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Research Article

Checkpoint Genes Required To Delay Cell Division in Response to Nocodazole Respond to Impaired Kinetochore Function in the Yeast Saccharomyces cerevisiae

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Pages 6838-6844 | Received 27 Jun 1995, Accepted 07 Sep 1995, Published online: 30 Mar 2023

REFERENCES

  • Adams, A. E. M., and J. R. Pringle. 1984. Relationship of actin and tubulin distribution to bud growth in wild type and morphogenetic mutants of Sac-charomyces cerevisiae. J. Cell Biol. 98:934–945.
  • Andreassen, P. R., and R. L. Margolis. 1991. Induction of partial mitosis in BHK cells by 2-aminopurine. J. Cell Sci. 100:299–310.
  • Andreassen, P. R., and R. L. Margolis. 1994. Microtubule dependence of p34(CDC2) inactivation and mitotic exit in mammalian cells. J. Cell Biol. 127:789–802.
  • Burke, D., P. Gasdaska, and L. Hartwell. 1989. Dominant effects of tubulin overexpression in Saccharomyces cerevisiae. Mol. Cell. Biol. 9:1049–1059.
  • Cottarel, G., J. H. Shero, P. Hieter, and J. H. Hegemann. 1989. A 125-base-pair CEN6 DNA fragment is sufficient for complete meiotic and mitotic cen-tromere functions in Saccharomyces cerevisiae. Mol. Cell. Biol. 9:3342–3349.
  • DeBrabander, M. J., R. M. L. Vande Veire, F. E. M. Aerts, M. Borgers, and P. A. J. Janssen. 1976. The effect of methyl(5-(2-thienylcarbonyl)-1H-benz-imidazole-2-yl)carbamate (R17934; NSC 238159), a new synthetic antitu-moral drug interfering with microtubules on mammalian cells cultured in vitro. Cancer Res. 36:905–916.
  • Doheny, K. F., P. K. Sorger, A. A. Hyman, S. Tugendreich, F. Spencer, and P. Hieter. 1993. Identification of essential components of the S. cerevisiae kinetochore. Cell 73:761–774.
  • Earnshaw, W. C., R. L. Bernat, C. A. Cooke, and N. F. Rothfield. 1991. Role of the centromere/kinetochore in cell cycle control. Cold Spring Harbor Symp. Quant. Biol. 56:675–685.
  • Goh, P., and J. V. Kilmartin. 1993. NDC10: a gene involved in chromosome segregation in Saccharomyces cerevisiae. J. Cell Biol. 121:503–512.
  • Gorbsky, G. J., and W. A. Ricketts. 1993. Differential expression of a phos-phoepitope at the kinetochores of moving chromosomes. J. Cell Biol. 122: 1311–1321.
  • Hegemann, J. H., J. H. Shero, G. Cottarel, P. Philippsen, and P. Hieter. 1988. Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae. Mol. Cell. Biol. 8:2523–2535.
  • Hoyt, M. A., L. Totis, and B. T. Roberts. 1991. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell 66:507–517.
  • Hyman, A. A., K. Middleton, M. Centola, T. J. Mitchison, and J. Carbon. 1992. Microtubule-motor activity of a yeast centromere-binding protein complex. Nature (London) 359:533–536.
  • Jacobs, C. W., A. E. M. Adams, P. J. Szaniszlo, and J. R. Pringle. 1988. Functions of microtubules in the Saccharomyces cerevisiae cell cycle. J. Cell Biol. 107:1409–1426.
  • Jiang, W., J. Lecher, and J. Carbon. 1993. Isolation and characterization of a gene (CBF2) specifying a protein component of the budding yeast kineto-chore. J. Cell Biol. 121:513–519.
  • Jordan, M. A., D. Thrower, and L. Wilson. 1991. Mechanism of inhibition of cell proliferation by vinca alkaloids. Cancer Res. 51:2212–2222.
  • Jordan, M. A., D. Thrower, and L. Wilson. 1992. Effect of vinblastine, podophyllotoxin and nocodazole on mitotic spindles: implication for the rate of microtubule dynamics in mitosis. J. Cell Sci. 102:401–416.
  • Jordan, M. A., R. J. Toso, D. Thrower, and L. Wilson. 1993. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc. Natl. Acad. Sci. USA 90:9552–9556.
  • Jordan, M. A., and L. Wilson. 1990. Kinetic analysis of tubulin exchange at microtubule ends at low vinblastine concentrations. Biochemistry 29:2730–2739.
  • Kilmartin, J. V., and A. E. Adams. 1984. Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J. Cell Biol. 98:922–933.
  • Kubiak, J. Z., M. Weber, H. D. Pennart, N. J. Winston, and B. Maro. 1993. The metaphase II arrest in mouse oocytes is controlled through microtubule-dependent destruction of cyclin B in the presence of CSF. EMBO J. 12: 3773–3778.
  • Lechner, J. 1994. A zinc finger protein, essential for chromosome segregation, constitutes a putative DNA binding subunit of the Saccharomyces cerevisiae kinetochore complex Cbf3. EMBO J. 13:5203–5211.
  • Lechner, J., and J. Carbon. 1991. A 240 kD multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell 64:717–725.
  • Li, R., and A. W. Murray. 1991. Feedback control of mitosis in budding yeast. Cell 66:519–531.
  • Li, X., and R. B. Nicklas. 1995. Mitotic forces control a cell-cycle checkpoint. Nature (London) 373:630–632.
  • Ng, R., and J. Carbon. 1987. Mutational and in vitro protein-binding studies on centromere DNA from Saccharomyces cerevisiae. Mol. Cell. Biol. 7:4522–4534.
  • Owellen, R. J., C. A. Hartke, R. M. Dickerson, and F. O. Hains. 1976. Inhibition of tubulin-microtubule polymerization by drugs of the vinca alkaloid class. Cancer Res. 36:1499–1502.
  • Rieder, C. L., A. Schultz, R. Cole, and G. Sluder. 1994. Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle. J. Cell Biol. 127:1301–1310.
  • Rowinsky, E. K., and R. C. Donehower. 1991. The clinical pharmacology and use of antimicrotubule agents in cancer chemotherapeutics. Pharmacol. Ther. 52:35–84.
  • Sherman, F., G. Fink, and J. B. Hicks. 1986. Methods in yeast genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Sorger, P. K., F. F. Severin, and A. A. Hyman. 1994. Factors required for the binding of reassembled yeast kinetochores to microtubules in vitro. J. Cell Biol. 127:995–1008.
  • Spencer, F., S. L. Gerring, C. Connelly, and P. Hieter. 1990. Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae. Genetics 124:237–249.
  • Spencer, F., and P. Hieter. 1992. Centromere DNA mutations induce a mitotic delay in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 89: 8908–8912.
  • Strunnikov, A. V., J. Kingsbury, and D. Koshland. 1995. CEP3 encodes a centromere protein of Saccharomyces cerevisiae. J. Cell Biol. 128:749–760.
  • Tavormina, P. Personal communication.
  • Tomkiel, J., C. A. Cooke, H. Saitoh, R. L. Bernat, and W. C. Earnshaw. 1994. CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase. J. Cell Biol. 125:531–545.
  • Toso, R. J., M. A. Jordan, K. W. Farrell, B. Matsumoto, and L. Wilson. 1993. Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine. Biochemistry 32:1285–1293.
  • Wang, X., N. Yew, J. G. Peloquin, G. F. Vandewoude, and G. G. Borisy. 1994. Mos oncogene product associates with kinetochores in mammalian somatic cells and disrupts mitotic progression. Proc. Natl. Acad. Sci. USA 91:8329–8333.
  • Wendell, K. L., L. Wilson, and M. A. Jordan. 1993. Mitotic block in HeLa cells by vinblastine: ultrastructural changes in kinetochore-microtubule attachment and in centrosomes. J. Cell Sci. 104:261–274.
  • Zirkle, R. E. 1970. Involvement of the prometaphase kinetochore in prevention of precocious anaphase. J. Cell Biol. 47:235a.

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