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Article

The Winged Helix Transcription Factor Foxa3 Regulates Adipocyte Differentiation and Depot-Selective Fat Tissue Expansion

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Pages 3392-3399 | Received 05 Mar 2013, Accepted 31 May 2013, Published online: 20 Mar 2023

REFERENCES

  • Anghel SI, Wahli W. 2007. Fat poetry: a kingdom for PPAR gamma. Cell Res. 17:486–511.
  • Farmer SR. 2006. Transcriptional control of adipocyte formation. Cell Metab. 4:263–273.
  • Scherer PE. 2006. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes 55:1537–1545.
  • Wajchenberg BL. 2000. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr. Rev. 21:697–738.
  • Tontonoz P, Hu E, Spiegelman BM. 1994. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell 79:1147–1156.
  • Cristancho AG, Lazar MA. 2011. Forming functional fat: a growing understanding of adipocyte differentiation. Nat. Rev. Mol. Cell Biol. 12:722–734.
  • Hannenhalli S, Kaestner KH. 2009. The evolution of Fox genes and their role in development and disease. Nat. Rev. Genet. 10:233–240.
  • Sund NJ, Ang SL, Sackett SD, Shen W, Daigle N, Magnuson MA, Kaestner KH. 2000. Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte. Mol. Cell. Biol. 20:5175–5183.
  • Lee CS, Friedman JR, Fulmer JT, Kaestner KH. 2005. The initiation of liver development is dependent on Foxa transcription factors. Nature 435:944–947.
  • Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH. 2008. Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev. 22:3435–3448.
  • Nakae J, Kitamura T, Kitamura Y, Biggs WHIII, Arden KC, Accili D. 2003. The forkhead transcription factor Foxo1 regulates adipocyte differentiation. Dev. Cell 4:119–129.
  • Wolfrum C, Shih DQ, Kuwajima S, Norris AW, Kahn CR, Stoffel M. 2003. Role of Foxa-2 in adipocyte metabolism and differentiation. J. Clin. Invest. 112:345–356.
  • Davis KE, Moldes M, Farmer SR. 2004. The forkhead transcription factor FoxC2 inhibits white adipocyte differentiation. J. Biol. Chem. 279:42453–42461.
  • Friedman JR, Kaestner KH. 2006. The Foxa family of transcription factors in development and metabolism. Cell. Mol. Life Sci. 63:2317–2328.
  • Meruvu S, Hugendubler L, Mueller E. 2011. Regulation of adipocyte differentiation by the zinc finger protein ZNF638. J. Biol. Chem. 286:26516–26523.
  • Liu A, McLaughlin T, Liu T, Sherman A, Yee G, Abbasi F, Lamendola C, Morton J, Cushman SW, Reaven GM, Tsao PS. 2009. Differential intra-abdominal adipose tissue profiling in obese, insulin-resistant women. Obes. Surg. 19:1564–1573.
  • Kaestner KH, Hiemisch H, Schutz G. 1998. Targeted disruption of the gene encoding hepatocyte nuclear factor 3gamma results in reduced transcription of hepatocyte-specific genes. Mol. Cell. Biol. 18:4245–4251.
  • Shen W, Scearce LM, Brestelli JE, Sund NJ, Kaestner KH. 2001. Foxa3 (hepatocyte nuclear factor 3gamma) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast. J. Biol. Chem. 276:42812–42817.

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