Targeted Expression of the DNA Binding Domain of DRE-Binding Factor, a Drosophila Transcription Factor, Attenuates DNA Replication of the Salivary Gland and Eye Imaginal Disc

REFERENCES

• Brand, A., and J. Perrimon 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotype. Development 118:401–415.
   PubMed Web of Science ®Google Scholar
• Brand, A., and J. Perrimon 1994. Raf acts downstream of the EGF receptor to determine dorso-ventral polarity during Drosophila oogenesis. Genes Dev. 8:629–639.
   PubMedGoogle Scholar
• Cox, K. H., D. Y. DeLeon, L. M. Angerer, and J. Angerer 1984. Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes. Dev. Biol. 101:485–502.
   PubMed Web of Science ®Google Scholar
• Duronio, R. J., P. H. O’Farrell, J. E. Xie, A. Brook, and J. Dyson 1995. The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev. 9:1445–1455.
   PubMed Web of Science ®Google Scholar
• Dynlacht, B. D., A. Brook, M. Dembski, L. Yenush, and J. Dyson 1994. DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Proc. Natl. Acad. Sci. USA 91:6359–6363.
   PubMedGoogle Scholar
• Fischer, J. A., E. Giniger, T. Maniatis, and J. Ptashne 1988. GAL4 activates transcription in Drosophila. Nature 332:853–865.
   PubMed Web of Science ®Google Scholar
• Fuse, N., S. Hirose, and J. Hayashi 1994. Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot. Genes Dev. 8:2270–2281.
   PubMedGoogle Scholar
• Gottlieb, M. T., and J. Oren 1996. p53 in growth control and neoplasia. Biochim. Biophys. Acta 1287:77–102.
   PubMed Web of Science ®Google Scholar
• Hart, C. M., K. Zhao, and J. Laemmli 1997. The scs′ boundary element: characterization of boundary element-associated factors. Mol. Cell. Biol. 17:999–1009.
   PubMedGoogle Scholar
• Hay, B. A., T. Wolff, and J. Rubin 1994. Expression of baculovirus p35 prevents cell death in Drosophila. Development 120:2121–2129.
   PubMed Web of Science ®Google Scholar
• Hayashi, Y., F. Hirose, Y. Nishimoto, M. Shiraki, M. Yamagishi, A. Matsukage, and J. Yamaguchi 1997. Identification of CFDD (common regulatory factor for DNA replication and DREF genes) and role of its binding site in regulation of the proliferating cell nuclear antigen gene promoter. J. Biol. Chem. 272:22848–22858.
   PubMedGoogle Scholar
• Hirose, F., M. Yamaguchi, Y. Nishida, M. Masutani, H. Miyazawa, F. Hanaoka, and J. Matsukage 1991. Structure and expression during development of Drosophila melanogaster gene for DNA polymerase α. Nucleic Acids Res. 19:4991–4998.
   PubMed Web of Science ®Google Scholar
• Hirose, F., M. Yamaguchi, H. Handa, Y. Inomata, and J. Matsukage 1993. Novel 8-bp sequence (DRE) and specific binding factor (DREF) involved in the expression of Drosophila genes for DNA polymerase α and proliferating cell nuclear antigen. J. Biol. Chem. 268:2092–2099.
   PubMed Web of Science ®Google Scholar
• Hirose, F., M. Yamaguchi, and J. Matsukage 1994. Repression of regulatory factor for Drosophila DNA replication-related gene promoters by zerknüllt homeodomain protein. J. Biol. Chem. 269:2937–2942.
   PubMed Web of Science ®Google Scholar
• Hirose, F., M. Yamaguchi, K. Kuroda, A. Omori, T. Hachiya, M. Ikeda, Y. Nishimoto, and J. Matsukage 1996. Isolation and characterization of cDNA for DREF, a promoter-activating factor for Drosophila DNA replication-related genes. J. Biol. Chem. 271:3930–3937.
   PubMedGoogle Scholar
• Matsukage, A., F. Hirose, Y. Hayashi, K. Hamada, and J. Yamaguchi 1995. The DRE sequence TATCGATA, a putative promoter-activating element for Drosophila melanogaster cell proliferation-related genes. Gene 166:233–236.
   PubMedGoogle Scholar
• Mui, A. L., H. Wakao, T. Kinoshita, T. Kitamura, and J. Miyajima 1996. Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation. EMBO J. 15:2425–2433.
   PubMed Web of Science ®Google Scholar
• Nakajima, K., Y. Yamanaka, K. Nakae, H. Kojoma, M. Ichiba, N. Kiuchi, T. Kataoka, T. Fukada, M. Hibi, and J. Hirano 1996. A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells. EMBO J. 15:3651–3658.
   PubMed Web of Science ®Google Scholar
• Ohno, K., F. Hirose, K. Sakaguchi, Y. Nishida, and J. Matsukage 1996. Transcriptional regulation of the Drosophila CycA gene by the DNA replication-related element (DRE) and DRE-binding factor (DREF). Nucleic Acids Res. 24:3942–3946.
   PubMed Web of Science ®Google Scholar
• Ohtani, K., and J. Nevins 1994. Functional properties of a Drosophila homolog of the E2F1 gene. Mol. Cell. Biol. 14:1603–1612.
   PubMed Web of Science ®Google Scholar
• Peterson, N. S. 1990. Effects of heat and chemical stress on development. Adv. Genet. 28:275–296.
   PubMedGoogle Scholar
• Ramos-Onsins, S., C. Segarra, J. Rozas, and J. Aguade 1998. Molecular and chromosomal phylogeny in the obscura group of Drosophila inferred from sequences of the rp49 gene region. Mol. Phylogenet. Evol. 9:22–41.
   Google Scholar
• Robertson, H. M., C. R. Preston, R. W. Philips, D. M. Johnson-Shlitz, W. K. Benz, and J. Engels 1988. A stable genomic source of P-element transposase in Drosophila melanogaster. Genetics 118:461–470.
   PubMed Web of Science ®Google Scholar
• Royzman, I., A. J. Whittaker, and J. Orr-Weaver 1997. Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcription program. Genes Dev. 11:1999–2011.
   PubMedGoogle Scholar
• Ryu, J.-R., T.-Y. Choi, E.-J. Kwon, W.-H. Lee, Y. Nishida, Y. Hayashi, A. Matsukage, M. Yamaguchi, and J. Yoo 1997. Transcriptional regulation of the Drosophila-raf proto-oncogene by the DNA replication-related element (DRE)/DRE-binding factor (DREF) system. Nucleic Acids Res. 25:794–799.
   PubMed Web of Science ®Google Scholar
• Saitou, M., S. Sugai, H. Tanaka, K. Shimouchi, E. Fuchs, S. Narumiya, and J. Kakizuka 1995. Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor. Nature 374:159–162.
   PubMedGoogle Scholar
• Sawado, T., F. Hirose, Y. Takahashi, T. Sasaki, T. Shinomiya, K. Sakaguchi, A. Matsukage, and J. Yamaguchi 1998. Roles of DNA replication related elements (DRE) in regulation of Drosophila E2F (dE2F) gene. J. Biol. Chem. 273:26042–26051.
   PubMedGoogle Scholar
• Sparrow, J. C. 1978. Melanotic “tumours,” The genetics and biology of Drosophila In M. Ashburner, T. W. Wright (ed.), 2b:277–313 Academic Press, London, United Kingdom.
   Google Scholar
• Spradling, A. C. 1986. P element-mediated transformation, p. 175–197. In D. B. Roberts (ed.), Drosophila: a practical approach. IRL Press, Oxford, United Kingdom.
   Google Scholar
• Takahashi, Y., M. Yamaguchi, F. Hirose, S. Cotterill, J. Kobayashi, S. Miyajima, and J. Matsukage 1996. DNA replication-related elements cooperate to enhance promoter activity of the Drosophila DNA polymerase α 73-kDa subunit gene. J. Biol. Chem. 271:14541–14547.
   PubMed Web of Science ®Google Scholar
• Takahashi, Y., F. Hirose, A. Matsukage, and J. Yamaguchi 1999. Identification of three conserved regions in the DREF transcription factors from Drosophila melanogaster and Drosophila virilis. Nucleic Acids Res. 27:510–516.
   PubMed Web of Science ®Google Scholar
• Tarunina, M., and J. Jenkins 1993. Human p53 binds DNA as a protein homodimer but monomeric variants retain full transcription transactivation activity. Oncogene 8:3165–3173.
   PubMedGoogle Scholar
• Waterman, J. L., J. L. Shenk, and J. Halazonetis 1995. The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding. EMBO J. 14:512–519.
   PubMedGoogle Scholar
• Watson, K. L., T. K. Johnson, and J. Denell 1991. Lethal (l) aberrant immune response mutations leading to melanotic tumor formation in Drosophila melanogaster. Dev. Genet. 12:173–187.
   PubMedGoogle Scholar
• Wilder, E. L., and J. Perrimon 1995. Dual function of wingless in the Drosophila leg imaginal disc. Development 121:477–488.
   PubMedGoogle Scholar
• Yamaguchi, M., Y. Hayashi, and J. Matsukage 1995. Essential role of E2F recognition sites in regulation of the proliferating cell nuclear antigen gene promoter during Drosophila development. J. Biol. Chem. 270:25159–25165.
   PubMed Web of Science ®Google Scholar
• Yamaguchi, M., Y. Hayashi, Y. Nishimoto, F. Hirose, and J. Matsukage 1995. A nucleotide sequence essential for the function of DRE, a common promoter element for Drosophila DNA replication-related genes. J. Biol. Chem. 270:15808–15814.
   PubMed Web of Science ®Google Scholar
• Yamaguchi, M., F. Hirose, and J. Matsukage 1996. Roles of multiple promoter elements of the proliferating cell nuclear antigen gene during Drosophila development. Genes Cells 1:47–58.
   PubMedGoogle Scholar
• Zhao, K., C. M. Hart, and J. Laemmli 1995. Visualization of chromosome domains with boundary element-associated factor BEAF-32. Cell 81:879–889.
   PubMedGoogle Scholar