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Article

Regulation of Linear Ubiquitin Chain Assembly Complex by Caspase-Mediated Cleavage of RNF31

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Pages 3010-3018 | Received 23 Aug 2016, Accepted 19 Sep 2016, Published online: 17 Mar 2023

REFERENCES

  • Oeckinghaus A, Ghosh S. 2009. The NF-κB family of transcription factors and its regulation. Cold Spring Harb Perspect Biol 1:a000034. http://dx.doi.org/10.1101/cshperspect.a000034.
  • Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD. 2006. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation [corrected]. Nat Cell Biol 8:398–406. http://dx.doi.org/10.1038/ncb1384.
  • Ikeda F, Deribe YL, Skanland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJ, Goswami P, Nagy V, Terzic J, Tokunaga F, Androulidaki A, Nakagawa T, Pasparakis M, Iwai K, Sundberg JP, Schaefer L, Rittinger K, Macek B, Dikic I. 2011. SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Nature 471:637–641. http://dx.doi.org/10.1038/nature09814.
  • Tokunaga F, Nakagawa T, Nakahara M, Saeki Y, Taniguchi M, Sakata S, Tanaka K, Nakano H, Iwai K. 2011. SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex. Nature 471:633–636. http://dx.doi.org/10.1038/nature09815.
  • Gerlach B, Cordier SM, Schmukle AC, Emmerich CH, Rieser E, Haas TL, Webb AI, Rickard JA, Anderton H, Wong WW, Nachbur U, Gangoda L, Warnken U, Purcell AW, Silke J, Walczak H. 2011. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 471:591–596. http://dx.doi.org/10.1038/nature09816.
  • Iwai K, Fujita H, Sasaki Y. 2014. Linear ubiquitin chains: NF-κB signalling, cell death and beyond. Nat Rev Mol Cell Biol 15:503–508. http://dx.doi.org/10.1038/nrm3836.
  • Strasser A, O'Connor L, Dixit VM. 2000. Apoptosis signaling. Annu Rev Biochem 69:217–245. http://dx.doi.org/10.1146/annurev.biochem.69.1.217.
  • Karin M, Lin A. 2002. NF-κB at the crossroads of life and death. Nat Immunol 3:221–227. http://dx.doi.org/10.1038/ni0302-221.
  • Frelin C, Imbert V, Bottero V, Gonthier N, Samraj AK, Schulze-Osthoff K, Auberger P, Courtois G, Peyron JF. 2008. Inhibition of the NF-κB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-κB essential modulator NEMO. Cell Death Differ 15:152–160. http://dx.doi.org/10.1038/sj.cdd.4402240.
  • Lin Y, Devin A, Rodriguez Y, Liu ZG. 1999. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 13:2514–2526. http://dx.doi.org/10.1101/gad.13.19.2514.
  • Ravi R, Bedi A, Fuchs EJ, Bedi A. 1998. CD95 (Fas)-induced caspase-mediated proteolysis of NF-κB. Cancer Res 58:882–886.
  • Crawford ED, Wells JA. 2011. Caspase substrates and cellular remodeling. Annu Rev Biochem 80:1055–1087. http://dx.doi.org/10.1146/annurev-biochem-061809-121639.
  • Song J, Tan H, Shen H, Mahmood K, Boyd SE, Webb GI, Akutsu T, Whisstock JC. 2010. Cascleave: towards more accurate prediction of caspase substrate cleavage sites. Bioinformatics 26:752–760. http://dx.doi.org/10.1093/bioinformatics/btq043.
  • Emmerich CH, Ordureau A, Strickson S, Arthur JS, Pedrioli PG, Komander D, Cohen P. 2013. Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains. Proc Natl Acad Sci U S A 110:15247–15252. http://dx.doi.org/10.1073/pnas.1314715110.
  • Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S, Yamamoto M, Akira S, Takao T, Tanaka K, Iwai K. 2009. Involvement of linear polyubiquitylation of NEMO in NF-κB activation. Nat Cell Biol 11:123–132. http://dx.doi.org/10.1038/ncb1821.
  • Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. 2014. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 343:84–87. http://dx.doi.org/10.1126/science.1247005.
  • Mackay C, Carroll E, Ibrahim AF, Garg A, Inman GJ, Hay RT, Alpi AF. 2014. E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin. Cancer Res 74:2246–2257. http://dx.doi.org/10.1158/0008-5472.CAN-13-2131.
  • Fujita H, Rahighi S, Akita M, Kato R, Sasaki Y, Wakatsuki S, Iwai K. 2014. Mechanism underlying IκB kinase activation mediated by the linear ubiquitin chain assembly complex. Mol Cell Biol 34:1322–1335. http://dx.doi.org/10.1128/MCB.01538-13.
  • Damgaard RB, Walker JA, Marco-Casanova P, Morgan NV, Titheradge HL, Elliott PR, McHale D, Maher ER, McKenzie AN, Komander D. 2016. The deubiquitinase OTULIN is an essential negative regulator of inflammation and autoimmunity. Cell 166:1215–1230.e20. http://dx.doi.org/10.1016/j.cell.2016.07.019.
  • Park Y, Jin HS, Lopez J, Lee J, Liao L, Elly C, Liu YC. 2016. SHARPIN controls regulatory T cells by negatively modulating the T cell antigen receptor complex. Nat Immunol 17:286–296. http://dx.doi.org/10.1038/ni.3352.
  • Shimizu Y, Taraborrelli L, Walczak H. 2015. Linear ubiquitination in immunity. Immunol Rev 266:190–207. http://dx.doi.org/10.1111/imr.12309.
  • Elliott PR, Komander D. 2016. Regulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULIN. FEBS J 283:39–53. http://dx.doi.org/10.1111/febs.13547.
  • Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai WL, Kuehn HS, Wang H, Yang D, Park YH, Ombrello AK, Blake M, Romeo T, Remmers EF, Chae JJ, Mullikin JC, Guzel F, Milner JD, Boehm M, Rosenzweig SD, Gadina M, Welch SB, Ozen S, Topaloglu R, Abinun M, Kastner DL, Aksentijevich I. 2016. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. Proc Natl Acad Sci U S A 113:10127–10132. http://dx.doi.org/10.1073/pnas.1612594113.
  • Nakanishi C, Toi M. 2005. Nuclear factor-κB inhibitors as sensitizers to anticancer drugs. Nat Rev Cancer 5:297–309. http://dx.doi.org/10.1038/nrc1588.
  • Niu J, Shi Y, Iwai K, Wu ZH. 2011. LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO. EMBO J 30:3741–3753. http://dx.doi.org/10.1038/emboj.2011.264.

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