Identification of cis and trans Elements Involved in the Cell Cycle Regulation of Multiple Genes in Crithidia fasciculata

REFERENCES

• Beetham, J. K., K. S. Myung, J. J. McCoy, M. E. Wilson, and J. Donelson 1997. Glycoprotein 46 mRNA abundance is post-transcriptionally regulated during development of Leishmania chagasi promastigotes to an infectious form. J. Biol. Chem. 272:17360–17366.
   PubMedGoogle Scholar
• Berberof, M., L. Vanhamme, P. Tebabi, A. Pays, D. Jefferies, S. Welburn, and J. Pays 1995. The 3′-terminal region of the mRNAs for VSG and procyclin can confer stage specificity to gene expression in Trypanosoma brucei. EMBO J. 14:2925–2934.
   PubMed Web of Science ®Google Scholar
• Bogenhagen, D., and J. Clayton 1977. Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycle. Cell 11:719–727.
   PubMed Web of Science ®Google Scholar
• Brown, L. M., and J. Ray 1997. Cell cycle regulation of RPA1 transcript levels in the trypanosomatid Crithidia fasciculata. Nucleic Acids Res. 25:3281–3289.
   PubMedGoogle Scholar
• Charest, H., W. W. Zhang, and J. Matlashewski 1996. The developmental expression of Leishmania donovani A2 amastigote-specific genes is post-transcriptionally mediated and involves elements located in the 3′-untranslated region. J. Biol. Chem. 271:17081–17090.
   PubMed Web of Science ®Google Scholar
• Chen, X., J. Sadlock, and J. Schon 1993. RNA-binding patterns in total human tissue proteins: analysis by Northwestern blotting. Biochem. Biophys. Res. Commun. 191:18–25.
   PubMedGoogle Scholar
• Cosgrove, W. B., and J. Skeen 1970. The cell cycle in Crithidia fasciculata. Temporal relationships between synthesis of deoxyribonucleic acid in the nucleus and in the kinetoplast. J. Protozool. 17:172–177.
   PubMedGoogle Scholar
• Englund, P. T. 1979. Free minicircles of kinetoplast DNA networks in Crithidia fasciculata. J. Biol. Chem. 254:4895–4900.
   PubMedGoogle Scholar
• Furger, A., N. Schurch, U. Kurath, and J. Roditi 1997. Elements in the 3′ untranslated region of procyclin mRNA regulate expression in insect forms of Trypanosoma brucei by modulating RNA stability and translation. Mol. Cell. Biol. 17:4372–4380.
   PubMed Web of Science ®Google Scholar
• Guttes, E. W., P. C. Hanawalt, and J. Guttes 1967. Mitochondrial DNA synthesis and the mitotic cycle in Physarum polycephalum. Biochim. Biophys. Acta 142:181–194.
   PubMed Web of Science ®Google Scholar
• Hajduk, S. L., V. A. Klein, and J. Englund 1984. Replication of kinetoplast DNA maxicircles. Cell 36:483–492.
   PubMedGoogle Scholar
• Hines, J. C., and J. Ray 1997. Periodic synthesis of kinetoplast DNA topoisomerase II during the cell cycle. Mol. Biochem. Parasitol. 88:249–252.
   PubMedGoogle Scholar
• Hotz, H. R., C. Hartmann, K. Huober, M. Hug, and J. Clayton 1997. Mechanisms of developmental regulation in Trypanosoma brucei: a polypyrimidine tract in the 3′-untranslated region of a surface protein mRNA affects RNA abundance and translation. Nucleic Acids Res. 25:3017–3026.
   PubMedGoogle Scholar
• Hug, M., V. B. Carruthers, C. Hartmann, D. S. Sherman, G. A. Cross, and J. Clayton 1993. A possible role for the 3′-untranslated region in developmental regulation in Trypanosoma brucei. Mol. Biochem. Parasitol. 61:87–95.
   PubMedGoogle Scholar
• Huh, G. S., and J. Hynes 1994. Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element. Genes Dev. 8:1561–1574.
   PubMed Web of Science ®Google Scholar
• Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature (London) 227:680–685.
   PubMed Web of Science ®Google Scholar
• Mahmood, R., and J. Ray 1998. Nuclear extracts of Crithidia fasciculata contain factors that bind to the 5′ untranslated regions of TOP2 and RPA1 mRNAs containing sequences required for their cell cycle regulation. J. Biol. Chem. 273:23729–23734.
   PubMedGoogle Scholar
• Merril, C. R. 1990. Gel-staining techniques. Methods Enzymol. 182:477–488.
   PubMedGoogle Scholar
• Pasion, S. G., G. W. Brown, L. M. Brown, and J. Ray 1994. Periodic expression of nuclear and mitochondrial DNA replication genes during the trypanosomatid cell cycle. J. Cell Sci. 107:3515–3520.
   PubMedGoogle Scholar
• Pasion, S. G., J. C. Hines, X. Ou, R. Mahmood, and J. Ray 1996. Sequences within the 5′ untranslated region regulate the levels of a kinetoplast DNA topoisomerase mRNA during the cell cycle. Mol. Cell. Biol. 16:6724–6735.
   PubMedGoogle Scholar
• Pays, E. 1993. Genome organization and control of gene expression in trypanosomatids, p. 127–160. In P. Broda, S. G. Oliver, P. F. G. Sims (ed.), The eukaryotic genome: organization and regulation. Press Syndicate of the University of Cambridge, Cambridge, United Kingdom.
   Google Scholar
• Ramamoorthy, R., K. G. Swihart, J. J. McCoy, M. E. Wilson, and J. Donelson 1995. Intergenic regions between tandem gp63 genes influence the differential expression of gp63 RNAs in Leishmania chagasi promastigotes. J. Biol. Chem. 270:12133–12139.
   PubMedGoogle Scholar
• Ray, D. S. 1987. Kinetoplast DNA minicircles: high-copy-number mitochondrial plasmids. Plasmid 17:177–190.
   PubMedGoogle Scholar
• Shapiro, T. A., and J. Englund 1995. The structure and replication of kinetoplast DNA. Annu. Rev. Microbiol. 49:117–143.
   PubMed Web of Science ®Google Scholar
• Simpson, L. 1987. The mitochondrial genome of kinetoplastid protozoa: genomic organization, transcription, replication, and evolution. Annu. Rev. Microbiol. 41:363–382.
   PubMedGoogle Scholar
• Stuart, K. 1983. Kinetoplast DNA, mitochondrial DNA with a difference. Mol. Biochem. Parasitol. 9:93–104.
   PubMedGoogle Scholar
• Tacke, R., Y. Chen, and J. Manley 1997. Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: creation of an SRp40-specific splicing enhancer. Proc. Natl. Acad. Sci. USA 94:1148–1153.
   PubMed Web of Science ®Google Scholar
• Tacke, R., and J. Manley 1995. The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities. EMBO J. 14:3540–51.
   PubMed Web of Science ®Google Scholar
• Teixeira, S. M., L. V. Kirchhoff, and J. Donelson 1995. Post-transcriptional elements regulating expression of mRNAs from the amastin/tuzin gene cluster of Trypanosoma cruzi. J. Biol. Chem. 270:22586–22594.
   PubMedGoogle Scholar
• Towbin, H., T. Staehlin, and J. Gordon 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350–4354.
   PubMed Web of Science ®Google Scholar
• Vanhamme, L., and J. Pays 1995. Control of gene expression in trypanosomes. Microbiol. Rev. 59:223–240.
   PubMedGoogle Scholar
• Williamson, D. H., and J. Moustacchi 1971. The synthesis of mitochondrial DNA during the cell cycle in the yeast Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 42:195–201.
   PubMed Web of Science ®Google Scholar