Cytomegalovirus Activates Interferon Immediate-Early Response Gene Expression and an Interferon Regulatory Factor 3-Containing Interferon-Stimulated Response Element-Binding Complex

REFERENCES

• Ackrill, A. M., G. R. Foster, C. D. Laxton, D. M. Flavell, G. R. Stark, and I. M. Kerr 1991. Inhibition of the cellular response to interferons by the products of the adenovirus type 5 E1A oncogene. Nucleic Acids Res. 19: 4387–4393.
   PubMed Web of Science ®Google Scholar
• Au, W.-C., P. A. Moore, W. Lowther, Y.-T. Juang, and P. M. Pitha 1995. Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes. Proc. Natl. Acad. Sci. USA 92: 11657–11661.
   PubMed Web of Science ®Google Scholar
• Bhattacharya, S., R. Eckner, S. Grossman, E. Oldread, Z. Arany, A. D’Andrea, and D. M. Livingston 1996. Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α. Nature 383: 344–347.
   PubMed Web of Science ®Google Scholar
• Bovelenta, C., J. Lou, Y. Kanno, B.-K. Park, A. M. Thornton, J. E. Colligan, M. Schubert, and K. Ozato 1995. Vesicular stomatitis virus infection induces a nuclear DNA-binding factor specific for the interferon-stimulated response element. J. Virol. 69: 4173–4181.
   PubMedGoogle Scholar
• Bromberg, J., C. Horvath, Z. Wen, R. Schreiber, and J. Darnell 1996. Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon α and interferon γ. Proc. Natl. Acad. Sci. USA 93: 7673–7678.
   PubMed Web of Science ®Google Scholar
• Cha, Y., and A. B. Deisseroth 1994. Human interferon regulatory factor 2 gene. Intron-exon organization and functional analysis of 5′-flanking region. J. Biol. Chem. 269: 5279–5287.
   PubMedGoogle Scholar
• Colamonici, O. R., P. Domanski, S. M. Sweitzer, A. Larner, and R. M. L. Buller 1995. Vaccinia virus B18R gene encodes a type 1 interferon-binding protein that blocks interferon α transmembrane signaling. J. Biol. Chem. 270: 15974–15978.
   PubMed Web of Science ®Google Scholar
• David, M. 1995. Transcription factors in interferon signaling. Pharmacol. Ther. 65: 149–161.
   PubMed Web of Science ®Google Scholar
• David, M., and A. C. Larner 1992. Activation of transcription factors by interferon alpha in a cell-free system. Science 257: 813–815.
   PubMed Web of Science ®Google Scholar
• David, M., G. Romero, Z. Y. Zhang, J. E. Dixon, and A. C. Larner 1993. In vitro activation of the transcription factor ISGF3 by IFNα involves a membrane-associated tyrosine phosphatase and kinase. J. Biol. Chem. 268: 6593–6599.
   PubMed Web of Science ®Google Scholar
• Durbin, J. E., R. Hackenmiller, M. C. Simon, and D. E. Levy 1996. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84: 443–450.
   PubMed Web of Science ®Google Scholar
• Finbloom, D. S., and A. C. Larner 1995. Induction of early response genes by interferons, interleukins, and growth factors by the tyrosine phosphorylation of latent transcription factors: implications for chronic inflammatory diseases. Arthritis Rheum. 38: 877–889.
   PubMedGoogle Scholar
• Fu, X.-Y. 1992. A transcription factor with SH2 and SH3 domains is directly activated by an interferon-α induced cytoplasmic protein tyrosine kinase(s). Cell 70: 323–335.
   PubMed Web of Science ®Google Scholar
• Fu, X.-Y., D. S. Kessler, S. A. Veals, D. E. Levy, Darnell J. E., Jr. 1990. ISGF-3, the transcriptional activator induced by IFN-α, consists of multiple interacting polypeptide chains. Proc. Natl. Acad. Sci. USA 87: 8555–8559.
   PubMed Web of Science ®Google Scholar
• Fu, X.-Y., C. Schindler, T. Improta, R. Aebersold, and J. E. J. Darnell 1992. The proteins of ISGF-3, the interferon α-induced transcriptional activator, define a gene family involved in signal transduction. Proc. Natl. Acad. Sci. USA 89: 7840–7843.
   PubMed Web of Science ®Google Scholar
• Fujita, T., Y. Kimura, M. Miyamoto, E. L. Barsoumian, and T. Taniguchi 1989. Induction of endogenous IFN-α and IFN-β genes by a regulatory transcription factor. Nature 337: 270–272.
   PubMed Web of Science ®Google Scholar
• Gutch, M., and N. Reich 1991. Repression of the interferon signal transduction pathway by the adenovirus E1A oncogene. Proc. Natl. Acad. Sci. USA 88: 7913–7917.
   PubMed Web of Science ®Google Scholar
• Gutch, M., and N. C. Reich 1991. Response of the interferon signal transduction pathway by the adenovirus E1A oncogene. Proc. Natl. Acad. Sci. USA 88: 7913–7917.
   PubMed Web of Science ®Google Scholar
• Harada, H., T. Fujita, M. Miyamoto, Y. Kimura, M. Maruyama, A. Furia, T. Miyata, and T. Taniguchi 1989. Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 58: 729–739.
   PubMed Web of Science ®Google Scholar
• Isaacs, A., and J. Lindenmann 1957. Virus interference: the interferon. Proc. R. Soc. Lond. Ser. B 147: 258–267.
   PubMed Web of Science ®Google Scholar
• Kalvakolanu, D. V. R., and G. C. Sen 1993. Differentiation-dependent activation of interferon-stimulated gene factors and transcription factor NF-κB in mouse embryonal carcinoma cells. Proc. Natl. Acad. Sci. USA 90: 3167–3171.
   PubMed Web of Science ®Google Scholar
• Kanno, Y., C. A. Kozak, C. Schindler, P. H. Driggers, D. L. Ennist, S. L. Gleason, J. E. J. Darnell, and K. Ozato 1993. The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3α subunit (or similar) molecule binds. Mol. Cell. Biol. 13: 3951–3963.
   PubMed Web of Science ®Google Scholar
• Kessler, D. S., S. A. Veals, X.-Y. Fu, and D. S. Levy 1990. Interferon-α regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. Genes Dev. 4: 1753–1765.
   PubMed Web of Science ®Google Scholar
• Khan, K. D., K. Shuai, G. Lindwall, S. E. Maher, J. E. J. Darnell, and A. L. M. Bothwell 1993. Induction of the Ly-6A/E gene by interferon α/β and γ requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds. Proc. Natl. Acad. Sci. USA 90: 6806–6810.
   PubMed Web of Science ®Google Scholar
• Larner, A. C., A. Chaudhuri, and J. E. Darnell 1986. Transcriptional induction by interferon: new protein(s) determine the extent and length of the induction. J. Biol. Chem. 261: 453–459.
   PubMed Web of Science ®Google Scholar
• Larner, A. C., G. Jonak, Y.-S. E. Cheng, B. Korant, E. Knight, and J. E. Darnell 1984. Transcriptional induction of two genes in human cells by β interferon. Proc. Natl. Acad. Sci. USA 81: 6733–6737.
   PubMed Web of Science ®Google Scholar
• Levy, D. E., D. S. Kessler, R. Pine, Darnell J. E., Jr. 1989. Cytoplasmic activation of ISGF3, the positive regulator of interferon-α-stimulated transcription, reconstituted in vitro. Genes Dev. 3: 1362–1371.
   PubMed Web of Science ®Google Scholar
• Levy, D. E., D. J. Lew, D. S. Kessler, Darnell J. E., Jr. 1990. Synergistic interaction between interferon-α and interferon-γ through induced synthesis of one subunit of the transcription factor ISGF3. EMBO J. 9: 1105–1111.
   PubMed Web of Science ®Google Scholar
• Luster, A. D., J. C. Unkeless, and J. V. Ravetch 1985. γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature 315: 672–676.
   PubMed Web of Science ®Google Scholar
• Matsuyama, T., A. Grossman, and H.-W. Mittruecker 1995. Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE). Nucleic Acids Res. 23: 2127–2136.
   PubMed Web of Science ®Google Scholar
• Meraz, M. A., J. M. White, K. C. F. Sheehan, E. A. Bach, S. J. Rodig, A. S. Dighe, D. H. Kaplan, J. K. Riley, A. C. Greenlund, D. Campbell, K. Carver-Moore, R. N. DuBois, R. Clark, M. Aguet, and R. D. Schreiber 1996. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84: 431–442.
   PubMed Web of Science ®Google Scholar
• Mirkovitch, J., T. Decker, Darnell J. E., Jr. 1992. Interferon induction of gene transcription analyzed by in vivo footprinting. Mol. Cell. Biol. 12: 1–9.
   PubMed Web of Science ®Google Scholar
• Miyamoto, M., T. Fujita, Y. Kimura, M. Maruyama, H. Harada, Y. Sudo, T. Miyata, and T. Taniguchi 1988. Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements. Cell 54: 903–913.
   PubMed Web of Science ®Google Scholar
• Mocarski, E. S. 1996. Cytomegaloviruses and their replication Virology. In: Fields, B. N., D. M. Knipe, and P. M. Howley2447–2492Raven Publishers, Philadelphia, Pa.
   Google Scholar
• Muller, M., J. Briscoe, C. Laxton, D. Guschin, A. Ziemiecki, O. Silvennoinen, A. G. Harpur, G. Barbieri, B. A. Withuhn, C. Schindler, S. Pellegrini, A. F. Wilks, J. N. Ihle, G. R. Stark, and I. M. Kerr 1993. The protein tyrosine kinase JAK1 complements defects in the interferon-α/β and -γ signal transduction. Nature 366: 129–135.
   PubMed Web of Science ®Google Scholar
• Muller, U., U. Steinhoff, L. F. Reis, S. Hemmi, J. Pavlovic, R. M. Zinkernagel, and M. Aguet 1994. Functional role of type I and type II interferons in antiviral defense. Science 264: 1918–1921.
   PubMed Web of Science ®Google Scholar
• Nelson, N., M. S. Marks, P. H. Driggers, and K. Ozato 1993. Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription. Mol. Cell. Biol. 13: 588–599.
   PubMed Web of Science ®Google Scholar
• Pine, R., Darnell, J. E.Jr. 1989. In vivo evidence of interaction between interferon-stimulated gene factors and the interferon-stimulated response element. Mol. Cell. Biol. 9: 3533–3537.
   PubMedGoogle Scholar
• Porter, A. C., Y. Chernajovsky, T. C. Dale, C. S. Gilbert, G. R. Stark, and I. M. Kerr 1988. Interferon response element of the human 6-16 gene. EMBO J. 7: 85–92.
   PubMed Web of Science ®Google Scholar
• Puri, P. L., M. L. Avantaggiati, C. Balsano, N. Sang, A. Graessmann, A. Giordano, and M. Levrero 1997. p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription. EMBO J. 16: 369–383.
   PubMed Web of Science ®Google Scholar
• Qureshi, S. A., M. Salditt-Georgieff, Darnell J. E., Jr. 1995. Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated gene factor 3. Proc. Natl. Acad. Sci. USA 92: 3829–3833.
   PubMedGoogle Scholar
• Reich, N., R. Pine, D. Levy, and J. E. Darnell 1987. Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A gene products. J. Virol. 62: 114–119.
   Google Scholar
• Schindler, C., X.-Y. Fu, T. Improta, R. Aebersold, Darnell J. E., Jr. 1992. Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon α. Proc. Natl. Acad. Sci. USA 89: 7836–7839.
   PubMed Web of Science ®Google Scholar
• Staeheli, P., P. Danielson, O. Haller, and J. G. Sutcliffe 1986. Transcriptional activation of the mouse Mx gene by type I interferon. Mol. Cell. Biol. 6: 4770–4774.
   PubMedGoogle Scholar
• Tevethia, M. J., and D. J. Spector 1984. Complementation of an adenovirus 5 immediate early mutant by human cytomegalovirus. Virology 137: 428–431.
   PubMedGoogle Scholar
• Thanos, D., and T. Maniatis 1992. The high mobility group protein HMG 1(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene. Cell 71: 777–789.
   PubMed Web of Science ®Google Scholar
• Tomita, Y., K. Cantell, and T. Kuwata 1982. Effects of human γ interferon on cell growth, replication of virus and induction of 2′-5′ oligoadenylate synthetase in three human lymphoblastoid cell lines and K562 cells. Int. J. Cancer 30: 161–165.
   PubMedGoogle Scholar
• Veals, S. A., T. Santa Maria, and D. E. Levy 1993. Two domains of ISGF3γ that mediate protein-DNA and protein-protein interactions during transcription factor assembly contribute to DNA-binding specificity. Mol. Cell. Biol. 13: 196–206.
   PubMed Web of Science ®Google Scholar
• Velazquez, L., M. Fellous, G. R. Stark, and S. Pellegrini 1992. A protein tyrosine kinase in the interferon α/β signaling pathway. Cell 70: 313–322.
   PubMed Web of Science ®Google Scholar
• Wen, Z., Z. Zhong, Darnell J. E., Jr. 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82: 241–250.
   PubMed Web of Science ®Google Scholar
• Yamagata, T., J. Nishida, T. Tanaka, R. Sakai, Y. Mitani, M. Yoshida, T. Taniguchi, Y. Yazaki, and H. Hirai 1996. A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes. Mol. Cell. Biol. 16: 1283–1294.
   PubMed Web of Science ®Google Scholar
• Yu-Lee, L., J. A. Hrachovy, A. M. Stevens, and L. A. Schwarz 1990. Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 T Cells. Mol. Cell. Biol. 10: 3087–3094.
   PubMed Web of Science ®Google Scholar
• Zhang, J. J., U. Vinkemeier, W. Gu, D. Chakravarti, K. Horvath, and J. Darnell 1996. Two contact regions between Stat1 and CBP/p300 in interferon γ signaling. Proc. Natl. Acad. Sci. USA 93: 15092–15096.
   PubMed Web of Science ®Google Scholar