Sp1 Binds Two Sites in the CD11c Promoter In Vivo Specifically in Myeloid Cells and Cooperates with AP1 to Activate Transcription

REFERENCES

• Ackerman, S. L., A. G. Minden, and C. Y. Yeung. 1993. The minimal selfsufficient element in a murine G+C-rich promoter is a large element with imperfect dyad symmetry. Proc. Natl. Acad. Sci. USA 90:11865–11869.
   PubMedGoogle Scholar
• Adams, D. O., and T. A. Hamilton. 1984. The cell biology of macrophage activation. Annu. Rev. Immunol. 2:283–318.
   PubMed Web of Science ®Google Scholar
• Boisclair, Y. R., A. L. Brown, S. Casola, and M. M. Rechler. 1993. Three clustered Sp1 sites are required for efficient transcription of the TATA-less promoter of the gene for insulin-like growth factor-binding protein-2 from the rat. J. Biol. Chem. 268:24892–24901.
   PubMedGoogle Scholar
• Borish, L., and B. Z. Joseph. 1992. Inflammation and the allergic response. Clin. Allergy 76:765–787.
   Google Scholar
• Caligaris-Cappio, F., G. Pizzolo, M. Chilosi, L. Bergui, C. Semenzato, L. Tesio, L. Morittu, F. Malavas, M. Gobbi, R. Schwarting, D. Campana, and G. Janossy. 1985. Phorbol ester induces abnormal chronic lymphocytic leukemia cells to express features of hairy cell leukemia. Blood 66:1035–1042.
   PubMed Web of Science ®Google Scholar
• Chadburn, A., G. Inghirami, and D. M. Knowles. 1990. Hairy cell leukemia-associated antigen LeuM5 (CD11c) is preferentially expressed by benign activated and neoplastic CD8 T cells. Am. J. Pathol. 136:29–37.
   PubMed Web of Science ®Google Scholar
• Chen, H.-M., H. L. Pahl, R. J. Scheibe, D.-E. Zhang, and D. G. Tenen. 1993. The Sp1 transcription factor binds the CD11b promoter specifically in myeloid cells in vivo and is essential for myeloid-specific promoter activity. J. Biol. Chem. 268:8230–8239.
   PubMed Web of Science ®Google Scholar
• Chen, X., K. L. Wright, E. A. Berkowitz, J. C. Azizkhan, J. P. Ting, and D. C. Lee. 1994. Protein interactions at Sp1-like sites in the TGF alpha promoter as visualized by in vivo genomic footprinting. Oncogene 9:3179–3187.
   PubMedGoogle Scholar
• Darrow, A. L., R. J. Rickles, L. T. Pecorino, and S. Strickland. 1990. Transcription factor Sp1 is important for retinoic acid-induced expression of the tissue plasminogen activator gene during F9 teratocarcinoma cell differentiation. Mol. Cell. Biol. 10:5883–5893.
   PubMedGoogle Scholar
• Ebert, S. N., and D. L. Wong. 1995. Differential activation of the rat phenylethanolamine N-methyltransferase gene by Sp1 and Egr-1. J. Biol. Chem. 270:17299–17305.
   PubMed Web of Science ®Google Scholar
• Fischer, A., B. Lisowska-Grospierre, D. C. Anderson, and T. A. Springer. 1988. The leukocyte adhesion deficiency: molecular basis and functional consequences. Immunodefic. Rev. 1:39–54.
   PubMedGoogle Scholar
• Fischer, K.-D., A. Haese, and J. Nowock. 1993. Cooperation of GATA-1 and Sp1 can result in synergistic transcriptional activation or interference. J. Biol. Chem. 268:23915–23923.
   PubMedGoogle Scholar
• Gashler, A. L., S. Swaminathan, and V. P. Sukhatme. 1993. A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the intermediate-early transcription factor Egr-1. Mol. Cell. Biol. 13:4556–4571.
   PubMedGoogle Scholar
• Gill, G., E. Pascal, Z. H. Tseng, and R. Tjian. 1994. A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc. Natl. Acad. Sci. USA 91:192–196.
   PubMed Web of Science ®Google Scholar
• Grant, L. 1973. The sticking and emigration of white blood cells in inflammation, p. 205–227. In B. Zweifach, L. Grant, and I. McCluskey (ed.), The inflammatory process. Academic Press, Orlando, Fla.
   Google Scholar
• Haas, J. G., M. Strobel, A. Leutz, P. Wendelga, C. Muller, E. Sterneck, G. Riethmuller, and H. W. L. Ziegler-Heitbrock. 1992. Constitutive monocyte restricted activity of NF-M: a nuclear factor that binds to a c/EBP motif. J. Immunol. 149:237–243.
   PubMedGoogle Scholar
• Hagen, G., S. Muller, M. Beato, and G. Suske. 1994. Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J. 13:3843–3851.
   PubMedGoogle Scholar
• Hromas, R., S. J. Collins, D. Hickstein, W. Raskind, L. L. Deaven, P. O'Hara, F. S. Hagen, and K. Kaushansky. 1991. A retinoic acid responsive human zinc finger gene, MZF-1, preferentially expressed in myeloid cells. J. Biol. Chem. 226:14183–14187.
   Google Scholar
• Jackson, S. P., J. J. MacDonald, S. Lees-Miller, and R. Tjian. 1990. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell 63:155–165.
   PubMed Web of Science ®Google Scholar
• Jackson, S. P., and R. Tjian. 1988. O-glycosylation of eucaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell 55:125–133.
   PubMed Web of Science ®Google Scholar
• Johnsrud, L. 1978. Contacts between Escherichia coli RNA polymerase and a lac operon promoter. Proc. Natl. Acad. Sci. USA 75:5314–5318.
   PubMed Web of Science ®Google Scholar
• Joseph, L. J., M. M. Lebeau, G. A. Jamieson, S. Acharya, T. B. Shows, J. D. Rowley, and V. P. Sukhatme. 1988. Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure. Proc. Natl. Acad. Sci. USA 85:7164–7168.
   PubMed Web of Science ®Google Scholar
• Keizer, G. D., J. Borst, W. Visser, R. Schwarting, J. E. De Vries, and C. G. Figdor. 1987. Membrane glycoprotein p150,95 of human cytotoxic T cell clones is involved in conjugate formation with target cells. J. Immunol. 138:3130–3136.
   PubMed Web of Science ®Google Scholar
• Keizer, G. D., A. A. te Velde, R. Schwarting, C. G. Figdor, and J. E. De Vries. 1987. Role of p150,95 in adhesion, migration, chemotaxis, and phagocytosis of human monocytes. Eur. J. Immunol. 17:1317–1322.
   PubMed Web of Science ®Google Scholar
• Kingsley, C., and A. Winoto. 1992. Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. Mol. Cell. Biol. 12:4251–4261.
   PubMedGoogle Scholar
• Kishimoto, T. K., R. S. Larson, A. L. Corbi, M. L. Dustin, D. E. Staunton, and T. A. Springer. 1989. The leukocyte integrins: LFA-1, Mac-1, and p150,95. Adv. Immunol. 46:149–182.
   PubMed Web of Science ®Google Scholar
• Krady, J. K., and D. C. Ward. 1995. Transcriptional activation by the parvoviral nonstructural protein NS-1 is mediated via a direct interaction with Sp1. Mol. Cell. Biol. 15:524–533.
   PubMedGoogle Scholar
• Kriwacki, R. W., S. C. Schultz, T. A. Steitz, and J. P. Caradonna. 1992. Sequence-specific recognition of DNA by zinc-finger peptides derived from the transcription factor Sp1. Proc. Natl. Acad. Sci. USA 89:9759–9763.
   PubMed Web of Science ®Google Scholar
• Larson, R. S., and T. A. Springer. 1990. Structure and function of the leukocyte integrins. Immunol. Rev. 114:181–216.
   PubMed Web of Science ®Google Scholar
• Lopez-Cabrera, M., A. Nueda, A. Vara, J. Garcia-Aguilar, A. Tugores, and A. Corbi. 1993. Characterization of the p150,95 leukocyte integrin alpha subunit (CD11c) gene promoter. J. Biol. Chem. 268:1187–1193.
   PubMed Web of Science ®Google Scholar
• Merika, M., and S. H. Orkin. 1995. Functional synergy and physical interactions of the erythroid transcriptional factor GATA-1 with the KrUppel family proteins Sp1 and EKLF. Mol. Cell. Biol. 15:2437–2447.
   PubMed Web of Science ®Google Scholar
• Molnar, G., A. Crozat, and A. B. Pardee. 1994. The immediate-early gene Egr-1 regulates the activity of the thymidine kinase promoter at the G0-to-G1 transition of the cell cycle. Mol. Cell. Biol. 14:5242–5248.
   PubMedGoogle Scholar
• Mueller, P. R., P. A. Garrity, and B. Wold. 1995. Ligation-mediated PCR for genomic sequencing and footprinting, p. 15.5.1–15.5.26. In F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.), Current protocols in molecular biology. Greene Publishing and Wiley Interscience, New York.
   Google Scholar
• Nathan, C., S. Srimall, C. Farber, E. Sanchez, L. Kabbash, A. Asch, J. Gailit, and S. D. Wright. 1989. Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins. J. Cell Biol. 116:1007–1017.
   Google Scholar
• Noti, J. D., M. Gordon, and R. E. Hall. 1992. Humanp150,95 alpha-subunit: genomic organization and analysis of the 5′-flanking region. DNA Cell Biol. 11:123–138.
   PubMedGoogle Scholar
• Noti, J. D., and B. C. Reinemann. 1995. The leukocyte integrin gene CD11c is transcriptionally regulated during monocyte differentiation. Mol. Immunol. 32:361–369.
   PubMed Web of Science ®Google Scholar
• Noti, J. D., B. C. Reinemann, and M. N. Petrus. Regulation of the leukocyte integrin gene CD11c is mediated by AP1 and Ets transcription factors. Mol. Immunol., in press.
   Google Scholar
• Osborn, L. 1990. Leukocyte adhesion to endothelium in inflammation. Cell 62:3–6.
   PubMed Web of Science ®Google Scholar
• Pahl, H., A. G. Rosmarin, and D. G. Tenen. 1992. Characterization of the myeloid-specific CD11b promoter. Blood 79:865–870.
   PubMedGoogle Scholar
• Pahl, H. L., R. J. Scheibe, D.-E. Zhang, H.-M. Chen, D. L. Galson, R. A. Maki, and D. G. Tenen. 1993. The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter. J. Biol. Chem. 268:5014–5020.
   PubMed Web of Science ®Google Scholar
• Patwardhan, S., A. Gashler, M. G. Siegel, L. C. Chang, L. J. Joseph, T. B. Shows, M. M. LeBeau, and V. P. Sukhatme. 1991. EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors. Oncogene 6:917–928.
   PubMed Web of Science ®Google Scholar
• Perez, C., E. Coeffier, F. Moreau-Gachelin, J. Wietzerbin, and P. D. Benech. 1994. Involvement of the transcription factor PU.1/Sp-1 in myeloid cell-restricted expression of an interferon-inducible gene encoding the human high-affinity Fcγ receptor. Mol. Cell. Biol. 14:5023–5031.
   PubMedGoogle Scholar
• Ray, D., R. Bosselut, J. Ghysdael, M.-G. Mattei, A. Tavitian, and F. Moreau-Gachelin. 1992. Characterization of Spi-B, a transcription factor related to the putative oncoprotein Sp1/PU.1. Mol. Cell. Biol. 12:4297–4304.
   PubMedGoogle Scholar
• Richard-Foy, H., and G. L. Hager. 1987. Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter. EMBO J. 6:2321–2328.
   PubMed Web of Science ®Google Scholar
• Rigaud, G., J. Roux, R. Pictet, and T. Grange. 1991. In vivo footprinting of the rat TAT gene: dynamic interplay between the glucocorticoid receptor and a liver-specific factor. Cell 67:977–986.
   PubMed Web of Science ®Google Scholar
• Rosmarin, A. G., S. C. Weil, G. L. Rosner, J. D. Griffin, M. A. Arnaout, and D. G. Tenen. 1989. Differential expression of CD11b/CD18 (Mol) and myeloperoxidase genes during myeloid differentiation. Blood 73:131–136.
   PubMed Web of Science ®Google Scholar
• Schaufele, F., B. L. West, and T. L. Reudelhuber. 1990. Overlapping Pit-1 and Sp1 binding sites are both essential to full rat growth hormone gene promoter activity despite mutually exclusive Pit-1 and Sp1 binding. J. Biol. Chem. 265:17189–17196.
   PubMed Web of Science ®Google Scholar
• Springer, T., G. Galfre, D. S. Secher, and C. Milstein. 1979. Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immun. 9:301–306.
   PubMed Web of Science ®Google Scholar
• Springer, T. A., L. J. Miller, and D. C. Anderson. 1986. P150,95, the third member of the Mac-1, LFA-1 human leukocyte adhesion glycoprotein family. J. Immunol. 136:230–245.
   PubMedGoogle Scholar
• Sukhatme, V. P., X. Cao, L. C. Chang, C.-H. Tsai-Morris, D. Stamenkovich, P. C. P. Ferreira, D. R. Cohen, S. A. Edwards, T. B. Shows, T. Curran, M. M. LeBeau, and E. D. Adamson. 1988. A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell 53:37–43.
   PubMed Web of Science ®Google Scholar
• Yu, C.-Y., J. Chen, L.-I. Lin, M. Tam, and C.-K. J. Shen. 1990. Cell type-specific protein-DNA interactions in the human ζ-globin upstream promoter region: displacement of Sp1 by the erythroid cell-specific factor NF-E1. Mol. Cell. Biol. 10:282–294.
   PubMedGoogle Scholar
• Zhang, D.-E., C. J. Hetherington, H.-M. Chen, and D. G. Tenen. 1994. The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor. Mol. Cell. Biol. 14:373–381.
   PubMedGoogle Scholar