CPEB4 Is a Cell Survival Protein Retained in the Nucleus upon Ischemia or Endoplasmic Reticulum Calcium Depletion

REFERENCES

• Alarcon, J. M., R. Hodgman, M. Theis, Y. S. Huang, E. R. Kandel, and J. D. Richter. 2004. Selective modulation of some forms of Schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene. Learn. Mem. 11:318–327.
   PubMed Web of Science ®Google Scholar
• Banker, G., and K. Goslin. 1988. Developments in neuronal cell culture. Nature 336:185–186.
   PubMedGoogle Scholar
• Berger-Sweeney, J., N. R. Zearfoss, and J. D. Richter. 2006. Reduced extinction of hippocampal-dependent memories in CPEB knockout mice. Learn. Mem. 13:4–7.
   PubMed Web of Science ®Google Scholar
• Cao, G., R. S. Clark, W. Pei, W. Yin, F. Zhang, F. Y. Sun, S. H. Graham, and J. Chen. 2003. Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation. J. Cereb. Blood Flow Metab. 23:1137–1150.
   PubMed Web of Science ®Google Scholar
• Choi, D. W., and S. M. Rothman. 1990. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu. Rev. Neurosci. 13:171–182.
   PubMed Web of Science ®Google Scholar
• Corpet, F. 1988. Multiple sequence alignment with hierarchical clustering. Nucleic Acids Res. 16:10881–10890.
   PubMed Web of Science ®Google Scholar
• Daugas, E., S. A. Susin, N. Zamzami, K. F. Ferri, T. Irinopoulou, N. Larochette, M. C. Prevost, B. Leber, D. Andrews, J. Penninger, and G. Kroemer. 2000. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J. 14:729–739.
   PubMed Web of Science ®Google Scholar
• Demaurex, N., and M. Frieden. 2003. Measurements of the free luminal ER Ca(2+) concentration with targeted “cameleon” fluorescent proteins. Cell Calcium 34:109–119.
   PubMedGoogle Scholar
• Du, L., and J. D. Richter. 2005. Activity-dependent polyadenylation in neurons. RNA 11:1340–1347.
   PubMedGoogle Scholar
• Emptage, N., T. V. Bliss, and A. Fine. 1999. Single synaptic events evoke NMDA receptor-mediated release of calcium from internal stores in hippocampal dendritic spines. Neuron 22:115–124.
   PubMed Web of Science ®Google Scholar
• Ferrari, F., V. Mercaldo, G. Piccoli, C. Sala, S. Cannata, T. Achsel, and C. Bagni. 2007. The fragile X mental retardation protein-RNP granules show an mGluR-dependent localization in the post-synaptic spines. Mol. Cell Neurosci. 34:343–354.
   PubMed Web of Science ®Google Scholar
• Feske, S., Y. Gwack, M. Prakriya, S. Srikanth, S. H. Puppel, B. Tanasa, P. G. Hogan, R. S. Lewis, M. Daly, and A. Rao. 2006. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441:179–185.
   PubMed Web of Science ®Google Scholar
• Frandsen, A., and A. Schousboe. 1992. Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons. Proc. Natl. Acad. Sci. U. S. A. 89:2590–2594.
   PubMedGoogle Scholar
• Hofmann, I., M. Schnolzer, I. Kaufmann, and W. W. Franke. 2002. Symplekin, a constitutive protein of karyo- and cytoplasmic particles involved in mRNA biogenesis in Xenopus laevis oocytes. Mol. Biol. Cell 13:1665–1676.
   PubMedGoogle Scholar
• Hu, B. R., M. E. Martone, Y. Z. Jones, and C. L. Liu. 2000. Protein aggregation after transient cerebral ischemia. J. Neurosci. 20:3191–3199.
   PubMed Web of Science ®Google Scholar
• Huang, Y. S., J. H. Carson, E. Barbarese, and J. D. Richter. 2003. Facilitation of dendritic mRNA transport by CPEB. Genes Dev. 17:638–653.
   PubMedGoogle Scholar
• Huang, Y. S., M. C. Kan, C. L. Lin, and J. D. Richter. 2006. CPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNA. EMBO J. 25:4865–4876.
   PubMed Web of Science ®Google Scholar
• Hudmon, A., and H. Schulman. 2002. Neuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function. Annu. Rev. Biochem. 71:473–510.
   PubMed Web of Science ®Google Scholar
• Ishida, A., Y. Shigeri, Y. Tatsu, K. Uegaki, I. Kameshita, S. Okuno, T. Kitani, N. Yumoto, and H. Fujisawa. 1998. Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin-dependent protein kinase II. FEBS Lett. 427:115–118.
   PubMedGoogle Scholar
• Jousset, H., M. Frieden, and N. Demaurex. 2007. STIM1 knockdown reveals that store-operated Ca2+ channels located close to sarco/endoplasmic Ca2+ ATPases (SERCA) pumps silently refill the endoplasmic reticulum. J. Biol. Chem. 282:11456–11464.
   PubMed Web of Science ®Google Scholar
• Kudo, N., N. Matsumori, H. Taoka, D. Fujiwara, E. P. Schreiner, B. Wolff, M. Yoshida, and S. Horinouchi. 1999. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc. Natl. Acad. Sci. U. S. A. 96:9112–9117.
   PubMed Web of Science ®Google Scholar
• Lin, C. L., V. Evans, S. Shen, Y. Xing, and J. D. Richter. 2010. The nuclear experience of CPEB: implications for RNA processing and translational control. RNA 16:338–348.
   PubMed Web of Science ®Google Scholar
• Luik, R. M., M. M. Wu, J. Buchanan, and R. S. Lewis. 2006. The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions. J. Cell Biol. 174:815–825.
   PubMed Web of Science ®Google Scholar
• Macchi, P., A. M. Brownawell, B. Grunewald, L. DesGroseillers, I. G. Macara, and M. A. Kiebler. 2004. The brain-specific double-stranded RNA-binding protein Staufen2: nucleolar accumulation and isoform-specific exportin-5-dependent export. J. Biol. Chem. 279:31440–31444.
   PubMedGoogle Scholar
• Mandel, C. R., S. Kaneko, H. Zhang, D. Gebauer, V. Vethantham, J. L. Manley, and L. Tong. 2006. Polyadenylation factor CPSF-73 is the pre-mRNA 3′-end-processing endonuclease. Nature 444:953–956.
   PubMed Web of Science ®Google Scholar
• Mercer, J. C., W. I. Dehaven, J. T. Smyth, B. Wedel, R. R. Boyles, G. S. Bird, and J. W. Putney, Jr. 2006. Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J. Biol. Chem. 281:24979–24990.
   PubMed Web of Science ®Google Scholar
• Morimoto, N., Y. Oida, M. Shimazawa, M. Miura, T. Kudo, K. Imaizumi, and H. Hara. 2007. Involvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice. Neuroscience 147:957–967.
   PubMed Web of Science ®Google Scholar
• Niimura, M., N. Takagi, K. Takagi, R. Mizutani, N. Ishihara, K. Matsumoto, H. Funakoshi, T. Nakamura, and S. Takeo. 2006. Prevention of apoptosis-inducing factor translocation is a possible mechanism for protective effects of hepatocyte growth factor against neuronal cell death in the hippocampus after transient forebrain ischemia. J. Cereb. Blood Flow Metab. 26:1354–1365.
   PubMed Web of Science ®Google Scholar
• Nishi, K., M. Yoshida, D. Fujiwara, M. Nishikawa, S. Horinouchi, and T. Beppu. 1994. Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. J. Biol. Chem. 269:6320–6324.
   PubMed Web of Science ®Google Scholar
• Palmer, A. E., C. Jin, J. C. Reed, and R. Y. Tsien. 2004. Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc. Natl. Acad. Sci. U. S. A. 101:17404–17409.
   PubMed Web of Science ®Google Scholar
• Paschen, W., S. Hotop, and C. Aufenberg. 2003. Loading neurons with BAPTA-AM activates xbp1 processing indicative of induction of endoplasmic reticulum stress. Cell Calcium 33:83–89.
   PubMedGoogle Scholar
• Peinelt, C., M. Vig, D. L. Koomoa, A. Beck, M. J. Nadler, M. Koblan-Huberson, A. Lis, A. Fleig, R. Penner, and J. P. Kinet. 2006. Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nat. Cell Biol. 8:771–773.
   PubMed Web of Science ®Google Scholar
• Petosa, C., G. Schoehn, P. Askjaer, U. Bauer, M. Moulin, U. Steuerwald, M. Soler-Lopez, F. Baudin, I. W. Mattaj, and C. W. Muller. 2004. Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex. Mol. Cell 16:761–775.
   PubMedGoogle Scholar
• Plesnila, N., C. Zhu, C. Culmsee, M. Groger, M. A. Moskowitz, and K. Blomgren. 2004. Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 24:458–466.
   PubMed Web of Science ®Google Scholar
• Plum, F. 1983. What causes infarction in ischemic brain? The Robert Wartenberg Lecture. Neurology 33:222–233.
   PubMed Web of Science ®Google Scholar
• Prakriya, M., S. Feske, Y. Gwack, S. Srikanth, A. Rao, and P. G. Hogan. 2006. Orai1 is an essential pore subunit of the CRAC channel. Nature 443:230–233.
   PubMed Web of Science ®Google Scholar
• Richter, J. D. 2007. CPEB: a life in translation. Trends Biochem. Sci. 32:279–285.
   PubMed Web of Science ®Google Scholar
• Roos, J., P. J. DiGregorio, A. V. Yeromin, K. Ohlsen, M. Lioudyno, S. Zhang, O. Safrina, J. A. Kozak, S. L. Wagner, M. D. Cahalan, G. Velicelebi, and K. A. Stauderman. 2005. STIM1, an essential and conserved component of store-operated Ca2+ channel function. J. Cell Biol. 169:435–445.
   PubMed Web of Science ®Google Scholar
• Rose, C. R., and A. Konnerth. 2001. Stores not just for storage. Intracellular calcium release and synaptic plasticity. Neuron 31:519–522.
   PubMed Web of Science ®Google Scholar
• Rossi, D. J., T. Oshima, and D. Attwell. 2000. Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature 403:316–321.
   PubMed Web of Science ®Google Scholar
• Steward, O., C. S. Wallace, G. L. Lyford, and P. F. Worley. 1998. Synaptic activation causes the mRNA for the IEG arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 21:741–751.
   PubMed Web of Science ®Google Scholar
• Susin, S. A., H. K. Lorenzo, N. Zamzami, I. Marzo, B. E. Snow, G. M. Brothers, J. Mangion, E. Jacotot, P. Costantini, M. Loeffler, N. Larochette, D. R. Goodlett, R. Aebersold, D. P. Siderovski, J. M. Penninger, and G. Kroemer. 1999. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397:441–446.
   PubMed Web of Science ®Google Scholar
• Svoboda, K., and Z. F. Mainen. 1999. Synaptic [Ca2+]: intracellular stores spill their guts. Neuron 22:427–430.
   PubMedGoogle Scholar
• Tay, J., and J. D. Richter. 2001. Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice. Dev. Cell 1:201–213.
   PubMedGoogle Scholar
• Tymianski, M., M. P. Charlton, P. L. Carlen, and C. H. Tator. 1993. Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J. Neurosci. 13:2085–2104.
   PubMed Web of Science ®Google Scholar
• Tymianski, M., M. C. Wallace, I. Spigelman, M. Uno, P. L. Carlen, C. H. Tator, and M. P. Charlton. 1993. Cell-permeant Ca2+ chelators reduce early excitotoxic and ischemic neuronal injury in vitro and in vivo. Neuron 11:221–235.
   PubMed Web of Science ®Google Scholar
• van Leyen, K., H. Y. Kim, S. R. Lee, G. Jin, K. Arai, and E. H. Lo. 2006. Baicalein and 12/15-lipoxygenase in the ischemic brain. Stroke 37:3014–3018.
   PubMed Web of Science ®Google Scholar
• Watterson, D. M., S. Mirzoeva, L. Guo, A. Whyte, J. J. Bourguignon, M. Hibert, J. Haiech, and L. J. Van Eldik. 2001. Ligand modulation of glial activation: cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1 beta and nitric oxide synthase II. Neurochem. Int. 39:459–468.
   PubMedGoogle Scholar
• Wells, D. G., X. Dong, E. M. Quinlan, Y. S. Huang, M. F. Bear, J. D. Richter, and J. R. Fallon. 2001. A role for the cytoplasmic polyadenylation element in NMDA receptor-regulated mRNA translation in neurons. J. Neurosci. 21:9541–9548.
   PubMedGoogle Scholar
• Wu, L., D. Wells, J. Tay, D. Mendis, M. A. Abbott, A. Barnitt, E. Quinlan, A. Heynen, J. R. Fallon, and J. D. Richter. 1998. CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses. Neuron 21:1129–1139.
   PubMedGoogle Scholar
• Zearfoss, N. R., J. M. Alarcon, P. Trifilieff, E. Kandel, and J. D. Richter. 2008. A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus. J. Neurosci. 28:8502–8509.
   PubMed Web of Science ®Google Scholar
• Zhang, S. L., Y. Yu, J. Roos, J. A. Kozak, T. J. Deerinck, M. H. Ellisman, K. A. Stauderman, and M. D. Cahalan. 2005. STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane. Nature 437:902–905.
   PubMed Web of Science ®Google Scholar
• Zhao, H., M. A. Yenari, D. Cheng, O. L. Barreto-Chang, R. M. Sapolsky, and G. K. Steinberg. 2004. Bcl-2 transfection via herpes simplex virus blocks apoptosis-inducing factor translocation after focal ischemia in the rat. J. Cereb. Blood Flow Metab. 24:681–692.
   PubMed Web of Science ®Google Scholar
• Zhu, C., L. Qiu, X. Wang, U. Hallin, C. Cande, G. Kroemer, H. Hagberg, and K. Blomgren. 2003. Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain. J. Neurochem. 86:306–317.
   PubMed Web of Science ®Google Scholar