Nuclear Export of Heat Shock and Non-Heat-Shock mRNA Occurs via Similar Pathways

REFERENCES

• Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K.. 1994. Current protocols in molecular biology. John Wiley and Sons, Inc., New York, N.Y
   Google Scholar
• Carazo-Salas, R. E., Guarguaglini, G., Gruss, O. J., Segref, A., Karsenti, E., and Mattaj, I. W.. 1999. Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 400:178–181
   PubMed Web of Science ®Google Scholar
• Corbett, A. H., Koepp, D. M., Schlenstedt, G., Lee, M. S., Hopper, A. K., and Silver, P. A.. 1995. Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import. J. Cell Biol. 130:1017–1026
   PubMedGoogle Scholar
• Doye, V., and Hurt, E.. 1997. From nucleoporins to nuclear pore complexes. Curr. Opin. Cell Biol. 9:401–411
   PubMed Web of Science ®Google Scholar
• Doye, V., Wepf, R., and Hurt, E. C.. 1994. A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution. EMBO J. 13:6062–6075
   PubMed Web of Science ®Google Scholar
• Dreyfuss, G., Matunis, M. J., Piñol-Roma, S., and Burd, C. G.. 1993. hnRNP proteins and the biogenesis of mRNA. Annu. Rev. Biochem. 62:289–321
   PubMed Web of Science ®Google Scholar
• Floer, M., and Blobel, G.. 1999. Putative reaction intermediates in Crm1-mediated nuclear protein export. J. Biol. Cell 274:16279–16286
   Google Scholar
• Forrester, W., Stutz, F., Rosbash, M., and Wickens, M.. 1992. Defects in mRNA 3′-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure. Genes Dev. 6:1914–1926
   PubMedGoogle Scholar
• Gorlich, D.. 1998. Transport into and out of the cell nucleus. EMBO J. 17:2721–2727
   PubMed Web of Science ®Google Scholar
• Gorsch, L. C., Dockendorff, T. C., and Cole, C. N.. 1995. A conditional allele of the novel repeat-containing yeast nucleoporin RAT7/NUP159 causes both rapid cessation of mRNA export and reversible clustering of nuclear pore complexes. J. Cell Biol. 129:939–955
   PubMedGoogle Scholar
• Graves, L. E., Segal, S., and Goodwin, E. B.. 1999. TRA-1 regulates the cellular distribution of the tra-2 mRNA in C. Elegans. Nature 399:802–805
   PubMedGoogle Scholar
• Gruter, P., Tabernero, C., von Kobbe, C., Schmitt, C., Saavedra, C., Bachi, A., Wilm, M., Felber, B. K., and Izaurralde, E.. 1998. TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus. Mol. Cell 1:649–659
   PubMed Web of Science ®Google Scholar
• Guthrie, C., and Fink, G. R.. 1991. Guide to yeast genetics and molecular biology. Methods Enzymol. 194:389–398
   PubMedGoogle Scholar
• Huang, Y., Wilmer, K. M., and Carmichael, G. G.. 1998. Intronless mRNA transport elements may affect multiple steps in pre-mRNA processing. EMBO J. 18:1642–1652
   Google Scholar
• Hurt, E., Sträßer, K., Segref, A., Bailer, S., Schlaich, N., Presutti, C., Tollervey, D., and Jansen, R.. 2000. Mex67p mediates nuclear export of a variety of RNA polymerase II transcripts. J. Biol. Chem. 275:8361–8368
   PubMed Web of Science ®Google Scholar
• Hurwitz, M. E., Strambio-de-Castillia, C., and Blobel, G.. 1998. Two yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically orientated subcomplex. Proc. Natl. Acad. Sci. USA 95:11241–11245
   PubMedGoogle Scholar
• Izaurralde, E., Jarmolowski, A., Beisel, C., Mattaj, I. W., Dreyfuss, G., and Fischer, U.. 1997. A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export. J. Cell Biol. 137:27–35
   PubMedGoogle Scholar
• Izaurralde, E., Kutay, U., von Kobbe, C., Mattaj, I. W., and Gorlich, D.. 1997. The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J. 16:6535–6547
   PubMedGoogle Scholar
• Jarmolowski, A., Boelens, W. C., Izaurralde, E., and Mattaj, I. W.. 1994. Nuclear export of different classes of RNA is mediated by specific factors. J. Cell Biol. 124:627–635
   PubMed Web of Science ®Google Scholar
• Katahira, J., Strasser, K., Podtelenikov, A., Mann, M., Jung, J. U., and Hurt, E.. 1999. The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. EMBO J. 18:2593–2609
   PubMed Web of Science ®Google Scholar
• Koepp, D. M., Wong, D. H., Corbett, A. H., and Silver, P. A.. 1996. Dynamic localization of the nuclear import receptor and its interactions with transport factors. J. Cell Biol. 133:1163–1176
   PubMed Web of Science ®Google Scholar
• Krebber, H., Taura, T., Lee, M. S., and Silver, P. A.. 1999. Uncoupling of the hnRNP Np13p from mRNA during the stress-induced block in mRNA export. Genes Dev. 13:1994–2004
   PubMedGoogle Scholar
• Legrain, P., and Rosbash, M.. 1989. Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm. Cell 57:573–583
   PubMed Web of Science ®Google Scholar
• Long, R. M., Singer, R. H., Meng, X., Gonzalez, I., Nasmyth, K., and Jansen, R.. 2000. Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. Science 277:383–387
   Google Scholar
• MacMorris, M. A., Zorio, D. A., and Blumenthal, T.. 1999. An exon that prevents transport of a mature RNA. Proc. Natl. Acad. Sci. USA 7:3813–3818
   Google Scholar
• Maniatis, T., Fritsch, E. F., and Sambrook, J.. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
   Google Scholar
• Mattaj, I. W., and Englmeier, L.. 1998. Nucleocytoplasmic transport: the soluble phase. Annu. Rev. Biochem. 67:265–306
   PubMed Web of Science ®Google Scholar
• Nachury, M. V., and Weis, K.. 1999. The direction of transport through the nuclear pore can be inverted. Proc. Natl. Acad. Sci. USA 96:9622–9627
   PubMed Web of Science ®Google Scholar
• Nakielny, S., and Dreyfuss, G.. 1997. Nuclear export of proteins and RNAs. Curr. Opin. Cell Biol. 9:420–429
   PubMedGoogle Scholar
• Nakielny, S., Fischer, W. M., and Dreyfuss, G.. 1997. RNA Transport. Annu. Rev. Neurosci. 20:269–301
   PubMed Web of Science ®Google Scholar
• Neville, M., Lee, L., Stutz, F., Davis, L. I., and Rosbash, M.. 1997. Evidence that the importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export in S. cerevisiae. Curr. Biol. 7:767–775
   PubMed Web of Science ®Google Scholar
• Neville, M., and Rosbash, M.. 1999. The NES-Crm1p export pathway is not a major mRNA export route in Saccharomyces cerevisiae. EMBO J. 18:3746–3756
   PubMed Web of Science ®Google Scholar
• Nigg, E. A.. 1997. Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature 386:779–787
   PubMed Web of Science ®Google Scholar
• Ohno, M., Fornerod, M., and Mattaj, I. W.. 1998. Nucleocytoplasmic transport: the last 200 nanometers. Cell 92:327–336
   PubMed Web of Science ®Google Scholar
• Pasquinelli, A. E., Powers, M. A., Forbes, D., and Dahlberg, J. E.. 1997. Inhibition of mRNA export in vertebrate cells by nuclear export signal conjugates. Proc. Natl. Acad. Sci. USA 94:14394–14399
   PubMed Web of Science ®Google Scholar
• Pikielny, C. W., and Rosbash, M.. 1985. mRNA splicing efficiency in yeast and the contribution of nonconserved sequences. Cell 41:119–126
   PubMed Web of Science ®Google Scholar
• Rout, M. P., and Blobel, G.. 1993. Isolation of the yeast nuclear pore complex. J. Cell Biol. 123:771–783
   PubMed Web of Science ®Google Scholar
• Saavedra, C., Felber, B., and Izaurralde, E.. 1997. The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export. Curr. Biol. 7:619–628
   PubMed Web of Science ®Google Scholar
• Saavedra, C., Tung, K.-S., Amberg, D. C., Hopper, A. K., and Cole, C. N.. 1996. Regulation of mRNA export in response to stress in Saccharomyces cerevisiae. Genes Dev. 10:1608–1620
   PubMed Web of Science ®Google Scholar
• Saavedra, C. A., Hammell, C. M., Heath, C. V., and Cole, C. N.. 1997. Yeast heat shock mRNAs are exported through a distinct pathway defined by Rip1p. Genes Dev. 11:2845–2856
   PubMedGoogle Scholar
• Santos-Rosa, H., Moreno, H., Simos, G., Segref, A., Fahrenkrog, B., Pante, N., and Hurt, E.. 1998. Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores. Mol. Cell. Biol. 18:6826–6838
   PubMed Web of Science ®Google Scholar
• Seedorf, M., and Silver, P. A.. 1997. Importin/karyopherin protein family members required for mRNA export from the nucleus. Proc. Natl. Acad. Sci. USA 94:8590–8595
   PubMedGoogle Scholar
• Segref, A., Sharma, K., Doye, V., Hellwig, A., Huber, J., Luhrmann, R., and Hurt, E.. 1997. Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores. EMBO J. 16:3256–3271
   PubMed Web of Science ®Google Scholar
• Snay-Hodge, C. A., Colot, H. V., Goldstein, A. L., and Cole, C. N.. 1998. Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export. EMBO J. 17:2663–2676
   PubMedGoogle Scholar
• Stade, K., Ford, C. S., Guthrie, C., and Weis, K.. 1997. Exportin 1 (Crm1p) is an essential nuclear export factor. Cell 90:1041–1050
   PubMed Web of Science ®Google Scholar
• Strahm, Y., Fahrenkrog, B., Zenklusen, D., Rychner, E., Kantor, J., Rosbash, M., and Stutz, F.. 1999. The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr255p. EMBO J. 18:5761–5777
   PubMed Web of Science ®Google Scholar
• Stutz, F., Izaurralde, E., Mattaj, I. W., and Rosbash, M.. 1996. A role for nucleoporin FG repeat domains in export of human immunodeficiency virus type 1 Rev protein and RNA from the nucleus. Mol. Cell. Biol. 16:7144–7150
   PubMedGoogle Scholar
• Stutz, F., Kantor, J., Zhang, D., McCarthy, T., Neville, M., and Rosbash, M.. 1997. The yeast nucleoporin Rip1p contributes to multiple export pathways with no essential role for its FG-repeat region. Genes Dev. 11:2857–2868
   PubMedGoogle Scholar
• Stutz, F., Neville, M., and Rosbash, M.. 1995. Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast. Cell 82:495–506
   PubMedGoogle Scholar
• Stutz, F., and Rosbash, M.. 1998. Nuclear RNA export. Genes Dev. 12:3303–3319
   PubMedGoogle Scholar
• Taura, T., Schlenstedt, G., and Silver, P. A.. 1997. Yrb2b is a nuclear protein that interacts with Prp20p. J. Biol. Chem. 272:31877–31884
   PubMedGoogle Scholar
• Wente, S., and Blobel, G.. 1994. NUP145 encodes a novel yeast glycine-leucine-phenylalanine-glycine (GLFG) nucleoporin required for nuclear envelope structure. J. Cell Biol. 125:955–969
   PubMedGoogle Scholar
• Yang, Q., Rout, M. P., and Akey, C. W.. 1998. Three-dimensional architecture of the isolated yeast nuclear pore complex: functional and evolutionary implications. Mol. Cell 1:223–234
   PubMed Web of Science ®Google Scholar