Characterization of the Cooperative Function of Inhibitory Sequences in Ets-1

REFERENCES

• Carey, J. 1991. Gel retardation. Methods Enzymol. 208:103–117.
   PubMedGoogle Scholar
• Dalton, S., and R. Treisman. 1992. Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell 68:597–612.
   PubMed Web of Science ®Google Scholar
• Doering, D. S. 1992. Ph.D. thesis. Massachusetts Institute of Technology, Cambridge, Mass.
   Google Scholar
• Donaldson, L. W., J. M. Petersen, B. J. Graves, and L. P. McIntosh. 1994. Secondary structure of the ETS domain places murine Ets-1 in the super-family of winged helix-turn-helix DNA-binding proteins. Biochemistry 33:13509–13516.
   PubMed Web of Science ®Google Scholar
• Donaldson, L. W., J. M. Petersen, B. J. Graves, and L. P. McIntosh. 1996. Solution structure of the ETS domain from murine Ets-1: a winged helix-turn-helix DNA binding motif. EMBO J. 15:125–134.
   PubMed Web of Science ®Google Scholar
• Dudek, H., R. V. Tantravahi, V. N. Rao, E. S. P. Reddy, and E. P. Reddy. 1992. Myb and Ets proteins cooperate in transcriptional activation of the mim-1 promoter. Proc. Natl. Acad. Sci. USA 89:1291–1295.
   PubMedGoogle Scholar
• Erpel, T., G. Superti-Furga, and S. Courtneidge. 1995. Mutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactions. EMBO J. 14:963–975.
   PubMed Web of Science ®Google Scholar
• Fisher, R. J., M. Favash, J. Casas-Finet, J. W. Erickson, A. Kondoh, S. V. Bladen, C. Fisher, D. K. Watson, and T. Papas. 1994. Real-time DNA binding measurements of the ETS1 recombinant oncoproteins reveal significant kinetic differences between the p42 and p51 isoforms. Protein Sci. 3:257–266.
   PubMed Web of Science ®Google Scholar
• Fisher, R. J., G. Mavrothalassitis, A. Kondoh, and T. S. Papas. 1991. High-affinity DNA-protein interactions of the cellular ETS1 protein: the determination of the ETS binding motif. Oncogene 6:2249–2254.
   PubMedGoogle Scholar
• Fleischman, L. F., A. M. Pilaro, K. Murakami, A. Kondoh, R. J. Fisher, and T. S. Papas. 1993. c-Ets-1 protein is hyperphosphorylated during mitosis. Oncogene 8:771–780.
   PubMedGoogle Scholar
• Frankel, A. D., and P. S. Kim. 1991. Modular structure of transcription factors: implications for gene regulation. Cell 65:717–719.
   PubMed Web of Science ®Google Scholar
• Fried, M. G. 1989. Measurement of protein-DNA interaction parameters by electrophoresis mobility shift assay. Electrophoresis 10:366–376.
   PubMed Web of Science ®Google Scholar
• Gegonne, A., R. Bosselut, R. Bailly, and J. Ghysdael. 1993. Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1. EMBO J. 12:1169–1178.
   PubMed Web of Science ®Google Scholar
• Giese, K., C. Kingsley, J. R. Kirshner, and R. Grosschedl. 1995. Assembly and function of a TCRa enhancer complex is dependent on LEF-1 induced DNA bending and multiple protein-protein interactions. Genes Dev. 9:995–1008.
   PubMed Web of Science ®Google Scholar
• Gill, S. C., and P. H. von Hippel. 1989. Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem. 182:319–326.
   PubMed Web of Science ®Google Scholar
• Giovane, A., A. Pintzas, S. Maira, P. Sobieszczuk, and B. Wasylyk. 1994. Net, a new ets transcription factor that is activated by Ras. Genes Dev. 8:1502–1513.
   PubMed Web of Science ®Google Scholar
• Golay, J., M. Introna, and T. Graf. 1988. A single point mutation in the v-ets oncogene affects both erythroid and myelomonocytic cell differentiation. Cell 55:1147–1158.
   PubMedGoogle Scholar
• Green, M., T. J. Schuetz, E. K. Sullivan, and R. E. Kingston. 1995. A heat shock-responsive domain of human HSF that regulates transcription activation domain function. Mol. Cell. Biol. 15:3354–3362.
   PubMed Web of Science ®Google Scholar
• Grimm, S., and P. A. Baeuerle. 1993. The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits. Bio-chem. J. 290:297–308.
   PubMed Web of Science ®Google Scholar
• Gunther, C. V., and B. J. Graves. 1994. Identification of ETS domain proteins in murine T lymphocytes that interact with the Moloney murine leukemia virus enhancer. Mol. Cell. Biol. 14:7569–7580.
   PubMedGoogle Scholar
• Hager, D. A., and R. R. Burgess. 1980. Elution of proteins from sodium dodecyl sulfate, and renaturation of enzymatic activity: results with sigma subunit of E. coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes. Anal. Biochem. 109:76–86.
   PubMed Web of Science ®Google Scholar
• Hagman, J., and R. Grosschedl. 1992. An inhibitory carboxyl terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene. Proc. Natl. Acad. Sci. USA 89:8889–8893.
   PubMed Web of Science ®Google Scholar
• Hahn, S. L., and B. Wasylyk. 1994. The oncoprotein v-Ets is less selective in DNA binding than c-Ets-1 due to the C-terminal sequence change. Oncogene 9:2499–2512.
   PubMedGoogle Scholar
• Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Hupp, T. R., D. W. Meek, C. A. Midgley, and D. P. Lane. 1992. Regulation of the specific DNA binding function of p53. Cell 71:875–886.
   PubMed Web of Science ®Google Scholar
• Hupp, T. R., A. Sparks, and D. P. Lane. 1995. Small peptides activate the latent sequence-specific DNA binding function of p53. Cell 83:237–245.
   PubMed Web of Science ®Google Scholar
• Kemp, B. E., and R. B. Pearson. 1991. Intrasteric regulation of protein kinases and phosphatases. Biochim. Biophys. Acta 1094:67–76.
   PubMedGoogle Scholar
• Kowenz-Leutz, E., G. Twamley, S. Ansieau, and A. Leutz. 1994. Novel mechanism of C/EBP (NF-M) transcriptional control: activation through derepression. Genes Dev. 8:2781–2791.
   PubMed Web of Science ®Google Scholar
• Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680–685.
   PubMed Web of Science ®Google Scholar
• Leprince, D., A. Gegonne, J. Coll, C. de Taisne, A. Schneeberger, C. Lagrou, and D. Stehelin. 1983. A putative second cell-derived oncogene of the avian leukaemia retrovirus E26. Nature (London) 306:395–397.
   PubMed Web of Science ®Google Scholar
• Liang, H., X. Mao, E. Olenjniczak, D. G. Nettesheim, L. Yu, R. P. Meadows, C. B. Thompson, and S. W. Fesik. 1994. Solution structure of the ets domain of Fli-1 when bound to DNA. Nat. Struct. Biol. 1:871–876.
   PubMedGoogle Scholar
• Lieberman, P. M., M. C. Schmidt, C. C. Kao, and A. J. Berk. 1991. Two distinct domains in the yeast transcription factor IID and evidence for a TATA box-induced conformational change. Mol. Cell. Biol. 11:63–74.
   PubMedGoogle Scholar
• Lim, F., N. Kraut, J. Frampton, and T. Graf. 1992. DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism. EMBO J. 11:643–652.
   PubMed Web of Science ®Google Scholar
• Nelsen, B., T. Gang, B. Erman, J. Gregoire, R. Maki, B. Graves, and R. Sen. 1993. Regulation of lymphoid-specific immunoglobulin μ heavy chain gene enhancer by ETS-domain proteins. Science 261:82–86.
   PubMed Web of Science ®Google Scholar
• Nunn, M. F., P. H. Seeburg, C. Moscovici, and P. H. Duesberg. 1983. Tripartite structure of the avian erythroblastosis virus E26 transforming gene. Nature (London) 306:391–395.
   PubMed Web of Science ®Google Scholar
• Nye, J. A., J. M. Petersen, C. V. Gunther, M. D. Jonsen, and B. J. Graves. 1992. Interaction of murine Ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif. Genes Dev. 6:975–990.
   PubMed Web of Science ®Google Scholar
• Petersen, J., T. Gu, N. Speck, and B. Graves. Unpublished data.
   Google Scholar
• Petersen, J. M., J. J. Skalicky, L. W. Donaldson, L. P. McIntosh, T. Alber, and B. J. Graves. 1995. Modulation of transcription factor Ets-1 DNA binding: DNA-induced unfolding of an alpha helix. Science 269:1866–1869.
   PubMed Web of Science ®Google Scholar
• Pognonec, P., K. E. Boulukos, J. C. Gesquiere, D. Stehelin, and J. Ghysdael. 1988. Mitogenic stimulation of thymocytes results in the calcium-dependent phosphorylation of c-ets-1 proteins. EMBO J. 7:977–983.
   PubMedGoogle Scholar
• Rabault, B., and J. Ghysdael. 1994. Calcium-induced phosphorylation of ETS1 inhibits its specific DNA binding activity. J. Biol. Chem. 269:28143–28151.
   PubMed Web of Science ®Google Scholar
• Rabindran, S. K., R. I. Haroun, J. Clos, J. Wisniewski, and C. Wu. 1993. Regulation of heat shock factor trimer formation: role of a conserved leucine zipper. Science 259:230–234.
   PubMed Web of Science ®Google Scholar
• Shapiro, L. H. 1995. Myb and Ets proteins cooperate to transactivate an early myeloid gene. J. Biol. Chem. 270:8763–8771.
   PubMedGoogle Scholar
• Shi, Y., P. E. Kroeger, and R. I. Morimoto. 1995. The carboxyl-terminal transactivation domain of heat shock factor 1 is negatively regulated and stress responsive. Mol. Cell. Biol. 15:4309–4318.
   PubMed Web of Science ®Google Scholar
• Skalicky, J. J., L. W. Donaldson, J. M. Petersen, B. J. Graves, and L. P. McIntosh. 1996. Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets-1. Protein Sci. 5:296–309.
   PubMedGoogle Scholar
• Soderling, T. R. 1990. Protein kinases: regulation by auto-inhibitory domains. J. Biol. Chem. 265:1823–1826.
   PubMedGoogle Scholar
• Soudant, J., O. Albabli, P. Dhordain, A. Flourens, D. Stehelin, and D. Leprince. 1994. A residue of the ETS domain mutated in the v-ets oncogene is essential for the DNA-binding and transactivating properties of the ETS-1 and ETS-2 proteins. Nucleic Acids Res. 22:3871–3879.
   PubMedGoogle Scholar
• Sun, W., B. J. Graves, and N. A. Speck. 1995. Transactivation of the Moloney murine leukemia virus and T-cell receptor β-chain enhancers by cbf and ets requires intact binding sites for both proteins. J. Virol. 69:4941–4949.
   PubMed Web of Science ®Google Scholar
• Thompson, C. C., T. A. Brown, and S. L. McKnight. 1991. Convergence of Ets- and Notch-related structural motifs in a heteromeric DNA binding complex. Science 253:762–768.
   PubMed Web of Science ®Google Scholar
• Wasylyk, C., P. Flores, A. Gutman, and B. Wasylyk. 1989. PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes. EMBO J. 8:3371–3378.
   PubMedGoogle Scholar
• Wasylyk, C., J.-P. Kerckaert, and B. Wasylyk. 1992. A novel modulator domain of Ets transcription factors. Genes Dev. 6:965–974.
   PubMed Web of Science ®Google Scholar
• Wasylyk, C., and B. Wasylyk. 1993. Oncogenic conversion of Ets affects redox regulation in-vivo and in-vitro. Nucleic Acids Res. 21:523–529.
   PubMedGoogle Scholar
• Werner, M. H., G. M. Clore, C. L. Fisher, R. J. Fisher, L. Tring, J. Shiloach, and A. M. Cronenborn. 1995. The solution structure of the human ETS1-DNA complex reveals a novel mode of binding and true side chain intercalation. Cell 83:761–771.
   PubMedGoogle Scholar
• Williams, S. C., M. Baer, A. J. Dillner, and P. F. Johnson. 1995. CRP(C/ EBPβ) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity. EMBO J. 14:3170–3183.
   PubMed Web of Science ®Google Scholar
• Woods, D. B., J. Ghysdael, and M. J. Owen. 1992. Identification of nucleotide preferences in DNA sequence recognized specifically by c-Ets-1 protein. Nucleic Acids Res. 20:699–704.
   PubMedGoogle Scholar
• Wotton, D., J. Ghysdael, S. Wang, N. A. Speck, and M. J. Owen. 1994. Cooperative binding of Ets-1 and core binding factor to DNA. Mol. Cell. Biol. 14:840–850.
   PubMed Web of Science ®Google Scholar
• Zou, J., D. Rungger, and R. Voellmy. 1995. Multiple layers of regulation of human heat shock transcription factor 1. Mol. Cell. Biol. 15:4319–4330.
   PubMedGoogle Scholar