Splice-Mediated Motif Switching Regulates Disabled-1 Phosphorylation and SH2 Domain Interactions

REFERENCES

• Ballif BA, et al. 2004. Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr. Biol. 14:606–610.
   PubMed Web of Science ®Google Scholar
• Ballif BA, Arnaud L, Cooper JA. 2003. Tyrosine phosphorylation of Disabled-1 is essential for Reelin-stimulated activation of Akt and Src family kinases. Brain Res. Mol. Brain Res. 117:152–159.
   PubMedGoogle Scholar
• Bar I, Tissir F, Lambert de Rouvroit C, De Backer O, Goffinet AM. 2003. The gene encoding disabled-1 (DAB1), the intracellular adaptor of the Reelin pathway, reveals unusual complexity in human and mouse. J. Biol. Chem. 278:5802–5812.
   PubMedGoogle Scholar
• Barnes AP, et al. 2007. LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell 129:549–563.
   PubMed Web of Science ®Google Scholar
• Blencowe BJ. 2006. Alternative splicing: new insights from global analyses. Cell 126:37–47.
   PubMed Web of Science ®Google Scholar
• Bock HH, Herz J. 2003. Reelin activates SRC family tyrosine kinases in neurons. Curr. Biol. 13:18–26.
   PubMed Web of Science ®Google Scholar
• Bock HH, et al. 2003. Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination. J. Biol. Chem. 278:38772–38779.
   PubMed Web of Science ®Google Scholar
• Chen K, et al. 2004. Interaction between Dab1 and CrkII is promoted by Reelin signaling. J. Cell Sci. 117:4527–4536.
   PubMedGoogle Scholar
• Colwill K, et al. 2011. A roadmap to generate renewable protein binders to the human proteome. Nat. Methods 8:551–558.
   PubMed Web of Science ®Google Scholar
• Costagli A, Felice B, Guffanti A, Wilson SW, Mione M. 2006. Identification of alternatively spliced Dab1 isoforms in zebrafish. Dev. Genes Evol. 216:291–299.
   PubMedGoogle Scholar
• D'Arcangelo G, et al. 1995. A protein related to extracellular matrix proteins deleted in the mouse mutant reeler. Nature 374:719–723.
   PubMed Web of Science ®Google Scholar
• Dierck K, Machida K, Mayer BJ, Nollau P. 2009. Profiling the tyrosine phosphorylation state using SH2 domains. Methods Mol. Biol. 527:131–155, ix.
   PubMedGoogle Scholar
• Feng L, Allen NS, Simo S, Cooper JA. 2007. Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development. Genes Dev. 21:2717–2730.
   PubMedGoogle Scholar
• Feng L, Cooper JA. 2009. Dual functions of Dab1 during brain development. Mol. Cell. Biol. 29:324–332.
   PubMedGoogle Scholar
• Franco SJ, Martinez-Garay I, Gil-Sanz C, Harkins-Perry SR, Muller U. 2011. Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex. Neuron 69:482–497.
   PubMed Web of Science ®Google Scholar
• Gao Z, Godbout R. 2011. Serine phosphorylation regulates disabled-1 early isoform turnover independently of Reelin. Cell Signal. 23:555–565.
   PubMedGoogle Scholar
• Gao Z, Monckton EA, Glubrecht DD, Logan C, Godbout R. 2010. The early isoform of disabled-1 functions independently of Reelin-mediated tyrosine phosphorylation in chick retina. Mol. Cell. Biol. 30:4339–4353.
   PubMedGoogle Scholar
• Gupta A, Tsai LH, Wynshaw-Boris A. 2002. Life is a journey: a genetic look at neocortical development. Nat. Rev. Genet. 3:342–355.
   PubMed Web of Science ®Google Scholar
• Herz J, Chen Y. 2006. Reelin, lipoprotein receptors and synaptic plasticity. Nat. Rev. Neurosci. 7:850–859.
   PubMed Web of Science ®Google Scholar
• Howell BW, Gertler FB, Cooper JA. 1997. Mouse disabled (mDab1): a Src binding protein implicated in neuronal development. EMBO J. 16:121–132.
   PubMed Web of Science ®Google Scholar
• Howell BW, Herrick TM, Cooper JA. 1999. Reelin-induced tyrosine phosphorylation of disabled 1 during neuronal positioning. Genes Dev. 13:643–648.
   PubMed Web of Science ®Google Scholar
• Howell BW, Herrick TM, Hildebrand JD, Zhang Y, Cooper JA. 2000. Dab1 tyrosine phosphorylation sites relay positional signals during mouse brain development. Curr. Biol. 10:877–885.
   PubMedGoogle Scholar
• Howell BW, Lanier LM, Frank R, Gertler FB, Cooper JA. 1999. The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids. Mol. Cell. Biol. 19:5179–5188.
   PubMedGoogle Scholar
• Huang Y, et al. 2004. Tyrosine phosphorylated Disabled 1 recruits Crk family adapter proteins. Biochem. Biophys. Res. Commun. 318:204–212.
   PubMed Web of Science ®Google Scholar
• Jones-Villeneuve EM, Rudnicki MA, Harris JF, McBurney MW. 1983. Retinoic acid-induced neural differentiation of embryonal carcinoma cells. Mol. Cell. Biol. 3:2271–2279.
   PubMed Web of Science ®Google Scholar
• Jossin Y, Cooper JA. 2011. Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex. Nat. Neurosci. 14:697–703.
   PubMed Web of Science ®Google Scholar
• Katyal S, Gao Z, Monckton E, Glubrecht D, Godbout R. 2007. Hierarchical disabled-1 tyrosine phosphorylation in Src family kinase activation and neurite formation. J. Mol. Biol. 368:349–364.
   PubMedGoogle Scholar
• Katyal S, Glubrecht DD, Li L, Gao Z, Godbout R. 2011. Disabled-1 alternative splicing in human fetal retina and neural tumors. PLoS One 6:e28579.
   PubMedGoogle Scholar
• Katyal S, Godbout R. 2004. Alternative splicing modulates Disabled-1 (Dab1) function in the developing chick retina. EMBO J. 23:1878–1888.
   PubMedGoogle Scholar
• Liu BA, et al. 2010. SH2 domains recognize contextual peptide sequence information to determine selectivity. Mol. Cell. Proteomics 9:2391–2404.
   PubMed Web of Science ®Google Scholar
• Long H, et al. 2011. Identification of alternatively spliced Dab1 and Fyn isoforms in pig. BMC Neurosci. 12:17.
   PubMedGoogle Scholar
• Machida K, Mayer BJ. 2009. Detection of protein-protein interactions by far-western blotting. Methods Mol. Biol. 536:313–329.
   PubMedGoogle Scholar
• Matsuki T, et al. 2010. Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment. Cell 143:826–836.
   PubMed Web of Science ®Google Scholar
• Mayer BJ, Hirai H, Sakai R. 1995. Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases. Curr. Biol. 5:296–305.
   PubMed Web of Science ®Google Scholar
• Niu S, Renfro A, Quattrocchi CC, Sheldon M, D'Arcangelo G. 2004. Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway. Neuron 41:71–84.
   PubMed Web of Science ®Google Scholar
• Nollau P, Mayer BJ. 2001. Profiling the global tyrosine phosphorylation state by Src homology 2 domain binding. Proc. Natl. Acad. Sci. U. S. A. 98:13531–13536.
   PubMedGoogle Scholar
• Pramatarova A, et al. 2003. Nck beta interacts with tyrosine-phosphorylated disabled 1 and redistributes in Reelin-stimulated neurons. Mol. Cell. Biol. 23:7210–7221.
   PubMedGoogle Scholar
• Rice DS, Curran T. 2001. Role of the reelin signaling pathway in central nervous system development. Annu. Rev. Neurosci. 24:1005–1039.
   PubMed Web of Science ®Google Scholar
• Rivera GM, et al. 2006. Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B. Proc. Natl. Acad. Sci. U. S. A. 103:9536–9541.
   PubMedGoogle Scholar
• Sheldon M, et al. 1997. scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice. Nature 389:730–733.
   PubMed Web of Science ®Google Scholar
• Simo S, Jossin Y, Cooper JA. 2010. Cullin 5 regulates cortical layering by modulating the speed and duration of Dab1-dependent neuronal migration. J. Neurosci. 30:5668–5676.
   PubMedGoogle Scholar
• Songyang Z, et al. 1993. SH2 domains recognize specific phosphopeptide sequences. Cell 72:767–778.
   PubMed Web of Science ®Google Scholar
• Tremblay RG, et al. 2010. Differentiation of mouse Neuro 2A cells into dopamine neurons. J. Neurosci. Methods 186:60–67.
   PubMed Web of Science ®Google Scholar
• Trommsdorff M, Borg JP, Margolis B, Herz J. 1998. Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein. J. Biol. Chem. 273:33556–33560.
   PubMed Web of Science ®Google Scholar
• Trommsdorff M, et al. 1999. Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell 97:689–701.
   PubMed Web of Science ®Google Scholar
• Yano M, Hayakawa-Yano Y, Mele A, Darnell RB. 2010. Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Neuron 66:848–858.
   PubMed Web of Science ®Google Scholar