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Research Article

An Exceptionally Conserved Transcriptional Repressor, CTCF, Employs Different Combinations of Zinc Fingers To Bind Diverged Promoter Sequences of Avian and Mammalian c-myc Oncogenes

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Pages 2802-2813 | Received 19 Sep 1995, Accepted 06 Mar 1996, Published online: 29 Mar 2023

REFERENCES

  • Bogenhagen, D. F. 1993. Proteolytic footprinting of transcription factor TFIIIA reveals different tightly binding sites for 5S RNA and 5S DNA. Mol. Cell. Biol. 13:5149–5158.
  • Casaregola, S., A. Jacq, D. Laoudj, G. McGurk, S. Margarson, M. Tempete, V. Norris, and I. B. Holland. 1992. Cloning and analysis of the entire Escherichia coli ams gene: ams is identical to hmpl and encodes a 114 kDa protein that migrates as a 180 kDa protein. J. Mol. Biol. 228:30–40.
  • Collins, S. J., R. C. Gallo, and R. E. Gallagher. 1977. Continuous growth and differentiation of human myeloid leukemia cells in suspension culture. Nature (London) 270:347–349.
  • Eick, D., F. Kohlhuber, D. A. Wolf, and L. J. Strobl. 1994. Activation of pausing RNA polymerases by nuclear run-on experiments. Anal. Biochem. 218:347–351.
  • El-Baradi, T., and P. Tomas. 1991. Zinc finger proteins: what we know and what we would like to know. Mech. Dev. 35:155–169.
  • Filippova, G. N., P. E. Neiman, S. J. Collins, and V. V. Lobanenkov. Unpublished data.
  • Franklin, A. J., T. L. Jetton, K. D. Shelton, and M. A. Magnuson. 1994. BZP, a novel serum-responsive zinc finger protein that inhibits gene transcription. Mol. Cell. Biol. 14:6773–6788.
  • Funabiki, T., B. L. Kreider, and J. N. Ihle. 1994. The carboxyl domain of zinc fingers of the Evi-1 myeloid transforming gene binds a consensus sequence of GAAGATGAG. Oncogene 9:1575–1581.
  • Hromas, R., S. J. Collins, D. Hickstein, W. Raskind, L. L. Deaven, P. O'Hara, F. S. Hagen, and K. Kaushansky. 1991. A retinoic acid-responsive human zinc finger gene, MZF1, preferentially expressed in myeloid cells. J. Biol. Chem. 266:14183–14187.
  • Ishida, S., K. Shudo, S. Takada, and K. Koike. 1994. Transcription from the P2 promoter of human protooncogene myc is suppressed by retinoic acid through an interaction between the E2F element and its binding proteins. Cell Growth Differ. 5:287–294.
  • Kakidani, H., and M. Ptashne. 1988. Gal4 activates gene expression in mammalian cells. Cell 52:161–167.
  • Kinzler, K. W., J. M. Ruppert, S. H. Bigner, and B. Vogelstein. 1988. The GLI gene is a member of the Krnppel family of zinc finger proteins. Nature (London) 332:371–374.
  • Klenova, E. M., G. N. Filippova, C. Meyers, S. Fagerlie, P. E. Neiman, G. H. Goodwin, and V. V. Lobanenkov. Unpublished data.
  • Klenova, E. M., G. N. Filippova, P. E. Neiman, G. H. Goodwin, and V. V. Lobanenkov. Functional regulation of the chicken c-myc transcriptional repressor CTCF by phosphorylation. Submitted for publication.
  • Klenova, E. M., R. H. Nicolas, H. F. Paterson, A. F. Carne, C. M. Heath, G. H. Goodwin, P. E. Neiman, and V. V. Lobanenkov. 1993. CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms. Mol. Cell. Biol. 13:7612–7624.
  • Ko, L. J., M. Yamamoto, M. W. Leonard, K. M. George, P. Ting, and J. D. Engel. 1991. Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor δ gene enhancer. Mol. Cell. Biol. 11:2778–2784.
  • Kohlhuber, F., L. J. Strobl, and D. Eick. 1993. Early down-regulation of c-myc in dimethylsulfoxide-induced mouse erythroleukemia (MEL) cells is mediated at the P1/P2 promoters. Oncogene 8:1099–1102.
  • Krumm, A., T. Meulia, M. Brunvand, and M. Groudine. 1992. The block to transcriptional elongation within the c-myc gene is determined in the promoter-proximal region. Genes Dev. 6:2201–2213.
  • Lavery, D. J., and U. Schibler. 1993. Circadian transcription of the cholesterol 7a hydroxylase gene may involve the liver-enriched bZIP protein DBP. Genes Dev. 7:1871–1884.
  • Lewin, B. 1990. Genes IV, p. 504–506. Oxford University Press, New York.
  • Lipp, M., R. Schilling, S. Wiest, G. Laux, and G. W. Bornkamm. 1987. Target sequences for cis-acting regulation within the dual promoter of the human c-myc gene. Mol. Cell. Biol. 7:1393–1400.
  • Lobanenkov, V., and G. Goodwin. 1989. CCCTC-binding protein: a new nuclear protein factor which interaction with 5′-flanking sequence of chicken c-myc oncogene correlates with repression of the gene. Proc. Acad. USSR (Moscow) 309:741–745.
  • Lobanenkov, V. V., V. V. Adler, E. M. Klenova, R. H. Nicolas, and G. H. Goodwin. 1989. CCCTC-binding factor (CTCF): a novel sequence-specific DNA binding protein which interacts with the 5′-flanking sequence of the chicken c-myc gene, p. 45–68. In T. S. Papas (ed.), Gene regulation and AIDS: transcriptional activation, retroviruses and pathogens. Portfolio Publishing Corp., Woodlands, Tex.
  • Lobanenkov, V. V., R. H. Nicolas, V. V. Adler, H. Paterson, E. M. Klenova, A. V. Polotskaja, and G. H. Goodwin. 1990. A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5′ flanking sequence of the chicken c-myc gene. Oncogene 5:1743–1753.
  • Lobanenkov, V. V., R. H. Nicolas, M. A. Plumb, C. A. Wright, and G. H. Goodwin. 1986. Sequence-specific DNA-binding proteins which interact with (G + C)-rich sequences flanking the chicken c-myc gene. Eur. J. Biochem. 159:181–188.
  • Luckow, B., and G. Schutz. 1987. CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res. 15:5490.
  • Marcu, K. B., S. A. Bossone, and A. J. Pate. 1992. Myc function and regulation. Annu. Rev. Biochem. 61:809–860.
  • Maxam, A. M., and W. Gilbert. 1980. Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 65:499–560.
  • Morishita, K., D. S. Parker, M. L. Mucenski, N. A. Jenkins, N. G. Copeland, and J. N. Ihle. 1988. Retroviral activation of a novel gene encoding a zinc-finger protein in IL-3-dependent myeloid leukemia cell lines. Cell 54:831–840.
  • Morris, J. F., R. Hromas, and F. J. Rauscher III. 1994. Characterization of the DNA-binding properties of the myeloid zinc finger protein MZF1: two independent DNA-binding domains recognize two DNA consensus sequences with a common G-rich core. Mol. Cell. Biol. 14:1786–1795.
  • Packham, G., and J. L. Cleveland. 1995. c-Myc and apoptosis. Biochim. Biophys. Acta 1242:11–28.
  • Perkins, A. S., R. Fishel, N. A. Jenkins, and N. G. Copeland. 1991. Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein. Mol. Cell. Biol. 11:2665–2674.
  • Petryniak, B., L. M. Staudt, C. E. Postema, W. T. McCormack, and C. B. Thompson. 1990. Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors have been highly conserved during vertebrate evolution. Proc. Natl. Acad. Sci. USA 87:1099–1103.
  • Query, C. C., R. C. Bentley, and J. D. Keene. 1989. A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein. Cell 57:89–101.
  • Sadowski, I., and M. Ptashne. 1989. A vector for expressing Gal (1-147) fusions in mammalian cells. Nucleic Acids Res. 17:7539.
  • Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Seed, B., and J.-Y. Sheen. 1988. A simple phase-extraction assay for chloramphenicol acetyltransferase activity. Gene 67:271–277.
  • Shuman, J. D., C. R. Vinson, and S. L. McKnight. 1990. Evidence of changes in protease sensitivity and subunit exchange rate on DNA binding by C/EBP. Science 249:771–774.
  • Sollenberger, K., T. Kao, and E. Taparowsky. 1994. Structural analysis ofthe chicken max gene. Oncogene 9:661–664.
  • Spencer, C. A., and M. Groudine. 1991. Control of c-myc regulation in normal and neoplastic cells. Adv. Cancer Res. 56:1–48.
  • Strobl, L. J., and D. Eick. 1992. Hold back of RNA polymerase II at the transcription start site mediates down-regulation of c-myc in vivo. EMBO J. 11:3307–3314.
  • Strobl, L. J., F. Kohlhuber, J. Mautner, A. Polack, and D. Eick. 1993. Absence of a paused transcription complex from the c-myc P2 promoter of the translocation chromosome in Burkitt's lymphoma cells: implication for the c-myc P1/P2 promoter shift. Oncogene 8:1437–1447.
  • Suzuki, M., M. Gerstein, and N. Yagi. 1994. Stereochemical basis of DNA recognition by Zn fingers. Nucleic Acids Res. 22:3397–3405.
  • Watson, D. K., M. J. McWilliams, P. Lapis, J. A. Lautenberger, C. W. Schweinfest, and T. S. Papas. 1988. Mammalian ets-1 and ets-2 genes encode highly conserved proteins. Proc. Natl. Acad. Sci. USA 85:7862–7866.

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