Translational Control of TOP2A Influences Doxorubicin Efficacy

REFERENCES

• Abdelmohsen, K., and M. Gorospe. 2011. Post-transcriptional regulation of cancer traits by HuR. WIRES RNA 1: 214–229.
   Google Scholar
• Abdelmohsen, K., Y. Kuwano, H. H. Kim, and M. Gorospe. 2008. Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol. Chem. 389: 243–255.
   PubMed Web of Science ®Google Scholar
• Abdelmohsen, K., et al. 2007. Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol. Cell 25: 543–557.
   PubMed Web of Science ®Google Scholar
• Abdelmohsen, K., S. Srikantan, Y. Kuwano, and M. Gorospe. 2008. miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels. Proc. Natl. Acad. Sci. U. S. A. 105: 20297–20302.
   PubMed Web of Science ®Google Scholar
• Ambros, V. 2004. The functions of animal microRNAs. Nature 431: 350–355.
   PubMed Web of Science ®Google Scholar
• Bachler, M., R. Schroeder, and U. von Ahsen. 1999. StreptoTag: a novel method for the isolation of RNA-binding proteins. RNA 5: 1509–1516.
   PubMed Web of Science ®Google Scholar
• Bartel, D. P. 2009. MicroRNAs: target recognition and regulatory functions. Cell 8: 215–233.
   Web of Science ®Google Scholar
• Bertrand, R., et al. 1998. Localization of ASH1 mRNA particles in living yeast. Mol. Cell 2: 437–445.
   PubMed Web of Science ®Google Scholar
• Bhattacharyya, S. N., R. Habermacher, U. Martine, E. I. Closs, and W. Filipowicz. 2006. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125: 1111–1124.
   PubMed Web of Science ®Google Scholar
• Bhattacharyya, S. N., R. Habermacher, U. Martine, E. I. Closs, and W. Filipowicz. 2006. Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells. Cold Spring Harbor Symp. Quant. Biol. 71: 513–521.
   PubMedGoogle Scholar
• Burgess, D. J., et al. 2008. Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc. Natl. Acad. Sci. U. S. A. 105: 9053–9058.
   PubMed Web of Science ®Google Scholar
• Champoux, J. J. 2001. DNA topoisomerases: structure, function, and mechanism. Annu. Rev. Biochem. 70: 369–413.
   PubMed Web of Science ®Google Scholar
• Chekulaeva, M., and W. Filipowicz. 2009. Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells. Curr. Opin. Cell Biol. 21: 452–460.
   PubMed Web of Science ®Google Scholar
• Decker, C. J., and R. Parker. 2006. CAR-1 and trailer hitch: driving mRNP granule function at the ER? J. Cell Biol. 173: 159–163.
   PubMedGoogle Scholar
• Dieterich, D. C., A. J. Link, J. Graumann, D. A. Tirrell, and E. M. Schuman. 2006. Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). Proc. Natl. Acad. Sci. U. S. A. 103: 9482–9487.
   PubMed Web of Science ®Google Scholar
• Eiring, A. M., et al. 2010. miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell 140: 652–665.
   PubMed Web of Science ®Google Scholar
• Fujimura, K., J. Katahira, F. Kano, Y. Yoneda, and M. Murata. 2009. Selective localization of PCBP2 to cytoplasmic processing bodies. Biochim. Biophys. Acta 1793: 878–887.
   PubMedGoogle Scholar
• Fusco, D., et al. 2003. Single mRNA molecules demonstrate probabilistic movement in living mammalian cells. Curr. Biol. 13: 161–167.
   PubMed Web of Science ®Google Scholar
• Heck, M. M., W. N. Hittelman, and W. C. Earnshaw. 1988. Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle. Proc. Natl. Acad. Sci. U. S. A. 85: 1086–1090.
   PubMed Web of Science ®Google Scholar
• Hinman, M. N., and H. Lou. 2008. Diverse molecular functions of Hu proteins. Cell. Mol. Life Sci. 65: 3168–3181.
   PubMed Web of Science ®Google Scholar
• Kim, H. H., et al. 2008. Nuclear HuR accumulation through phosphorylation by Cdk1. Genes Dev. 22: 1804–1815.
   PubMed Web of Science ®Google Scholar
• Kim, H. H., et al. 2009. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev. 23: 1743–1748.
   PubMed Web of Science ®Google Scholar
• Kloosterman, W. P., and R. H. Plasterk. 2006. The diverse functions of microRNAs in animal development and disease. Dev. Cell 11: 441–450.
   PubMed Web of Science ®Google Scholar
• Lal, A., et al. 2004. Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J. 23: 3092–3102.
   PubMed Web of Science ®Google Scholar
• Lee, E. K., et al. 2010. hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies. Nat. Struct. Mol. Biol. 17: 732–739.
   PubMed Web of Science ®Google Scholar
• López de Silanes, I., et al. 2003. Role of the RNA-binding protein HuR in colon carcinogenesis. Oncogene 22: 7146–7154.
   PubMed Web of Science ®Google Scholar
• López de Silanes, I., M. Zhan, A. Lal, X. Yang, and M. M. Gorospe. 2004. Identification of a target RNA motif for RNA-binding protein HuR. Proc. Natl. Acad. Sci. U. S. A. 101: 2987–2992.
   PubMed Web of Science ®Google Scholar
• Nitiss, J. L. 2009. DNA topoisomerase II and its growing repertoire of biological functions. Nat. Rev. Cancer 9: 327–337.
   PubMed Web of Science ®Google Scholar
• Nitiss, J. L. 2009. Targeting DNA topoisomerase II in cancer chemotherapy. Nat. Rev. Cancer 9: 338–350.
   PubMed Web of Science ®Google Scholar
• Parsons, G. G., and C. A. Spencer. 1997. Mitotic repression of RNA polymerase II transcription is accompanied by release of transcription elongation complexes. Mol. Cell. Biol. 17: 5791–5802.
   PubMed Web of Science ®Google Scholar
• Porter, A. C., and C. J. Farr. 2004. Topoisomerase II: untangling its contribution at the centromere. Chromosome Res. 12: 569–583.
   PubMedGoogle Scholar
• Shav-Tal, Y., et al. 2004. Dynamics of single mRNPs in nuclei of living cells. Science 304: 1797–1800.
   PubMed Web of Science ®Google Scholar
• Shimogawa, M. M., P. O. Widlund, M. Riffle, M. Ess, and T. N. Davis. 2009. Bir1 is required for the tension checkpoint. Mol. Biol. Cell 20: 915–923.
   PubMed Web of Science ®Google Scholar
• Smith, K., S. Houlbrook, M. Greenall, J. Carmichael, and A. L. Harris. 1993. Topoisomerase IIα coamplification with erbB2 in human primary breast cancer and breast cancer cell lines—relationship to m-AMSA and mitoxantrone sensitivity. Oncogene 8: 933–938.
   PubMed Web of Science ®Google Scholar
• Srikantan, S., and M. Gorospe. HuR function in disease. Front. Biosci., in press.
   Google Scholar
• Stefani, G., and F. J. Slack. 2008. Small non-coding RNAs in animal development. Nat. Rev. Mol. Cell Biol. 9: 219–230.
   PubMed Web of Science ®Google Scholar
• Walker, J. V., and J. L. Nitiss. 2002. DNA topoisomerase II as a target for cancer chemotherapy. Cancer Invest. 20: 570–589.
   PubMed Web of Science ®Google Scholar
• Wang, J. C. 1998. Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine. Q. Rev. Biophys. 31: 107–144.
   PubMed Web of Science ®Google Scholar
• Woessner, R. D., M. R. Mattern, C. K. Mirabelli, R. K. Johnson, and F. H. Drake. 1991. Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells. Cell Growth Differ. 2: 209–214.
   PubMedGoogle Scholar