Functional Characterization of the X-Linked Inhibitor of Apoptosis (XIAP) Internal Ribosome Entry Site Element: Role of La Autoantigen in XIAP Translation

REFERENCES

• Ali, N., and Siddiqui, A.. 1997. The La antigen binds 5′ noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation. Proc. Natl. Acad. Sci. USA 94:2249–2254
   PubMed Web of Science ®Google Scholar
• Bachmann, M., Chang, S., Slor, H., Kukulies, J., and Muller, W. E.. 1990. Shuttling of the autoantigen La between nucleus and cell surface after uv irradiation of human keratinocytes. Exp. Cell Res 191:171–180
   PubMed Web of Science ®Google Scholar
• Bachmann, M., Falke, D., Schroder, H. C., and Muller, W. E.. 1989. Intracellular distribution of the La antigen in CV-1 cells after herpes simplex virus type 1 infection compared with the localization of U small nuclear ribonucleoprotein particles. J. Gen. Virol. 70:881–891
   PubMed Web of Science ®Google Scholar
• Bai, C., and Tolias, P. P.. 2000. Genetic analysis of a La homolog in drosophila melanogaster. Nucleic Acids Res. 28:1078–1084
   PubMed Web of Science ®Google Scholar
• Belsham, G. J., and Sonenberg, N.. 1996. RNA-protein interactions in regulation of picornavirus RNA translation. Microbiol. Rev. 60:499–511
   PubMedGoogle Scholar
• Belsham, G. J., Sonenberg, N., and Svitkin, Y. V.. 1995. The role of the La autoantigen in internal initiation. Curr. Top. Microbiol. Immunol. 203:85–98
   PubMed Web of Science ®Google Scholar
• Blyn, L. B., Towner, J. S., Semler, B. L., and Ehrenfeld, E.. 1997. Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA. J. Virol. 71:6243–6246
   PubMed Web of Science ®Google Scholar
• Chan, E. K., and Tan, E. M.. 1987. Human autoantibody-reactive epitopes of SS-B/La are highly conserved in comparison with epitopes recognized by murine monoclonal antibodies. J. Exp. Med. 166:1627–1640
   PubMed Web of Science ®Google Scholar
• Craig, A. W., Svitkin, Y. V., Lee, H. S., Belsham, G. J., and Sonenberg, N.. 1997. The La autoantigen contains a dimerization domain that is essential for enhancing translation. Mol. Cell. Biol. 17:163–169
   PubMed Web of Science ®Google Scholar
• Deveraux, Q. L., Takahashi, R., Salvesen, G. S., and Reed, J. C.. 1997. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388:300–304
   PubMed Web of Science ®Google Scholar
• Ehrenfeld, E.. 1996. Initiation of translation by picornavirus RNAs Translational control. Hershey, J. W. B., Mathews, M. B., and Sonenberg, N. 549–573 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
   Google Scholar
• Fan, H., Goodier, J. L., Chamberlain, J. R., Engelke, D. R., and Maraia, R. J.. 1998. 5′ processing of tRNA precursors can Be modulated by the human La antigen phosphoprotein. Mol. Cell. Biol. 18:3201–3211
   PubMed Web of Science ®Google Scholar
• Farahani, R., Fong, W. G., Korneluk, R. G., and MacKenzie, A. E.. 1997. Genomic organization and primary characterization of miap-3: the murine homologue of human X-linked IAP. Genomics 42:514–518
   PubMed Web of Science ®Google Scholar
• Frangioni, J. V., and Neel, B. G.. 1993. Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins. Anal. Biochem. 210:179–187
   PubMed Web of Science ®Google Scholar
• Gottlieb, E., and Steitz, J. A.. 1989. Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III. EMBO J. 8:851–861
   PubMed Web of Science ®Google Scholar
• Gradi, A., Svitkin, Y. V., Imataka, H., and Sonenberg, N.. 1998. Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection. Proc. Natl. Acad. Sci. USA 95:11089–11094
   PubMedGoogle Scholar
• Hellen, C. U., Witherell, G. W., Schmid, M., Shin, S. H., Pestova, T. V., Gil, A., and Wimmer, E.. 1993. A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proc. Natl. Acad. Sci. USA 90:7642–7646
   PubMedGoogle Scholar
• Holcik, M., Lefebvre, C. A., Yeh, C., Chow, T., and Korneluk, R. G.. 1999. A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection. Nat. Cell Biol. 1:190–192
   PubMed Web of Science ®Google Scholar
• Holcik, M., and Liebhaber, S. A.. 1997. Analysis of mRNP complexes assembled in vitro mRNA formation and function. Richter, J. 195–209 Academic Press, New York, N.Y
   Google Scholar
• Holcik, M., and Liebhaber, S. A.. 1997. Four highly stable eukaryotic mRNAs assemble 3′ untranslated region RNA-protein complexes sharing cis and trans components. Proc. Natl. Acad. Sci. USA 94:2410–2414
   PubMed Web of Science ®Google Scholar
• Huez, I., Creancier, L., Audigier, S., Gensac, M. C., Prats, A. C., and Prats, H.. 1998. Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA. Mol. Cell. Biol. 18:6178–6190
   PubMed Web of Science ®Google Scholar
• Isoyama, T., Kamoshita, N., Yasui, K., Iwai, A., Shiroki, K., Toyoda, H., Yamada, A., Takasaki, Y., and Nomoto, A.. 1999. Lower concentration of La protein required for internal ribosome entry on hepatitis C virus RNA than on poliovirus RNA. J. Gen. Virol. 80:2319–2327
   PubMedGoogle Scholar
• Jackson, R. J.. 1996. A comparative view of initiation site selection mechanisms Translational control. Hershey, J. W. B., Mathews, M. B., and Sonenberg, N. 71–112 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
   Google Scholar
• Kenan, D. J., Query, C. C., and Keene, J. D.. 1991. RNA recognition: towards identifying determinants of specificity. Trends Biochem. Sci. 16:214–220
   PubMedGoogle Scholar
• Kiledjian, M., Wang, X., and Liebhaber, S. A.. 1995. Identification of two KH domain proteins in the alpha-globin mRNP stability complex. EMBO J. 14:4357–4364
   PubMed Web of Science ®Google Scholar
• Kim, Y. K., and Jang, S. K.. 1999. La protein is required for efficient translation driven by encephalomyocarditis virus internal ribosomal entry site. J. Gen. Virol. 80:3159–3166
   PubMedGoogle Scholar
• LaCasse, E. C., Baird, S., Korneluk, R. G., and MacKenzie, A. E.. 1998. The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 17:3247–3259
   PubMed Web of Science ®Google Scholar
• Liston, P., Lefebvre, C., Fong, W. G., Xuan, J. Y., and Korneluk, R. G.. 1997. Genomic characterization of the mouse inhibitor of apoptosis protein-1 and 2 genes. Genomics 46:495–503
   PubMedGoogle Scholar
• Liston, P., Roy, N., Tamai, K., Lefebvre, C., Baird, S., Cherton-Horvat, G., Farahani, R., McLean, M., Ikeda, J. E., MacKenzie, A., and Korneluk, R. G.. 1996. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature 379:349–353
   PubMed Web of Science ®Google Scholar
• Liston, P., Young, S. S., Mackenzie, A. E., and Korneluk, R. G.. 1997. Life and death decisions: the role of the IAPs in modulating programmed cell death. Apoptosis 2:423–441
   PubMedGoogle Scholar
• Macejak, D. G., and Sarnow, P.. 1991. Internal initiation of translation mediated by the 5′ leader of a cellular mRNA. Nature 353:90–94
   PubMed Web of Science ®Google Scholar
• MacGregor, G. R., Nolan, G. P., Fiering, S., Roederer, M., and Herzenberg, L. A.. Use of E. coli lacZ (β-galactosidase) as a reporter gene Methods in molecular biology Murray, E. J., and Walker, J. M. 7:217–235 Humana Press Inc., Clifton, N.J
   PubMedGoogle Scholar
• Maraia, R. J.. 1996. 1991. Transcription termination factor La is also an initiation factor for RNA polymerase III. Proc. Natl. Acad. Sci. USA 93:3383–3387
   PubMed Web of Science ®Google Scholar
• Matunis, M. J., Michael, W. M., and Dreyfuss, G.. 1992. Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein. Mol. Cell. Biol. 12:164–171
   PubMed Web of Science ®Google Scholar
• McBratney, S., Chen, C. Y., and Sarnow, P.. 1993. Internal initiation of translation. Curr. Opin. Cell. Biol. 5:961–965
   PubMedGoogle Scholar
• Meerovitch, K., Svitkin, Y. V., Lee, H. S., Lejbkowicz, F., Kenan, D. J., Chan, E. K., Agol, V. I., Keene, J. D., and Sonenberg, N.. 1993. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J. Virol. 67:3798–3807
   PubMed Web of Science ®Google Scholar
• Nanbru, C., Lafon, I., Audigier, S., Gensac, M. C., Vagner, S., Huez, G., and Prats, A. C.. 1997. Alternative translation of the proto-oncogene c-myc by an internal ribosome entry site. J. Biol. Chem. 272:32061–32066
   PubMed Web of Science ®Google Scholar
• Oh, S. K., Scott, M. P., and Sarnow, P.. 1992. Homeotic gene Antennapedia mRNA contains 5′-noncoding sequences that confer translational initiation by internal ribosome binding. Genes Dev. 6:1643–1653
   PubMedGoogle Scholar
• Pelletier, J., and Sonenberg, N.. 1988. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature 334:320–325
   PubMed Web of Science ®Google Scholar
• Pestova, T. V., Hellen, C. U., and Shatsky, I. N.. 1996. Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry. Mol. Cell. Biol. 16:6859–6869
   PubMed Web of Science ®Google Scholar
• Roy, N., Deveraux, Q. L., Takahashi, R., Salvesen, G. S., and Reed, J. C.. 1997. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16:6914–6925
   PubMed Web of Science ®Google Scholar
• Rutjes, S. A., Utz, P. J., der Heijden, A., Broekhuis, C., van Venrooij, W. J., and Pruijn, G. J.. 1999. The La (SS-B) autoantigen, a key protein in RNA biogenesis, is dephosphorylated and cleaved early during apoptosis. Cell Death Differ. 6:976–986
   PubMedGoogle Scholar
• Sachs, A. B., Sarnow, P., and Hentze, M. W.. 1997. Starting at the beginning, middle, and end: translation initiation in eukaryotes. Cell 89:831–838
   PubMed Web of Science ®Google Scholar
• Seed, B., and Sheen, J. Y.. 1988. A simple phase-extraction assay for chloramphenicol acetyltransferase activity. Gene 67:271–277
   PubMed Web of Science ®Google Scholar
• Seshagiri, S., and Miller, L. K.. 1997. Baculovirus inhibitors of apoptosis (IAPs) block activation of Sf- caspase-1. Proc. Natl. Acad. Sci. USA 94:13606–13611
   PubMedGoogle Scholar
• Seto, A. G., Zaug, A. J., Sobel, S. G., Wolin, S. L., and Cech, T. R.. 1999. Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle. Nature 401:177–180
   PubMed Web of Science ®Google Scholar
• Shiroki, K., Isoyama, T., Kuge, S., Ishii, T., Ohmi, S., Hata, S., Suzuki, K., Takasaki, Y., and Nomoto, A.. 1999. Intracellular redistribution of truncated La protein produced by poliovirus 3Cpro-mediated cleavage. J. Virol. 73:2193–2200
   PubMed Web of Science ®Google Scholar
• Sonenberg, N.. 1996. mRNA 5′ cap-binding protein eIF4E and control of cell growth Translational control. Hershey, J. W. B., Mathews, M. B., and Sonenberg, N. 245–269 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
   Google Scholar
• Stein, I., Itin, A., Einat, P., Skaliter, R., Grossman, Z., and Keshet, E.. 1998. Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia. Mol. Cell. Biol. 18:3112–3119
   PubMed Web of Science ®Google Scholar
• Stoneley, M., Paulin, F. E., Le Quesne, J. P., Chappell, S. A., and Willis, A. E.. 1998. c-myc 5′ untranslated region contains an internal ribosome entry segment. Oncogene 16:423–428
   PubMed Web of Science ®Google Scholar
• Svitkin, Y. V., Pause, A., and Sonenberg, N.. 1994. La autoantigen alleviates translational repression by the 5′ leader sequence of the human immunodeficiency virus type 1 mRNA. J. Virol. 68:7001–7007
   PubMed Web of Science ®Google Scholar
• Takahashi, R., Deveraux, Q., Tamm, I., Welsh, K., Assa-Munt, N., Salvesen, G. S., and Reed, J. C.. 1998. A single BIR domain of XIAP sufficient for inhibiting caspases. J. Biol. Chem. 273:7787–7790
   PubMed Web of Science ®Google Scholar
• Thomson, A. M., Rogers, J. T., Walker, C. E., Staton, J. M., and Leedman, P. J.. 1999. Optimized RNA gel-shift and UV cross-linking assays for characterization of cytoplasmic RNA-protein interactions. Biotechniques 27:1032–1039, 1042.
   PubMedGoogle Scholar
• Vagner, S., Gensac, M. C., Maret, A., Bayard, F., Amalric, F., Prats, H., and Prats, A. C.. 1995. Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes. Mol. Cell. Biol. 15:35–44
   PubMed Web of Science ®Google Scholar
• van der Velden, A. W., and Thomas, A. A.. 1999. The role of the 5′ untranslated region of an mRNA in translation regulation during development. Int. J. Biochem. Cell Biol. 31:87–106
   PubMed Web of Science ®Google Scholar
• White, E.. 1996. Life, death, and the pursuit of apoptosis. Genes Dev. 10:1–15
   PubMed Web of Science ®Google Scholar
• Xu, D., Bureau, Y., McIntyre, D. C., Nicholson, D. W., Liston, P., Zhu, Y., Fong, W. G., Crocker, S. J., Korneluk, R. G., and Robertson, G. S.. 1999. Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus. J. Neurosci. 19:5026–5033
   PubMed Web of Science ®Google Scholar
• Ye, X., Fong, P., Iizuka, N., Choate, D., and Cavener, D. R.. 1997. Ultrabithorax and Antennapedia 5′ untranslated regions promote developmentally regulated internal translation initiation. Mol. Cell. Biol. 17:1714–1721
   PubMedGoogle Scholar