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Research Article

Lack of Gene- and Strand-Specific DNA Repair in RNA Polymerase III-Transcribed Human tRNA Genes

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Pages 219-229 | Received 03 Jul 1996, Accepted 11 Oct 1996, Published online: 29 Mar 2023

REFERENCES

  • Armstrong, J. D., and B. A. Kunz. 1990. Site and strand specificity of UVB mutagenesis in the SUP4-o gene of yeast. Proc. Natl. Acad. Sci. USA 87:9005–9009.
  • Armstrong, J. D., and B. A. Kunz. 1992. Excision repair influences the site and strand specificity of sunlight mutagenesis in yeast. Mutat. Res. 274:123–133.
  • Bohr, V. A. 1988. DNA repair and transcriptional activity in genes. J. Cell Sci. 90:175–178.
  • Bohr, V. A., D. S. Okumoto, and P. C. Hanawalt. 1986. Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene. Proc. Natl. Acad. Sci. USA 83:3830–3833.
  • Bohr, V. A., C. A. Smith, D. S. Okumoto, and P. C. Hanawalt. 1985. DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell 40:359–369.
  • Brash, D. E. 1988. UV mutagenic photoproducts in Escherichia coli and human cells: a molecular genetics perspective on human skin cancer. Pho-tochem. Photobiol. 48:59–66.
  • Brash, D. E., S. Seetharam, K. H. Kraemer, M. M. Seidman, and A. Bredberg. 1987. Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells. Proc. Natl. Acad. Sci. USA 84:3782–3786.
  • Charbon, P., and A. Krol. 1991. Transcription of the Xenopus leavis seleno-cysteine tRNA(Ser)Sec gene: a system that combines an internal B box and upstream elements also found in U6 snRNA genes. EMBO J. 10:599–606.
  • Christians, F. C., and P. C. Hanawalt. 1993. Lack of transcription-coupled repair in mammalian ribosomal RNA genes. Biochemistry 32:10512–10518.
  • Clarke, E. M., C. L. Peterson, A. V. Brainard, and D. L. Riggs. 1996. Regulation of the RNA polymerase I and III transcription systems in response to growth conditions. J. Biol. Chem. 271:22189–22195.
  • Craig, L. C., L. P. Wang, M. M. Lee, I. L. Pirtle, and R. M. Pirtle. 1989. A human tRNA gene cluster encoding the major and minor valine tRNAs and a lysine tRNA. DNA 8:457–471.
  • Dammann, R., and G. P. Pfeifer. 1996. Unpublished results.
  • Dieci, G., and A. Sentenac. 1996. Facilitated recycling pathway for RNA polymerase III. Cell 84:245–252.
  • Drapkin, R., J. T. Reardon, A. Ansari, J. H. Huang, L. Zawel, K. Ahn, A. Sancar, and D. Reinberg. 1994. Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II. Nature 368:769–772.
  • Fritz, L. K., and M. J. Smerdon. 1995. Repair of UV damage in actively transcribed ribosomal genes. Biochemistry 34:13117–13124.
  • Gao, S., R. Drouin, and G. P. Holmquist. 1994. DNA repair rates mapped along the human PGK-1 gene at nucleotide resolution. Science 263:1438–1440.
  • Geiduschek, E. P., and G. A. Kassavetis. 1992. RNA polymerase III transcription complexes, p. 247–280. In K. Yamamoto and S. L. McKnight (ed.), Transcriptional regulation. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Geiduschek, E. P., and G. A. Kassavetis. 1995. Comparing transcriptional initiation by RNA polymerases I and III. Curr. Opin. Cell Biol. 7:344–351.
  • Geiduschek, E. P., and G. P. Tocchini-Valentini. 1988. Transcription by RNA polymerase III. Annu. Rev. Biochem. 57:873–914.
  • Hanawalt, P. C., B. A. Donahue, and K. S. Sweder. 1994. Repair and transcription. Collision or collusion?. Curr. Biol. 4:518–521.
  • Heider, J., W. Leinfelder, and A. Böck. 1989. Occurrence and functional compatibility within Enterobactriaceae of a tRNA species which inserts selenocysteine into protein. Nucleic Acids Res. 17:2529–2540.
  • Hernandez, N. 1992. Transcription of vertebrate snRNA genes and related genes, p. 281–313. In K. Yamamoto and S. L. McKnight (ed.), Transcrip-tional regulation. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Huet, J., and A. Sentenac. 1992. The TATA binding protein participates in TFIIIB assembly on tRNA genes. Nucleic Acids Res. 20:6451–6454.
  • Joazeiro, C. A. P., G. A. Kassavetis, and E. P. Geiduschek. 1996. Alternative outcomes in assembly of promoter complexes: the roles of TBP and a flexible linker in placing TFIIIB on tRNA genes. Genes Dev. 10:725–739.
  • Johnson, L. F., H. T. Abelson, H. Green, and S. Penman. 1974. Changes in RNA in relation to growth of the fibroblast. I. Amounts of mRNA, rRNA, and tRNA in resting and growing cells. Cell 1:95–100.
  • Kantor, G. J., and R. B. Setlow. 1981. Rate and extent of DNA repair in nondividing human diploid fibroblasts. Cancer Res. 41:819–825.
  • Lee, B. J., M. Rajagopalan, Y. S. Kim, K. H. You, K. B. Jacobson, and D. Hatfield. 1990. Selenocysteine-tRNA(Ser)Sec gene is ubiquitous within the animal kingdom. Mol. Cell. Biol. 10:1940–1949.
  • Lee, B. J., P. J. Worland, J. N. Davis, T. C. Stadtman, and D. L. Hatfield. 1989. Identification of a selenocysteyl-tRNASer in mammalian cells that recognizes the nonsense codon, UGA. J. Biol. Chem. 264:9724–9727.
  • Leinfelder, W., E. Zehelein, M.-A. Mandrand-Berthelot, and A. Bock. 1988. Gene for a novel tRNA species that accepts L-serine and cotranslationally inserts selenocysteine. Nature 331:723–725.
  • Low, S. C., and M. J. Berry. 1996. Knowing when to stop: selenocysteine incorporation in eukaryotes. Trends Biochem. Sci. 21:203–208.
  • Mauck, J. C., and H. Green. 1974. Regulation of pre-transfer RNA synthesis during transition from resting to growing state. Cell 3:171–177.
  • Maxam, A. M., and W. Gilbert. 1980. Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 65:499–560.
  • McBride, O. W., M. Rajagopalan, and D. Hatfield. 1987. Opal suppressor phosphoserine tRNA gene and pseudogene are located on human chromosomes 19 and 22, respectively. J. Biol. Chem. 262:11163–11166.
  • Mellon, I., G. Spivak, and P. C. Hanawalt. 1987. Selective removal of transcription blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell 51:241–249.
  • Mitchell, D. L., and R. S. Nairn. 1989. The biology of the (6-4) photoproduct. Photochem. Photobiol. 49:805–819.
  • Myslinski, E., C. Schuster, J. Huet, A. Sentenac, A. Krol, and P. Carbon. 1993. Point mutations 5′ to the tRNA selenocysteine TATA box alter RNA polymerase III transcription by affecting the binding of TBP. Nucleic Acids Res. 21:5852–5858.
  • O’Neill, G. P., and D. Söll. 1990. Expression of the Synechocystis sp. strain PCC 6803 tRNAGlu gene provides tRNA for protein and chlorophyll biosynthesis. J. Bacteriol. 172:6363–6371.
  • O’Neill, V. A., F. C. Eden, K. Pratt, and D. L. Hatfield. 1985. A human opal suppressor tRNA gene and pseudogene. J. Biol. Chem. 260:2501–2508.
  • Pfeifer, G. P., R. Drouin, and G. P. Holmquist. 1993. Detection of DNA adducts at the DNA sequence level by ligation-mediated PCR. Mutat. Res. 288:39–46.
  • Pfeifer, G. P., R. Drouin, A. D. Riggs, and G. P. Holmquist. 1991. In vivo mapping of a DNA adduct at nucleotide resolution: detection of pyrimidine (6-4) pyrimidone photoproducts by ligation-mediated polymerase chain reaction. Proc. Natl. Acad. Sci. USA 88:1374–1378.
  • Pfeifer, G. P., R. Drouin, A. D. Riggs, and G. P. Holmquist. 1992. Bindingof transcription factors creates hot spots for UV photoproducts in vivo. Mol. Cell. Biol. 12:1798–1804.
  • Pfeifer, G. P., J. Singer-Sam, and A. D. Riggs. 1993. PCR assays for meth-ylation and chromatin structure. Methods Enzymol. 225:567–583.
  • Rychlik, W., and R. E. Rhoads. 1989. A computer program for choosing optimal oligonucleotides for filter hybridization, sequencing and in vitro amplification of DNA. Nucleic Acids Res. 17:8543–8551.
  • Sage, E. 1993. Distribution and repair of photolesions in DNA: genetic consequences and the role of sequence context. Photochem. Photobiol. 57:163–174.
  • Saluz, H. P., and J.-P. Jost. 1993. Approaches to characterize protein-DNA interactions in vivo. Crit. Rev. Eukaryot. Gene Expression 3:1–29.
  • Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Schaeffer, L., R. Roy, S. Humbert, V. Moncollin, W. Vermeulen, J. H. J. Hoeijmakers, P. Chambon, and J. M. Egly. 1993. DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. Science 260:58–63.
  • Schmutzler, C., and H. J. Gross. 1990. Genes, variant genes, and pseudo-genes of the human tRNAVal gene family are differentially expressed in HeLa cells and in human placenta. Nucleic Acids Res. 18:5001–5008.
  • Seetharam, S., K. H. Kraemer, H. L. Waters, and M. M. Seidman. 1991. Ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum lymphoblastoid cells and fibroblasts. Mutat. Res. 254:97–105.
  • Selby, C. P., and A. Sancar. 1993. Molecular mechanism of transcription-repair coupling. Science 260:53–58.
  • Selby, C. P., and A. Sancar. 1994. Mechanisms of transcription-repair coupling and mutation frequency decline. Microbiol. Rev. 58:317–329.
  • Shortridge, R. D., G. D. Johnson, L. C. Craig, I. L. Pirtle, and R. M. Pirtle. 1989. A human tRNA gene heterocluster encoding threonine, proline and valine tRNAs. Gene 79:309–324.
  • Smerdon, M. J. 1991. DNA repair and the role of chromatin structure. Curr. Opin. Cell Biol. 3:422–128.
  • Sprague, K. U. 1992. New twists in class III transcription. Curr. Opin. Cell Biol. 4:475–479.
  • Stevnsner, T., A. May, L. N. Petersen, F. Larminat, M. Pirsel, and V. A. Bohr. 1993. Repair of ribosomal RNA genes in hamster cells after UV irradiation, or treatment with cisplatin or alkylating agents. Carcinogenesis 14:1519–1596.
  • Thomann, H.-U., C. Schmutzler, U. Hüdepohl, M. Blow, and H. J. Gross. 1989. Genes, variant genes and pseudogenes of the human tRNAVal gene family. Expression and pre-tRNA maturation in vitro. J. Mol. Biol. 209:505–523.
  • Tommasi, S., and G. P. Pfeifer. 1995. In vivo structure of the human cdc2 promoter: release of the p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression. Mol. Cell. Biol. 15:6901–6913.
  • Tüormaünen, V. T., and G. P. Pfeifer. 1992. Mapping of UV photoproducts within ras protooncogenes in UV-irradiated cells: correlation with mutations in human skin cancer. Oncogene 7:1729–1736.
  • Tornaletti, S., and G. P. Pfeifer. 1994. Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer. Science 263:1436–1438.
  • Tornaletti, S., and G. P. Pfeifer. 1995. UV-light as a footprinting agent: modulation of UV-induced DNA damage by transcription factors bound at the promoters of three human genes. J. Mol. Biol. 249:714–728.
  • Tornaletti, S., and G. P. Pfeifer. 1996. UV damage and repair mechanisms in mammalian cells. Bioessays 18:221–228.
  • Tornaletti, S., and G. P. Pfeifer. 1996. Ligation-mediated PCR for analysis of UV damage, p. 199–209. In G. P. Pfeifer (ed.), Technologies for detection of DNA damage and mutations. Plenum Press, New York, N.Y.
  • Troelstra, C., A. van Gool, J. de Wit, W. Vermeulen, D. Bootsma, and J. H. Hoijmakers. 1992. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne’s syndrome and preferential repair of active genes. Cell 71:939–953.
  • Tu, Y., S. Tornaletti, and G. P. Pfeifer. 1996. DNA repair domains within a human gene: selective repair of sequences near the transcription initiation site. EMBO J. 15:675–683.
  • van Hoffen, A., J. Venema, R. Meschini, A. A. van Zeeland, and L. H. F. Mullenders. 1995. Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts. EMBO J. 14:360–367.
  • Verhage, R. A., P. van de Putte, and J. Brouwer. 1996. Repair of rDNA in Saccharomyces cerevisiae: RAD4-independent strand-specific nucleotide excision repair of RNA polymerase I transcribed genes. Nucleic Acids Res. 24:1020–1025.
  • Vos, J.-M., and E. L. Wauthier. 1991. Differential introduction of DNA damage and repair in mammalian genes transcribed by RNA polymerase I and II. Mol. Cell. Biol. 11:2245–2252.
  • Vrieling, H., M. L. van Rooijen, N. A. Groen, M. Z. Zdzienicka, J. W. Simons, P. H. M. Lohman, and A. A. van Zeeland. 1989. DNA strand specificity for UV-induced mutations in mammalian cells. Mol. Cell. Biol. 9:1277–1283.
  • White, R. J., T. M. Gottlieb, C. S. Downes, and S. P. Jackson. 1995. Cell cycle regulation of RNA polymerase III transcription. Mol. Cell. Biol. 15:6653–6662.
  • Willis, I. M. 1993. RNA polymerase III: genes, factors and transcriptional specificity. Eur. J. Biochem. 212:1–11.
  • Wright, S., and J. M. Bishop. 1989. DNA sequences that mediate attenuation of transcription from the mouse protooncogene myc. Proc. Natl. Acad. Sci. USA 86:505–509.

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