REFERENCES
- Behrens, S. E., K. Tyc, B. Kastner, J. Reichelt, and J. Luhrmann 1993. Small nuclear ribonucleoprotein (RNP) U2 contains numerous additional proteins and has a bipartite RNP structure under splicing conditions. Mol. Cell. Biol. 13:307–319.
- Bennett, M., S. Michaud, J. Kingston, and J. Reed 1992. Protein components specifically associated with prespliceosome and spliceosome complexes. Genes Dev. 6:1986–2000.
- Bennett, M., and J. Reed 1993. Correspondence between a mammalian spliceosome component and an essential yeast splicing factor. Science 262:105–108.
- Bochnig, P., R. Reuter, P. Bringmann, and J. Luhrmann 1987. A monoclonal antibody against 2,2,7-trimethylguanosine that reacts with intact, class U, small nuclear ribonucleoproteins as well as with 7-methylguanosine-capped RNAs. Eur. J. Biochem. 168:461–467.
- Brosi, R., K. Groning, S. E. Behrens, R. Luhrmann, and J. Kramer 1993. Interaction of mammalian splicing factor SF3a with U2 snRNP and relation of its 60-kD subunit to yeast PRP9. Science 262:102–105.
- Brosi, R., H. P. Hauri, and J. Kramer 1993. Separation of splicing factor SF3 into two components and purification of SF3a activity. J. Biol. Chem. 268:17640–17646.
- Champion-Arnaud, P., and J. Reed 1994. The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site. Genes Dev. 8:1974–1983.
- Chen, E. J., A. R. Frand, E. Chitouras, and J. Kaiser 1998. A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1. Mol. Cell. Biol. 18:7139–7146.
- Chiara, M. D., and J. Reed 1995. A two-step mechanism for 5′ and 3′ splice-site pairing. Nature 375:510–513.
- Das, R., and R. Reed. Unpublished data.
- Fromont-Racine, M., J. C. Rain, and J. Legrain 1997. Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens. Nat. Genet. 16:277–282.
- Gozani, O., J. Potashkin, and J. Reed 1998. A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site. Mol. Cell. Biol. 18:4752–4760.
- Gozani, O., R. Feld, and J. Reed 1996. Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A. Genes Dev. 10:233–243.
- Habets, W. J., M. H. Hoet, B. A. De Jong, A. Van der Kemp, and J. Van Venrooij 1989. Mapping of B cell epitopes on small nuclear ribonucleoproteins that react with human autoantibodies as well as with experimentally-induced mouse monoclonal antibodies. J. Immunol. 143:2560–2566.
- Hodges, P. E., and J. Beggs 1994. RNA splicing. U2 fulfils a commitment. Curr. Biol. 4:264–267.
- Igel, H., S. Wells, R. Perriman, M. Ares Jr.. 1998. Conservation of structure and subunit interactions in yeast homologues of splicing factor 3b (SF3b) subunits. RNA 4:1–10.
- Kazantsev, A., D. Mu, A. F. Nichols, X. Zhao, S. Linn, and J. Sancar 1996. Functional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro system. Proc. Natl. Acad. Sci. USA 93:5014–5018.
- Keeney, S., G. J. Chang, and J. Linn 1993. Characterization of a human DNA damage binding protein implicated in xeroderma pigmentosum E. J. Biol. Chem. 268:21293–21300.
- Kozak, M. 1986. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44:283–292.
- Kramer, A. 1996. The structure and function of proteins involved in mammalian pre-mRNA splicing. Annu. Rev. Biochem. 65:367–409.
- Reed, R. 1996. Initial splice-site recognition and pairing during pre-mRNA splicing. Curr. Opin. Genet. Dev. 6:215–220.
- Reed, R. 1990. Protein composition of mammalian spliceosomes assembled in vitro. Proc. Natl. Acad. Sci. USA 87:8031–8035.
- Rothstein, R. 1991. Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194:281–230.
- Seghezzi, W., K. Chua, F. Shanahan, O. Gozani, R. Reed, and J. Lees 1998. Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells. Mol. Cell. Biol. 18:4526–4536.
- Staley, J. P., and J. Guthrie 1998. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92:315–326.
- Tarn, W. Y., and J. Steitz 1997. Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge. Trends Biochem. Sci. 22:132–137.
- Wang, C., K. Chua, W. Seghezzi, E. Lees, O. Gozani, and J. Reed 1998. Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis. Genes Dev. 12:1409–1414.
- Wells, S. E., M. Neville, M. Haynes, J. Wang, H. Igel, M. Ares Jr.. 1996. CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145. Genes Dev. 10:220–232.
- Will, C., C. Schneider, R. Reed, and J. Luhrmann 1999. Identification of both shared and distinct proteins in the major and minor spliceosomes. Science 284:2003–2005.
- Will, C. L., and J. Luhrmann 1997. Protein functions in pre-mRNA splicing. Curr. Opin. Cell Biol. 9:320–328.
- Yan, D., M. Ares Jr.. 1996. Invariant U2 RNA sequences bordering the branchpoint recognition region are essential for interaction with yeast SF3a and SF3b subunits. Mol. Cell. Biol. 16:818–828.
- Zhou, Z., and J. Reed 1998. Human homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicing. EMBO J. 17:2095–2106.