherin functions as a cis-dimer at the cell-cell adhesive interface in vivo. Nat. Struct. Biol. 6:310–312.
   PubMedGoogle Scholar
• Takeichi, M. 1991. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251:1451–1455.
   PubMed Web of Science ®Google Scholar
• Tanabe, K., M. Takeichi, and S. Nakagawa. 2004. Identification of a nonchordate-type classic cadherin in vertebrates: chicken Hz-cadherin is expressed in horizontal cells of the neural retina and contains a nonchordate-specific domain complex. Dev. Dyn. 229:899–906.
   PubMedGoogle Scholar
• Tanaka, H., W. Shan, G. R. Phillips, K. Arndt, O. Bozdagi, L. Shapiro, G. W. Huntley, D. L. Benson, and D. R. Colman. 2000. Molecular modification of N-cadherin in response to synaptic activity. Neuron 25:93–107.
   PubMed Web of Science ®Google Scholar
• Ting, C. Y., S. Yonekura, P. Chung, S. N. Hsu, H. M. Robertson, A. Chiba, and C. H. Lee. 2005. Drosophila N-cadherin functions in the first stage of the two-stage layer-selection process of R7 photoreceptor afferents. Development 132:953–963.
   PubMed Web of Science ®Google Scholar
• Troyanovsky, R. B., E. Sokolov, and S. M. Troyanovsky. 2003. Adhesive and lateral E-cadherin dimers are mediated by the same interface. Mol. Cell. Biol. 23:7965–7972.
   PubMed Web of Science ®Google Scholar
• Ullrich, B., Y. A. Ushkaryov, and T. C. Sudhof. 1995. Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons. Neuron 14:497–507.
   PubMed Web of Science ®Google Scholar
• van der Meer, J. M., and L. F. Jaffe. 1983. Elemental composition of the perivitelline fluid in early Drosophila embryos. Dev. Biol. 95:249–252.
   PubMedGoogle Scholar
• Vasenkova, I., D. Luginbuhl, and A. Chiba. 2006. Gliopodia extend the range of direct glia-neuron communication during the CNS development in Drosophila. Mol. Cell. Neurosci. 31:123–130.
   PubMed Web of Science ®Google Scholar
• Wang, J., X. Ma, J. S. Yang, X. Zheng, C. T. Zugates, C. H. Lee, and T. Lee. 2004. Transmembrane/juxtamembrane domain-dependent Dscam distribution and function during mushroom body neuronal morphogenesis. Neuron 43:663–672.
   PubMedGoogle Scholar
• Wilson, I. A., and L. K. Jolliffe. 1999. The structure, organization, activation and plasticity of the erythropoietin receptor. Curr. Opin. Struct. Biol. 9:696–704.
   PubMed Web of Science ®Google Scholar
• Wojtowicz, W. M., J. J. Flanagan, S. S. Millard, S. L. Zipursky, and J. C. Clemens. 2004. Alternative splicing of Drosophila Dscam generates axon guidance receptors that exhibit isoform-specific homophilic binding. Cell 118:619–633.
   PubMedGoogle Scholar
• Wu, Q., and T. Maniatis. 1999. A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 97:779–790.
   PubMed Web of Science ®Google Scholar
• Yagi, T., and M. Takeichi. 2000. Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. Genes Dev. 14:1169–1180.
   PubMed Web of Science ®Google Scholar
• Zhan, X. L., J. C. Clemens, G. Neves, D. Hattori, J. J. Flanagan, T. Hummel, M. L. Vasconcelos, A. Chess, and S. L. Zipursky. 2004. Analysis of Dscam diversity in regulating axon guidance in Drosophila mushroom bodies. Neuron 43:673–686.
   PubMedGoogle Scholar
• Zhu, H., and L. Luo. 2004. Diverse functions of N-cadherin in dendritic and axonal terminal arborization of olfactory projection neurons. Neuron 42:63–75.
   PubMedGoogle Scholar