Interactions of Brf1 Peptides with the Tetratricopeptide Repeat-Containing Subunit of TFIIIC Inhibit and Promote Preinitiation Complex Assembly

REFERENCES

• Brun, I., A. Sentenac, and M. Werner. 1997. Dual role of the C34 subunit of RNA polymerase III in transcription initiation. EMBO J. 16:5730–5741.
   PubMed Web of Science ®Google Scholar
• Bushnell, D. A., K. D. Westover, R. E. Davis, and R. D. Kornberg. 2004. Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 angstroms. Science 303:983–988.
   PubMed Web of Science ®Google Scholar
• Chaussivert, N., C. Conesa, S. Shaaban, and A. Sentenac. 1995. Complex interactions between yeast TFIIIB and TFIIIC. J. Biol. Chem. 270:15353–15358.
   PubMedGoogle Scholar
• Cliff, M. J., R. Harris, D. Barford, J. E. Ladbury, and M. A. Williams. 2006. Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90. Structure 14:415–426.
   PubMedGoogle Scholar
• Cloutier, T. E., M. D. Librizzi, A. K. Mollah, M. Brenowitz, and I. M. Willis. 2001. Kinetic trapping of DNA by transcription factor IIIB. Proc. Natl. Acad. Sci. USA 98:9581–9586.
   PubMedGoogle Scholar
• Colbert, T., S. Lee, G. Schimmack, and S. Hahn. 1998. Architecture of protein and DNA contacts within the TFIIIB-DNA complex. Mol. Cell. Biol. 18:1682–1691.
   PubMed Web of Science ®Google Scholar
• D'Andrea, L. D., and L. Regan. 2003. TPR proteins: the versatile helix. Trends Biochem. Sci. 28:655–662.
   PubMed Web of Science ®Google Scholar
• Dumay-Odelot, H., J. Acker, R. Arrebola, A. Sentenac, and C. Marck. 2002. Multiple roles of the τ131 subunit of yeast transcription factor IIIC (TFIIIC) in TFIIIB assembly. Mol. Cell. Biol. 22:298–308.
   PubMedGoogle Scholar
• Ferri, M. L., G. Peyroche, M. Siaut, O. Lefebvre, C. Carles, C. Conesa, and A. Sentenac. 2000. A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70. Mol. Cell. Biol. 20:488–495.
   PubMedGoogle Scholar
• Gatto, G. J., Jr., B. V. Geisbrecht, S. J. Gould, and J. M. Berg. 2000. Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5. Nat. Struct. Biol. 7:1091–1095.
   PubMedGoogle Scholar
• Geiduschek, E. P., and G. A. Kassavetis. 2001. The RNA polymerase III transcription apparatus. J. Mol. Biol. 310:1–26.
   PubMed Web of Science ®Google Scholar
• Huet, J., C. Conesa, C. Carles, and A. Sentenac. 1997. A cryptic DNA binding domain at the COOH terminus of TFIIIB70 affects formation, stability, and function of preinitiation complexes. J. Biol. Chem. 272:18341–18349.
   PubMedGoogle Scholar
• Juo, Z. S., G. A. Kassavetis, J. Wang, E. P. Geiduschek, and P. B. Sigler. 2003. Crystal structure of a transcription factor IIIB core interface ternary complex. Nature 422:534–539.
   PubMed Web of Science ®Google Scholar
• Kassavetis, G. A., B. Bartholomew, J. A. Blanco, T. E. Johnson, and E. P. Geiduschek. 1991. Two essential components of the Saccharomyces cerevisiae transcription factor TFIIIB: transcription and DNA-binding properties. Proc. Natl. Acad. Sci. USA 88:7308–7312.
   PubMedGoogle Scholar
• Kassavetis, G. A., B. R. Braun, L. H. Nguyen, and E. P. Geiduschek. 1990. S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors. Cell 60:235–245.
   PubMed Web of Science ®Google Scholar
• Kassavetis, G. A., R. Driscoll, and E. P. Geiduschek. 2006. Mapping the principal interaction site of the Brf1 and Bdp1 subunits of Saccharomyces cerevisiae TFIIIB. J. Biol. Chem. 281:14321–14329.
   PubMedGoogle Scholar
• Kassavetis, G. A., A. Kumar, E. Ramirez, and E. P. Geiduschek. 1998. Functional and structural organization of Brf, the TFIIB-related component of the RNA polymerase III transcription initiation complex. Mol. Cell. Biol. 18:5587–5599.
   PubMedGoogle Scholar
• Kassavetis, G. A., G. A. Letts, and E. P. Geiduschek. 2001. The RNA polymerase III transcription initiation factor TFIIIB participates in two steps of promoter opening. EMBO J. 20:2823–2834.
   PubMed Web of Science ®Google Scholar
• Kassavetis, G. A., E. Soragni, R. Driscoll, and E. P. Geiduschek. 2005. Reconfiguring the connectivity of a multiprotein complex: fusions of yeast TATA-binding protein with Brf1, and the function of transcription factor IIIB. Proc. Natl. Acad. Sci. USA 102:15406–15411.
   PubMedGoogle Scholar
• Khoo, B., B. Brophy, and S. P. Jackson. 1994. Conserved functional domains of the RNA polymerase III general transcription factor BRF. Genes Dev. 8:2879–2890.
   PubMed Web of Science ®Google Scholar
• Kumar, A., A. Grove, G. A. Kassavetis, and E. P. Geiduschek. 1998. Transcription factor IIIB: the architecture of its DNA complex, and its roles in initiation of transcription by RNA polymerase III. Cold Spring Harbor Symp. Quant. Biol. 63:121–129.
   PubMedGoogle Scholar
• Lapouge, K., S. J. Smith, P. A. Walker, S. J. Gamblin, S. J. Smerdon, and K. Rittinger. 2000. Structure of the TPR domain of p67phox in complex with Rac. GTP. Mol. Cell 6:899–907.
   PubMed Web of Science ®Google Scholar
• Liao, Y., I. M. Willis, and R. D. Moir. 2003. The Brf1 and Bdp1 subunits of transcription factor TFIIIB bind to overlapping sites in the tetratricopeptide repeats of Tfc4. J. Biol. Chem. 278:44467–44474.
   PubMedGoogle Scholar
• Librizzi, M. D., R. D. Moir, M. Brenowitz, and I. M. Willis. 1996. Expression and purification of the RNA polymerase III transcription specificity factor IIIB70 from Saccharomyces cerevisiae and its cooperative binding with TATA-binding protein. J. Biol. Chem. 271:32695–32701.
   PubMedGoogle Scholar
• Moir, R. D., K. V. Puglia, and I. M. Willis. 2002. A gain-of-function mutation in the second tetratricopeptide repeat of TFIIIC131 relieves autoinhibition of Brf1 binding. Mol. Cell. Biol. 22:6131–6141.
   PubMedGoogle Scholar
• Moir, R. D., K. V. Puglia, and I. M. Willis. 2002. Autoinhibition of TFIIIB70 binding by the tetratricopeptide repeat-containing subunit of TFIIIC. J. Biol. Chem. 277:694–701.
   PubMedGoogle Scholar
• Moir, R. D., I. Sethy-Coraci, K. Puglia, M. D. Librizzi, and I. M. Willis. 1997. A tetratricopeptide repeat mutation in yeast transcription factor IIIC131 (TFIIIC131) facilitates recruitment of TFIIB-related factor TFIIIB70. Mol. Cell. Biol. 17:7119–7125.
   PubMedGoogle Scholar
• Moir, R. D., and I. M. Willis. 2004. Tetratricopeptide repeats of Tfc4 and a limiting step in the assembly of the initiation factor TFIIIB. Adv. Protein Chem. 67:93–121.
   PubMedGoogle Scholar
• Nikolov, D. B., H. Chen, E. D. Halay, A. A. Usheva, K. Hisatake, D. K. Lee, R. G. Roeder, and S. K. Burley. 1995. Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature 377:119–128.
   PubMed Web of Science ®Google Scholar
• Rai, B. K., and A. Fiser. 2006. Multiple mapping method: a novel approach to the sequence-to-structure alignment problem in comparative protein structure modeling. Proteins 63:644–661.
   PubMedGoogle Scholar
• Scheufler, C., A. Brinker, G. Bourenkov, S. Pegoraro, L. Moroder, H. Bartunik, F. U. Hartl, and I. Moarefi. 2000. Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. Cell 101:199–210.
   PubMed Web of Science ®Google Scholar
• Schramm, L., and N. Hernandez. 2002. Recruitment of RNA polymerase III to its target promoters. Genes Dev. 16:2593–2620.
   PubMed Web of Science ®Google Scholar
• Sethy-Coraci, I., R. D. Moir, A. Lopez-de-Leon, and I. M. Willis. 1998. A differential response of wild type and mutant promoters to TFIIIB70 overexpression in vivo and in vitro. Nucleic Acids Res. 26:2344–2352.
   PubMedGoogle Scholar
• Staudinger, J., M. Perry, S. J. Elledge, and E. N. Olson. 1993. Interactions among vertebrate helix-loop-helix proteins in yeast using the two-hybrid system. J. Biol. Chem. 268:4608–4611.
   PubMedGoogle Scholar
• Werner, M., N. Chaussivert, I. M. Willis, and A. Sentenac. 1993. Interaction between a complex of RNA polymerase III subunits and the 70-kDa component of transcription factor IIIB. J. Biol. Chem. 268:20721–20724.
   PubMed Web of Science ®Google Scholar
• Wu, B., P. Li, Y. Liu, Z. Lou, Y. Ding, C. Shu, S. Ye, M. Bartlam, B. Shen, and Z. Rao. 2004. 3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex. Proc. Natl. Acad. Sci. USA 101:8348–8353.
   PubMed Web of Science ®Google Scholar
• Yang, M., Z. Wu, and S. Fields. 1995. Protein-peptide interactions analyzed with the yeast two-hybrid system. Nucleic Acids Res. 23:1152–1156.
   PubMedGoogle Scholar