20
Views
50
CrossRef citations to date
0
Altmetric
Article

A Drosophila pasha Mutant Distinguishes the Canonical MicroRNA and Mirtron Pathways

, , , , , & show all
Pages 861-870 | Received 30 Sep 2008, Accepted 19 Nov 2008, Published online: 21 Mar 2023

REFERENCES

  • Berezikov, E., W.-J. Chung, J. Willis, E. Cuppen, and E. C. Lai. 2007. Mammalian mirtron genes. Mol. Cell 28:328–336.
  • Biemar, F., R. Zinzen, M. Ronshaugen, V. Sementchenko, J. R. Manak, and M. S. Levine. 2005. Spatial regulation of microRNA gene expression in the Drosophila embryo. Proc. Natl. Acad. Sci. USA 102:15907–15911.
  • Brennecke, J., D. R. Hipfner, A. Stark, R. B. Russell, and S. M. Cohen. 2003. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113:25–36.
  • Carmell, M. A., and G. J. Hannon. 2004. RNase III enzymes and the initiation of gene silencing. Nat. Struct. Mol. Biol. 11:214–218.
  • Chong, M. M., J. P. Rasmussen, A. Y. Rudensky, and D. R. Littman. 2008. The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease. J. Exp. Med. 205:2005–2017.
  • Cobb, B. S., T. B. Nesterova, E. Thompson, A. Hertweck, E. O'Connor, J. Godwin, C. B. Wilson, N. Brockdorff, A. G. Fisher, S. T. Smale, and M. Merkenschlager. 2005. T-cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. J. Exp. Med. 201:1367–1373.
  • Denli, A. M., B. B. Tops, R. H. Plasterk, R. F. Ketting, and G. J. Hannon. 2004. Processing of primary microRNAs by the microprocessor complex. Nature 432:231–235.
  • Farazi, T. A., S. A. Juranek, and T. Tuschl. 2008. The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members. Development 135:1201–1214.
  • Flynt, A. S., and E. C. Lai. 2008. Biological principles of microRNA-mediated regulation: shared themes amid diversity. Nat. Rev. Genet. 9:831–842.
  • Forstemann, K., Y. Tomari, T. Du, V. V. Vagin, A. M. Denli, D. P. Bratu, C. Klattenhoff, W. E. Theurkauf, and P. D. Zamore. 2005. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol. 3:e236.
  • Friggi-Grelin, F., L. Lavenant-Staccini, and P. Therond. 2008. Control of antagonistic components of the hedgehog signaling pathway by microRNAs in Drosophila. Genetics 179:429–439.
  • Giraldez, A. J., R. M. Cinalli, M. E. Glasner, A. J. Enright, J. M. Thomson, S. Baskerville, S. M. Hammond, D. P. Bartel, and A. F. Schier. 2005. MicroRNAs regulate brain morphogenesis in zebrafish. Science 308:833–838.
  • Glazov, E. A., P. A. Cottee, W. C. Barris, R. J. Moore, B. P. Dalrymple, and M. L. Tizard. 2008. A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach. Genome Res. 18:957–964.
  • Gregory, R. I., K. P. Yan, G. Amuthan, T. Chendrimada, B. Doratotaj, N. Cooch, and R. Shiekhattar. 2004. The Microprocessor complex mediates the genesis of microRNAs. Nature 432:235–240.
  • Hammond, S. M., E. Bernstein, D. Beach, and G. J. Hannon. 2000. An RNA-directed nuclease mediates posttranscriptional gene silencing in Drosophila cells. Nature 404:293–296.
  • Han, J., Y. Lee, K. H. Yeom, Y. K. Kim, H. Jin, and V. N. Kim. 2004. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18:3016–3027.
  • Han, J., Y. Lee, K. H. Yeom, J. W. Nam, I. Heo, J. K. Rhee, S. Y. Sohn, Y. Cho, B. T. Zhang, and V. N. Kim. 2006. Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125:887–901.
  • Harfe, B. D., M. T. McManus, J. H. Mansfield, E. Hornstein, and C. J. Tabin. 2005. The RNase III enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc. Natl. Acad. Sci. USA 102:10898–10903.
  • Hatfield, S. D., H. R. Shcherbata, K. A. Fischer, K. Nakahara, R. W. Carthew, and H. Ruohola-Baker. 2005. Stem cell division is regulated by the microRNA pathway. Nature 435:974–978.
  • Hay, B. A., T. Wolff, and G. M. Rubin. 1994. Expression of baculovirus P35 prevents cell death in Drosophila. Development 120:2121–2129.
  • Hipfner, D. R., K. Weigmann, and S. M. Cohen. 2002. The bantam gene regulates Drosophila growth. Genetics 161:1527–1537.
  • Jiang, F., X. Ye, X. Liu, L. Fincher, D. McKearin, and Q. Liu. 2005. Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila. Genes Dev. 19:1674–1679.
  • Jin, Z., and T. Xie. 2007. Dcr-1 maintains Drosophila ovarian stem cells. Curr. Biol. 17:539–544.
  • Kataoka, Y., M. Takeichi, and T. Uemura. 2001. Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily. Genes Cells 6:313–325.
  • Lai, E. C., and G. M. Rubin. 2001. neuralized functions cell-autonomously to regulate a subset of Notch-dependent processes during adult Drosophila development. Dev. Biol. 231:217–233.
  • Lai, E. C., B. Tam, and G. M. Rubin. 2005. Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs. Genes Dev. 19:1067–1080.
  • Landthaler, M., A. Yalcin, and T. Tuschl. 2004. The human DiGeorge syndrome critical region gene 8 and its Drosophila melanogaster homolog are required for miRNA biogenesis. Curr. Biol. 14:2162–2167.
  • Lau, N. C. 2004. Molecular characterization of animal microRNAs: sequence, expression, and stability. Ph.D. thesis. Massachusetts Institute of Technology, Cambridge.
  • Lee, R. C., R. L. Feinbaum, and V. Ambros. 1993. The Caenorhabditis elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843–854.
  • Lee, T., and L. Luo. 1999. Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 22:451–461.
  • Lee, Y., C. Ahn, J. Han, H. Choi, J. Kim, J. Yim, J. Lee, P. Provost, O. Radmark, S. Kim, and V. N. Kim. 2003. The nuclear RNase III Drosha initiates microRNA processing. Nature 425:415–419.
  • Lee, Y., K. Jeon, J. T. Lee, S. Kim, and V. N. Kim. 2002. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 21:4663–4670.
  • Lee, Y. S., K. Nakahara, J. W. Pham, K. Kim, Z. He, E. J. Sontheimer, and R. W. Carthew. 2004. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117:69–81.
  • Liu, X., J. K. Park, F. Jiang, Y. Liu, D. McKearin, and Q. Liu. 2007. Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes. RNA 13:2324–2329.
  • Nairz, K., C. Rottig, F. Rintelen, E. Zdobnov, M. Moser, and E. Hafen. 2006. Overgrowth caused by misexpression of a microRNA with dispensable wild-type function. Dev. Biol. 291:314–324.
  • Nakahara, K., K. Kim, C. Sciulli, S. R. Dowd, J. S. Minden, and R. W. Carthew. 2005. Targets of microRNA regulation in the Drosophila oocyte proteome. Proc. Natl. Acad. Sci. USA 102:12023–12028.
  • Newsome, T. P., B. Asling, and B. J. Dickson. 2000. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosiacs. Development 127:851–860.
  • Okamura, K., J. W. Hagen, H. Duan, D. M. Tyler, and E. C. Lai. 2007. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 130:89–100.
  • Okamura, K., A. Ishizuka, H. Siomi, and M. C. Siomi. 2004. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev. 18:1655–1666.
  • Okamura, K., M. D. Phillips, D. M. Tyler, H. Duan, Y. T. Chou, and E. C. Lai. 2008. The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution. Nat. Struct. Mol. Biol. 15:354–363.
  • Rajewsky, N. 2006. microRNA target predictions in animals. Nat. Genet. 38(Suppl. 1):S8–S13.
  • Reinhart, B. J., F. Slack, M. Basson, A. Pasquinelli, J. Bettinger, A. Rougvie, H. R. Horvitz, and G. Ruvkun. 2000. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403:901–906.
  • Rodriguez, A., S. Griffiths-Jones, J. L. Ashurst, and A. Bradley. 2004. Identification of mammalian microRNA host genes and transcription units. Genome Res. 14:1902–1910.
  • Ruby, J. G., C. H. Jan, and D. P. Bartel. 2007. Intronic microRNA precursors that bypass Drosha processing. Nature 448:83–86.
  • Saito, K., A. Ishizuka, H. Siomi, and M. C. Siomi. 2005. Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol. 3:e235.
  • Sarin, S., M. M. O'Meara, E. B. Flowers, C. Antonio, R. J. Poole, D. Didiano, R. J. Johnston, Jr., S. Chang, S. Narula, and O. Hobert. 2007. Genetic screens for Caenorhabditis elegans mutants defective in left/right asymmetric neuronal fate specification. Genetics 176:2109–2130.
  • Sokol, N. S., and V. Ambros. 2005. Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth. Genes Dev. 19:2343–2354.
  • Stark, A., J. Brennecke, R. B. Russell, and S. M. Cohen. 2003. Identification of Drosophila microRNA targets. PLoS Biol. 1:E60.
  • Stowers, R. S., and T. L. Schwarz. 1999. A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype. Genetics 152:1631–1639.
  • Teleman, A. A., S. Maitra, and S. M. Cohen. 2006. Drosophila lacking microRNA miR-278 are defective in energy homeostasis. Genes Dev. 20:417–422.
  • Thibault, S. T., M. A. Singer, W. Y. Miyazaki, B. Milash, N. A. Dompe, C. M. Singh, R. Buchholz, M. Demsky, R. Fawcett, H. L. Francis-Lang, L. Ryner, L. M. Cheung, A. Chong, C. Erickson, W. W. Fisher, K. Greer, S. R. Hartouni, E. Howie, L. Jakkula, D. Joo, K. Killpack, A. Laufer, J. Mazzotta, R. D. Smith, L. M. Stevens, C. Stuber, L. R. Tan, R. Ventura, A. Woo, I. Zakrajsek, L. Zhao, F. Chen, C. Swimmer, C. Kopczynski, G. Duyk, M. L. Winberg, and J. Margolis. 2004. A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac. Nat. Genet. 36:283–287.
  • Wang, Y., R. Medvid, C. Melton, R. Jaenisch, and R. Blelloch. 2007. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat. Genet. 39:380–385.
  • Yang, L., D. Chen, R. Duan, L. Xia, J. Wang, A. Qurashi, P. Jin, and D. Chen. 2007. Argonaute 1 regulates the fate of germline stem cells in Drosophila. Development 134:4265–4272.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.