Elevated Cyclin E Levels, Inactive Retinoblastoma Protein, and Suppression of the p27^KIP1 Inhibitor Characterize Early Development of Promyeloid Cells into Macrophages

REFERENCES

• Aagaard-Tillery, K. M., and J. Jelinek 1994. Inhibition of human B lymphocyte cell cycle progression and differentiation by rapamycin. Cell. Immunol. 156:493–507.
   PubMed Web of Science ®Google Scholar
• Aaronson, S. A. 1991. Growth factors and cancer. Science 254:1146–1152.
   PubMed Web of Science ®Google Scholar
• Asiedu, C., J. Biggs, and J. Kraft 1997. Complex regulation of CDK2 during phorbol ester-induced hematopoietic differentiation. Blood 90:3430–3437.
   PubMedGoogle Scholar
• Bartek, J., J. Bartkova, and J. Lukas 1996. The retinoblastoma protein pathway and the restriction point. Curr. Opin. Cell Biol. 8:805–814.
   PubMed Web of Science ®Google Scholar
• Barton, A. E., C. M. Bunce, R. A. Stockley, P. Harrison, and J. Brown 1994. 1α,25-Dihydroxyvitamin D3 promotes monocytopoiesis and suppresses granulocytopoiesis in cultures of normal human myeloid blast cells. J. Leukoc. Biol. 56:124–132.
   PubMedGoogle Scholar
• Baserga, R. 1994. Oncogenes and the strategy of growth factors. Cell 79:927–930.
   PubMed Web of Science ®Google Scholar
• Bergh, G., M. Ehinger, T. Olofsson, B. Baldetorp, E. Johnsson, H. Brycke, G. Lindgren, I. Olsson, and J. Gullberg 1997. Altered expression of the retinoblastoma tumor-suppressor gene in leukemic cell lines inhibits induction of differentiation but not G1-accumulation. Blood 89:2938–2950.
   PubMed Web of Science ®Google Scholar
• Blalock, J. E. 1994. The syntax of immune neuroendocrine communication. Immunol. Today 15:504–511.
   PubMedGoogle Scholar
• Brackman, D., F. Lund-Johansen, and J. Aarskog 1995. Expression of leukocyte differentiation antigens during the differentiation of HL-60 cells induced by 1,25-dihydroxyvitamin D3: comparison with the maturation of normal monocytic and granulocytic bone marrow cells. J. Leukoc. Biol. 58:547–555.
   PubMedGoogle Scholar
• Brugarolas, J., C. Chandrasekaran, J. I. Gordon, D. Beach, T. Jacks, and J. Hannon 1995. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377:552–556.
   PubMed Web of Science ®Google Scholar
• Chen, P. L., D. J. Riley, Y. Chen, and J. Lee 1996. Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. Genes Dev. 10:2794–2804.
   PubMedGoogle Scholar
• Clark, R., J. Strasser, S. McCabe, K. Robbins, and J. Jardieu 1993. Insulin-like growth factor-I stimulation of lymphopoiesis. J. Clin. Investig. 92:540–548.
   PubMed Web of Science ®Google Scholar
• Collins, S. J. 1987. The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood 70:1233–1244.
   PubMed Web of Science ®Google Scholar
• Deng, C., P. Zhang, J. W. Harper, S. J. Elledge, and J. Leder 1995. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82:675–684.
   PubMed Web of Science ®Google Scholar
• Di Cunto, F., G. Topley, E. Calautti, J. Hsiao, L. Ong, P. K. Seth, and J. Dotto 1998. Inhibitory function of p21Cip/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control. Science 280:1069–1071.
   PubMed Web of Science ®Google Scholar
• Farokhzad, O. C., C. M. Shelley, and J. Arnaout 1996. Induction of the CD11b gene during activation of the monocytic cell line U937 requires a novel nuclear factor MS-2. J. Immunol. 157:5597–5605.
   PubMedGoogle Scholar
• Fero, M. L., M. Rivkin, M. Tasch, P. Porter, C. E. Carow, E. Firpo, K. Polyak, L. H. Tsai, V. Broudy, R. M. Perlmutter, K. Kaushansky, and J. Roberts 1996. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27kip1-deficient mice. Cell 85:733–744.
   PubMed Web of Science ®Google Scholar
• Field, S. J., F.-Y. Tsia, F. Kuo, A. M. Zubiaga, W. G. Kaelin, D. M. Livingstone, S. H. Orkin, and J. Greenberg 1996. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 85:549–561.
   PubMed Web of Science ®Google Scholar
• Gibson, L. F., D. Piktel, and J. Landreth 1993. Insulin-like growth factor-I potentiates expansion of interleukin-7-dependent pro-B cells. Blood 82:3005–3011.
   PubMed Web of Science ®Google Scholar
• Gu, W., J. W. Schneider, G. Condorelli, S. Kaushal, V. Mahdavi, and J. Nadal-Ginard 1993. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72:309–324.
   PubMed Web of Science ®Google Scholar
• Halevy, O., B. G. Novitch, D. B. Spicer, S. X. Skapek, J. Rhee, G. J. Hannon, D. Beach, and J. Lassar 1995. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science 267:1081–1021.
   PubMedGoogle Scholar
• Hall, M., and J. Peters 1996. Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Adv. Cancer Res. 68:67–108.
   PubMed Web of Science ®Google Scholar
• Hengst, L., and J. Reed 1996. Translational control of p27Kip1 accumulation during the cell cycle. Science 271:1861–1864.
   PubMed Web of Science ®Google Scholar
• Hodgkin, P. D., J. H. Lee, and J. Lyons 1996. B cell differentiation and isotype switching is related to division cycle number. J. Exp. Med. 184:277–281.
   PubMedGoogle Scholar
• Horowitz, J. M., S.-H. Park, E. Bogenmann, J.-C. Cheng, D. W. Yandell, F. J. Kaye, J. D. Minna, T. P. Dryja, and J. Weinberg 1990. Frequent inactivation of the retinoblastoma antioncogene is restricted to a subset of human tumor cells. Proc. Natl. Acad. Sci. USA 87:2775–2779.
   PubMed Web of Science ®Google Scholar
• Hsieh, T. Y., C. Y. Ng, C. Mallouh, H. Tazaki, and J. Wu 1996. Regulation of growth, PSA/PAP and androgen receptor expression by 1 alpha, 25-dihydroxyvitamin D3 in the androgen-dependent LNCaP cells. Biochem. Biophys. Res. Commun. 223:141–146.
   PubMed Web of Science ®Google Scholar
• Ihle, J. N. 1995. Cytokine receptor signalling. Nature 377:591–594.
   PubMed Web of Science ®Google Scholar
• Jardieu, P., R. Clark, D. Mortensen, and J. Dorshkind 1994. In vivo administration of insulin-like growth factor-I stimulates primary B lymphopoiesis and enhances lymphocyte recovery after bone marrow transplantation. J. Immunol. 152:4320–4327.
   PubMed Web of Science ®Google Scholar
• Juan, G., X. Li, and J. Darzynkiewicz 1998. Phosphorylation of retinoblastoma protein assayed in individual HL-60 cells during their proliferation and differentiation. Exp. Cell Res. 244:83–92.
   PubMedGoogle Scholar
• Kato, J.-Y., M. Matsuoka, K. Polyak, J. Massague, and J. Sherr 1994. Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27kip1) of cyclin-dependent kinase 4 activation. Cell 79:487–496.
   PubMed Web of Science ®Google Scholar
• Kaushansky, K., S. Lok, R. D. Holly, V. Broudy, N. Lin, M. C. Balley, J. W. Forstrom, M. M. Buddle, P. J. Oort, F. S. Hagen, G. J. Roth, T. Papayannopoulou, and J. Foster 1994. Promotion of megakaryocyte progenitor expression and differentiation by the c-Mpl ligand thrombopoietin. Nature 369:568–571.
   PubMed Web of Science ®Google Scholar
• Kimata, H., and J. Fujimoto 1994. Growth hormone and insulin-like growth factor-I induce immunoglobin (Ig) E and IgG4 production by human B cells. J. Exp. Med. 180:727–732.
   PubMedGoogle Scholar
• Kimata, H., and J. Yoshida 1994. Differential effect of growth hormone and insulin-like growth factor-I, insulin-like growth factor-II, and insulin on Ig production and growth in human plasma cells. Blood 83:1569–1574.
   PubMed Web of Science ®Google Scholar
• Kiyokawa, H., R. D. Kineman, K. O. Manova-Todorova, V. C. Soares, E. S. Hoffman, M. Ono, D. Khanam, A. C. Hayday, L. A. Frohman, and J. Koff 1996. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27kip1. Cell 85:721–732.
   PubMed Web of Science ®Google Scholar
• Kooijman, R., E. L. Hooghe-Peters, and J. Hooghe 1996. Prolactin, growth hormone and insulin-like growth factor-I in the immune system. Adv. Immunol. 63:377–454.
   PubMed Web of Science ®Google Scholar
• Lam, E. W., and J. La Thanggue 1996. DP and E2F proteins: coordinating transcription with cell cycle progression. Curr. Opin. Cell Biol. 6:859–866.
   Google Scholar
• Landreth, K. S., R. Narayanan, and J. Dorshkind 1992. Insulin-like growth factor-I regulates pro-B cell differentiation. Blood 80:1207–1212.
   PubMed Web of Science ®Google Scholar
• Lassar, A. B., S. X. Skapek, and J. Novitch 1994. Regulation mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Curr. Opin. Cell Biol. 6:788–794.
   PubMed Web of Science ®Google Scholar
• Levesque, J. P., D. N. Haylock, and J. Simmons 1996. Cytokine regulation of proliferation and cell adhesion are correlated events in human CD34+ hemapoietic progenitors. Blood 88:1168–1176.
   PubMed Web of Science ®Google Scholar
• Li, Y. M., D. H. Schacher, Q. Liu, S. Arkins, N. Rebeiz, R. H. McCusker, R. Dantzer, and J. Kelley 1997. Regulation of myeloid growth and differentiation by the insulin-like growth factor-I receptor. Endocrinology 138:362–368.
   PubMedGoogle Scholar
• Liu, M., M. H. Lee, M. Cohen, M. Bommakanti, and J. Freedman 1996. Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev. 10:142–153.
   PubMed Web of Science ®Google Scholar
• Liu, Q., W. Ning, R. Dantzer, G. G. Freund, and J. Kelley 1998. Activation of protein kinase C-ζ and phosphatidylinositol 3′-kinase and promotion of macrophage differentiation by insulin-like growth factor-I. J. Immunol. 160:1393–1401.
   PubMedGoogle Scholar
• Marx, J. 1995. Cell biology. Cell cycle inhibitors may help brake growth as cells develop. Science 267:963–964.
   PubMedGoogle Scholar
• Minshall, C., S. Arkins, G. G. Freund, and J. Kelley 1996. Requirement for phosphatidylinositol 3′-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor. J. Immunol. 156:939–947.
   PubMedGoogle Scholar
• Minshall, C., S. Arkins, J. Straza, J. Conners, R. Dantzer, G. G. Freund, and J. Kelley 1997. IL-4 and insulin-like growth factor-I inhibit the decline in Bcl-2 and promote the survival of IL-3-deprived myeloid progenitors. J. Immunol. 159:1225–1232.
   PubMed Web of Science ®Google Scholar
• Missero, C., and J. Dotto 1996. p21 WAF1/CIP1 and terminal differentiation control of normal epithelia. Mol. Cell. Differ. 4:1–16.
   Google Scholar
• Miura, M., S. W. Li, G. Dumenil, and J. Baserga 1994. Platelet-derived growth factor-induced expression of messenger RNA for the proliferating cell nuclear antigen requires a functional receptor for the insulin-like growth factor I. Cancer Res. 54:2472–2477.
   PubMedGoogle Scholar
• Murphy, W. J., S. K. Durum, M. R. Anver, and J. Longo 1992. Immunologic and hematologic effects of neuroendocrine hormones: studies on DW/J dwarf mice. J. Immunol. 148:3799–3805.
   PubMed Web of Science ®Google Scholar
• Murphy, W. J., S. K. Durum, and J. Longo 1992. Role of neuroendocrine hormones in murine T cell development. Growth hormone exerts thymopoietic effects in vivo. J. Immunol. 149:3851–3857.
   PubMed Web of Science ®Google Scholar
• Murphy, W. J., G. Tsarfaty, and J. Longo 1992. Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine. Blood 80:1443–1447.
   PubMed Web of Science ®Google Scholar
• Nakayama, K., N. Ishida, M. Shirane, A. Inomata, T. Inoue, N. Shishido, I. Horii, D. Y. Loh, and J. Nakayama 1996. Mice lacking p27kip1 display increased body size, multiple organ hyperplasia, retinal displasia, and pituitary tumors. Cell 85:707–720.
   PubMed Web of Science ®Google Scholar
• Nourse, J., E. Firpo, W. M. Flanagan, S. Coats, K. Polyak, M. H. Lee, J. Massague, G. R. Crabtree, and J. Roberts 1994. Interleukin-2-mediated elimination of the p27kip1 cyclin-dependent kinase inhibitor prevented by rapamycin. Nature 372:570–573.
   PubMed Web of Science ®Google Scholar
• Novitch, B. G., G. J. Mulligan, T. Jacks, and J. Lassar 1996. Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. J. Cell Biol. 135:441–456.
   PubMed Web of Science ®Google Scholar
• Parker, S. B., G. Eichele, P. Zhang, A. Rawls, T. Sands, A. Bradley, E. N. Olson, J. W. Harper, and J. Elledge 1995. p53-independent expression of p21cip1 in muscle and other terminally differentiating cells. Science 267:1024–1027.
   PubMed Web of Science ®Google Scholar
• Reiss, K., P. Porcu, C. Sell, Z. Pietrzkowski, and J. Baserga 1992. The IGF-I receptor is required for the proliferation of hematopoietic cells. Oncogene 7:2243–2248.
   PubMed Web of Science ®Google Scholar
• Roldan, A., E. Charreau, and J. Schillaci 1989. Insulin-like growth factor-I increases the mitogenic response of human peripheral blood lymphocytes to phytohemagglutinin. Immunol. Lett. 20:5–8.
   PubMedGoogle Scholar
• Rosenthal, S. M., and J. Cheng 1995. Opposing early and late effects of insulin-like growth factor I on differentiation and the cell cycle regulatory retinoblastoma protein in skeletal myoblasts. Proc. Natl. Acad. Sci. USA 92:10307–10311.
   PubMed Web of Science ®Google Scholar
• SAS Institute, Inc.. 1989. SAS/STAT user’s guide, version 6, 4th ed. 2: SAS Institute, Inc., Cary, N.C.
   Google Scholar
• Serrano, M., H.-W. Lee, L. Chin, C. Cordon-Cardo, D. Beach, and J. Depinho 1996. Role of the INK4a locus in tumor suppression and cell mortality. Cell 85:27–37.
   PubMed Web of Science ®Google Scholar
• Sherr, C. J. 1996. Cancer cell cycles. Science 274:1672–1677.
   PubMed Web of Science ®Google Scholar
• Shimizu, E., Y. Takahashi, A. Shinohara, Y. Yamamoto, S. Yoshida, A. Yamamoto, S. Sone, Y. Takaue, and J. Ogura 1996. Stem-cell factor regulates the expression of cyclin A and retinoblastoma gene products in the growth and differentiation pathway of human megakaryocytic cells. J. Cancer Res. Clin. Oncol. 122:445–452.
   PubMedGoogle Scholar
• Skapek, S. X., J. Rhee, D. B. Spicer, and J. Lassar 1995. Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D-1-dependent kinase. Science 267:1022–1024.
   PubMed Web of Science ®Google Scholar
• Steinman, R. A., J. Huang, B. Yaroslavskiy, J. P. Goff, E. D. Ball, and J. Nguyen 1998. Regulation of p21(WAF1) expression during normal myeloid differentiation. Blood 91:4531–4542.
   PubMed Web of Science ®Google Scholar
• Taniguchi, T. 1995. Cytokine signaling through nonreceptor protein tyrosine kinases. Science 268:251–255.
   PubMed Web of Science ®Google Scholar
• Thissen, J.-P., J.-M. Ketelslegers, and J. Underwood 1994. Nutritional regulation of insulin-like growth factors. Endocr. Rev. 15:80–94.
   PubMed Web of Science ®Google Scholar
• Wang, Q. M., J. B. Jones, and J. Studzinski 1996. Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells. Cancer Res. 56:264–267.
   PubMed Web of Science ®Google Scholar
• Watanabe, M., Y. Shimamoto, S. Yoshida, K. Suga, Y. Mizuguchi, O. Kohashi, and J. Yamaguchi 1993. Intracellular multiplication of Legionella pneumophila in HL-60 cells differentiated by 1,25-dihydroxyvitamin D3 and the effect of interferon γ. J. Leukoc. Biol. 54:40–46.
   PubMedGoogle Scholar
• Weigent, D. A., and J. Blalock 1991. The production of growth hormone by subpopulations of rat mononuclear leukocytes. Cell. Immunol. 135:55–65.
   PubMed Web of Science ®Google Scholar
• Weigent, D. A., and J. Blalock 1995. Associations between the neuroendocrine and immune systems. J. Leukoc. Biol. 58:137–150.
   PubMedGoogle Scholar
• Yamamoto, K., A. Hirai, T. Ban, J. Saito, K. Tahara, T. Terano, Y. Tamura, Y. Saito, and J. Kitagawa 1996. Thyrotropin induces G1 cyclin expression and accelerates G1 phase after insulin-like growth factor I stimulation in FRTL-5 cells. Endocrinology 137:2036–2042.
   PubMedGoogle Scholar
• Yamasaki, L., T. Jacks, R. Bronson, E. Goillot, E. Harlow, and J. Dyson 1996. Tumor induction and tissue atrophy in mice lacking E2F-1. Cell 85:537–548.
   PubMed Web of Science ®Google Scholar
• Yen, A., M. Williams, J. D. Platko, C. Der, and J. Hisaka 1994. Expression of activated RAF accelerates cell differentiation and RB protein down-regulation but not hypophosphorylation. Eur. J. Cell Biol. 65:103–113.
   PubMed Web of Science ®Google Scholar
• Yen, A., and J. Soong 1996. Retinoic acid-induced RB hypophosphorylation enhanced by CGP 52411, an EGF family tyrosine kinase receptor inhibitor. Eur. J. Cell Biol. 69:327–334.
   PubMed Web of Science ®Google Scholar