Antagonism between Nur77 and Glucocorticoid Receptor for Control of Transcription

REFERENCES

• Auphan, N., J. A. DiDonato, C. Rosette, A. Helmberg, and M. Karin. 1995. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270:286–290.
   PubMed Web of Science ®Google Scholar
• Boutillier, A. L., D. Monnier, D. Lorang, J. R. Lundblad, J. L. Roberts, and J. P. Loeffler. 1995. Corticotropin-releasing hormone stimulates proopiomelanocortin transcription by cFos-dependent and -independent pathways: characterization of an AP1 site in exon 1. Mol. Endocrinol. 9:745–755.
   PubMed Web of Science ®Google Scholar
• Caldenhoven, E., J. Liden, S. Wissink, A. Van de Stolpe, J. Raaijmakers, L. Koenderman, S. Okret, J. A. Gustafsson, and P. T. van der Saag. 1995. Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids. Mol. Endocrinol. 9:401–412.
   PubMedGoogle Scholar
• Calnan, B. J., S. Szychowski, F. K. Chan, D. Cado, and A. Winoto. 1995. A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection. Immunity 3:273–282.
   PubMedGoogle Scholar
• Cheng, L. E. C., F. K. M. Chan, D. Cado, and A. Winoto. 1997. Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis. EMBO J. 16:1865–1875.
   PubMedGoogle Scholar
• Davis, I. J., and L. F. Lau. 1994. Endocrine and neurogenic regulation of the orphan nuclear receptors Nur77 and Nurr-1 in the adrenal glands. Mol. Cell. Biol. 14:3469–3483.
   PubMed Web of Science ®Google Scholar
• Drouin, J. 1993. Repression of transcription by nuclear receptors, p. 118–140. In M. G. Parker (ed.), Frontiers in molecular biology: steroid hormone action. Oxford University Press, Oxford, England.
   Google Scholar
• Drouin, J., and F. Labrie. 1976. Selective effect of androgens on LH and FSH release in anterior pituitary cells in culture. Endocrinology 98:1528–1534.
   PubMedGoogle Scholar
• Drouin, J., Y. L. Sun, M. Chamberland, Y. Gauthier, A. De Léan, M. Nemer, and T. J. Schmidt. 1993. Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene. EMBO J. 12:145–156.
   PubMed Web of Science ®Google Scholar
• Drouin, J., Y. L. Sun, S. Tremblay, P. Lavender, T. J. Schmidt, A. De Léan, and M. Nemer. 1992. Homodimer formation is rate-limiting for high affinity DNA binding by glucocorticoid receptor. Mol. Endocrinol. 6:1299–1309.
   PubMed Web of Science ®Google Scholar
• Drouin, J., M. A. Trifiro, R. K. Plante, M. Nemer, P. Eriksson, and Ö. Wrange. 1989. Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription. Mol. Cell. Biol. 9:5305–5314.
   PubMed Web of Science ®Google Scholar
• Eberwine, J. H., and J. L. Roberts. 1984. Glucocorticoid regulation of proopiomelanocortin gene transcription in the rat pituitary. J. Biol. Chem. 259:2166–2170.
   PubMedGoogle Scholar
• Egan, C. R., M. A. Chung, F. L. Allen, M. F. Heschl, C. L. Van Buskirk, and J. D. McGhee. 1995. A gut-to-pharynx/tail switch in embryonic expression of the Caenorhabditis elegans ges-1 gene centers on two GATA sequences. Dev. Biol. 170:397–419.
   PubMedGoogle Scholar
• Gagner, J.-P., and J. Drouin. 1985. Opposite regulation of pro-opiomelanocortin gene transcription by glucocorticoids and CRH. Mol. Cell. Endocrinol. 40:25–32.
   PubMed Web of Science ®Google Scholar
• Gagner, J.-P., and J. Drouin. 1987. Tissue-specific regulation of pituitary proopiomelanocortin gene transcription by corticotropin-releasing hormone, 3′,5′-cyclic adenosine monophosphate, and glucocorticoids. Mol. Endocrinol. 1:677–682.
   PubMedGoogle Scholar
• Godowski, P. J., S. Rusconi, R. Miesfeld, and K. R. Yamamoto. 1987. Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement. Nature 325:365–368.
   PubMed Web of Science ®Google Scholar
• Heck, S., M. Kullmann, A. Gast, H. Ponta, H. J. Rahmsdorf, P. Herrlich, and A. C. Cato. 1994. A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. EMBO J. 13:4087–4095.
   PubMed Web of Science ®Google Scholar
• Heinzel, T., R. M. Lavinsky, T. M. Mullen, M. Soderstrom, C. D. Laherty, J. Torchia, W. M. Yang, G. Brard, S. D. Ngo, J. R. Davie, E. Seto, R. N. Eisenman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1997. A complex containing N-Cor, mSin3 and histone deacetylase mediates transcriptional repression. Nature 387:43–48.
   PubMed Web of Science ®Google Scholar
• Helmberg, A., N. Auphan, C. Caelles, and M. Karin. 1995. Glucocorticoidinduced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor. EMBO J. 14:452–460.
   PubMed Web of Science ®Google Scholar
• Honkaniemi, J., J. Kononen, T. Kainu, I. Pyykonen, and M. Pelto-Huikko. 1994. Induction of multiple immediate early genes in rat hypothalamic paraventricular nucleus after stress. Brain Res. 25:234–241.
   Google Scholar
• Horlein, A. J., A. M. Naar, T. Heinzel, J. Torchia, B. Gloss, R. Kurokawa, A. Ryan, Y. Kamei, M. Soderstrom, C. K. Glass et al. 1995. Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 377:397–404.
   PubMed Web of Science ®Google Scholar
• Iwata, M., S. Hanaoka, and K. Sato. 1991. Rescue of thymocytes and T cell hybridomas from glucocorticoid-induced apoptosis by stimulation via the T cell receptor/CD3 complex: a possible in vitro model for positive selection of the T cell repertoire. Eur. J. Pharmacol. 21:643–648.
   Google Scholar
• Jacobson, L., and J. Drouin. 1994. Regulation of proopiomelanocortin gene transcription, p. 117–138. In H. Imura (ed.), The pituitary gland. Raven Press, New York, N.Y.
   Google Scholar
• Jonat, C., H. J. Rahmsdorf, K.-K. Park, A. C. B. Cato, S. Gebel, H. Ponta, and P. Herrlich. 1990. Antitumor promotion and antiinflammation: downmodulation of AP-1 (fos/jun) activity by glucocorticoid hormone. Cell 62:1189–1204.
   PubMed Web of Science ®Google Scholar
• Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S. C. Lin, R. A. Heyman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403–414.
   PubMed Web of Science ®Google Scholar
• Kerppola, T. K., D. Luk, and T. Curran. 1993. Fos is a preferential target of glucocorticoid receptor inhibition of AP-1 activity in vitro. Mol. Cell. Biol. 13:3782–3791.
   PubMed Web of Science ®Google Scholar
• King, L. B., M. S. Vacchio, and J. D. Ashwell. 1994. To be or not to be: mutually antagonistic death signals regulate thymocyte apoptosis. Int. Arch. Allergy Immunol. 105:355–358.
   PubMedGoogle Scholar
• King, L. B., M. S. Vacchio, K. Dixon, R. Hunziker, D. H. Margulies, and J. D. Ashwell. 1995. A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development. Immunity 3:647–656.
   PubMed Web of Science ®Google Scholar
• König, H., H. Ponta, H. J. Rahmsdorf, and P. Herrlich. 1992. Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo. EMBO J. 11:2241–2246.
   PubMed Web of Science ®Google Scholar
• Lamonerie, T., J. J. Tremblay, C. Lanctôt, M. Therrien, Y. Gauthier, and J. Drouin. 1996. PTX1, a bicoid-related homeobox transcription factor involved in transcription of pro-opiomelanocortin (POMC) gene. Genes Dev. 10:1284–1295.
   PubMed Web of Science ®Google Scholar
• Liu, Z. G., S. W. Smith, K. A. McLaughlin, L. M. Schwartz, and B. A. Osborne. 1994. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. Nature 367:281–284.
   PubMedGoogle Scholar
• Murphy, E. P., and O. M. Conneely. 1997. Neuroendocrine regulation of the hypothalamic pituitary adrenal axis by the nurr1/nur77 subfamily of nuclear receptors. Mol. Endocrinol. 11:39–47.
   PubMed Web of Science ®Google Scholar
• Nagy, L., H. Y. Kao, D. Chakravarti, R. J. Lin, C. A. Hassig, D. E. Ayer, S. L. Schreiber, and R. M. Evans. 1997. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 89:373–380.
   PubMed Web of Science ®Google Scholar
• Onate, S. A., S. Y. Tsai, M. J. Tsai, and B. W. O’Malley. 1995. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354–1357.
   PubMed Web of Science ®Google Scholar
• Parkes, D., S. Rivest, S. Lee, C. Rivier, and W. Vale. 1993. Corticotropinreleasing factor activates c-fos, NGFI-B, and corticotropin-releasing factor gene expression within the paraventricular nucleus of the rat hypothalamus. Mol. Endocrinol. 7:1357–1367.
   PubMedGoogle Scholar
• Philips, A., S. Lesage, R. Gingras, M.-H. Maira, Y. Gauthier, P. Hugo, and J. Drouin. 1997. Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells. Mol. Cell. Biol. 17:5946–5951.
   PubMed Web of Science ®Google Scholar
• Poulin, G., B. Turgeon, and J. Drouin. NeuroD1/BETA2 contributes to cell-specific transcription of the POMC gene. Mol. Cell. Biol., in press.
   Google Scholar
• Riegel, A. T., Y. Lu, J. Remenick, R. G. Wolford, D. S. Berard, and G. L. Hager. 1991. Proopiomelanocortin gene promoter elements required for constitutive and glucocorticoid-repressed transcription. Mol. Endocrinol. 5:1973–1982.
   PubMedGoogle Scholar
• Scheinman, R. I., P. C. Cogswell, A. K. Lofquist, and A. S. Baldwin, Jr. 1995. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270:283–286.
   PubMed Web of Science ®Google Scholar
• Scheinman, R. I., A. Gualberto, C. M. Jewell, J. A. Cidlowski, and A. S. Baldwin, Jr. 1995. Characterization of mechanisms involved in transrepression of NF-nB by activated glucocorticoid receptors. Mol. Cell. Biol. 15:943–953.
   PubMed Web of Science ®Google Scholar
• Schüle, R., P. Rangarajan, S. Kliewer, L. J. Ransone, J. Bolado, N. Yang, I. M. Verma, and R. M. Evans. 1990. Functional antagonism between oncoprotein c-jun and the glucocorticoid receptor. Cell 62:1217–1226.
   PubMed Web of Science ®Google Scholar
• Sgonc, R., G. Boeck, H. Dietrich, J. Gruber, H. Recheis, and G. Wick. 1994. Simultaneous determination of cell surface antigens and apoptosis. Trends Genet. 10:41–42.
   PubMed Web of Science ®Google Scholar
• Therrien, M., and J. Drouin. 1991. Pituitary pro-opiomelanocortin gene expression requires synergistic interactions of several regulatory elements. Mol. Cell. Biol. 11:3492–3503.
   PubMedGoogle Scholar
• Therrien, M., and J. Drouin. 1993. Cell-specific helix-loop-helix factor required for pituitary expression of the pro-opiomelanocortin gene. Mol. Cell. Biol. 13:2342–2353.
   PubMedGoogle Scholar
• Wilson, T. E., T. J. Fahrner, M. Johnston, and J. Milbrandt. 1991. Identification of the DNA binding site for NGFI-B by genetic selection in yeast. Science 252:1296–1300.
   PubMed Web of Science ®Google Scholar
• Wolffe, A. P. 1997. Transcriptional control—sinful repression. Nature 387:16–17.
   PubMed Web of Science ®Google Scholar
• Woronicz, J. D., B. Calnan, V. Ngo, and A. Winoto. 1994. Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas. Nature 367:277–281.
   PubMedGoogle Scholar
• Yang-Yen, H. F., J. C. Chambard, Y. L. Sun, T. Smeal, T. J. Schmidt, J. Drouin, and M. Karin. 1990. Transcriptional interference between c-jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62:1205–1215.
   PubMed Web of Science ®Google Scholar