19
Views
80
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

The Naturally Occurring Mutants of DDB Are Impaired in Stimulating Nuclear Import of the p125 Subunit and E2F1-Activated Transcription

, , , , , & show all
Pages 4935-4943 | Received 25 Feb 1999, Accepted 23 Apr 1999, Published online: 28 Mar 2023

REFERENCES

  • Becker, S. A., T.-H. Lee, J. S. Butel, and J. Slagle 1998. Hepatitis B virus X protein interferes with cellular DNA repair. J. Virol. 72:266–272.
  • Bohr, V. A., D. S. Okumoto, and J. Hanawalt 1986. Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene. Proc. Natl. Acad. Sci. USA 83:3830–3833.
  • Chu, G., and J. Chang 1988. Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA. Science 242:564–567.
  • Dantonel, J.-C., K. G. K. Murthy, J. L. Manley, and J. Tora 1997. Transcription factor TFIID recruits factor CPSF for formation of 3′ end of mRNA. Nature 389:399–402.
  • de Weerd-Kastelein, E. A., W. Keijzer, and J. Bootsma 1974. A third complementation group in xeroderma pigmentosum. Mutat. Res. 22:87–91.
  • Dignam, J. D., R. M. Lebovitz, and J. Roeder 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
  • Dualan, R., T. Brody, S. Keeney, A. F. Nichols, A. Admon, and J. Linn 1995. Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein. Genomics 29:62–69.
  • Field, S. J., F. Y. Tsai, F. Kuo, A. M. Zubiaga, W. G. Kaelin Jr., D. M. Livingston, S. H. Orkin, and J. Greenberg 1996. E2F1 functions in mice to promote apoptosis and suppress proliferation. Cell 85:549–561.
  • Fornerod, M., M. Ohno, M. Yoshida, and J. Mattaj 1997. Crm1 is an export receptor for leucine-rich nuclear export signals. Cell 90:1051–1060.
  • Friedberg, E. C. 1996. Relationships between DNA repair and transcription. Annu. Rev. Biochem. 65:15–42.
  • Fukuda, M., S. Asano, T. Nakamura, M. Adachi, M. Yoshida, M. Yanagida, and J. Nishida 1997. CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature 390:308–311.
  • Harlow, E., D. Lane 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Hayes, S., P. Shiyanov, X. Chen, and J. Raychaudhuri 1998. DDB, a putative DNA repair protein, can function as a transcriptional partner of E2F1. Mol. Cell. Biol. 18:240–249.
  • Henning, K. A., L. Li, N. Iyer, L. D. McDaniel, M. S. Reagan, R. Legerski, R. A. Schultz, M. Stefanini, A. R. Lehman, L. V. Mayne, and J. Friedberg 1995. The Cockayne syndrome group A gene product encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell 82:555–564.
  • Hsiao, K. M., S. L. McMahon, and J. Farnham 1994. Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. Genes Dev. 8:1526–1537.
  • Hwang, B. J., and J. Chu 1993. Purification and characterization of a human protein that binds to damaged DNA. Biochemistry 32:1657–1666.
  • Hwang, B. J., J. C. Liao, and J. Chu 1996. Isolation of a cDNA encoding a UV-damaged DNA binding factor defective in xeroderma pigmentosum group E cells. Mutat. Res. 362:105–117.
  • Hwang, B. J., S. Toering, U. Francke, and J. Chu 1998. p48 activates a UV-damaged-DNA binding factor and is defective in xeroderma pigmentosum group E cells that lack binding activity. Mol. Cell. Biol. 18:4391–4399.
  • Johnson, D. G., K. Ohtani, and J. Nevins 1994. Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev. 8:1514–1525.
  • Kazantsev, A., D. Mu, A. F. Nichols, X. Zhao, S. Linn, and J. Sancar 1996. Functional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro system. Proc. Natl. Acad. Sci. USA 93:5014–5018.
  • Keeney, S., G. J. Chang, and J. Linn 1993. Characterization of a human DNA damage binding protein implicated in xeroderma pigmentosum E. J. Biol. Chem. 268:21293–21300.
  • Keeney, S., A. P. Eker, T. Brody, W. Vermeulen, D. Bootsma, J. H. Hoeijmakers, and J. Linn 1994. Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein. Proc. Natl. Acad. Sci. USA 91:4053–4056.
  • Kondo, S. J., S. Fukuro, A. Mamada, A. Kawada, and J. Satoh 1988. Assignment of three patients with xeroderma pigmentosum to complementation group E and their characteristics. J. Investig. Dermatol. 90:152–157.
  • Krishnamoorthy, R. R., T.-H. Lee, J. S. Butel, and J. Das 1997. Apolipoprotein B gene regulatory factor-2 (BRF-2) is structurally and immunologically highly related to hepatitis B virus S associated protein-1 (XAP-1). Biochemistry 36:960–969.
  • Kudo, N., S. Khochbin, K. Nishi, K. Kitano, M. Yanagida, M. Yoshida, and J. Horinouchi 1997. Molecular cloning and cell cycle dependent expression of mammalian CRM1, a protein involved in nuclear export. J. Biol. Chem. 272:29742–29751.
  • Lee, T. H., S. J. Elledge, and J. Butel 1995. Hepatitis B virus X protein interacts with a probable cellular DNA repair protein. J. Virol. 69:1107–1114.
  • Lin, G. Y., R. G. Paterson, C. D. Richardson, and J. Lamb 1998. The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding protein. Virology 249:189–200.
  • Nevins, J. R. 1998. Towards an understanding of the functional complexity of the E2F and retinoblastoma families. Cell Growth Differ. 9:585–593.
  • Nichols, A. F., P. Ong, and J. Linn 1996. Mutations specific to the xeroderma pigmentosum group E Ddb-phenotype. J. Biol. Chem. 271:24317–24320.
  • Otrin, V. R., I. Kuraoka, T. Nardo, M. McLenigan, A. P. M. Eker, M. Stefanini, A. S. Levine, and J. Wood 1998. Relationship of the xeroderma pigmentosum group E DNA repair defect to the chromatin and DNA binding proteins UV-DDB and replication protein A. Mol. Cell. Biol. 18:3182–3190.
  • Qin, X. Q., D. M. Livingston, W. Kaelin Jr., and J. Adams 1994. Deregulated transcription factor E2F1 expression leads to S phase entry and apoptosis. Proc. Natl. Acad. Sci. USA 91:10918–10922.
  • Reardon, J. T., A. F. Nichols, S. Keeney, C. A. Smith, J. S. Taylor, S. Linn, and J. Sancar 1993. Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli damage recognition protein (UvrA) to the major ultraviolet photoproducts: T[c,s]T, T[t,s]T, T[6-4]T, and T[Dewar]T. J. Biol. Chem. 268:21301–21308.
  • Schreiber, E., P. Matthias, M. M. Muller, and J. Schaffner 1989. Rapid detection of octamer binding proteins with mini-extracts, prepared from a small number of cells. Nucleic Acids Res. 17:6419–6420.
  • Seed, B., and J. Sheen 1988. A simple phase-extraction assay for chloramphenicol acyltransferase activity. Gene 67:271–277.
  • Shan, B., and J. Lee 1994. Deregulated expression of E2F1 induces S phase entry and apoptosis. Mol. Cell. Biol. 14:8166–8173.
  • Shiyanov, P., S. Bagchi, G. Adami, J. Kokontis, N. Hay, M. Arroyo, A. Morozov, and J. Raychaudhuri 1996. p21 disrupts the interaction between cdk2 and the E2F-p130 complex. Mol. Cell. Biol. 16:737–744.
  • Shiyanov, P., S. Hayes, N. Chen, D. G. Pestov, L. F. Lau, and J. Raychaudhuri 1997. p27Kip1 induces an accumulation of the repressor complexes of E2F and inhibits expression of the E2F-regulated genes. Mol. Biol. Cell 8:1815–1827.
  • Sitterlin, D., T.-H. Lee, S. Progent, P. Tiollais, J. S. Butel, and J. Transy 1997. Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutants. J. Virol. 71:6194–6199.
  • van Assendelft, G. B., E. M. Rigney, and J. Hickson 1993. Purification of a HeLa cell nuclear protein that binds selectively to DNA irradiated with ultra-violet light. Nucleic Acids Res. 21:3399–3404.
  • Wu, X., and J. Levine 1994. p53 and E2F1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA 91:3802–3808.
  • Yamasaki, L., T. Jacks, R. T. Bronson, E. Harlow, and J. Dyson 1996. Tumor induction and tissue atrophy in mice lacking E2F1. Cell 85:537–548.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.