3
Views
7
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Cytokine Receptor Common β Chain as a Potential Activator of Cytokine Withdrawal-Induced Apoptosis

, , , , &
Pages 7399-7409 | Received 08 Apr 1999, Accepted 29 Jul 1999, Published online: 28 Mar 2023

REFERENCES

  • Appel, K., M. Buttini, A. Sauter, and J. Gebicke-Haerter 1995. Cloning of rat interleukin-3 receptor β-subunit from cultured microglia and its mRNA expression in vivo. J. Neurosci. 15:5800–5809.
  • Ashihara, E., A. M. Vannucchi, G. Migliaccio, and J. Migliaccio 1997. Growth factor receptor expression during in vitro differentiation of partially purified populations containing murine stem cells. J. Cell. Physiol. 171:343–356.
  • Bredesen, D., X. Ye, A. Tasinato, S. Sperandio, J. J. Wang, N. Assa-Munt, and J. Rabizadeh 1998. p75NTR and the concept of cellular dependence: seeing how the other half die. Cell Death Differ. 5:365–371.
  • Chao, J. R., J. M. Wang, S. F. Lee, H. W. Peng, Y. H. Lin, C. H. Chou, J. C. Li, H. M. Huang, C. K. Chou, M. L. Kuo, J. J. Y. Yen, and J. Yang-Yen 1998. mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response. Mol. Cell. Biol. 18:4883–4898.
  • Cleveland, J. L., M. Dean, N. Rosenberg, J. Y. Wang, and J. Rapp 1989. Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl. Mol. Cell. Biol. 9:5685–5695.
  • Cowling, G. J., and J. Dexter 1994. Apoptosis in the haemopoietic system. Philos. Trans. R. Soc. Lond. Ser. B 345:257–263.
  • Datta, S. R., H. Dudek, X. Tao, S. Masters, H. Fu, Y. Gotoh, and J. Greenberg 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91:231–241.
  • Devos, R., G. Plaetinck, J. Van-der-Heyden, S. Cornelis, J. Vandekerckhove, W. Fiers, and J. Tavernier 1991. Molecular basis of a high affinity murine interleukin-5 receptor. EMBO J. 10:2133–2137.
  • Dexter, T. M., A. D. Whetton, C. M. Heyworth 1986. The relevance of protein kinase C activation, glucose transport and ATP generation in the response of haemopoietic cells to growth factors, p. 163–169. In P. Kahn, T. Graf (ed.), Oncogenes and growth control. Springer-Verlag Press, Berlin, Germany.
  • Dignam, J., R. Lebovitz, and J. Roeder 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
  • Endo, T. A., M. Masuhara, M. Yokouchi, R. Suzuki, H. Sakamoto, K. Mitsui, A. Matsumoto, S. Tanimura, M. Ohtsubo, H. Misawa, T. Miyazaki, N. Leonor, T. Taniguchi, T. Fujita, Y. Kanajura, S. Komiya, and J. Yoshimura 1997. A new protein containing an SH2 domain that inhibits JAK kinases. Nature 387:921–924.
  • Gearing, D. P., J. A. King, N. M. Gough, and J. Nicola 1989. Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor. EMBO J. 8:3667–3676.
  • Gorman, D. M., N. Itoh, T. Kitamura, J. Schreurs, S. Yonehara, I. Yahara, K. Arai, and J. Miyajima 1990. Cloning and expression of a gene encoding an interleukin 3 receptor-like protein: identification of another member of the cytokine receptor gene family. Proc. Natl. Acad. Sci. USA 87:5459–5463.
  • Gossen, M., and J. Bujard 1992. Tight control of gene expression in mammalian cells by tetracycline responsive promoters. Proc. Natl. Acad. Sci. USA 89:5547–5551.
  • Hara, T., and J. Miyajima 1992. Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3). EMBO J. 11:1875–1884.
  • Hayashida, K., T. Kitamura, D. M. Gorman, K. Arai, T. Yokota, and J. Miyajima 1990. Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc. Natl. Acad. Sci. USA 87:9655–9659.
  • Hileman, M. R., B. S. Chapman, S. Rabizadeh, V. V. Krishnan, D. Bredesen, N. Assa-Munt, and J. Plesniak 1997. A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. FEBS Lett. 415:145–154.
  • Hummler, E., T. J. Cole, J. A. Blendy, R. Ganss, A. Aguzzi, W. Schmid, F. Beermann, and J. Schutz 1994. Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors. Proc. Natl. Acad. Sci. USA 91:5647–5651.
  • Itoh, N., S. Yonehara, J. Schreurs, D. M. Gorman, K. Maruyama, A. Ishii, I. Yahara, K. Arai, and J. Miyajima 1990. Cloning of an interleukin-3 receptor: a member of a distinct receptor gene family. Science 247:324–327.
  • Jacobson, M. D., M. Weil, and J. Raff 1997. Programmed cell death in animal development. Cell 88:347–354.
  • Kinoshita, T., M. Shirouzu, A. Kamiya, K. Hashimoto, S. Yokoyama, and J. Miyajima 1997. Raf/MAPK and rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells. Oncogene 15:619–627.
  • Kinoshita, T., T. Yokota, K. Arai, and J. Miyajima 1995. Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells. Oncogene 10:2207–2212.
  • Kinoshita, T., T. Yokota, K. Arai, and J. Miyajima 1995. Suppression of apoptosis death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO J. 14:266–275.
  • Kitamura, T., N. Sato, K. Arai, and J. Miyajima 1991. Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Cell 66:1165–1174.
  • Kitamura, T., T. Tange, T. Terasawa, S. Chiba, T. Kuwaki, K. Miyagawa, Y. F. Piao, K. Miyazono, A. Urabe, and J. Takaku 1989. Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J. Cell. Physiol. 140:323–334.
  • LeCouter, J. E., B. Kablar, W. R. Hardy, C. Ying, L. A. Megeney, L. L. May, and J. Rudnicki 1998. Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene. Mol. Cell. Biol. 18:7455–7465.
  • Matsumoto, A., M. Masuhara, K. Mitsui, M. Yokouchi, M. Ohtsubo, H. Misawa, A. Miyajima, and J. Yoshimura 1997. CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. Blood 89:3148–3154.
  • McKinstry, W. J., C. L. Li, J. E. Rasko, N. A. Nicola, G. R. Johnson, and J. Metcalf 1997. Cytokine receptor expression on hematopoietic stem and progenitor cells. Blood 89:65–71.
  • Metcalf, D. 1993. Hematopoietic regulators: redundancy or subtlety? Blood 82:3515–3523.
  • Minami, Y., Y. Nakagawa, A. Kawahara, T. Miyazaki, K. Sada, H. Yamamura, and J. Taniguchi 1995. Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway. Immunity 2:89–100.
  • Miura, O., J. L. Cleveland, and J. Ihle 1993. Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors. Mol. Cell. Biol. 13:1788–1795.
  • Morgensten, J. P., and J. Land 1990. Advanced mammalian gene transfer: high titer retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 18:3587–3596.
  • Mosmann, T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55–63.
  • Murakami, M., M. Narazaki, M. Hibi, H. Yawata, K. Yasukawa, M. Hamaguchi, T. Taga, and J. Kishimoto 1991. Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family. Proc. Natl. Acad. Sci. USA 88:11349–11353.
  • Naka, T., M. Narazaki, M. Hirata, T. Matsumoto, S. Minamoto, A. Aono, N. Nishimoto, T. Kajita, T. Taga, K. Yoshizaki, S. Akira, and J. Kishimoto 1997. Structure and function of a new STAT-induced STAT inhibitor. Nature 387:924–929.
  • Nishinakamura, R., N. Nakayama, Y. Hirabayashi, T. Inoue, D. Aud, T. McNeil, S. Azuma, S. Yoshida, Y. Toyoda, K. Arai, A. Miyajima, and J. Murray 1995. Mice deficient for the IL-3/GM-CSF/IL-5 βc receptor exhibit lung pathology and impaired immune response, while βIL-3 receptor-deficient mice are normal. Immunity 2:211–222.
  • Nishinakamura, R., A. Miyajima, P. J. Mee, V. L. J. Tybulewixz, and J. Murray 1996. Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-5 functions. Blood 88:2458–2464.
  • Ogata, N., T. Kouro, A. Yamada, M. Koike, N. Hanai, T. Ishikawa, and J. Takatsu 1998. JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor α and βc subunit, respectively, and are activated upon IL-5 stimulation. Blood 91:2264–2271.
  • Ohta, T., T. Kinoshita, M. Naito, T. Nozaki, M. Masutani, T. Tsuruo, and J. Miyajima 1997. Requirement of the caspase-3/CPP32 protease cascade for apoptotic death following cytokine deprivation in hematopoietic cells. J. Biol. Chem. 272:23111–23116.
  • O’Neal, K. D., and J. Yu-Lee 1993. The proline-rich motif (PRM): a novel feature of the cytokine/hematopoietin receptor superfamily. Lymphokine Cytotokine Res. 12:309–312.
  • Palacios, R., and J. Steinmetz 1985. IL-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo. Cell 41:727–734.
  • Pear, W. S., G. P. Nolan, M. L. Scott, and J. Baltimore 1993. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 88:8392–8396.
  • Quelle, F. W., N. Sato, B. A. Witthuhn, R. C. Inhorn, M. Eder, A. Miyajima, J. D. Griffin, and J. Ihle 1994. JAK2 associates with the βc chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol. Cell. Biol. 14:4335–4341.
  • Rabizadeh, S., J. Oh, L. T. Zhong, J. Yang, C. M. Bitler, L. L. Butcher, and J. Bredesen 1993. Induction of Apoptosis by the low-affinity NGF receptor. Science 261:345–348.
  • Rao, P., and J. Mufson 1995. A membrane proximal domain of the human interleukin-3 receptor βc subunit that signals DNA synthesis in NIH 3T3 cells specifically binds a complex of Src and Janus family tyrosine kinases and phosphatidylinositol 3-kinase. J. Biol. Chem. 270:6886–6893.
  • Sakamaki, K., I. Miyajima, T. Kitamura, and J. Miyajima 1992. Critical cytoplasmic domains of the common β subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation. EMBO J. 11:3541–3549.
  • Sato, N., K. Sakamaki, N. Terada, K. Arai, and J. Miyajima 1993. Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common β subunit responsible for different signaling. EMBO J. 12:4181–4189.
  • Sato, S., T. Katagiri, S. Takaki, Y. Kikuchi, Y. Hitoshi, S. Yonehara, S. Tsukada, D. Kitamura, T. Watanabe, O. Witte, and J. Takatsu 1994. IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton’s tyrosine and Janus 2 kinases. J. Exp. Med. 180:2101–2111.
  • Scheid, M. P., and J. Duronio 1998. Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation. Proc. Natl. Acad. Sci. USA 95:7439–7444.
  • Scott, C. L., D. A. Hughes, D. Cary, N. A. Nicola, C. G. Begley, and J. Robb 1998. Functional analysis of mature hematopoietic cells from mice lacking the βc chain of the granulocyte-macrophage colony-stimulating factor receptor. Blood 92:4119–4127.
  • Shalit, M., S. Sekhsaria, and J. Malech 1995. Modulation of growth and differentiation of eosinophils from human peripheral blood CD34+ cells by IL5 and other growth factors. Cell Immunol. 160:50–57.
  • Starr, R., T. A. Willson, E. M. Viney, L. J. L. Murray, J. R. Rayner, B. J. Jenkins, T. J. Gonda, W. S. Alexander, D. Metcalf, N. A. Nicola, and J. Hilton 1997. A family of cytokine-inducible inhibitors of signalling. Nature 387:917–921.
  • Tartaglia, L. A., T. M. Ayres, G. H. W. Wong, and J. Goeddel 1993. A novel domain within the 55 kd TNF receptor signals cell death. Cell 74:845–853.
  • Tavernier, J., R. Devos, S. Cornelis, T. Tuypens, J. Van-der-Heyden, W. Fiers, and J. Plaetinck 1991. A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF. Cell 66:1175–1184.
  • Watson, J. 1979. Continuous proliferation of murine antigen-specific helper T lymphocytes in culture. J. Exp. Med. 150:1510–1519.
  • Williams, G. T., C. A. Smith, E. Spooncer, T. M. Dexter, and J. Taylor 1990. Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature. 343:76–79.
  • Wognum, A. W., M. O. de-Jong, and J. Wagemaker 1996. Differential expression of receptors for hemopoietic growth factors on subsets of CD34+ hemopoietic cells. Leuk. Lymphoma 24:11–25.
  • Wyllie, A. H. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284:555–556.
  • Yen, J. J. Y., Y. C. Hsieh, C. L. Yen, C. C. Chang, S. Lin, and J. Yang-Yen 1995. Restoring the apoptosis suppression response to IL-5 confers on erythroleukemic cells a phenotype of IL-5-dependent growth. J. Immunol. 154:2144–2152.
  • Yoshimura, A., T. Ohkubo, T. Kigushi, N. A. Jenkins, D. J. Gilbert, N. G. Copeland, T. Hara, and J. Miyajima 1995. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J. 14:2816–2826.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.