Casein Kinase 1 Delta Regulates the Pace of the Mammalian Circadian Clock

REFERENCES

• Agostino, P. V., S. A. Plano, and D. A. Golombek. 2008. 2008. Circadian and pharmacological regulation of casein kinase I in the hamster suprachiasmatic nucleus. J. Genet. 87:467–471.
   PubMed Web of Science ®Google Scholar
• Akashi, M., Y. Tsuchiya, T. Yoshino, and E. Nishida. 2002. Control of intracellular dynamics of mammalian period proteins by casein kinase I ε (CKIε) and CKIδ in cultured cells. Mol. Cell. Biol. 22:1693–1703.
   PubMed Web of Science ®Google Scholar
• Badura, L., T. Swanson, W. Adamowicz, J. Adams, J. Cianfrogna, K. Fisher, J. Holland, R. Kleiman, F. Nelson, L. Reynolds, K. St Germain, E. Schaeffer, B. Tate, and J. Sprouse. 2007. An inhibitor of casein kinase I epsilon induces phase delays in circadian rhythms under free-running and entrained conditions. J. Pharmacol. Exp. Ther. 322:730–738.
   PubMed Web of Science ®Google Scholar
• Balsalobre, A., F. Damiola, and U. Schibler. 1998. A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 93:929–937.
   PubMed Web of Science ®Google Scholar
• Blau, J. 2008. PERspectives on PER phosphorylation. Genes Dev. 22:1737–1740.
   PubMedGoogle Scholar
• Busino, L., F. Bassermann, A. Maiolica, C. Lee, P. M. Nolan, S. I. Godinho, G. F. Draetta, and M. Pagano. 2007. SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science 316:900–904.
   PubMed Web of Science ®Google Scholar
• Camacho, F., M. Cilio, Y. Guo, D. M. Virshup, K. Patel, O. Khorkova, S. Styren, B. Morse, Z. Yao, and G. A. Keesler. 2001. Human casein kinase Iδ phosphorylation of human circadian clock proteins period 1 and 2. FEBS Lett. 489:159–165.
   PubMed Web of Science ®Google Scholar
• Chiu, J. C., J. T. Vanselow, A. Kramer, and I. Edery. 2008. The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock. Genes Dev. 22:1758–1772.
   PubMedGoogle Scholar
• DeBruyne, J. P., E. Noton, C. M. Lambert, E. S. Maywood, D. R. Weaver, and S. M. Reppert. 2006. A clock shock: mouse CLOCK is not required for circadian oscillator function. Neuron 50:465–477.
   PubMed Web of Science ®Google Scholar
• DeBruyne, J. P., D. R. Weaver, and S. M. Reppert. 2007. Peripheral circadian oscillators require CLOCK. Curr. Biol. 17:R538–539.
   PubMed Web of Science ®Google Scholar
• Eide, E. J., E. L. Vielhaber, W. A. Hinz, and D. M. Virshup. 2002. The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase I epsilon. J. Biol. Chem. 277:17248–17254.
   PubMed Web of Science ®Google Scholar
• Eide, E. J., M. F. Woolf, H. Kang, P. Woolf, W. Hurst, F. Camacho, E. L. Vielhaber, A. Giovanni, and D. M. Virshup. 2005. Control of mammalian circadian rhythm by CKIε-regulated proteasome-mediated PER2 degradation. Mol. Cell. Biol. 25:2795–2807.
   PubMed Web of Science ®Google Scholar
• Fan, J. Y., F. Preuss, M. J. Muskus, E. S. Bjes, and J. L. Price. 2009. Drosophila and vertebrate casein kinase Iδ exhibits evolutionary conservation of circadian function. Genetics 181:139–152.
   PubMedGoogle Scholar
• Gallego, M., E. J. Eide, M. F. Woolf, D. M. Virshup, and D. B. Forger. 2006. An opposite role for tau in circadian rhythms revealed by mathematical modeling. Proc. Natl. Acad. Sci. USA 103:10618–10623.
   PubMed Web of Science ®Google Scholar
• Gatfield, D., and U. Schibler. 2007. Proteasome keeps the circadian clock ticking. Science 316:1135–1136.
   PubMedGoogle Scholar
• Godinho, S. I., E. S. Maywood, L. Shaw, V. Tucci, A. R. Barnard, L. Busino, M. Pagano, R. Kendall, M. M. Quwailid, M. R. Romero, J. O'Neill, J. E. Chesham, D. Brooker, Z. Lalanne, M. H. Hastings, and P. M. Nolan. 2007. The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period. Science 316:897–900.
   PubMed Web of Science ®Google Scholar
• Graves, P. R., and P. J. Roach. 1995. Role of COOH-terminal phosphorylation in the regulation of casein kinase I delta. J. Biol. Chem. 270:21689–21694.
   PubMedGoogle Scholar
• Izumo, M., C. H. Johnson, and S. Yamazaki. 2003. Circadian gene expression in mammalian fibroblasts revealed by real-time luminescence reporting: temperature compensation and damping. Proc. Natl. Acad. Sci. USA 100:16089–16094.
   PubMed Web of Science ®Google Scholar
• Knippschild, U., A. Gocht, S. Wolff, N. Huber, J. Lohlker, and M. Stoter. 2005. The casein kinase 1 family: participation in multiple cellular processes in eukaryotes. Cell Signal. 15:675–689.
   Google Scholar
• Kornmann, B., O. Schaad, H. Bujard, J. S. Takahashi, and U. Schibler. 2007. System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock. PLoS Biol. 5:e34.
   PubMed Web of Science ®Google Scholar
• Lee, C., J. P. Etchegaray, F. R. Cagampang, A. S. Loudon, and S. M. Reppert. 2001. Posttranslational mechanisms regulate the mammalian circadian clock. Cell 107:855–867.
   PubMed Web of Science ®Google Scholar
• Lee, C., D. R. Weaver, and S. M. Reppert. 2004. Direct association between mouse PERIOD and CKIε is critical for a functioning circadian clock. Mol. Cell. Biol. 24:584–594.
   PubMed Web of Science ®Google Scholar
• Lowrey, P. L., K. Shimomura, M. P. Antoch, S. Yamazaki, P. D. Zemenides, M. R. Ralph, M. Menaker, and J. S. Takahashi. 2000. Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science 288:483–492.
   PubMed Web of Science ®Google Scholar
• Meng, Q. J., L. Logunova, E. S. Maywood, M. Gallego, J. Lebiecki, T. M. Brown, M. Sladek, A. S. Semikhodskii, N. R. Glossop, H. D. Piggins, J. E. Chesham, D. A. Bechtold, S. H. Yoo, J. S. Takahashi, D. M. Virschup, R. P. Boot-Handford, M. H. Hastings, and A. S. Loudon. 2008. Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins. Neuron 58:78–88.
   PubMed Web of Science ®Google Scholar
• Numano, R., S. Yamazaki, N. Umeda, T. Samura, M. Sujino, R. Takahashi, M. Ueda, A. Mori, K. Yamada, Y. Sakaki, S.-I. T. Inouye, M. Menaker, and H. Tei. 2006. Constitutive expression of the period 1 gene impairs behavioral and molecular circadian rhythms. Proc. Natl. Acad. Sci. USA 103:3716–3721.
   PubMed Web of Science ®Google Scholar
• Postic, C., M. Shiota, K. D. Niswender, T. L. Jetton, Y. Chen, J. M. Moates, K. D. Shelton, J. Lindner, A. D. Cherrington, and M. A. Magnuson. 1999. Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knockouts using Cre recombinase. J. Biol. Chem. 274:305–315.
   PubMed Web of Science ®Google Scholar
• Reischl, S., K. Vanselow, P. O. Westermark, N. Thierfelder, B. Maier, H. Herzel, and A. Kramer. 2007. Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics. J. Biol. Rhythms 22:375–386.
   PubMed Web of Science ®Google Scholar
• Sekine, T., T. Yamaguchi, K. Hamano, M. W. Young, M. Shimoda, and L. Saez. 2008. Casein kinase I epsilon does not rescue double-time function in Drosophila despite evolutionarily conserved roles in the circadian clock. J. Biol. Rhythms 23:3–15.
   PubMed Web of Science ®Google Scholar
• Shirogane, T., J. Jin, X. L. Ang, and J. W. Harper. 2005. SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein. J. Biol. Chem. 280:26863–26872.
   PubMed Web of Science ®Google Scholar
• Siepka, S. M., S. H. Yoo, J. Park, W. Song, V. Kumar, Y. Hu, C. Lee, and J. S. Takahashi. 2007. Circadian mutant Overtime reveals F-box protein FBXL3 regulation of Cryptochrome and Period gene expression. Cell 129:1011–1023.
   PubMed Web of Science ®Google Scholar
• Stratmann, M., and U. Schibler. 2006. Properties, entrainment, and physiological functions of mammalian peripheral oscillators. J. Biol. Rhythms 21:494–506.
   PubMed Web of Science ®Google Scholar
• Takahashi, J. S., H.K Hong, C. H. Ko, and E. L. McDearmon. 2008. The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nat. Rev. Genet. 9:764–775.
   PubMed Web of Science ®Google Scholar
• Toh, K. L., C. R. Jones, Y. He, E. J. Eide, W. A. Hinz, D. M. Virshup, L. J. Ptacek, and Y. H. Fu. 2001. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science 291:1040–1043.
   PubMed Web of Science ®Google Scholar
• Vanselow, K., J. T. Vanselow, P. O. Westermark, S. Reischl, B. Maier, T. Korte, A. Herrmann, H. Herzel, A. Schlosser, and A. Kramer. 2006. Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS). Genes Dev. 20:2660–2672.
   PubMed Web of Science ®Google Scholar
• Vielhaber, E., E. Eide, A. Rivers, Z. H. Gao, and D. M. Virshup. 2000. Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon. Mol. Cell. Biol. 20:4888–4899.
   PubMed Web of Science ®Google Scholar
• Weaver, D. R., and S. M. Reppert. 2008. Circadian timekeeping, p. 931-957. In L. R. Squire, D. Berg, F. E. Bloom, S. du Lacv, A. Ghosh, and N. C. Spitzer (ed.), Fundamental neuroscience, 3rd ed. Academic Press, Inc., New York, NY.
   Google Scholar
• Welsh, D. K., S. H. Yoo, A. C. Liu, J. S. Takahashi, and S. A. Kay. 2004. Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Curr. Biol. 14:2289–2295.
   PubMed Web of Science ®Google Scholar
• Xu, Y., Q. S. Padiath, R. E. Shapiro, C. R. Jones, S. C. Wu, N. Saigoh, K. Saigoh, L. J. Ptacek, and Y. H. Fu. 2005. Functional consequences of a CKIδ mutation causing familial advanced sleep phase syndrome. Nature 434:640–644.
   PubMed Web of Science ®Google Scholar
• Xu, Y., K. L. Toh, C. R. Jones, J. Y. Shin, Y. H. Fu, and L. J. Ptacek. 2007. Modeling of a human circadian mutation yields insights into clock regulation by PER2. Cell 128:59–70.
   PubMed Web of Science ®Google Scholar
• Yamazaki, S., and J. S. Takahashi. 2005. Real-time luminescence reporting of circadian gene expression in mammals. Methods Enzymol. 393:288–301.
   PubMed Web of Science ®Google Scholar
• Yoo, S. H., S. Yamazaki, P. L. Lowrey, K. Shimomura, C. H. Ko, E. D. Buhr, S. M. Siepka, H. K. Hong, W. J. Oh, O. J. Yoo, M. Menaker, and J. S. Takahashi. 2004. PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc. Natl. Acad. Sci. USA 101:5339–5346.
   PubMed Web of Science ®Google Scholar