Cloning and Characterization of Two Evolutionarily Conserved Subunits (TFIIIC102 and TFIIIC63) of Human TFIIIC and Their Involvement in Functional Interactions with TFIIIB and RNA Polymerase III

REFERENCES

• Arrebola, R., N. Manaud, S. Rozenfeld, M. C. Marsolier, O. Lefebvre, C. Carles, P. Thuriaux, C. Conesa, and J. Sentenac 1998. τ91, an essential subunit of yeast transcription factor IIIC, cooperates with τ138 in DNA binding. Mol. Cell. Biol. 18:1–9.
   PubMedGoogle Scholar
• Bartholomew, B., G. A. Kassavetis, B. R. Braun, and J. Geiduschek 1990. The subunit structure of Saccharomyces cerevisiae transcription factor IIIC probed with a novel photocrosslinking regent. EMBO J. 9:2197–2205.
   PubMedGoogle Scholar
• Bartholomew, B., G. A. Kassavetis, and J. Geiduschek 1991. Two components of Saccharomyces cerevisiae TFIIIB are stereospecifically located upstream of a tRNA gene and interact with the second largest subunit of TFIIIC. Mol. Cell. Biol. 11:5181–5189.
   PubMedGoogle Scholar
• Bartholomew, B., D. Durkovich, G. A. Kassavetis, and J. Geiduschek 1993. Orientation and topography of RNA polymerase III in transcription complexes. Mol. Cell. Biol. 13:942–952.
   PubMed Web of Science ®Google Scholar
• Bieker, J. J., P. L. Martin, and J. Roeder 1985. Formation of a rate-limiting intermediate in 5S RNA gene transcription. Cell 40:119–127.
   PubMed Web of Science ®Google Scholar
• Brun, I., A. Sentenac, and J. Werner 1997. Dual role of the C34 subunit of RNA polymerase III in transcription initiation. EMBO J. 16:5730–5741.
   PubMed Web of Science ®Google Scholar
• Burnol, A. F., F. Margottin, J. Huet, G. Almouzni, M. N. Prioleau, M. Mechali, and J. Sentenac 1993. TFIIIC relieves repression of U6 snRNA transcription by chromatin. Nature 362:475–477.
   PubMedGoogle Scholar
• Chaussivert, N., C. Conesa, S. Shaaban, and J. Sentenac 1995. Complex interactions between yeast TFIIIB and TFIIIC. J. Biol. Chem. 270:15353–15358.
   PubMedGoogle Scholar
• Chiannilkulchai, N., R. Stalder, M. Riva, C. Carles, M. Werner, and J. Sentenac 1992. RPC82 encodes the highly conserved, third-largest subunit of RNA polymerase C (III) from Saccharomyces cerevisiae. Mol. Cell. Biol. 12:4433–4440.
   PubMed Web of Science ®Google Scholar
• Das, A. K., P. T. W. Cohen, and J. Barford 1998. The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions. EMBO J. 17:1192–1199.
   PubMed Web of Science ®Google Scholar
• Gabrielsen, O. S., and J. Sentenac 1991. RNA polymerase III(C) and its transcription factors. Trends Biochem. Sci. 16:412–416.
   PubMed Web of Science ®Google Scholar
• Geiduschek, E. P., G. A. Kassavetis 1992. RNA polymerase III transcription complexes, p. 247–280. In K. Yamamoto (ed.), Transcription regulation. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Harlow, E., D. Lane 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Hirano, T., N. Kinoshita, K. Morikawa, and J. Yanagida 1990. Snap helix with knob and hole: essential repeats in S. pombe nuclear protein nuc2+. Cell 60:319–328.
   PubMed Web of Science ®Google Scholar
• Hsieh, Y., Z. Wang, and R. G. Roeder. Unpublished data.
   Google Scholar
• Joazeiro, C. A. P., G. A. Kassavetis, and J. Geiduschek 1996. Alternative outcomes in assembly of promoter complexes: the roles of TBP and a flexible linker in placing TFIIIB on tRNA genes. Genes Dev. 10:725–739.
   PubMedGoogle Scholar
• Kassavetis, G. A., B. R. Braun, L. H. Nguyen, and J. Geiduschek 1990. S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors. Cell 60:235–245.
   PubMed Web of Science ®Google Scholar
• Kassavetis, G. A., C. A. P. Joazeiro, M. Pisano, E. P. Geiduschek, T. Colbert, S. Hahn, and J. Blanco 1992. The role of the TATA binding protein in the assembly and function of the multisubunit yeast RNA polymerase III, transcription factor TFIIIB. Cell 71:1055–1064.
   PubMed Web of Science ®Google Scholar
• Kassavetis, G. A., C. Bardeleben, B. Bartholomew, B. R. Braun, C. A. P. Joazeiro, M. Pisano, E. P. Geiduschek 1994. Transcription by RNA polymerase III, p. 107–126. In R. C. Conaway, J. W. Conaway (ed.), Transcription: mechanisms and regulation. Raven Press, New York, N.Y.
   Google Scholar
• Kassavetis, G. A., A. Kumar, E. Ramirez, and J. Geiduschek 1998. Functional and structural organization of Brf, the TFIIB-related component of the RNA polymerase III transcription initiation complex. Mol. Cell. Biol. 18:5587–5599.
   PubMedGoogle Scholar
• Khoo, B., B. Brophy, and J. Jackson 1994. Conserved functional domains of the RNA polymerase III general transcription factor BRF. Genes Dev. 8:2879–2890.
   PubMed Web of Science ®Google Scholar
• Kovelman, R., and J. Roeder 1992. Purification and characterization of two forms of human transcription factor IIIC. J. Biol. Chem. 267:24446–24456.
   PubMedGoogle Scholar
• Kundu, T. K., Z. Wang, and J. Roeder 1999. Human TFIIIC relieves chromatin-mediated repression of RNA polymerase III transcription and contains an intrinsic histone acetyltransferase activity. Mol. Cell. Biol. 19:1605–1615.
   PubMedGoogle Scholar
• Lagna, G., R. Kovelman, J. Sukegawa, and J. Roeder 1994. Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC. Mol. Cell. Biol. 14:3053–3064.
   PubMedGoogle Scholar
• Lamb, J. R., S. Tugendreich, and J. Hieter 1995. Tetratricopeptide repeat interaction: to TPR or not to TPR? Trends Biochem. Sci. 20:257–258.
   PubMed Web of Science ®Google Scholar
• Lassar, A. B., P. L. Martin, and J. Roeder 1983. Transcription of class III genes: formation of preinitiation complexes. Science 222:740–748.
   PubMed Web of Science ®Google Scholar
• L’Etoile, M. D., M. L. Fahnestock, Y. Shen, R. Aebersold, and J. Berk 1994. Human transcription factor TFIIIC box B binding subunit. Proc. Natl. Acad. Sci. USA 91:1652–1656.
   PubMedGoogle Scholar
• Manaud, N., R. Arrebola, B. Buffin-Meyer, O. Lefebvre, H. Voss, M. Riva, C. Conesa, and J. Sentenac 1998. A chimeric subunit of yeast transcription factor IIIC forms a subcomplex with τ95. Mol. Cell. Biol. 18:3191–3200.
   PubMedGoogle Scholar
• Marck, C., O. Lefebvre, C. Carles, M. Riva, N. Chaussivert, A. Ruet, and J. Sentenac 1993. The TFIIIB-assembling subunit of yeast transcription factor TFIIIC has both tetratricopeptide repeats and basic helix-loop-helix motifs. Proc. Natl. Acad. Sci. USA 90:4027–4031.
   PubMedGoogle Scholar
• Mital, R., R. Kobayashi, and J. Hernandez 1996. RNA polymerase III transcription from the human U6 and adenovirus type 2 VAI promoters has different requirements for human BRF, a subunit of human TFIIIB. Mol. Cell. Biol. 16:7031–7042.
   PubMedGoogle Scholar
• Moir, R. A., I. Sethy-Coraci, K. Puglia, M. D. Librizzi, and J. Willis 1997. A tetratricopeptide repeat mutation in yeast transcription factor IIIC131 (TFIIIC131) facilitates recruitment of TFIIIB-related factor TFIIIB70. Mol. Cell. Biol. 17:7119–7125.
   PubMedGoogle Scholar
• Parsons, M., and J. Weil 1992. Cloning of TFC1, the Saccharomyces cerevisiae gene encoding the 95-kDa subunit of transcription factor TFIIIC. J. Biol. Chem. 267:2894–2901.
   PubMed Web of Science ®Google Scholar
• Ruth, J., C. Conesa, G. Dieci, O. Lefebvre, A. Dusterhoft, S. Ottonello, and J. Sentenac 1996. A supressor of mutations in the class III transcription system encodes a component of yeast TFIIIB. EMBO J. 15:1941–1949.
   PubMedGoogle Scholar
• Sikorski, R. S., M. S. Boguski, M. Goebl, and J. Hieter 1990. A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis. Cell 60:307–317.
   PubMedGoogle Scholar
• Sinn, E., Z. Wang, R. Kovelman, and J. Roeder 1995. Cloning and characterization of a TFIIIC2 subunit (TFIIICβ) whose presence correlates with activation of RNA polymerase III mediated transcription by adenovirus E1A expression and serum factors. Genes Dev. 9:675–685.
   PubMed Web of Science ®Google Scholar
• Studier, F. W., A. H. Rosenberg, J. J. Dunn, and J. Dubendorff 1990. Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol. 185:60–89.
   PubMed Web of Science ®Google Scholar
• Swanson, R. N., C. Conesa, O. Lefebvre, C. Carles, A. Ruet, E. Quemenur, J. Gagnon, and J. Sentenac 1991. Isolation of TFC1, a gene encoding one of two DNA-binding subunits of yeast transcription factor τ (TFIIIC). Proc. Natl. Acad. Sci. USA 88:4887–4891.
   PubMed Web of Science ®Google Scholar
• Teichmann, M., Z. Wang, M. Ito, K. Seifart, and R. G. Roeder. Unpublished data.
   Google Scholar
• Tzamarias, D., and J. Struhl 1995. Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters. Genes Dev. 9:821–831.
   PubMedGoogle Scholar
• Wang, Z., and J. Roeder 1995. Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains. Proc. Natl. Acad. Sci. USA 92:7026–7030.
   PubMedGoogle Scholar
• Wang, Z., and J. Roeder 1996. TFIIIC1 acts through a downstream region to stabilize TFIIIC2 binding to RNA polymerase III promoters. Mol. Cell. Biol. 16:6841–6850.
   PubMed Web of Science ®Google Scholar
• Wang, Z., T. Lou, and J. Roeder 1997. Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition. Genes Dev. 11:2371–2382.
   PubMed Web of Science ®Google Scholar
• Wang, Z., and J. Roeder 1997. Three human RNA polymerase III specific subunits form a subcomplex with a selective function in specific transcription initiation. Genes Dev. 11:1315–1326.
   PubMed Web of Science ®Google Scholar
• Wang, Z., and J. Roeder 1998. DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III. Mol. Cell 1:749–751.
   PubMed Web of Science ®Google Scholar
• Wang, Z., and R. G. Roeder. Unpublished data.
   Google Scholar
• Werner, M., N. Chaussivert, I. M. Willis, and J. Sentenac 1993. Interaction between a complex of RNA polymerase III subunits and the 70-kDa component of transcription factor IIIB. J. Biol. Chem. 268:20721–20724.
   PubMed Web of Science ®Google Scholar
• White, R. J. 1994. RNA polymerase III transcription. R. G. Landes Co., Austin, Tex.
   Google Scholar
• Willis, I. M. 1993. RNA polymerase III. Genes, factors and transcriptional specificity. Eur. J. Biochem. 212:1–11.
   PubMedGoogle Scholar
• Yoshinaga, S. K., P. A. Boulanger, and J. Berk 1987. Resolution of human transcription factor TFIIIC into two functional components. Proc. Natl. Acad. Sci. USA 84:3585–3589.
   PubMed Web of Science ®Google Scholar
• Yoshinaga, S. K., N. D. L’Etoile, and J. Berk 1989. Purification and characterization of transcription factor IIIC2. J. Biol. Chem. 264:10726–10731.
   PubMedGoogle Scholar