REFERENCES
- Affolter, M., and A. Ruiz-Carrillo 1986. Transcription unit of the chicken histone H5 gene and mapping of H5 pre-mRNA sequences. J. Biol. Chem. 261: 11496–11502.
- Ashfield, R., P. Enriquez-Harris, and N. J. Proudfoot 1991. Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c-myc? EMBO J. 10: 4197–4207.
- Ashfield, R., A. J. Patel, S. A. Bossone, H. Brown, R. D. Campbell, K. B. Marcu, and N. J. Proudfoot 1994. MAZ-dependent termination between closely spaced human complement genes. EMBO J. 13: 5656–5667.
- Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl 1988. Current protocols in molecular biology. Wiley & Sons, New York, N.Y.
- Baker, C. C., and J. S. Noe 1989. Transcriptional termination between bovine papillomavirus type 1 (BPV-1) early and late polyadenylation sites blocks late transcription in BPV-1-transformed cells. J. Virol. 63: 3529–3534.
- Berget, S. M. 1995. Exon recognition in vertebrate splicing. J. Biol. Chem. 270: 2411–2414.
- Birse, C. E., B. A. Lee, K. Hansen, and N. J. Proudfoot 1997. Transcriptional termination signals for RNA polymerase II in fission yeast. EMBO J. 16: 3633–3643.
- Blau, J., H. Xiao, S. McCracken, P. O’Hare, J. Greenblatt, and D. Bentley 1996. Three functional classes of transcriptional activation domain. Mol. Cell. Biol. 16: 2044–2055.
- Carswell, S., and J. C. Alwine 1989. Efficiency of utilization of the simian virus 40 late polyadenylation site: effects of upstream sequences. Mol. Cell. Biol. 9: 4248–4258.
- Connelly, S., and J. L. Manley 1989. A CCAAT box sequence in the adenovirus major late promoter functions as part of an RNA polymerase II termination signal. Cell 57: 561–571.
- Connelly, S., and J. L. Manley 1988. A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II. Genes Dev. 2: 440–452.
- Connelly, S., and J. L. Manley 1989. RNA polymerase II transcription termination is mediated specifically by protein binding to a CCAAT box sequence. Mol. Cell. Biol. 9: 5254–5259.
- DeLucia, A. L., S. Deb, K. Partin, and P. Tegtmeyer 1986. Functional interactions of the simian virus 40 core origin of replication with flanking regulatory sequences. J. Virol. 57: 138–144.
- Dressler, G. R., and N. W. Fraser 1987. DNA sequences downstream of the adenovirus type 2 fiber polyadenylation site contain transcription termination signals. J. Virol. 61: 2770–2776.
- Edwalds-Gilbert, G., J. Prescott, and E. Falck-Pedersen 1993. 3′ RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes. Mol. Cell. Biol. 13: 3472–3480.
- Enriquez-Harris, P., N. Levitt, D. Briggs, and N. J. Proudfoot 1991. A pause site for RNA polymerase II is associated with termination of transcription. EMBO J. 10: 1833–1842.
- Flaspohler, J. A., D. Boczkowski, B. L. Hall, and C. Milcarek 1995. The 3′-untranslated region of membrane exon 2 from the γ2a immunoglobulin gene contributes to efficient transcription termination. J. Biol. Chem. 270: 11903–11911.
- Ford, J. P., and M. T. Hsu 1978. Transcription pattern of in vivo-labeled late simian virus 40 RNA: equimolar transcription beyond the mRNA 3′ terminus. J. Virol. 28: 795–801.
- Fraser, N. W., J. R. Nevins, E. Ziff, Darnell J. E., Jr. 1979. The major late adenovirus type-2 transcription unit: termination is downstream from the last poly(A) site. J. Mol. Biol. 129: 643–656.
- Frayne, E. G., E. J. Leys, G. F. Crouse, A. G. Hook, and R. E. Kellems 1984. Transcription of the mouse dihydrofolate reductase gene proceeds unabated through seven polyadenylation sites and terminates near a region of repeated DNA. Mol. Cell. Biol. 4: 2921–2924.
- Fromm, M., and P. Berg 1982. Deletion mapping of DNA regions required for SV40 early region promoter function in vivo. J. Mol. Appl. Genet. 1: 457–481.
- Giardina, C., and J. T. Lis 1993. Polymerase processivity and termination on Drosophila heat shock genes. J. Biol. Chem. 268: 23806–23811.
- Gilmartin, G. M., S. L. Hung, J. D. DeZazzo, E. S. Fleming, and M. J. Imperiale 1996. Sequences regulating poly(A) site selection within the adenovirus major late transcription unit influence the interaction of constitutive processing factors with the pre-mRNA. J. Virol. 70: 1775–1783.
- Gorman, C. M., G. T. Merlino, M. C. Willingham, I. Pastan, and B. H. Howard 1982. The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc. Natl. Acad. Sci. USA 79: 6777–6781.
- Gorman, C. M., L. F. Moffat, and B. H. Howard 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2: 1044–1051.
- Gunderson, S. I., S. Vagner, M. Polycarpou-Schwarz, and I. W. Mattaj 1997. Involvement of the carboxyl terminus of vertebrate poly(A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation. Genes Dev. 11: 761–773.
- Hagenbüchle, O., P. K. Wellauer, D. L. Cribbs, and U. Schibler 1984. Termination of transcription in the mouse α-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site. Cell 38: 737–744.
- Hair, A., and G. T. Morgan 1993. Premature termination of tubulin gene transcription in Xenopus oocytes is due to promoter-dependent disruption of elongation. Mol. Cell. Biol. 13: 7925–7934.
- Iwamoto, S., F. Eggerding, E. Falck-Pederson, Darnell J. E., Jr. 1986. Transcription unit mapping in adenovirus: regions of termination. J. Virol. 59: 112–119.
- Kaufman, R. J. 1990. Vectors used for expression in mammalian cells. Methods Enzymol. 185: 487–511.
- Krumm, A., T. Meulia, M. Brunvand, and M. Groudine 1992. The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region. Genes Dev. 6: 2201–2213.
- Lanoix, J., and N. H. Acheson 1988. A rabbit β-globin polyadenylation signal directs efficient termination of transcription of polyomavirus DNA. EMBO J. 7: 2515–2522.
- Lee, J. M., and A. L. Greenleaf 1997. Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I. J. Biol. Chem. 272: 10990–10993.
- LeMeur, M. A., B. Galliot, and P. Gerlinger 1984. Termination of the ovalbumin gene transcription. EMBO J. 3: 2779–2786.
- Liu, D. H., and S. J. Kim. Unpublished data.
- Liu, X., and J. E. Mertz 1996. Sequence of the polypyrimidine tract of the 3′-terminal 3′ splicing signal can affect intron-dependent pre-mRNA processing in vivo. Nucleic Acids Res. 24: 1765–1773.
- Logan, J., E. Falck-Pedersen, Darnell J. E., Jr., and T. Shenk 1987. A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse βmaj-globin gene. Proc. Natl. Acad. Sci. USA 84: 8306–8310.
- London, L., R. G. Keene, and R. Landick 1991. Analysis of premature termination in c-myc during transcription by RNA polymerase II in a HeLa nuclear extract. Mol. Cell. Biol. 11: 4599–4615.
- Lou, H., R. F. Gagel, and S. M. Berget 1996. An intron enhancer recognized by splicing factors activates polyadenylation. Genes Dev. 10: 208–219.
- Maa, M. C., J. M. Chinsky, V. Ramamurthy, B. D. Martin, and R. E. Kellems 1990. Identification of transcription stop sites at the 5′ and 3′ ends of the murine adenosine deaminase gene. J. Biol. Chem. 265: 12513–12519.
- Maderious, A., and S. Chen-Kiang 1984. Pausing and premature termination of human RNA polymerase II during transcription of adenovirus in vivo and in vitro. Proc. Natl. Acad. Sci. USA 81: 5931–5935.
- McCracken, S., N. Fong, K. Yankulov, S. Ballantyne, G. Pan, J. Greenblatt, S. D. Patterson, M. Wickens, and D. L. Bentley 1997. The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. Nature 385: 357–361.
- Meulia, T., A. Krumm, and M. Groudine 1993. Distinct properties of c-myc transcriptional elongation are revealed in Xenopus oocytes and mammalian cells and by template titration, 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole (DRB), and promoter mutagenesis. Mol. Cell. Biol. 13: 5647–5658.
- Moore, B. B., J. Tan, P. L. Lim, P. W. Tucker, and D. Yuan 1993. Regulatory elements necessary for termination of transcription within the Ig heavy chain gene locus. Nucleic Acids Res. 21: 1481–1488.
- Nevins, J. R., Darnell, J. E.Jr. 1978. Steps in the processing of Ad2 mRNA: poly(A)+ nuclear sequences are conserved and poly(A) addition precedes splicing. Cell 15: 1477–1493.
- Nguyen, N. Unpublished data.
- Niwa, M., S. D. Rose, and S. M. Berget 1990. In vitro polyadenylation is stimulated by the presence of an upstream intron. Genes Dev. 4: 1552–1559.
- O’Brien, T., and J. T. Lis 1993. Rapid changes in Drosophila transcription after an instantaneous heat shock. Mol. Cell. Biol. 13: 3456–3463.
- Okamoto, H., C. T. Sheline, J. L. Corden, K. A. Jones, and B. M. Peterlin 1996. Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II. Proc. Natl. Acad. Sci. USA 93: 11575–11579.
- Parada, C. A., and R. G. Roeder 1996. Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. Nature 384: 375–378.
- Plet, A., D. Eick, and J. M. Blanchard 1995. Elongation and premature termination of transcripts initiated from c-fos and c-myc promoters show dissimilar patterns. Oncogene 10: 319–328.
- Pribyl, T. M., and H. G. Martinson 1988. Transcription termination at the chicken βH-globin gene. Mol. Cell. Biol. 8: 5369–5377.
- Proudfoot, N. J. 1989. How RNA polymerase II terminates transcription in higher eukaryotes. Trends Biochem. Sci. 14: 105–110.
- Rasmussen, E. B., and J. T. Lis 1995. Short transcripts of the ternary complex provide insight into RNA polymerase II elongational pausing. J. Mol. Biol. 252: 522–535.
- Roberts, S., and D. L. Bentley 1992. Distinct modes of transcription read through or terminate at the c-myc attenuator. EMBO J. 11: 1085–1093.
- Rohrbaugh, M. L., Johnson, J. E.III, M. D. James, and R. C. Hardison 1985. Transcription unit of the rabbit β1 globin gene. Mol. Cell. Biol. 5: 147–160.
- Sato, K., R. Ito, K. H. Baek, and K. Agarwal 1986. A specific DNA sequence controls termination of transcription in the gastrin gene. Mol. Cell. Biol. 6: 1032–1043.
- Sawadogo, M., and R. G. Roeder 1985. Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay. Proc. Natl. Acad. Sci. USA 82: 4394–4398.
- Southern, P. J., and P. Berg 1982. Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J. Mol. Appl. Genet. 1: 327–341.
- Strobl, L. J., and D. Eick 1992. Hold back of RNA polymerase II at the transcription start site mediates down-regulation of c-myc in vivo. EMBO J. 11: 3307–3314.
- Szentirmay, M. N., and M. Sawadogo 1991. Transcription factor requirement for multiple rounds of initiation by human RNA polymerase II. Proc. Natl. Acad. Sci. USA 88: 10691–10695.
- Tantravahi, J., M. Alvira, and E. Falck-Pedersen 1993. Characterization of the mouse βmaj globin transcription termination region: a spacing sequence is required between the poly(A) signal sequence and multiple downstream termination elements. Mol. Cell. Biol. 13: 578–587.
- Tisch, R., N. Kondo, and N. Hozumi 1990. Parameters that govern the regulation of immunoglobulin δ heavy-chain gene expression. Mol. Cell. Biol. 10: 5340–5348.
- Vandenbergh, D. J., M. James-Pederson, and R. C. Hardison 1991. An apparent pause site in the transcription unit of the rabbit α-globin gene. J. Mol. Biol. 220: 255–270.
- Villeponteau, B., G. M. Landes, M. J. Pankratz, and H. G. Martinson 1982. The chicken β globin gene region. Delineation of transcription units and developmental regulation of interspersed DNA repeats. J. Biol. Chem. 257: 11015–11023.
- Wassarman, K. M., and J. A. Steitz 1993. Association with terminal exons in pre-mRNAs: a new role for the U1 snRNP? Genes Dev. 7: 647–659.
- Weintraub, H., A. Larsen, and M. Groudine 1981. α-Globin-gene switching during the development of chicken embryos: expression and chromosome structure. Cell 24: 333–344.
- Whitelaw, E., and N. Proudfoot 1986. α-Thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3′ end processing in the human α2 globin gene. EMBO J. 5: 2915–2922.
- Williams, R. D., B. A. Lee, S. P. Jackson, and N. J. Proudfoot 1996. Activation domains of transcription factors mediate replication dependent transcription from a minimal HIV-1 promoter. Nucleic Acids Res. 24: 549–557.
- Xu, M., M. B. Barnard, S. M. Rose, P. N. Cockerill, S. Y. Huang, and W. T. Garrard 1986. Transcription termination and chromatin structure of the active immunoglobulin kappa gene locus. J. Biol. Chem. 261: 3838–3845.
- Yankulov, K. Y., M. Pandes, S. McCracken, D. Bouchard, and D. L. Bentley 1996. TFIIH functions in regulating transcriptional elongation by RNA polymerase II in Xenopus oocytes. Mol. Cell. Biol. 16: 3291–3299.