REFERENCES
- Altieri, D. C. 2006. The case for survivin as a regulator of microtubule dynamics and cell-death decisions. Curr. Opin. Cell Biol. 18:609–615.
- Altieri, D. C. 2003. Validating survivin as a cancer therapeutic target. Nat. Rev. Cancer 3:46–54.
- Ambrosini, G., C. Adida, and D. C. Altieri. 1997. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med. 3:917–921.
- Arnaoutov, A., Y. Azuma, K. Ribbeck, J. Joseph, Y. Boyarchuk, T. Karpova, J. McNally, and M. Dasso. 2005. Crm1 is a mitotic effector of Ran-GTP in somatic cells. Nat. Cell Biol. 7:626–632.
- Arnaoutov, A., and M. Dasso. 2003. The Ran GTPase regulates kinetochore function. Dev. Cell 5:99–111.
- Beltrami, E., J. Plescia, J. C. Wilkinson, C. S. Duckett, and D. C. Altieri. 2004. Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis. J. Biol. Chem. 279:2077–2084.
- Bolton, M. A., W. Lan, S. E. Powers, M. L. McCleland, J. Kuang, and P. T. Stukenberg. 2002. Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Mol. Biol. Cell 13:3064–3077.
- Canovas, P. M., and T. M. Guadagno. 2007. Functional analysis of Survivin in spindle assembly in Xenopus egg extracts. J. Cell. Biochem. 100:217–229.
- Carazo-Salas, R. E., O. J. Gruss, I. W. Mattaj, and E. Karsenti. 2001. Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nat. Cell Biol. 3:228–234.
- Carter, S. L., A. C. Eklund, I. S. Kohane, L. N. Harris, and Z. Szallasi. 2006. A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat. Genet. 38:1043–1048.
- Carvalho, A., M. Carmena, C. Sambade, W. C. Earnshaw, and S. P. Wheatley. 2003. Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J. Cell Sci. 116:2987–2998.
- Giet, R., C. Petretti, and C. Prigent. 2005. Aurora kinases, aneuploidy and cancer, a coincidence or a real link? Trends Cell Biol. 15:241–250.
- Giodini, A., M. Kallio, N. R. Wall, G. J. Gorbsky, S. Tognin, P. C. Marchisio, M. Symons, and D. C. Altieri. 2002. Regulation of microtubule stability and mitotic progression by survivin. Cancer Res. 62:2462–2467.
- Gruss, O. J., and I. Vernos. 2004. The mechanism of spindle assembly: functions of Ran and its target TPX2. J. Cell Biol. 166:949–955.
- Gruss, O. J., M. Wittmann, H. Yokoyama, R. Pepperkok, T. Kufer, H. Sillje, E. Karsenti, I. W. Mattaj, and I. Vernos. 2002. Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells. Nat. Cell Biol. 4:871–879.
- Harel, A., and D. J. Forbes. 2004. Importin beta: conducting a much larger cellular symphony. Mol. Cell 16:319–330.
- Hetzer, M., O. J. Gruss, and I. W. Mattaj. 2002. The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. Nat. Cell Biol. 4:E177–E184.
- Jeyaprakash, A. A., U. R. Klein, D. Lindner, J. Ebert, E. A. Nigg, and E. Conti. 2007. Structure of a survivin-borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell 131:271–285.
- Joukov, V., A. C. Groen, T. Prokhorova, R. Gerson, E. White, A. Rodriguez, J. C. Walter, and D. M. Livingston. 2006. The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly. Cell 127:539–552.
- Kalab, P., A. Pralle, E. Y. Isacoff, R. Heald, and K. Weis. 2006. Analysis of a RanGTP-regulated gradient in mitotic somatic cells. Nature 440:697–701.
- Kang, B. H., and D. C. Altieri. 2006. Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein. J. Biol. Chem. 281:24721–24727.
- Klein, U. R., E. A. Nigg, and U. Gruneberg. 2006. Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol. Biol. Cell 17:2547–2558.
- Kline-Smith, S. L., and C. E. Walczak. 2004. Mitotic spindle assembly and chromosome segregation: refocusing on microtubule dynamics. Mol. Cell 15:317–327.
- Knauer, S. K., C. Bier, N. Habtemichael, and R. H. Stauber. 2006. The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function. EMBO Rep. 7:1259–1265.
- Knauer, S. K., O. H. Kramer, T. Knosel, K. Engels, F. Rodel, A. F. Kovacs, W. Dietmaier, L. Klein-Hitpass, N. Habtemichael, A. Schweitzer, J. Brieger, C. Rodel, W. Mann, I. Petersen, T. Heinzel, and R. H. Stauber. 2007. Nuclear export is essential for the tumor-promoting activity of survivin. FASEB J. 21:207–216.
- Koffa, M. D., C. M. Casanova, R. Santarella, T. Kocher, M. Wilm, and I. W. Mattaj. 2006. HURP is part of a Ran-dependent complex involved in spindle formation. Curr. Biol. 16:743–754.
- Kops, G. J., B. A. Weaver, and D. W. Cleveland. 2005. On the road to cancer: aneuploidy and the mitotic checkpoint. Nat. Rev. Cancer 5:773–785.
- Kotwaliwale, C., and S. Biggins. 2006. Microtubule capture: a concerted effort. Cell 127:1105–1108.
- Lens, S. M., G. Vader, and R. H. Medema. 2006. The case for Survivin as mitotic regulator. Curr. Opin. Cell Biol. 18:616–622.
- Lens, S. M., R. M. Wolthuis, R. Klompmaker, J. Kauw, R. Agami, T. Brummelkamp, G. Kops, and R. H. Medema. 2003. Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension. EMBO J. 22:2934–2947.
- Malumbres, M., and M. Barbacid. 2001. To cycle or not to cycle: a critical decision in cancer. Nat. Rev. Cancer 1:222–231.
- Okada, H., and T. W. Mak. 2004. Pathways of apoptotic and non-apoptotic death in tumour cells. Nat. Rev. Cancer 4:592–603.
- Ouellet, V., M. C. Guyot, C. Le Page, A. Filali-Mouhim, C. Lussier, P. N. Tonin, D. M. Provencher, and A. M. Mes-Masson. 2006. Tissue array analysis of expression microarray candidates identifies markers associated with tumor grade and outcome in serous epithelial ovarian cancer. Int. J. Cancer 119:599–607.
- Papaconstantinou, A. D., I. Shanmugam, L. Shan, I. S. Schroeder, C. Qiu, M. Yu, and E. G. Snyderwine. 2006. Gene expression profiling in the mammary gland of rats treated with 7,12-dimethylbenz[a]anthracene. Int. J. Cancer 118:17–24.
- Pihan, G., and S. J. Doxsey. 2003. Mutations and aneuploidy: co-conspirators in cancer? Cancer Cell 4:89–94.
- Quimby, B. B., and M. Dasso. 2003. The small GTPase Ran: interpreting the signs. Curr. Opin. Cell Biol. 15:338–344.
- Rosa, J., P. Canovas, A. Islam, D. C. Altieri, and S. J. Doxsey. 2006. Survivin modulates microtubule dynamics and nucleation throughout the cell cycle. Mol. Biol. Cell 17:1483–1493.
- Sampath, S. C., R. Ohi, O. Leismann, A. Salic, A. Pozniakovski, and H. Funabiki. 2004. The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly. Cell 118:187–202.
- Sandall, S., F. Severin, I. X. McLeod, J. R. Yates III, K. Oegema, A. Hyman, and A. Desai. 2006. A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension. Cell 127:1179–1191.
- Sanderson, H. S., and P. R. Clarke. 2006. Cell biology: Ran, mitosis and the cancer connection. Curr. Biol. 16:R466–R468.
- Sillje, H. H., S. Nagel, R. Korner, and E. A. Nigg. 2006. HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Curr. Biol. 16:731–742.
- Sun, C., D. Nettesheim, Z. Liu, and E. T. Olejniczak. 2005. Solution structure of human survivin and its binding interface with Smac/Diablo. Biochemistry 44:11–17.
- Tsai, M. Y., C. Wiese, K. Cao, O. Martin, P. Donovan, J. Ruderman, C. Prigent, and Y. Zheng. 2003. A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat. Cell Biol. 5:242–248.
- Tulu, U. S., C. Fagerstrom, N. P. Ferenz, and P. Wadsworth. 2006. Molecular requirements for kinetochore-associated microtubule formation in mammalian cells. Curr. Biol. 16:536–541.
- Weis, K. 2003. Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle. Cell 112:441–451.
- Wittmann, T., A. Hyman, and A. Desai. 2001. The spindle: a dynamic assembly of microtubules and motors. Nat. Cell Biol. 3:E28–E34.
- Wittmann, T., M. Wilm, E. Karsenti, and I. Vernos. 2000. TPX2, a novel Xenopus MAP involved in spindle pole organization. J. Cell Biol. 149:1405–1418.
- Xia, F., C. W. Lee, and D. C. Altieri. 2008. Tumor cell dependence on Ran-GTP-directed mitosis. Cancer Res. 68:1826–1833.
- Zhou, J., A. O'Brate, A. Zelnak, and P. Giannakakou. 2004. Survivin deregulation in beta-tubulin mutant ovarian cancer cells underlies their compromised mitotic response to taxol. Cancer Res. 64:8708–8714.