Core Histones and HIRIP3, a Novel Histone-Binding Protein, Directly Interact with WD Repeat Protein HIRA

REFERENCES

• Albig, W., P. Kioschis, A. Poustka, K. Meergans, and D. Doenecke 1997. Human histone gene organisation: nonregular arrangement within a large cluster. Genomics 40: 314–322.
   PubMed Web of Science ®Google Scholar
• Alevizopoulos, A., Y. Dusserre, M. Tsai-Pflugfelder, T. von der Weid, W. Wahli, and N. Mermod 1995. A proline-rich TGF-β-responsive transcriptional activator interacts with histone H3. Genes Dev. 9: 3051–3066.
   PubMedGoogle Scholar
• Bortvin, A., and F. Winston 1996. Evidence that Spt6p controls chromatin structure by a direct interaction with histones. Science 272: 1473–1476.
   PubMed Web of Science ®Google Scholar
• Bours, V., G. Franzoso, V. Azarenko, S. Park, T. Kanno, K. Brown, and U. Siebenlist 1993. The oncoprotein BCL-3 directly transactivates through kappaB motifs via association with DNA-binding p50β homodimers. Cell 72: 729–739.
   PubMed Web of Science ®Google Scholar
• Budarf, M. L., and B. S. Emanuel 1997. Progress in the autosomal segmental aneusomy syndromes (SASs): single or multi-locus disorders? Hum. Mol. Genet. 6: 1657–1665.
   PubMedGoogle Scholar
• Carlson, C., H. Sirotkin, R. Pandita, R. Goldberg, J. M. McKie, R. Wadey, S. R. Patanjali, S. M. Weissman, K. Anyane-Yeboa, D. Warburton, P. Scambler, R. J. Shprintzen, R. Kucherlapati, and B. E. Morrow 1997. Molecular definition of 22q11 deletions in 151 velo-cardio-facial syndrome patients. Am. J. Hum. Genet. 61: 620–629.
   PubMedGoogle Scholar
• Carter, K. C., D. G. Bowman, W. Carrington, K. Fogarty, J. A. McNeil, F. S. Fay, and J. B. Lawrence 1993. A three-dimensional view of precursor messenger RNA metabolism within the mammalian nucleus. Science 259: 1330–1335.
   PubMedGoogle Scholar
• Cooper, J. P., S. Y. Roth, and R. T. Simpson 1994. The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure. Genes Dev. 8: 1400–1410.
   PubMedGoogle Scholar
• Dallapiccola, B., A. Pizzuti, and G. Novelli 1996. How many breaks do we need to CATCH on 22q11? Am. J. Hum. Genet. 59: 7–11.
   PubMed Web of Science ®Google Scholar
• DeSilva, H., K. Lee, and M. A. Osley 1998. Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148: 657–667.
   PubMedGoogle Scholar
• Edmonson, D. G., M. M. Smith, and S. Y. Roth 1996. Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4. Genes Dev. 10: 1247–1259.
   PubMedGoogle Scholar
• Epstein, D. J., M. Vekemans, and P. Gros 1991. Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3. Cell 67: 767–774.
   PubMed Web of Science ®Google Scholar
• Gaillard, P.-H. L., E. M. D. Martini, P. D. Kaufman, B. Stillman, E. Moustacchi, and G. Almouzni 1996. Chromatin assembly coupled to DNA repair: A new role for chromatin assembly factor-I. Cell 86: 887–896.
   PubMed Web of Science ®Google Scholar
• Gaudet, R., A. Bohm, and P. B. Sigler 1996. Crystal structure at 2.4 A resolution of the complex of transducin βγ and its regulator, phosducin. Cell 87: 577–588.
   PubMed Web of Science ®Google Scholar
• Gottlieb, S., B. S. Emanuel, D. A. Driscoll, B. Sellinger, Z. Wang, B. Roe, and M. L. Budarf 1997. The DiGeorge syndrome minimal critical region contains a Goosecoid-like (GSCL) homeobox gene that is expressed early in human development. Am. J. Hum. Genet. 60: 1194–1201.
   PubMedGoogle Scholar
• Goulding, M. D., G. Chalepakis, U. Deutsch, J. R. Erselius, and P. Gruss 1991. Pax-3, a novel murine DNA-binding protein expressed during early neurogenesis. EMBO J. 10: 1135–1147.
   PubMed Web of Science ®Google Scholar
• Gyuris, J., E. Golemis, H. Chertkov, and R. Brent 1993. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75: 791–803.
   PubMed Web of Science ®Google Scholar
• Halford, S., R. Wadey, C. Roberts, S. C. M. Daw, J. A. Whiting, H. O’Donnell, I. Dunham, D. R. Bentley, E. A. Lindsay, A. Baldini, F. Francis, H. Lehrach, R. Williamson, D. I. Wilson, J. Goodship, I. Cross, J. Burn, and P. J. Scambler 1993. Isolation of a putative transcriptional regulator from the region of 22q11 deleted in DiGeorge syndrome, Shprintzen syndrome and familial congenital heart disease. Hum. Mol. Genet. 2: 2099–2107.
   PubMed Web of Science ®Google Scholar
• Hartzog, G. A., T. Wada, H. Handa, and F. Winston 1998. Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes Dev. 12: 357–369.
   PubMed Web of Science ®Google Scholar
• Heisterkamp, N., M. P. Mulder, A. Langeveld, J. ten Hoeve, Z. Wang, B. A. Roe, and J. Groffen 1995. Localization of the human mitochondrial citrate transporter protein gene to chromosome 22q11 in the DiGeorge syndrome critical region. Genomics 29: 451–456.
   PubMedGoogle Scholar
• Holmes, S. E., M. A. Riazi, W. Gong, H. E. McDermid, B. T. Sellinger, A. Hua, F. Chen, Z. Wang, G. Zhang, B. Roe, I. Gonzalez, D. M. McDonald-McGinn, E. Zackai, B. S. Emanuel, and M. L. Budarf 1997. Disruption of the clathrin heavy chain-like gene (CLTCL) associated with features of DGS/VCFS: a balanced (21;22)(p12;q11) translocation. Hum. Mol. Genet. 6: 357–367.
   PubMedGoogle Scholar
• Kaufman, P. D., R. Kobayashi, N. Kessler, and B. Stillman 1995. The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. Cell 81: 1105–1114.
   PubMedGoogle Scholar
• Keleher, C. A., M. J. Redd, J. Schultz, M. Carlson, and A. D. Johnson 1992. Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68: 709–719.
   PubMed Web of Science ®Google Scholar
• Komachi, K., and A. D. Johnson 1997. Residues in the WD repeats of Tup1 required for interaction with α2. Mol. Cell. Biol. 17: 6023–6028.
   PubMedGoogle Scholar
• Komachi, K., M. J. Redd, and A. D. Johnson 1994. The WD repeats of Tup1 interact with the homeo domain protein α2. Genes Dev. 8: 2857–2867.
   PubMedGoogle Scholar
• Lammer, E. J., and J. M. Opitz 1986. The DiGeorge anomaly as a developmental field defect. Am. J. Med. Genet. Suppl. 2: 113–127.
   PubMedGoogle Scholar
• Lamour, V., Y. Lécluse, C. Desmaze, M. Spector, M. Bodescot, A. Aurias, M. A. Osley, and M. Lipinski 1995. A human homolog of the S. cerevisiae HIRI and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical region. Hum. Mol. Genet. 4: 791–799.
   PubMed Web of Science ®Google Scholar
• Lévy, A., S. Demczuk, A. Aurias, D. Depétris, M.-G. Mattei, and N. Philip 1995. Interstitial 22q11 microdeletions excluding the ADU breakpoint in a patient with DiGeorge syndrome. Hum. Mol. Genet. 4: 2417–2419.
   PubMedGoogle Scholar
• Llevadot, R., X. Estivill, P. Scambler, and M. Pritchard. Isolation and genomic characterization of the TUPLE1/HIRA gene of the pufferfish Fugu rubripes. Gene, in press.
   Google Scholar
• Lorain, S., S. Demczuk, V. Lamour, S. Toth, A. Aurias, B. A. Roe, and M. Lipinski 1996. Structural organization of the WD repeat protein-encoding gene HIRA in the DiGeorge syndrome critical region of human chromosome 22. Genome Res. 6: 43–50.
   PubMedGoogle Scholar
• Lüger, K., A. W. Mäder, R. K. Richmond, D. F. Sargent, and T. J. Richmond 1997. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389: 251–260.
   PubMed Web of Science ®Google Scholar
• Magnaghi, P., et al. Submitted for publication.
   Google Scholar
• Mariette, X., J.-C. Brouet, F. Danon, A. Tsapis, and K. Lassoued 1993. Nucleotide sequence analysis of the VL and VH domains of the five human IgM directed to lamin B. Evidence for an antigen-driven process in the generation of human autoantibodies to lamin B. Arthritis Rheum. 36: 1315–1324.
   PubMedGoogle Scholar
• Neer, E. J., C. J. Schmidt, R. Nambudripad, and T. F. Smith 1994. The ancient regulatory-protein family of WD-repeat proteins. Nature 371: 297–300.
   PubMed Web of Science ®Google Scholar
• Osley, M. A., and D. Lycan 1987. trans-acting regulatory mutations that alter transcription of Saccharomyces cerevisiae histone genes. Mol. Cell. Biol. 7: 4204–4210.
   PubMed Web of Science ®Google Scholar
• Read, A. P., and V. E. Newton 1997. Waardenburg syndrome. J. Med. Genet. 34: 656–665.
   PubMed Web of Science ®Google Scholar
• Redd, M. J., M. B. Arnaud, and A. D. Johnson 1997. A complex composed of Tup1 and Ssn6 represses transcription in vitro. Mol. Cell. Biol. 17: 11193–11197.
   Google Scholar
• Roberts, C., S. Daw, S. Halford, and P. J. Scambler 1997. Cloning and developmental expression analysis of chick Hira (Chira), a candidate gene for DiGeorge syndrome. Hum. Mol. Genet. 6: 237–246.
   PubMed Web of Science ®Google Scholar
• Ryan, A. K., J. A. Goodship, D. I. Wilson, N. Philip, A. Lévy, H. Seidel, S. Schuffenhauer, H. Oechsler, B. Belohradsky, M. Prieur, A. Aurias, F. L. Raymond, J. Clayton-Smith, E. Hatchwell, C. McKeon, F. A. Beemer, G. Novelli, J. A. Hurst, J. Ignatius, A. J. Green, R. M. Winter, L. Brueton, K. Brøndum-Nielsen, F. Stewart, T. Van Essen, M. Patton, H. Paterson, and P. J. Scambler 1997. Spectrum of clinical features associated with interstitial chromosome 22q11 deletions: a European collaborative study. J. Med. Genet. 34: 798–804.
   PubMed Web of Science ®Google Scholar
• Scamps, C., S. Lorain, V. Lamour, and M. Lipinski 1996. The HIR protein family: isolation and characterization of a complete murine cDNA. Biochim. Biophys. Acta 1306: 5–8.
   PubMedGoogle Scholar
• Sherwood, P. W., S. V. Tsang, and M. A. Osley 1993. Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 13: 28–38.
   PubMedGoogle Scholar
• Sirotkin, H., B. Morrow, B. Saint-Jore, A. Puech, R. Das Gupta, S. R. Patanjali, A. I. Skoultchi, S. M. Weissman, and R. Kucherlapati 1997. Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. Genomics 42: 245–251.
   PubMedGoogle Scholar
• Sondek, J., A. Bohm, D. G. Lambright, H. E. Hamm, and P. B. Sigler 1996. Crystal structure of a GA protein βγ dimer at 2.1 A resolution. Nature 379: 369–374.
   PubMed Web of Science ®Google Scholar
• Spector, M. S., A. Raff, H. DeSilva, K. Lee, and M. A. Osley 1997. Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol. Cell. Biol. 17: 545–552.
   PubMedGoogle Scholar
• Swanson, M. S., and F. Winston 1992. SPT4, SPT5 and SPT6 interactions: effects on transcription and viability in Saccharomyces cerevisiae. Genetics 132: 325–336.
   PubMed Web of Science ®Google Scholar
• Tzamarias, D., and K. Struhl 1994. Functional dissection of the yeast Cyc8-Tup1 transcriptional corepressor complex. Nature 369: 758–761.
   PubMedGoogle Scholar
• Varanasi, U., M. Klis, P. B. Mikesell, and R. J. Trumbly 1996. The Cyc8 (Ssn6)-Tup1 corepressor complex is composed of one Cyc8 and four Tup1 subunits. Mol. Cell. Biol. 16: 6707–6714.
   PubMedGoogle Scholar
• Verreault, A., P. D. Kaufman, R. Kobayashi, and B. Stillman 1996. Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. Cell 87: 95–104.
   PubMed Web of Science ®Google Scholar
• Verreault, A., P. D. Kaufman, R. Kobayashi, and B. Stillman 1997. Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase. Curr. Biol. 8: 96–108.
   Google Scholar
• Wada, T., T. Takagi, Y. Yamaguchi, A. Ferdous, T. Imai, S. Hirose, S. Sugimoto, K. Yano, G. A. Hartzog, F. Winston, S. Buratowski, and H. Handa 1998. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. Genes Dev. 12: 343–356.
   PubMed Web of Science ®Google Scholar
• Wall, M. A., D. E. Coleman, E. Lee, J. A. Iniguez-Lluhi, B. A. Posner, A. G. Gilman, and S. R. Sprang 1995. The structure of the G protein heterotrimer Giα1β12. Cell 83: 1047–1058.
   PubMed Web of Science ®Google Scholar
• Williams, F. E., and R. J. Trumbly 1990. Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae. Mol. Cell. Biol. 10: 6500–6511.
   PubMed Web of Science ®Google Scholar
• Williams, F. E., U. Varanasi, and R. J. Trumbly 1991. The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex. Mol. Cell. Biol. 11: 3307–3316.
   PubMed Web of Science ®Google Scholar
• Wilming, L. G., C. A. S. Snoeren, A. Van Rijswijk, F. Grosveld, and C. Meijers 1997. The murine homologue of HIRA, a DiGeorge syndrome candidate gene, is expressed in embryonic structures affected in human CATCH22 patients. Hum. Mol. Genet. 6: 247–259.
   PubMed Web of Science ®Google Scholar