The Saccharomyces cerevisiae Homologues of Endonuclease III from Escherichia coli, Ntg1 and Ntg2, Are Both Required for Efficient Repair of Spontaneous and Induced Oxidative DNA Damage in Yeast

REFERENCES

• Ames, B. N., L. S. Gold, and J. Willett 1995. The causes and prevention of cancer. Proc. Natl. Acad. Sci. USA 92:5258–5265.
   PubMed Web of Science ®Google Scholar
• Aspinwall, R., D. G. Rothwell, T. Roldan-Arjona, C. Anselmino, C. J. Ward, J. P. Cheadle, J. R. Sampson, T. Lindahl, P. C. Harris, and J. Hickson 1997. Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III. Proc. Natl. Acad. Sci. USA 94:109–114.
   PubMed Web of Science ®Google Scholar
• Augeri, L., L. Lee, A. B. Barton, and J. Doetsch 1997. Purification, characterization, gene cloning, and expression of Saccharomyces cerevisiae redoxyendonuclease, a homolog of Escherichia coli endonuclease III. Biochemistry 36:721–729.
   PubMed Web of Science ®Google Scholar
• Barton, A. B., and J. Kaback 1994. Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: analysis of the genes in the FUN38-MAK16-SPO7 region. J. Bacteriol. 176:1872–1880.
   PubMedGoogle Scholar
• Bjørås, M., L. Luna, B. Johnsen, E. Hoff, T. Haug, T. Rognes, and J. Seeberg 1997. Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites. EMBO J. 16:6314–6322.
   PubMed Web of Science ®Google Scholar
• Boiteux, S., and J. Huisman 1989. Isolation of a formamidopyrimidine-DNA glycosylase (fpg) mutant of Escherichia coli K12. Mol. Gen. Genet. 215:300–305.
   PubMedGoogle Scholar
• Boiteux, S., and J. Laval 1983. Imidazole open ring 7-methylguanine: an inhibitor of DNA synthesis. Biochem. Biophys. Res. Commun. 110:552–558.
   PubMed Web of Science ®Google Scholar
• Boiteux, S., T. R. O’Connor, and J. Laval 1987. Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein. EMBO J. 6:3177–3183.
   PubMed Web of Science ®Google Scholar
• Bruner, S. D., H. M. Nash, W. S. Lane, and J. Verdine 1998. Repair of oxidatively damaged guanine in Saccharomyces cerevisiae by an alternative pathway. Curr. Biol. 8:393–403.
   PubMed Web of Science ®Google Scholar
• Cadet, J., P. Vigny 1990. Photochemistry of nucleic acids, p. 1–272. In H. Morrison (ed.), Bioorganic photochemistry. John Wiley & Sons, New York, N.Y.
   Google Scholar
• Caldecott, K. W., C. K. McKeown, J. D. Tucker, S. Ljungquist, and J. Thompson 1994. An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III. Mol. Cell. Biol. 14:68–76.
   PubMed Web of Science ®Google Scholar
• Croteau, D. L., and J. Bohr 1997. Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J. Biol. Chem. 272:25409–25412.
   PubMed Web of Science ®Google Scholar
• Cunningham, R. P. 1997. DNA glycosylases. Mutat. Res. 383:189–196.
   PubMedGoogle Scholar
• Demple, B., and J. Harrison 1994. Repair of oxidative damage to DNA: enzymology and biology. Annu. Rev. Biochem. 63:915–948.
   PubMed Web of Science ®Google Scholar
• Dodson, M. L., R. D. Schrock III, and J. Lloyd 1993. Evidence for an imino intermediate in the T4 endonuclease V reaction. Biochemistry 32:8284–8290.
   PubMedGoogle Scholar
• Doetsch, P. W., T. H. Zasatawny, A. M. Martin, and J. Dizdaroglu 1995. Monomeric base damage products from adenine, guanine, and thymine induced by exposure of DNA to ultraviolet radiation. Biochemistry 34:737–742.
   PubMed Web of Science ®Google Scholar
• Eide, L., M. Bjørås, M. Pirovano, I. Alseth, K. G. Berdal, and J. Seeberg 1996. Base excision of oxidative purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence similarity to endonuclease III from Escherichia coli. Proc. Natl. Acad. Sci. USA 93:10735–10740.
   PubMed Web of Science ®Google Scholar
• Feig, D. I., L. C. Sowers, and J. Loeb 1994. Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. Proc. Natl. Acad. Sci. USA 91:6609–6613.
   PubMed Web of Science ®Google Scholar
• Girard, P. M., P. M. Guibourt, and J. Boiteux 1997. The Ogg1 protein of Saccharomyces cerevisiae: a 7,8-dihydro-8-oxoguanine DNA glycosylase/AP-lyase whose lysine 241 is a critical residue for catalytic activity. Nucleic Acids Res. 25:3204–3211.
   PubMed Web of Science ®Google Scholar
• Hatahet, Z., Y. W. Kow, A. A. Purmal, R. P. Cunningham, and J. Wallace 1994. New substrates for old enzymes. 5-Hydroxy-2′-deoxycytidine and 5-hydroxy-2′-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2′-deoxyuridine is a substrate for uracil DNA N-glycosylase. J. Biol. Chem. 269:18814–18820.
   PubMed Web of Science ®Google Scholar
• Hilbert, T. P., W. Chaung, R. J. Boorstein, R. P. Cunningham, and J. Teebor 1997. Cloning and expression of the cDNA encoding the human homologue of the DNA repair enzyme, Escherichia coli endonuclease III. J. Biol. Chem. 272:6733–6740.
   PubMed Web of Science ®Google Scholar
• Hill, J., K. A. Donald, and J. Griffiths 1991. DMSO-enhanced whole cell yeast transformation. Nucleic Acids Res. 19:5791.
   PubMed Web of Science ®Google Scholar
• Ide, H., Y. W. Kow, and J. Wallace 1985. Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro. Nucleic Acids Res. 13:8035–8052.
   PubMed Web of Science ®Google Scholar
• Kasai, H., S. Nishimura 1991. Formation of 8-hydroxydeoxyguaninosine in DNA by oxygen radicals and its biological significance, p. 99–116. In H. Sies (ed.), Oxidative stress: oxidants and antioxidants. Academic Press, London, England.
   Google Scholar
• Kasai, H., P. F. Crain, Y. Kuchino, S. Nishimura, A. Ootsuyama, and J. Tanooka 1986. Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis 7:1849–1851.
   PubMed Web of Science ®Google Scholar
• Krokan, H. E., R. Standal, and J. Slupphaug 1997. DNA glycosylases in the base excision repair of DNA. Biochem. J. 325:1–16.
   PubMed Web of Science ®Google Scholar
• Kubota, Y., R. A. Nash, A. Klungland, P. Schär, D. Barnes, and J. Lindahl 1996. Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase β and the XRCC1 protein. EMBO J. 15:6662–6670.
   PubMed Web of Science ®Google Scholar
• Kuo, C. F., D. E. McRee, C. L. Fisher, S. F. O’Handley, R. P. Cunningham, and J. Tainer 1992. Atomic structure of the DNA repair [4Fe-4S] enzyme endonuclease III. Science 258:434–440.
   PubMedGoogle Scholar
• Leadon, S. A., S. L. Barbee, and J. Dunn 1995. The yeast RAD2, but not RAD1, gene is involved in the transcription-coupled repair of thymine glycols. Mutat. Res. 337:169–178.
   PubMedGoogle Scholar
• Macreadie, I. G., M. N. Jagadish, A. A. Azad, and J. Vaughan 1989. Versatile cassettes designed for the copper inducible expression of protein in yeast. Plasmid 21:147–150.
   PubMed Web of Science ®Google Scholar
• Melamede, R. J., Z. Hatahet, Y. W. Kow, H. Ide, and J. Wallace 1994. Isolation and characterization of endonuclease VIII from Escherichia coli. Biochemistry 33:1255–1264.
   PubMed Web of Science ®Google Scholar
• Michaels, M. L., L. Pham, C. Cruz, and J. Miller 1991. MutM, a protein that prevents G.C----T.A transversions, is formamidopyrimidine-DNA glycosylase. Nucleic Acids Res. 19:3629–3632.
   PubMed Web of Science ®Google Scholar
• Nakai, K., and J. Kanehisa 1992. A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics 14:897–911.
   PubMed Web of Science ®Google Scholar
• Roldan-Arjona, T., C. Anselmino, and J. Lindahl 1996. Molecular cloning and functional analysis of a Schizosaccharomyces pombe homologue of Escherichia coli endonuclease III. Nucleic Acids Res. 24:3307–3312.
   PubMed Web of Science ®Google Scholar
• Rouet, P., and J. Essigmann 1985. Possible role for thymine glycol in the selective inhibition of DNA synthesis on oxidized DNA templates. Cancer Res. 45:6113–6118.
   PubMedGoogle Scholar
• Seeberg, E. 1978. Reconstitution of an Escherichia coli repair endonuclease activity from the separated uvrA+ and uvrB+/uvrC+ gene products. Proc. Natl. Acad. Sci. USA 75:2569–2573.
   PubMed Web of Science ®Google Scholar
• Seeberg, E., L. Eide, and J. Bjørås 1995. The base excision repair pathway. Trends Biochem. Sci. 20:391–397.
   PubMedGoogle Scholar
• Suter, B., M. Livingstone-Zatchej, and J. Thoma 1997. Chromatin structure modulates DNA repair by photolyase in vivo. EMBO J. 16:2150–2160.
   PubMed Web of Science ®Google Scholar
• Tchou, J., H. Kasai, S. Shibutani, M. H. Chung, J. Laval, A. P. Grollman, and J. Nishimura 1991. 8-Oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity. Proc. Natl. Acad. Sci. USA 88:4690–4694.
   PubMed Web of Science ®Google Scholar
• Thayer, M. M., H. Ahern, D. Xing, R. P. Cunningham, and J. Tainer 1995. Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure. EMBO J. 14:4108–4120.
   PubMedGoogle Scholar
• Wilson, R., R. Ainscough, K. Anderson, C. Baynes, M. Berks, J. Bonfield, J. Burton, M. Connell, T. Copsey, J. Cooper, A. Coulson, M. Craxton, S. Dear, Z. Du, R. Durbin, A. Favello, A. Fraser, L. Fulton, and J. Gardner 1994. 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature 368:32–38.
   PubMed Web of Science ®Google Scholar
• You, H. J., R. L. Swanson, and J. Doetsch 1998. Saccharomyces cerevisiae possesses two functional homologues of Escherichia coli endonuclease III. Biochemistry 37:6033–6040.
   PubMedGoogle Scholar