17
Views
179
CrossRef citations to date
0
Altmetric
Research Article

O Glycosylation of an Sp1-Derived Peptide Blocks Known Sp1 Protein Interactions

, , &
Pages 6472-6480 | Received 24 Mar 1997, Accepted 27 Aug 1997, Published online: 29 Mar 2023

REFERENCES

  • Chou, T. Y., G. W. Hart, and C. V. Dang. 1995. c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas. J. Biol. Chem. 270:18961–18965.
  • Ciechanover, A. 1994. The ubiquitin-proteasome proteolytic pathway. Cell 79:13–21.
  • Courey, A. J., D. A. Holtzman, S. P. Jackson, and R. Tjian. 1989. Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell 59:827–836.
  • Courey, A. J., and R. Tjian. 1988. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell 55:887–898.
  • Cress, W. D., and S. J. Triezenburg. 1991. Critical structural elements of the VP16 transcriptional activation domain. Science 251:670–682.
  • Dong, D. L.-Y., and G. W. Hart. 1994. Purification and characterization of an O-GlcNAc selective N-acetyl-b-D-glucosaminidase from rat spleen cytosol. J. Biol. Chem. 269:19321–19330.
  • Ferreri, K., G. Gill, and M. Montminy. 1994. The cAMP-regulated transcription factor CREB interacts with a component of the TFIID complex. Proc. Natl. Acad. Sci. USA 9:1210–1213.
  • Gill, G., E. Pascal, Z. H. Tseng, and R. Tjian. 1994. A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc. Natl. Acad. Sci. USA 91:192–196.
  • Gill, G., and M. Ptashne. 1988. Negative effect of the transcriptional activator Gal4. Nature (London) 334:721–724.
  • Goodrich, J. A., T. Hoey, C. J. Thut, A. Admon, and R. Tjian. 1993. TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB. Cell 75:519–530.
  • Haltiwanger, R. S., M. A. Blomberg, and G. W. Hart. 1992. Glycosylation of nuclear and cytoplasmic proteins. J. Biol. Chem. 267:9005–9013.
  • Han, I., and J. E. Kudlow. 1997. Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility. Mol. Cell. Biol. 17:2550–2558.
  • Hart, G. W. 1997. Dynamic O-GlcNAcylation of nuclear and cytoskeletal proteins. Annu. Rev. Biochem. 66:315–335.
  • Hart, G. W., R. S. Haltiwanger, G. D. Holt, and W. G. Kelly. 1989. Glycosylation in the nucleus and cytoplasm. Annu. Rev. Biochem. 58:841–871.
  • Hoey, T., R. O. J. Weinzierl, G. Gill, J. L. Chen, B. D. Dynlacht, and R. Tjian. 1993. Molecular cloning and functional analysis of Drosophila TAF110 reveals properties expected of coactivators. Cell 72:247–260.
  • Holt, G. D., and G. W. Hart. 1986. The subcellular distribution of terminal N-acetylglucosamine moieties. J. Biol. Chem. 261:8049–8057.
  • Holt, G. D., C. M. Snow, A. Senior, R. S. Haltiwanger, L. Gerace, and G. W. Hart. 1987. Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine. J. Cell Biol. 104:1157–1164.
  • Jackson, S. P., J. J. MacDonald, S. Lees-Miller, and R. Tjian. 1990. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell 63:155–165.
  • Jackson, S. P., and R. Tjian. 1988. O-Glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell 55:125–133.
  • Kadonaga, J. T., A. J. Courey, J. Ladika, and R. Tjian. 1988. Distinct regions of Sp1 modulate DNA binding and transcriptional activation. Science 242:1566–1570.
  • Kearse, K. P., and G. W. Hart. 1991. Lymphocyte activation induces rapid changes in nuclear and cytoplasmic glycoproteins. Proc. Natl. Acad. Sci. USA 88:1701–1705.
  • Kelly, W. G., M. E. Dahmus, and G. W. Hart. 1993. RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc. J. Biol. Chem. 268:10416–10424.
  • Moss, B. 1991. Vaccinia virus: a tool for research and vaccine development. Science 252:1662–1667.
  • Pascal, E., and R. Tjian. 1991. Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev. 5:1646–1656.
  • Pugh, B. F., and R. Tjian. 1991. Transcription from a TATA-less promoter requires a multi-subunit TFIID complex. Genes Dev. 5:1935–1945.
  • Reason, A. J., H. R. Morris, M. Panico, R. Marais, R. H. Treisman, R. S. Haltiwanger, G. W. Hart, W. G. Kelly, and A. Dell. 1992. Localization of O-GlcNAc modification on the serum response transcription factor. J. Biol. Chem. 267:16911–16921.
  • Sauer, F., S. K. Hansen, and R. Tjian. 1995. DNA template and activator-coactivator requirements for transcriptional synergism by Drosophila Bicoid. Science 270:1825–1828.
  • Sauer, F., D. A. Wassarman, G. M. Rubin, and R. Tjian. 1996. TAFs mediate activation of transcription in the Drosophila embryo. Cell 87:1271–1284.
  • Schindler, M., M. Hogan, R. Miller, and D. DeGaetano. 1987. A nuclear specific glycoprotein representative of a unique pattern of glycosylation. J. Biol. Chem. 262:1254–1260.
  • Shin, T. H., and J. E. Kudlow. 1994. Identification and characterization of the human transforming growth factor a initiator. Mol. Endocrinol. 8:704–712.
  • Starr, C. M., and J. A. Hanover. 1990. Glycosylation of nuclear pore protein p62. Reticulocyte lysate catalyzes O-linked N-acetylglucosamine addition in vitro. J. Biol. Chem. 265:6868–6873.
  • Tanese, N., B. F. Pugh, and R. Tjian. 1991. Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex. Genes Dev. 5:2212–2224.
  • Torres, C., and G. W. Hart. 1984. Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surface of intact lymphocytes. J. Biol. Chem. 259:3308–3317.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.