The B29 (Immunoglobulin β-Chain) Gene Is a Genetic Target for Early B-Cell Factor

REFERENCES

• Åkerblad, P., M. Sigvardsson, and J. Leanderson 1996. Early B cell factor (EBF) down regulates immunoglobulin heavy chain intron enhancer function in a plasmacytoma cell line. Scand. J. Immunol. 44:145–149.
   Google Scholar
• Åkerblad, P. Unpublished data.
   Google Scholar
• Bain, G., E. Robanus Maandag, D. Izon, D. Amsen, A. Kruisbeek, B. Weintraub, I. Krop, M. Schlissel, A. Feeney, M. van Roon, M. van der Valk, H. te Riele, A. Berns, and J. Murre 1994. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell 79:885–892.
   PubMed Web of Science ®Google Scholar
• Borst, J., H. Jacobs, and J. Brouns 1996. Composition and function of T cell receptor and B cell receptor complexes on precursor lymphocytes. Curr. Opin. Immunol. 8:181–190.
   PubMedGoogle Scholar
• Clevers, H., and J. Grosschedl 1996. Transcriptional control of lymphoid development: lessons from gene targeting. Immunol. Today 17:336–343.
   PubMedGoogle Scholar
• Fitzsimmons, D., W. Hodsdon, W. Wheat, S.-M. Maira, B. Wasylyk, and J. Hagman 1996. Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter. Genes Dev. 10:2198–2211.
   PubMedGoogle Scholar
• Georgopoulos, K. 1997. Transcription factors required for lymphoid lineage commitment. Curr. Opin. Immunol. 9:222–227.
   PubMed Web of Science ®Google Scholar
• Gong, S., and J. Nussenzweig 1996. Regulation of an early developmental checkpoint in the B cell pathway by Igβ. Science 272:411–414.
   PubMed Web of Science ®Google Scholar
• Hagman, J., C. Belanger, A. Travis, C. Turck, and J. Grosschedl 1993. Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression. Genes Dev. 7:760–773.
   PubMedGoogle Scholar
• Hagman, J., M. Gutch, H. Lin, and J. Grosschedl 1995. EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains. EMBO J. 14:2907–2916.
   PubMedGoogle Scholar
• Hagman, J., A. Travis, and J. Grosschedl 1991. A novel lineage-specific nuclear factor regulates mb-1 gene transcription at the early stages of B cell differentiation. EMBO J. 10:3409–3417.
   PubMedGoogle Scholar
• Hardy, R., C. Carmack, S. Shinton, J. Kemp, and J. Hayakawa 1991. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173:1213–1225.
   PubMed Web of Science ®Google Scholar
• Hermanson, G., D. Eisenberg, P. Kincade, and J. Wall 1988. B29 a member of the immunoglobulin gene superfamily exclusively expressed on beta lineage cells. Proc. Natl. Acad. Sci. USA 85:6890–6894.
   PubMed Web of Science ®Google Scholar
• Hermanson, G., M. Briskin, D. Sigman, and J. Wall 1989. Immunoglobulin enhancer and promoter motifs 5′ of the B29 B-cell specific gene. Proc. Natl. Acad. Sci. USA 86:7341–7345.
   PubMedGoogle Scholar
• Hombach, J., F. Lottspeich, and J. Reth 1990. Identification of the genes encoding the Ig-α and Ig-β components of the IgM antigen receptor complex by aminoterminal sequencing. Eur. J. Immunol. 20:2795–2799.
   PubMedGoogle Scholar
• Hombach, J., T. Tsubata, L. Leclercq, H. Stappert, and J. Reth 1990. Molecular components of the B-cell antigen receptor complex of the IgM class. Nature 343:760–762.
   PubMed Web of Science ®Google Scholar
• Kadesch, T. 1992. Helix-loop-helix proteins in the regulation of immunoglobulin gene transcription. Immunol. Today 13:31–36.
   PubMedGoogle Scholar
• Kitamura, D., A. Kudo, S. Schaal, W. Muller, F. Melchers, and J. Rajewsky 1992. A critical role of λ5 protein in B cell development. Cell 69:823–831.
   PubMed Web of Science ®Google Scholar
• Li, Y.-S., R. Wasserman, K. Hayakawa, and J. Hardy 1996. Identification of the earliest B lineage stage in mouse bone marrow. Immunity 5:527–535.
   PubMed Web of Science ®Google Scholar
• Liberg, D., M. Sigvardsson, M. Bemark, and J. Leanderson 1998. Differentiation specific, octamer dependent costimulation of κ transcription. J. Immunol. 160:3899–3907.
   PubMedGoogle Scholar
• Lin, H., and J. Grosschedl 1995. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature 376:263–267.
   PubMedGoogle Scholar
• Malone, C., S. Omori, and J. Wall 1997. Silencer elements controlling the B29 (Igβ) promoter are neither promoter nor cell-type-specific. Proc. Natl. Acad. Sci. USA 94:12314–12319.
   PubMedGoogle Scholar
• Mårtensson, A., and J. Mårtensson 1997. Early B cell factor binds to a site critical for lambda5 core enhancer activity. Eur. J. Immunol. 27:315–320.
   PubMedGoogle Scholar
• Melchers, F., H. Karasuyama, D. Haasner, S. Bauer, A. Kudo, N. Sakaguchi, B. Jameson, and J. Rolink 1993. The surrogate light chain in B-cell development. Immunol. Today 14:60–68.
   PubMedGoogle Scholar
• Molkentin, J., B. Black, J. Martin, and J. Olson 1995. Cooperative activation of muscle gene expression by MEF" and myogenic bHLH proteins. Cell 83:1125–1136.
   PubMedGoogle Scholar
• Murre, C., G. Bain, M. van Dijk, I. Engel, B. Furnari, M. Massari, J. Matthews, M. Quong, R. Rivera, and J. Stuiver 1994. Structure and function of helix-loop-helix proteins. Biochim. Biophys. Acta 1218:129–135.
   PubMed Web of Science ®Google Scholar
• Omori, S., and J. Wall 1993. Multiple motifs regulate the B cell specific promoter of the B29 gene. Proc. Natl. Acad. Sci. USA 90:11732–11727.
   Google Scholar
• Persson, C., A. Måartensson, and J. Måartensson 1998. Identification of a tissue and differentiation stage specific enhancer of the VpreB1 gene. Eur. J. Immunol. 28:787–798.
   PubMedGoogle Scholar
• Schreiber, E., P. Matthias, M. Muller, and J. Schaffner 1989. Rapid detection of octamer binding proteins with “mini-extracts” prepared from a small number of cells. Nucleic Acids Res. 17:6419.
   PubMed Web of Science ®Google Scholar
• Sigvardsson, M., R. Grosschedl 1998. Transcriptional control of B cell differentiation by EBF and E47. Molecular biology of B and T cell development. In J. G. Monroe, E. V. Rothenberg (ed.), Humana Press Inc., Totowa, N.J.
   Google Scholar
• Sigvardsson, M., M. Oriordan, and J. Grosschedl 1997. EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes. Immunity 7:25–36.
   PubMed Web of Science ®Google Scholar
• Sigvardsson, M., P. Åkerblad, and J. Leanderson 1996. Early B cell factor interacts with a subset of κ promoters. J. Immunol. 156:3788–3796.
   PubMedGoogle Scholar
• Sigvardsson, M. Unpublished observation.
   Google Scholar
• Thompson, A., W. Wood, M. Gilly, M. Damore, S. Omori, and J. Wall 1996. The promoter and 5′ flanking sequences controlling human B29 gene expression. Blood 87:666–673.
   PubMedGoogle Scholar
• Tontonoz, P., E. Hu, and J. Spiegelman 1994. Stimulation of adipogenesis in fibroblasts by PPARg2, a lipid-activated transcription factor. Cell 79:1147–1156.
   PubMed Web of Science ®Google Scholar
• Travis, A., J. Hagman, and J. Grosschedl 1991. Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences. Mol. Cell. Biol. 11:5756–5766.
   PubMed Web of Science ®Google Scholar
• Travis, A., J. Hagman, L. Hwang, and J. Grosschedl 1993. Purification of early-B-cell factor and characterization of its DNA-binding specificity. Mol. Cell. Biol. 13:3392–3400.
   PubMedGoogle Scholar
• Wang, M., and J. Reed 1993. Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast. Nature 364:121–126.
   PubMed Web of Science ®Google Scholar
• Weintraub, H., R. Davis, S. Tapscott, M. Thayer, M. Krause, R. Benezra, T. Blackwell, D. Turner, R. Rupp, S. Hollenberg, Y. Zhuang, and A. Lassar. 1991. The myoD gene family: nodal point during specification of the muscle cell lineage. 251:761–766.
   Google Scholar
• Wright, W. 1992. Muscle basic helix-loop-helix proteins and the regulation of myogenesis. Curr. Opin. Genet. Dev. 2:243–248.
   PubMedGoogle Scholar
• Zhuang, Y., P. Soriano, and J. Weintraub 1994. The helix-loop-helix gene E2A is required for B cell formation. Cell 79:875–884.
   PubMedGoogle Scholar