24
Views
55
CrossRef citations to date
0
Altmetric
Article

Dominant Role for Signal Transduction in the Transcriptional Memory of Yeast GAL Genes

&
Pages 2330-2340 | Received 29 Dec 2009, Accepted 25 Feb 2010, Published online: 20 Mar 2023

REFERENCES

  • Abruzzi, K. C., D. A. Belostotsky, J. A. Chekanova, K. Dower, and M. Rosbash. 2006. 3′-end formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation. EMBO J. 25:4253–4262.
  • Acar, M., A. Becskei, and A. van Oudenaarden. 2005. Enhancement of cellular memory by reducing stochastic transitions. Nature 435:228–232.
  • Bhat, P. J., and T. V. Murthy. 2001. Transcriptional control of the GAL/MEL regulon of yeast Saccharomyces cerevisiae: mechanism of galactose-mediated signal transduction. Mol. Microbiol. 40:1059–1066.
  • Brickner, D. G., I. Cajigas, Y. Fondufe-Mittendorf, S. Ahmed, P. C. Lee, J. Widom, and J. H. Brickner. 2007. H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state. PLoS Biol. 5:e81.
  • Cabal, G. G., A. Genovesio, S. Rodriguez-Navarro, C. Zimmer, O. Gadal, A. Lesne, H. Buc, F. Feuerbach-Fournier, J. C. Olivo-Marin, E. C. Hurt, and U. Nehrbass. 2006. SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope. Nature 441:770–773.
  • Casolari, J. M., C. R. Brown, S. Komili, J. West, H. Hieronymus, and P. A. Silver. 2004. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell 117:427–439.
  • Cavalli, G., and F. Thoma. 1993. Chromatin transitions during activation and repression of galactose-regulated genes in yeast. EMBO J. 12:4603–4613.
  • Chekanova, J. A., K. C. Abruzzi, M. Rosbash, and D. A. Belostotsky. 2008. Sus1, Sac3, and Thp1 mediate post-transcriptional tethering of active genes to the nuclear rim as well as to non-nascent mRNP. RNA 14:66–77.
  • Dion, M. F., T. Kaplan, M. Kim, S. Buratowski, N. Friedman, and O. J. Rando. 2007. Dynamics of replication-independent histone turnover in budding yeast. Science 315:1405–1408.
  • Ferreira, M. E., P. Prochasson, K. D. Berndt, J. L. Workman, and A. P. Wright. 2009. Activator-binding domains of the SWI/SNF chromatin remodeling complex characterized in vitro are required for its recruitment to promoters in vivo. FEBS J. 276:2557–2565.
  • Fischer, T., K. Strasser, A. Racz, S. Rodriguez-Navarro, M. Oppizzi, P. Ihrig, J. Lechner, and E. Hurt. 2002. The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores. EMBO J. 21:5843–5852.
  • Frolova, E., M. Johnston, and J. Majors. 1999. Binding of the glucose-dependent Mig1p repressor to the GAL1 and GAL4 promoters in vivo: regulation by glucose and chromatin structure. Nucleic Acids Res. 27:1350–1358.
  • Gligoris, T., G. Thireos, and D. Tzamarias. 2007. The Tup1 corepressor directs Htz1 deposition at a specific promoter nucleosome marking the GAL1 gene for rapid activation. Mol. Cell. Biol. 27:4198–4205.
  • Hawkins, K. M., and C. D. Smolke. 2006. The regulatory roles of the galactose permease and kinase in the induction response of the GAL network in Saccharomyces cerevisiae. J. Biol. Chem. 281:13485–13492.
  • Hittinger, C. T., and S. B. Carroll. 2007. Gene duplication and the adaptive evolution of a classic genetic switch. Nature 449:677–681.
  • Jani, D., S. Lutz, N. J. Marshall, T. Fischer, A. Kohler, A. M. Ellisdon, E. Hurt, and M. Stewart. 2009. Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol. Cell 33:727–737.
  • Jiang, F., B. R. Frey, M. L. Evans, J. C. Friel, and J. E. Hopper. 2009. Gene activation by dissociation of an inhibitor from a transcriptional activation domain. Mol. Cell. Biol. 29:5604–5610.
  • Johnston, M. 1987. A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae. Microbiol. Rev. 51:458–476.
  • Johnston, M., J. S. Flick, and T. Pexton. 1994. Multiple mechanisms provide rapid and stringent glucose repression of GAL gene expression in Saccharomyces cerevisiae. Mol. Cell. Biol. 14:3834–3841.
  • Kohler, A., M. Schneider, G. G. Cabal, U. Nehrbass, and E. Hurt. 2008. Yeast ataxin-7 links histone deubiquitination with gene gating and mRNA export. Nat. Cell Biol. 10:707–715.
  • Kundu, S., P. J. Horn, and C. L. Peterson. 2007. SWI/SNF is required for transcriptional memory at the yeast GAL gene cluster. Genes Dev. 21:997–1004.
  • Laine, J. P., B. N. Singh, S. Krishnamurthy, and M. Hampsey. 2009. A physiological role for gene loops in yeast. Genes Dev. 23:2604–2609.
  • Lei, E. P., C. A. Stern, B. Fahrenkrog, H. Krebber, T. I. Moy, U. Aebi, and P. A. Silver. 2003. Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex. Mol. Biol. Cell 14:836–847.
  • Lemieux, K., M. Larochelle, and L. Gaudreau. 2008. Variant histone H2A.Z, but not the HMG proteins Nhp6a/b, is essential for the recruitment of Swi/Snf, Mediator, and SAGA to the yeast GAL1 UAS(G). Biochem. Biophys. Res. Commun. 369:1103–1107.
  • Li, X. Y., S. R. Bhaumik, and M. R. Green. 2000. Distinct classes of yeast promoters revealed by differential TAF recruitment. Science 288:1242–1244.
  • Lohr, D. 1984. Organization of the GAL1-GAL10 intergenic control region chromatin. Nucleic Acids Res. 12:8457–8474.
  • Lohr, D., and J. Lopez. 1995. GAL4/GAL80-dependent nucleosome disruption/deposition on the upstream regions of the yeast GAL1-10 and GAL80 genes. J. Biol. Chem. 270:27671–27678.
  • Lohr, D., P. Venkov, and J. Zlatanova. 1995. Transcriptional regulation in the yeast GAL gene family: a complex genetic network. FASEB J. 9:777–787.
  • Meyer, J., A. Walker-Jonah, and C. P. Hollenberg. 1991. Galactokinase encoded by GAL1 is a bifunctional protein required for induction of the GAL genes in Kluyveromyces lactis and is able to suppress the gal3 phenotype in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:5454–5461.
  • Ramsey, S. A., J. J. Smith, D. Orrell, M. Marelli, T. W. Petersen, P. de Atauri, H. Bolouri, and J. D. Aitchison. 2006. Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast. Nat. Genet. 38:1082–1087.
  • Schwabish, M. A., and K. Struhl. 2007. The Swi/Snf complex is important for histone eviction during transcriptional activation and RNA polymerase II elongation in vivo. Mol. Cell. Biol. 27:6987–6995.
  • Sekinger, E. A., Z. Moqtaderi, and K. Struhl. 2005. Intrinsic histone-DNA interactions and low nucleosome density are important for preferential accessibility of promoter regions in yeast. Mol. Cell 18:735–748.
  • Shcheprova, Z., S. Baldi, S. B. Frei, G. Gonnet, and Y. Barral. 2008. A mechanism for asymmetric segregation of age during yeast budding. Nature 454:728–734.
  • Taddei, A., G. Van Houwe, F. Hediger, V. Kalck, F. Cubizolles, H. Schober, and S. M. Gasser. 2006. Nuclear pore association confers optimal expression levels for an inducible yeast gene. Nature 441:774–778.
  • Tan-Wong, S. M., H. D. Wijayatilake, and N. J. Proudfoot. 2009. Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex. Genes Dev. 23:2610–2624.
  • Vodala, S., K. C. Abruzzi, and M. Rosbash. 2008. The nuclear exosome and adenylation regulate posttranscriptional tethering of yeast GAL genes to the nuclear periphery. Mol. Cell 31:104–113.
  • Zacharioudakis, I., T. Gligoris, and D. Tzamarias. 2007. A yeast catabolic enzyme controls transcriptional memory. Curr. Biol. 17:2041–2046.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.