13
Views
64
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Requirement for a Functional Interaction between Mediator Components Med6 and Srb4 in RNA Polymerase II Transcription

&
Pages 5364-5370 | Received 03 Apr 1998, Accepted 09 Jun 1998, Published online: 28 Mar 2023

REFERENCES

  • Björklund, S., and Y.-J. Kim 1996. Mediator of transcriptional regulation. Trends. Biochem. Sci. 21: 335–337.
  • Fassler, J. S., and F. Winston 1989. The Saccharomyces cderevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription. Mol. Cell. Biol. 9: 5602–5609.
  • Gadbois, E. L., D. M. Chao, J. C. Reese, M. R. Green, and R. A. Young 1997. Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo. Proc. Natl. Acad. Sci. USA 94: 3145–3150.
  • Gustafsson, C. M., L. C. Myers, Y. Li, M. J. Redd, M. Lui, H. Erdjument-Bromage, P. Tempst, and R. D. Kornberg 1997. Identification of Rox3 as a component of mediator and RNA polymerase II holoenzyme. J. Biol. Chem. 272: 48–50.
  • Hengartner, C. J., C. M. Thompson, J. Zhang, D. M. Chao, S. M. Liao, A. J. Koleske, S. Okamura, and R. A. Young 1995. Association of an activator with an RNA polymerase II holoenzyme. Genes Dev. 9: 897–910.
  • Jiang, Y. W., P. R. Dohrmann, and D. J. Stillman 1995. Genetic and physical interactions between yeast RGR1 and SIN4 in chromatin organization and transcriptional regulation. Genetics 140: 47–54.
  • Jiang, Y. W., and D. J. Stillman 1992. Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisiae. Mol. Cell. Biol. 12: 4503–4514.
  • Jiang, Y. W., and D. J. Stillman 1995. Regulation of HIS4 expression by the Saccharomyces cerevisiae SIN4 transcriptional regulator. Genetics 140: 103–114.
  • Kim, Y.-J., S. Björklund, Y. Li, M. H. Sayre, and R. D. Kornberg 1994. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77: 599–608.
  • Kohalmi, S. E., and B. A. Kunz 1988. Role of neighboring bases and assessment of strand specificity in ethylmethanesulphonate and N-methyl-N′-nitro-N-nitrosoguanidine mutagenesis in the SUP4-o gene of Saccharomyces cerevisiae. J. Mol. Biol. 204: 561–568.
  • Koleske, A. J., S. Buratowski, M. Nonet, and R. A. Young 1992. A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID. Cell 69: 883–894.
  • Koleske, A. J., and R. A. Young 1994. An RNA polymerase II holoenzyme responsive to activators. Nature 368: 466–469.
  • Kuchin, S., P. Yeghiayan, and M. Carlson 1995. Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast. Proc. Natl. Acad. Sci. USA 92: 4006–4010.
  • Lee, Y. C., S. J. Han, and Y.-J. Kim. Unpublished data.
  • Lee, Y. C., J. H. Kim, and Y.-J. Kim. Unpublished data.
  • Lee, Y. C., S. Min, B. S. Gim, and Y. J. Kim 1997. A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans. Mol. Cell. Biol. 17: 4622–4632.
  • Li, Y., S. Björklund, Y. W. Jiang, Y.-J. Kim, W. S. Lane, D. J. Stillman, and R. D. Kornberg 1995. Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc. Natl. Acad. Sci. USA 92: 10864–10868.
  • Li, Y., S. Björklund, Y. J. Kim, and R. D. Kornberg 1996. Yeast RNA polymerase II holoenzyme. Methods Enzymol. 273: 172–175.
  • Liao, S. M., J. Zhang, D. A. Jeffery, A. J. Koleske, C. M. Thompson, D. M. Chao, M. Viljoen, H. J. van Vuuren, and R. A. Young 1995. A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature 374: 193–196.
  • Muhlrad, D., R. Hunter, and R. Parker 1992. A rapid method for localized mutagenesis of yeast genes. Yeast 8: 79–82.
  • Myers, L. C., C. M. Gustafsson, D. A. Bushnell, M. Lui, H. Erdjument-Bromage, P. Tempst, and R. D. Kornberg 1998. The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev. 12: 45–54.
  • Nishizawa, M., Y. Suzuki, Y. Nogi, K. Matsumoto, and T. Fukasawa 1990. Yeast Gal11 protein mediates the transcriptional activation signal of two different transacting factors, Gal4 and general regulatory factor I/repressor/activator site binding protein 1/translation upstream factor. Proc. Natl. Acad. Sci. USA 87: 5373–5377 (Erratum, 90:302, 1993.)
  • Nonet, M. L., and R. A. Young 1989. Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II. Genetics 123: 715–724.
  • Rose, M. D., F. Winston, and P. Hieter 1990. Methods in yeast genetics: a laboratory course manual. Cold Spring Harbor Laboratory Press, Plainview, N.Y.
  • Sakai, A., Y. Shimizu, S. Kondou, T. Chibazakura, and F. Hishinuma 1990. Structure and molecular analysis of RGR1, a gene required for glucose repression of Saccharomyces cerevisiae. Mol. Cell. Biol. 10: 4130–4138.
  • Song, W., I. Treich, N. Qian, S. Kuchin, and M. Carlson 1996. SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II. Mol. Cell. Biol. 16: 115–120.
  • Suzuki, Y., Y. Nogi, A. Abe, and T. Fukasawa 1988. Gal11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae. Mol. Cell. Biol. 8: 4991–4999 (Erratum, 12:4806, 1992.)
  • Thompson, C. M., A. J. Koleske, D. M. Chao, and R. A. Young 1993. A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73: 1361–1375.
  • Thompson, C. M., and R. A. Young 1995. General requirement for RNA polymerase II holoenzymes in vivo. Proc. Natl. Acad. Sci. USA 92: 4587–4590.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.