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Research Article

Association of p107 with Sp1: Genetically Separable Regions of p107 Are Involved in Regulation of E2F- and Sp1-Dependent Transcription

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Pages 5444-5452 | Received 10 May 1995, Accepted 19 Jul 1995, Published online: 30 Mar 2023

REFERENCES

  • Azizkhan, C. J., E. D. Jensen, J. A. Pierce, and M. Wade. 1993. Transcription from TATA-less promoters: dihydrofolate reductase as a model. Crit. Rev. Eukaryotic Gene Expression 3:229–254.
  • Bagchi, S., P. Raychaudhuri, and J. R. Nevins. 1990. Adenovirus E1A protein can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation. Cell 62:659–669.
  • Beijersbergen, R. L., R. M. Kerkhoven, L. Zhu, L. Carlee, P. M. Voorhoeve, and R. Bernards. 1994. E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev. 8:2680–2690.
  • Berg, J. M. 1992. Sp1 and the subfamily of zinc-finger proteins with guanine-rich binding sites. Proc. Natl. Acad. Sci. USA 89:11109–11110.
  • Cao, L., B. Faha, M. Dembski, L. H. Tsai, E. Harlow, and N. Dyson. 1992. Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature (London) 355:176–179.
  • Chellappan, S. P., S. Heibert, M. Mudryj, J. M. Horowitz, and J. R. Nevins. 1991. The E2F transcription factor is a cellular target for the RB protein. Cell 65:1053–1061.
  • Chen, L. I., T. Nishinaka, K. Kwan, I. Kitabayashi, K. Yokoyama, Y. H. F. Fu, S. Grunwald, and R. Chiu. 1994. The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator. Mol. Cell. Biol. 14:4380–4389.
  • Cobrinik, D., P. Whyte, D. S. Peeper, T. Jacks, and R. A. Weinberg. 1993. Cell cycle specific association of E2F with the p130 E1A-binding protein. Genes Dev. 7:2392–2404.
  • Courey, A. J., and R. Tjian. 1988. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell 55:887–898.
  • Courey, A. J., and R. Tjian. 1993. p. 743–771. In S. L. McKnight, and K. R. Yamamoto (ed.), Transcriptional regulation, vol. 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Datta, P., and S. Bagchi. 1994. Repression of the transforming growth factor β1 promoter by the adenovirus oncogene E1A. Identification of a unique GC-rich sequence as a target for E1A repression. J. Biol. Chem. 269:25392–25399.
  • Davies, R., R. Hicks, T. Crook, J. Morris, and K. Vousden. 1993. Human papillomavirus type-16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation. J. Virol. 67:2521–2528.
  • DeCaprio, J. A., J. W. Ludlow, J. Figge, J. Y. Shew, C. M. Lee, N. Dyson, K. Buchkovich, P. Whyte, and E. Harlow. 1989. The cellular 107k protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Cell 58:249–255.
  • Devoto, S. H., M. Mudryj, J. Pines, T. Hunter, and J. R. Nevins. 1992. A cyclin A-protein kinase complex possesses sequence-specific DNA-binding activity: p33 cdk2 is a component of the E2F-cyclin A complex. Cell 68:167–176.
  • Dyson, N., K. Buchkovich, P. Whyte, and E. Harlow. 1989. The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Cell 58:249–255.
  • Dyson, N., and E. Harlow. 1992. Adenovirus E1A targets key regulators of cell proliferation. Cancer Surv. 12:161–195.
  • Ewen, M., B. Faha, E. Harlow, and D. Livingston. 1992. Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins. Science 255:85–87.
  • Ewen, M., Y. Xing, J. B. Lawrence, and D. Livingston. 1991. Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell 66:1155–1164.
  • Ewen, M. E. 1994. The cell cycle and the retinoblastoma protein family. Cancer Metastasis Rev. 13:45–66.
  • Faha, B., M. Ewen, L.-H. Tsai, D. Livingston, and E. Harlow. 1992. Association between human cyclin A and adenovirus E1A-associated p107 protein. Science 255:87–90.
  • Ginsburg, D., G. Vario, T. Chittenden, Z. Xiao, G. Xu, K. Widner, J. A. Decaprio, J. Bentley-Lawrence, and D. Livingston. 1994. E2F-4, a new E2F transcription factor family member, interacts with p107 and has transforming potential. Genes Dev. 8:2665–2679.
  • Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044–1051.
  • Gu, W., K. Bhatia, I. T. Magrath, C. V. Dang, and R. Dalla-Favera. 1994. Binding and suppression of the Myc transcriptional activation domain by p107. Science 264:251–254.
  • Hannon, G. J., D. Demetrick, and D. Beach. 1993. Isolation of the Rb-related protein p130 through its interaction with CDK2 and cyclins. Genes Dev. 7:2378–2391.
  • Helin, K., J. A. Lees, M. Vidal, N. Dyson, E. Harlow, and A. Fattaey. 1992. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell 70:337–350.
  • Hoey, T., R. O. Weinzierl, G. Gill, J. L. Chen, B. D. Dynlacht, and R. Tjian. 1993. Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Cell 72:247–260.
  • Ivey-Hoyle, M., R. Conroy, H. E. Huber, P. J. Goodhart, A. Oliff, and D. C. Heimbrook. 1993. Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol. Cell. Biol. 13:7802–7812.
  • Jackson, S. P., J. J. MacDonald, S. Lees-Miller, and R. Tjian. 1990. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell 63:155–165.
  • Jackson, S. P., and R. Tjian. 1988. O-Glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell 55:125–133.
  • Kadonaga, J. T., K. A. Jones, and R. Tjian. 1986. Promoter specific activation of RNA polymerase II transcription by Sp1. Trends Biochem. Sci. 11: 20–23.
  • Kim, S.-J., U. S. Onwuta, Y. I. Lee, R. Li, M. R. Botchan, and P. D. Robbins. 1992. The retinoblastoma gene product regulates Sp1-mediated transcription. Mol. Cell. Biol. 12:2455.
  • Kingsley, C., and A. Winoto. 1992. Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. Mol. Cell. Biol. 12:4251–4261.
  • Lee, J.-S., K. M. Galvin, and Y. Shi. 1993. Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1. Proc. Natl. Acad. Sci. USA 90:6145–6149.
  • Lees, E., B. F. Faha, V. Dulic, S. I. Reed, and E. Harlow. 1992. Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporarily distinct manner. Genes Dev. 6:1874–1885.
  • Li, Y., C. Graham, S. Lacy, A. M. V. Duncan, and P. Whyte. 1993. The adenovirus E1A-associated 130kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Genes Dev. 7:2366–2377.
  • Li, R., J. D. Knight, S. P. Jackson, R. Tjian, and M. R. Botchan. 1991. Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell 65:493–505.
  • Lillie, J. W., and M. R. Green. 1989. Transcription activation by the adeno-virus E1A protein. Nature (London) 338:39–44.
  • Nevins, J. R. 1992. Transcriptional regulation. A closer look at E2F. Nature (London) 358:375.
  • Nevins, J. R. 1992. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 258:424–429.
  • Pascal, E., and R. Tjian. 1991. Different activation domain of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev. 5:1646–1656.
  • Raychaudhuri, P., S. Bagchi, S. H. Devoto, V. B. Kraus, E. Moran, and J. R. Nevins. 1991. Domains of the adenovirus E1A protein that are required for oncogenic activity are also required for dissociation of cellular transcription factor complexes. Genes Dev. 5:1200–1211.
  • Raychaudhuri, P., R. Rooney, and J. R. Nevins. 1989. Identification of an E1A inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter. EMBO J. 6:4073–4081.
  • Saffer, J. D., S. P. Jackson, and M. B. Annarella. 1991. Developmental expression of Sp1 in the mouse. Mol. Cell. Biol. 11:2189–2199.
  • Saffer, J. D., S. P. Jackson, and S. J. Thurston. 1990. SV40 stimulates expression of the transcription factor Sp1 at the mRNA level. Genes Dev. 4:659–666.
  • Schwarz, J. K., S. H. Devoto, E. J. Smith, S. P. Chellappan, L. Jakoi, and J. R. Nevins. 1993. Interactions of the p107 and Rb proteins with E2F during the cell phosphorylation response. EMBO J. 12:1013.
  • Seto, E., B. Lewis, and T. Shenk. 1993. Interaction between transcription factors Sp1 and YY1. Nature (London) 365:462–464.
  • Shan, B., X. Zhu, P.-L. Chen, T. Durfee, Y. Yang, D. Sharp, and W.-H. Lee. 1992. Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F. Mol. Cell. Biol. 12:5620–5631.
  • Shirodkar, S., M. Ewen, J. A. DeCaprio, J. Morgan, D. M. Livingston, and T. Chittenden. 1992. The transcription factor E2F interacts with the retino-blastoma product and a p107-cyclin A complex in a cell cycle regulated manner. Cell 68:157–166.
  • Sif, S., A. J. Capobianco, and T. D. Gilmore. 1993. The v-Rel oncoprotein increases expression from Sp1 site-containing promoters in chicken embryo fibroblasts. Oncogene 7:2501–2509.
  • Smith, E. J., and J. R. Nevins. 1995. The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A and cdk2. Mol. Cell. Biol. 15:338–344.
  • Udvadia, A. J., K. T. Rogers, P. D. R. Higgins, Y. Murata, K. H. Martin, P. A. Humphrey, and J. M. Horowitz. 1993. Sp1 binds promoter elements regulated by the RB protein and Sp1-mediated transcription is stimulated by the RB coexpression. Proc. Natl. Acad. Sci. USA 90:3265–3269.
  • Udvadia, A. J., D. J. Templeton, and J. M. Horowitz. 1995. Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression. Proc. Natl. Acad. Sci. USA 92:3953–3957.
  • Zamanian, M., and N. B. La Thangue. 1993. Transcriptional repression by the Rb-related protein p107. Mol. Biol. Cell 4:389–396.
  • Zhu, L., S. van den Heuvel, K. Helin, A. Fattaey, M. Ewen, D. Livingston, N. Dyson, and E. Harlow. 1993. Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. Genes Dev. 7:1111–1125.

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