The L7Ae RNA Binding Motif Is a Multifunctional Domain Required for the Ribosome-Dependent Sec Incorporation Activity of Sec Insertion Sequence Binding Protein 2

REFERENCES

• Allmang, C., P. Carbon, and A. Krol. 2002. The SBP2 and 15.5 kD/Snu13p proteins share the same RNA binding domain: identification of SBP2 amino acids important to SECIS RNA binding. RNA 8:1308–1318.
   PubMedGoogle Scholar
• Ban, N., P. Nissen, J. Hansen, P. B. Moore, and T. A. Steitz. 2000. The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science 289:905–920.
   PubMed Web of Science ®Google Scholar
• Chao, J. A., and J. R. Williamson. 2004. Joint X-ray and NMR refinement of the yeast L30e-mRNA complex. Structure 12:1165–1176.
   PubMed Web of Science ®Google Scholar
• Chavatte, L., B. A. Brown, and D. M. Driscoll. 2005. Ribosomal protein L30 is a component of the UGA-selenocysteine recoding machinery in eukaryotes. Nat. Struct. Mol. Biol. 12:408–416.
   PubMedGoogle Scholar
• Chou, M. Y., N. Rooke, C. W. Turck, and D. L. Black. 1999. hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells. Mol. Cell. Biol. 19:69–77.
   PubMed Web of Science ®Google Scholar
• Copeland, P. R., and D. M. Driscoll. 1999. Purification, redox sensitivity, and RNA binding properties of SECIS-binding protein 2, a protein involved in selenoprotein biosynthesis. J. Biol. Chem. 274:25447–25454.
   PubMedGoogle Scholar
• Copeland, P. R., J. E. Fletcher, B. A. Carlson, D. L. Hatfield, and D. M. Driscoll. 2000. A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs. EMBO J. 19:306–314.
   PubMed Web of Science ®Google Scholar
• Copeland, P. R., V. A. Stepanik, and D. M. Driscoll. 2001. Insight into mammalian selenocysteine insertion: domain structure and ribosome binding properties of Sec insertion sequence binding protein 2. Mol. Cell. Biol. 21:1491–1498.
   PubMedGoogle Scholar
• Fagegaltier, D., N. Hubert, K. Yamada, T. Mizutani, P. Carbon, and A. Krol. 2000. Characterization of mSelB, a novel mammalian elongation factor for selenoprotein translation. EMBO J. 19:4796–4805.
   PubMed Web of Science ®Google Scholar
• Gamberi, C., E. Izaurralde, C. Beisel, and I. W. Mattaj. 1997. Interaction between the human nuclear cap-binding protein complex and hnRNP F. Mol. Cell. Biol. 17:2587–2597.
   PubMed Web of Science ®Google Scholar
• Halic, M., T. Becker, J. Frank, C. M. Spahn, and R. Beckmann. 2005. Localization and dynamic behavior of ribosomal protein L30e. Nat. Struct. Mol. Biol. 12:467–468.
   PubMedGoogle Scholar
• Hamma, T., and A. R. Ferre-D'Amare. 2004. Structure of protein L7Ae bound to a K-turn derived from an archaeal box H/ACA sRNA at 1.8 A resolution. Structure 12:893–903.
   PubMedGoogle Scholar
• Handy, D. E., G. Hang, J. Scolaro, N. Metes, N. Razaq, Y. Yang, and J. Loscalzo. 2006. Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation. J. Biol. Chem. 281:3382–3388.
   PubMedGoogle Scholar
• Jemiolo, D. K., F. T. Pagel, and E. J. Murgola. 1995. UGA suppression by a mutant RNA of the large ribosomal subunit. Proc. Natl. Acad. Sci. USA 92:12309–12313.
   PubMedGoogle Scholar
• Kinzy, S. A., K. Caban, and P. R. Copeland. 2005. Characterization of the SECIS binding protein 2 complex required for the co-translational insertion of selenocysteine in mammals. Nucleic Acids Res. 33:5172–5180.
   PubMedGoogle Scholar
• Klein, D. J., T. M. Schmeing, P. B. Moore, and T. A. Steitz. 2001. The kink-turn: a new RNA secondary structure motif. EMBO J. 20:4214–4221.
   PubMed Web of Science ®Google Scholar
• Koonin, E. V., P. Bork, and C. Sander. 1994. A novel RNA-binding motif in omnipotent suppressors of translation termination, ribosomal proteins and a ribosome modification enzyme? Nucleic Acids Res. 22:2166–2167.
   PubMedGoogle Scholar
• Lee, B. J., M. Rajagopalan, Y. S. Kim, K. H. You, K. B. Jacobson, and D. Hatfield. 1990. Selenocysteine tRNA[Ser]Sec gene is ubiquitous within the animal kingdom. Mol. Cell. Biol. 10:1940–1949.
   PubMed Web of Science ®Google Scholar
• Manuvakhova, M., K. Keeling, and D. M. Bedwell. 2000. Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system. RNA 6:1044–1055.
   PubMed Web of Science ®Google Scholar
• Martin, G. W., III, J. W. Harney, and M. J. Berry. 1996. Selenocysteine incorporation in eukaryotes: insights into mechanism and efficiency from sequence, structure, and spacing proximity studies of the type 1 deiodinase SECIS element. RNA 2:171–182.
   PubMed Web of Science ®Google Scholar
• Matunis, M. J., J. Xing, and G. Dreyfuss. 1994. The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. Nucleic Acids Res. 22:1059–1067.
   PubMedGoogle Scholar
• Mehta, A., C. M. Rebsch, S. A. Kinzy, J. E. Fletcher, and P. R. Copeland. 2004. Efficiency of mammalian selenocysteine incorporation. J. Biol. Chem. 279:37852–37859.
   PubMed Web of Science ®Google Scholar
• Papp, L. V., J. Lu, F. Striebel, D. Kennedy, A. Holmgren, and K. K. Khanna. 2006. The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Mol. Cell. Biol. 26:4895–4910.
   PubMedGoogle Scholar
• Razga, F., N. Spackova, K. Reblova, J. Koca, N. B. Leontis, and J. Sponer. 2004. Ribosomal RNA kink-turn motif: a flexible molecular hinge. J. Biomol. Struct. Dyn. 22:183–194.
   PubMed Web of Science ®Google Scholar
• Razga, F., M. Zacharias, K. Reblova, J. Koca, and J. Sponer. 2006. RNA kink-turns as molecular elbows: hydration, cation binding, and large-scale dynamics. Structure 14:825–835.
   PubMedGoogle Scholar
• Rost, B., G. Yachdav, and J. Liu. 2004. The PredictProtein server. Nucleic Acids Res. 32:W321–W326.
   PubMed Web of Science ®Google Scholar
• Salas-Marco, J., and D. M. Bedwell. 2005. Discrimination between defects in elongation fidelity and termination efficiency provides mechanistic insights into translational readthrough. J. Mol. Biol. 348:801–815.
   PubMed Web of Science ®Google Scholar
• Suryadi, J., E. J. Tran, E. S. Maxwell, and B. A. Brown II. 2005. The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs. Biochemistry 44:9657–9672.
   PubMedGoogle Scholar
• Reference deleted.
   Google Scholar
• Tujebajeva, R. M., P. R. Copeland, X. M. Xu, B. A. Carlson, J. W. Harney, D. M. Driscoll, D. L. Hatfield, and M. J. Berry. 2000. Decoding apparatus for eukaryotic selenocysteine insertion. EMBO Rep. 1:158–163.
   PubMed Web of Science ®Google Scholar
• Valente, L., and T. G. Kinzy. 2003. Yeast as a sensor of factors affecting the accuracy of protein synthesis. Cell. Mol. Life Sci. 60:2115–2130.
   PubMedGoogle Scholar
• Vidovic, I., S. Nottrott, K. Hartmuth, R. Luhrmann, and R. Ficner. 2000. Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment. Mol. Cell 6:1331–1342.
   PubMedGoogle Scholar