Acetylation-Dependent Interaction of SATB1 and CtBP1 Mediates Transcriptional Repression by SATB1

REFERENCES

• Alvarez, J. D., D. H. Yasui, H. Niida, T. Joh, D. Y. Loh, and T. K. Shigematsu. 2000. The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. Genes Dev. 14:521–535.
   PubMed Web of Science ®Google Scholar
• Andersson, K. B., E. Kowenz-Leutz, E. M. Brendeford, A. H. Tygsett, A. Leutz, and O. S. Gabrielsen. 2003. Phosphorylation-dependent down-regulation of c-Myb DNA binding is abrogated by a point mutation in the v-myb oncogene. J. Biol. Chem. 278:3816–3824.
   PubMedGoogle Scholar
• Baert, J. L., C. Beaudoin, L. Coutte, and Y. de Launoit. 2002. ERM transactivation is up-regulated by the repression of DNA binding after the PKA phosphorylation of a consensus site at the edge of the ETS domain. J. Biol. Chem. 277:1002–1012.
   PubMed Web of Science ®Google Scholar
• Barolo, S., T. Stone, A. G. Bang, and J. W. Posakony. 2002. Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless. Genes Dev. 16:1964–1976.
   PubMedGoogle Scholar
• Bonizzi, G., and M. Karin. 2004. The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 25:280–288.
   PubMed Web of Science ®Google Scholar
• Boyd, J. M., T. Subramanian, U. Schaeper, M. La Regina, S. Bayley, and G. Chinnadurai. 1993. A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis. EMBO J. 12:469–478.
   PubMed Web of Science ®Google Scholar
• Boyes, J., P. Byfield, Y. Nakatani, and V. Ogryzko. 1998. Regulation of activity of the transcription factor GATA-1 by acetylation. Nature 396:594–598.
   PubMed Web of Science ®Google Scholar
• Brannon, M., J. D. Brown, R. Bates, D. Kimelman, and R. T. Moon. 1999. X CtBP is a XTcf-3 co-repressor with roles throughout Xenopus development. Development 126:3159–3170.
   PubMed Web of Science ®Google Scholar
• Cai, S., H. J. Han, and T. Kohwi-Shigematsu. 2003. Tissue-specific nuclear architecture and gene expression regulated by SATB1. Nat. Genet. 34:42–51.
   PubMed Web of Science ®Google Scholar
• Cai, S., C. C. Lee, and T. Kohwi-Shigematsu. 2006. SATB1 packages densely looped transcriptionally active chromatin for coordinated expression of cytokine genes. Nat. Genet. 38:1278–1288.
   PubMed Web of Science ®Google Scholar
• Chinnadurai, G. 2002. CtBP, an unconventional transcriptional corepressor in development and oncogenesis. Mol. Cell 9:213–224.
   PubMed Web of Science ®Google Scholar
• Dahiya, A., S. Wong, S. Gonzalo, M. Gavin, and D. C. Dean. 2003. Linking the Rb and polycomb pathways. Mol. Cell 8:557–569.
   Google Scholar
• Di Stefano, V., S. Soddu, A. Sacchi, and G. D'Orazi. 2005. HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage. Oncogene 24:5431–5442.
   PubMedGoogle Scholar
• Dobreva, G., J. Dambacher, and R. Grosschedl. 2003. SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression. Genes Dev. 17:3048–3061.
   PubMed Web of Science ®Google Scholar
• Galande, S., L. A. Dickinson, I. S. Mian, M. Sikorska, and T. Kohwi-Shigematsu. 2001. SATB1 cleavage by caspase 6 disrupts PDZ domain-mediated dimerization, causing detachment from chromatin early in T-cell apoptosis. Mol. Cell. Biol. 21:5591–5604.
   PubMed Web of Science ®Google Scholar
• Galande, S., P. K. Purbey, D. Notani, and P. P. Kumar. 2007. The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1. Curr. Opin. Genet. Dev. 17:408–417.
   PubMed Web of Science ®Google Scholar
• Glass, C. K., and M. G. Rosenfeld. 2000. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14:121–141.
   PubMed Web of Science ®Google Scholar
• Grooteclaes, M., Q. Deveraux, J. Hildebrand, Q. Zhang, R. H. Goodman, and S. M. Frisch. 2003. C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs. Proc. Natl. Acad. Sci. USA 100:4568–4573.
   PubMed Web of Science ®Google Scholar
• Hammer, G. D., I. Krylova, Y. Zhang, B. D. Darimont, K. Simpson, N. L. Weigel, and H. A. Ingraham. 1999. Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress. Mol. Cell 3:521–526.
   PubMed Web of Science ®Google Scholar
• Han, H. J., J. Russo, Y. Kohwi, and T. Kohwi-Shigematsu. 2008. SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. Nature 452:187–193.
   PubMed Web of Science ®Google Scholar
• Harris, B. Z., and W. A. Lim. 2001. Mechanism and role of PDZ domains in signaling complex assembly. J. Cell Sci. 114:3219–3231.
   PubMed Web of Science ®Google Scholar
• Hayden, M. S., and S. Ghosh. 2004. Signaling to NF-kappaB. Genes Dev. 18:2195–2224.
   PubMed Web of Science ®Google Scholar
• Katsanis, N., and E. M. Fisher. 1998. A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3. Genomics 47:294–299.
   PubMedGoogle Scholar
• Klein, P. S., and D. A. Melton. 1996. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. USA 93:8455–8459.
   PubMed Web of Science ®Google Scholar
• Kumar, P. P., O. Bischof, P. K. Purbey, D. Notani, H. Urlaub, A. Dejean, and S. Galande. 2007. Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus. Nat. Cell Biol. 9:45–56.
   PubMed Web of Science ®Google Scholar
• Kumar, P. P., P. K. Purbey, D. S. Ravi, D. Mitra, and S. Galande. 2005. Displacement of SATB1-bound histone deacetylase 1 corepressor by the human immunodeficiency virus type 1 transactivator induces expression of interleukin-2 and its receptor in T cells. Mol. Cell. Biol. 25:1620–1633.
   PubMed Web of Science ®Google Scholar
• Kumar, P. P., P. K. Purbey, C. K. Sinha, D. Notani, A. Limaye, R. S. Jayani, and S. Galande. 2006. Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. Mol. Cell 22:231–243.
   PubMed Web of Science ®Google Scholar
• Kumar, P. P., S. Mehta, P. K. Purbey, D. Notani, R. S. Jayani, H. J. Purohit, D. V. Raje, D. S. Ravi, R. R. Bhonde, D. Mitra, and S. Galande. 2007. SATB1-binding sequences and Alu-like motifs define a unique chromatin context in the vicinity of HIV-1 integration sites. J. Virol. 81:5617–5627.
   PubMedGoogle Scholar
• Laia, E. C. 2002. Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins. EMBO Rep. 3:840–845.
   PubMedGoogle Scholar
• Li, S., N. S. Ting, L. Zheng, P. L. Chen, Y. Ziv, Y. Shiloh, E. Y. Lee, and W. H. Lee. 2000. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature 406:210–215.
   PubMed Web of Science ®Google Scholar
• Li, S., P. L. Chen, T. Subramanian, G. Chinnadurai, G. Tomlinson, C. K. Osborne, Z. D. Sharp, and W. H. Lee. 1999. Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage. J. Biol. Chem. 274:11334–11338.
   PubMed Web of Science ®Google Scholar
• Meloni, A. R., C. H. Lai, T. P. Yao, and J. R. Nevins. 2005. A mechanism of COOH-terminal binding protein-mediated repression. Mol. Cancer Res. 3:575–583.
   PubMedGoogle Scholar
• Phippen, T. M., A. L. Sweigart, M. Moniwa, A. Krumm, J. R. Davie, and S. M. Parkhurst. 2000. Drosophila C-terminal binding protein functions as a context-dependent transcriptional co-factor and interferes with both mad and groucho transcriptional repression. J. Biol. Chem. 275:37628–37637.
   PubMedGoogle Scholar
• Postigo, A. A., J. L. Depp, J. J. Taylor, and K. L. Kroll. 2003. Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J. 22:2453–2462.
   PubMedGoogle Scholar
• Purbey, P. K., S. Singh, P. P. Kumar, S. Mehta, K. N. Ganesh, D. Mitra, and S. Galande. 2008. PDZ domain-mediated dimerization and homeodomain-directed specificity are required for high affinity DNA binding by SATB1. Nucleic Acids Res. 36:2107–2122.
   PubMed Web of Science ®Google Scholar
• Riefler, G. M., and B. L. Firestein. 2001. Binding of neuronal nitric-oxide synthase (nNOS) to carboxyl-terminal-binding protein (CtBP) changes the localization of CtBP from the nucleus to the cytosol: a novel function for targeting by the PDZ domain of nNOS. J. Biol. Chem. 276:48262–48268.
   PubMedGoogle Scholar
• Ruland, J., and T. W. Mak. 2003. From antigen to activation: specific signal transduction pathways linking antigen receptors to NF-kappaB. Semin. Immunol. 15:177–183.
   PubMedGoogle Scholar
• Santaguida, M., Q. Ding, G. Berube, M. Truscott, P. Whyte, and A. Nepveu. 2001. Phosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2). J. Biol. Chem. 276:45780–45790.
   PubMed Web of Science ®Google Scholar
• Schaeper, U., T. Subramanian, L. Lim, J. M. Boyd, and G. Chinnadurai. 1998. Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif. J. Biol. Chem. 273:8549–8552.
   PubMed Web of Science ®Google Scholar
• Schaeper, U., J. M. Boyd, S. Verma, E. Uhlmann, T. Subramanian, and G. Chinnadurai. 1995. Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation. Proc. Natl. Acad. Sci. USA 92:10467–10471.
   PubMed Web of Science ®Google Scholar
• Sewalt, R. G., M. J. Gunster, J. van der Vlag, D. P. Satijn, and A. P. Otte. 1999. C-terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins. Mol. Cell. Biol. 19:777–787.
   PubMed Web of Science ®Google Scholar
• Sierra, J., T. Yoshida, C. A. Joazeiro, and K. A. Jones. 2006. The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev. 20:586–600.
   PubMed Web of Science ®Google Scholar
• Staal, F. J., F. Weerkamp, M. R. Baert, C. M. van den Burg, M. van Noort, E. F. de Haas, and J. J. van Dongen. 2004. Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion. J. Immunol. 172:1099–1108.
   PubMedGoogle Scholar
• Tremblay, A., G. B. Tremblay, F. Labrie, and V. Giguère. 1999. Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1. Mol. Cell 3:513–519.
   PubMed Web of Science ®Google Scholar
• Turner, J., and M. Crossley. 2001. The CtBP family: enigmatic and enzymatic transcriptional co-repressors. Bioessays 23:683–690.
   PubMedGoogle Scholar
• Valenta, T., J. Lukas, and V. Korinek. 2003. HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/conductin in human embryonic kidney cells. Nucleic Acids Res. 31:2369–2380.
   PubMedGoogle Scholar
• Vo, N., C. Fjeld, and R. H. Goodman. 2001. Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP. Mol. Cell. Biol. 21:6181–6188.
   PubMedGoogle Scholar
• Wen, J., S. Huang, H. Rogers, L. A. Dickinson, T. Kohwi-Shigematsu, and C. T. Noguchi. 2005. SATB1 family protein expressed during early erythroid differentiation modifies globin gene expression. Blood 105:3330–3339.
   PubMed Web of Science ®Google Scholar
• Yao, Y. L., W. M. Yang, and E. Seto. 2001. Regulation of transcription factor YY1 by acetylation and deacetylation. Mol. Cell. Biol. 21:5979–5991.
   PubMed Web of Science ®Google Scholar
• Yasui, D., M. Miyano, S. Cai, P. Varga-Weisz, and T. Kohwi-Shigematsu. 2002. SATB1 targets chromatin remodelling to regulate genes over long distances. Nature 419:641–645.
   PubMed Web of Science ®Google Scholar
• Zhang, Q., H. Yao, N. Vo, and R. H. Goodman. 2000. Acetylation of adenovirus E1A regulates binding of the transcriptional corepressor CtBP. Proc. Natl. Acad. Sci. USA 97:14323–14328.
   PubMed Web of Science ®Google Scholar
• Zhong, H., M. J. May, E. Jimi, and S. Ghosh. 2002. The phosphorylation status of nuclear NF-κB determines its association with CBP/p300 or HDAC-1. Mol. Cell 9:625–636.
   PubMed Web of Science ®Google Scholar