REFERENCES
- Ball, J. M., Mulligan, M. J., and Compans, R. W.. 1997. Basolateral sorting of the HIV type 2 and SIV envelope glycoproteins in polarized epithelial cells: role of the cytoplasmic domain. AIDS Res. Hum. Retrovir. 13:665–675
- Bansal, A., and Gierasch, L. M.. 1991. The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation. Cell 67:1195–1201
- Bates, P., Young, J. A., and Varmus, H. E.. 1993. A receptor for subgroup A Rous sarcoma virus is related to the low density lipoprotein receptor. Cell 74:1043–1051
- Boge, M., Wyss, S., Bonifacino, J. S., and Thali, M.. 1998. A membrane-proximal tyrosine-based signal mediates internalization of the HIV-1 envelope glycoprotein via interaction with the AP-2 clathrin adaptor. J. Biol. Chem. 273:15773–15778
- Boll, W., Ohno, H., Songyang, Z., Rapoport, I., Cantley, L. C., Bonifacino, J. S., and Kirchhausen, T.. 1996. Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes. EMBO J. 15:5789–5795
- Bretscher, M. S., Thomson, J. N., and Pearse, B. M.. 1980. Coated pits act as molecular filters. Proc. Natl. Acad. Sci. USA 77:46–49
- Brewer, C. B., and Roth, M. G.. 1991. A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin. J. Cell Biol. 114:413–421
- Brown, M. S., Anderson, R. G., and Goldstein, J. L.. 1983. Recycling receptors: the round-trip itinerary of migrant membrane proteins. Cell 32:663–667
- Chang, C. P., Lazar, C. S., Walsh, B. J., Komuro, M., Collawn, J. F., Kuhn, L. A., Tainer, J. A., Trowbridge, I. S., Farquhar, M. G., Rosenfeld, M. G. et al. 1993. Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J. Biol. Chem. 268:19312–19320
- Chen, W. S., Lazar, C. S., Lund, K. A., Welsh, J. B., Chang, C. P., Walton, G. M., Der, C. J., Wiley, H. S., Gill, G. N., and Rosenfeld, M. G.. 1989. Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell 59:33–43
- Collawn, J. F., Kuhn, L. A., Liu, L. F., Tainer, J. A., and Trowbridge, I. S.. 1991. Transplanted LDL and mannose-6-phosphate receptor internalization signals promote high-efficiency endocytosis of the transferrin receptor. EMBO J. 10:3247–3253
- Collawn, J. F., Stangel, M., Kuhn, L. A., Esekogwu, V., Jing, S. Q., Trowbridge, I. S., and Tainer, J. A.. 1990. Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis. Cell 63:1061–1072
- Davis, G. L., and Hunter, E.. 1987. A charged amino acid substitution within the transmembrane anchor of the Rous sarcoma virus envelope glycoprotein affects surface expression but not intracellular transport. J. Cell Biol. 105:1191–1203
- Dong, J., Roth, M. G., and Hunter, E.. 1992. A chimeric avian retrovirus containing the influenza virus hemagglutinin gene has an expanded host range. J. Virol. 66:7374–7382
- Dong, J. Y., Dubay, J. W., Perez, L. G., and Hunter, E.. 1992. Mutations within the proteolytic cleavage site of the Rous sarcoma virus glycoprotein define a requirement for dibasic residues for intracellular cleavage. J. Virol. 66:865–874
- Dubay, J. W., Roberts, S. J., Hahn, B. H., and Hunter, E.. 1992. Truncation of the human immunodeficiency virus type 1 transmembrane glycoprotein cytoplasmic domain blocks virus infectivity. J. Virol. 66:6616–6625
- Eberle, W., Sander, C., Klaus, W., Schmidt, B., von Figura, K., and Peters, C.. 1991. The essential tyrosine of the internalization signal in lysosomal acid phosphatase is part of a beta turn. Cell 67:1203–1209
- Egan, M. A., Carruth, L. M., Rowell, J. F., Yu, X., and Siliciano, R. F.. 1996. Human immunodeficiency virus type 1 envelope protein endocytosis mediated by a highly conserved intrinsic internalization signal in the cytoplasmic domain of gp41 is suppressed in the presence of the Pr55gag precursor protein. J. Virol. 70:6547–6556
- Geffen, I., Fuhrer, C., Leitinger, B., Weiss, M., Huggel, K., Griffiths, G., and Spiess, M.. 1993. Related signals for endocytosis and basolateral sorting of the asialoglycoprotein receptor. J. Biol. Chem. 268:20772–20777
- Ghosh, R. N., Mallet, W. G., Soe, T. T., McGraw, T. E., and Maxfield, F. R.. 1998. An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells. J. Cell Biol. 142:923–936
- Gottlieb, T. A., Ivanov, I. E., Adesnik, M., and Sabatini, D. D.. 1993. Actin microfilaments play a critical role in endocytosis at the apical but not the basolateral surface of polarized epithelial cells. J. Cell Biol. 120:695–710
- Griffiths, G., Back, R., and Marsh, M.. 1989. A quantitative analysis of the endocytic pathway in baby hamster kidney cells. J. Cell Biol. 109:2703–2720
- Hunziker, W., and Fumey, C.. 1994. A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells. EMBO J. 13:2963–2967
- Jing, S., and Trowbridge, I.. 1990. Nonacylated human transferrin receptors are rapidly internalized and mediate iron uptake. J. Biol. Chem. 265:11555–11559
- Jing, S. Q., Spencer, T., Miller, K., Hopkins, C., and Trowbridge, I. S.. 1990. Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization. J. Cell Biol. 110:283–294
- Johnson, L. S., Dunn, K. W., Pytowski, B., and McGraw, T. E.. 1993. Endosome acidification and receptor trafficking: bafilomycin A1 slows receptor externalization by a mechanism involving the receptor's internalization motif. Mol. Biol. Cell 4:1251–1266
- Johnston, P. B., Dong, J. Y., and Hunter, E.. 1995. Transport of a lysosomally targeted Rous sarcoma virus envelope glycoprotein involves transient expression on the cell surface. Virology 206:353–361
- Kang, S., Liang, L., Parker, C. D., and Collawn, J. F.. 1998. Structural requirements for major histocompatibility complex class II invariant chain endocytosis and lysosomal targeting. J. Biol. Chem. 273:20644–20652
- Katz, R. A., Omer, C. A., Weis, J. H., Mitsialis, S. A., Faras, A. J., and Guntaka, R. V.. 1982. Restriction endonuclease and nucleotide sequence analysis of molecularly cloned unintegrated avian tumor virus DNA: structure of large terminal repeats in circular junctions. J. Virol. 42:346–351
- Ktistakis, N. T., Thomas, D., and Roth, M. G.. 1990. Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins. J. Cell Biol. 111:1393–1407
- LaBranche, C. C., Sauter, M. M., Haggarty, B. S., Vance, P. J., Romano, J., Hart, T. K., Bugelski, P. J., Marsh, M., and Hoxie, J. A.. 1995. A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells. J. Virol. 69:5217–5227
- Lazarovits, J., Naim, H. Y., Rodriguez, A. C., Wang, R. H., Fire, E., Bird, C., Henis, Y. I., and Roth, M. G.. 1996. Endocytosis of chimeric influenza virus hemagglutinin proteins that lack a cytoplasmic recognition feature for coated pits. J. Cell Biol. 134:339–348
- Lazarovits, J., and Roth, M.. 1988. A single amino acid change in the cytoplasmic domain allows the influenza virus hemagglutinin to be endocytosed through coated pits. Cell 53:743–752
- Lazarovits, J., Shia, S. P., Ktistakis, N., Lee, M. S., Bird, C., and Roth, M. G.. 1990. The effects of foreign transmembrane domains on the biosynthesis of the influenza virus hemagglutinin. J. Biol. Chem. 265:4760–4767
- Lin, S., Naim, H. Y., and Roth, M. G.. 1997. Tyrosine-dependent basolateral sorting signals are distinct from tyrosine-dependent internalization signals. J. Biol. Chem. 272:26300–26305
- Lippincott-Schwartz, J., and Fambrough, D. M.. 1987. Cycling of the integral membrane glycoprotein, LEP100, between plasma membrane and lysosomes: kinetic and morphological analysis. Cell 49:669–677
- Lodge, R., Göttlinger, H., Gabuzda, D., Cohen, E. A., and Lemay, G.. 1994. The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells. J. Virol. 68:4857–4861
- Lodge, R., Lalonde, J. P., Lemay, G., and Cohen, E. A.. 1997. The membrane-proximal intracytoplasmic tyrosine residue of HIV-1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells. EMBO J. 16:695–705
- Mayor, S., Presley, J. F., and Maxfield, F. R.. 1993. Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. J. Cell Biol. 121:1257–1269
- Melkonian, K. A., Ostermeyer, A. G., Chen, J. Z., Roth, M. G., and Brown, D. A.. 1999. Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated. J. Biol. Chem. 274:3910–3917
- Mukherjee, S., Ghosh, R. N., and Maxfield, F. R.. 1997. Endocytosis. Physiol. Rev. 77:759–803
- Ohno, H., Aguilar, R. C., Fournier, M. C., Hennecke, S., Cosson, P., and Bonifacino, J. S.. 1997. Interaction of endocytic signals from the HIV-1 envelope glycoprotein complex with members of the adaptor medium chain family. Virology 238:305–315
- Ohno, H., Stewart, J., Fournier, M. C., Bosshart, H., Rhee, I., Miyatake, S., Saito, T., Gallusser, A., Kirchhausen, T., and Bonifacino, J. S.. 1995. Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science 269:1872–1875
- Olson, J. K., and Grose, C.. 1997. Endocytosis and recycling of varicella-zoster virus Fc receptor glycoprotein gE: internalization mediated by a YXXL motif in the cytoplasmic tail. J. Virol. 71:4042–4054
- Owens, R. J., and Compans, R. W.. 1989. Expression of the human immunodeficiency virus envelope glycoprotein is restricted to basolateral surfaces of polarized epithelial cells. J. Virol. 63:978–982
- Owens, R. J., Dubay, J. W., Hunter, E., and Compans, R. W.. 1991. Human immunodeficiency virus envelope protein determines the site of virus release in polarized epithelial cells. Proc. Natl. Acad. Sci. USA 88:3987–3991
- Pelchen-Matthews, A., Armes, J. E., Griffiths, G., and Marsh, M.. 1991. Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells. J. Exp. Med. 173:575–587
- Pelchen-Matthews, A., Boulet, I., Littman, D. R., Fagard, R., and Marsh, M.. 1992. The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits. J. Cell Biol. 117:279–290
- Pelchen-Matthews, A., Clapham, P., and Marsh, M.. 1995. Role of CD4 endocytosis in human immunodeficiency virus infection. J. Virol. 69:8164–8168
- Pelchen-Matthews, A., Parsons, I. J., and Marsh, M.. 1993. Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting. J. Exp. Med. 178:1209–1222
- Pipas, J. M., Peden, K. W. C., and Nathans, D.. 1983. Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene. Mol. Cell. Biol. 3:203–213
- Pytowski, B., Judge, T. W., and McGraw, T. E.. 1995. An internalization motif is created in the cytoplasmic domain of the transferrin receptor by substitution of a tyrosine at the first position of a predicted tight turn. J. Biol. Chem. 270:9067–9073
- Reaves, B. J., Banting, G., and Luzio, J. P.. 1998. Lumenal and transmembrane domains play a role in sorting type I membrane proteins on endocytic pathways. Mol. Biol. Cell 9:1107–1122
- Rohrer, J., Schweizer, A., Russell, D., and Kornfeld, S.. 1996. The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane. J. Cell Biol. 132:565–576
- Roth, M. G., Doyle, C., Sambrook, J., and Gething, M. J.. 1986. Heterologous transmembrane and cytoplasmic domains direct functional chimeric influenza virus hemagglutinins into the endocytic pathway. J. Cell Biol. 102:1271–1283
- Rowell, J. F., Stanhope, P. E., and Siliciano, R. F.. 1995. Endocytosis of endogenously synthesized HIV-1 envelope protein. J. Immunol. 155:473–488
- Sauter, M. M., Pelchen-Matthews, A., Bron, R., Marsh, M., LaBranche, C. C., Vance, P. J., Romano, J., Haggarty, B. S., Hart, T. K., Lee, W. M., and Hoxie, J. A.. 1996. An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface. J. Cell Biol. 132:795–811
- Scheiffele, P., Roth, M. G., and Simons, K.. 1997. Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain. EMBO J. 16:5501–5508
- Signoret, N., Oldridge, J., Pelchen-Matthews, A., Klasse, P. J., Tran, T., Brass, L. F., Rosenkilde, M. M., Schwartz, T. W., Holmes, W., Dallas, W., Luther, M. A., Wells, T. N., Hoxie, J. A., and Marsh, M.. 1997. Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4. J. Cell Biol. 139:651–664
- Stephens, D. J., and Banting, G.. 1998. Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120. Biochem. J. 335:567–572
- Thomas, D. C., Brewer, C. B., and Roth, M. G.. 1993. Vesicular stomatitis virus glycoprotein contains a dominant cytoplasmic basolateral sorting signal critically dependent upon a tyrosine. J. Biol. Chem. 268:3313–3320
- Thomas, D. C., and Roth, M. G.. 1994. The basolateral targeting signal in the cytoplasmic domain of glycoprotein G from vesicular stomatitis virus resembles a variety of intracellular targeting motifs related by primary sequence but having diverse targeting activities. J. Biol. Chem. 269:15732–15739
- Trowbridge, I. S., Collawn, J. F., and Hopkins, C. R.. 1993. Signal-dependent membrane protein trafficking in the endocytic pathway. Annu. Rev. Cell Biol. 9:129–161
- Watts, C., and Marsh, M.. 1992. Endocytosis: what goes in and how? J. Cell Sci. 103:1–8
- White, S., Hatton, S. R., Siddiqui, M. A., Parker, C. D., Trowbridge, I. S., and Collawn, J. F.. 1998. Analysis of the structural requirements for lysosomal membrane targeting using transferrin receptor chimeras. J. Biol. Chem. 273:14355–14362
- Young, J. A., Bates, P., and Varmus, H. E.. 1993. Isolation of a chicken gene that confers susceptibility to infection by subgroup A avian leukosis and sarcoma viruses. J. Virol. 67:1811–1816