Type B Histone Acetyltransferase Hat1p Participates in Telomeric Silencing

REFERENCES

• Adams, A., Gottschling, D. E., Kaiser, C. A., and Stearns, T.. 1997. Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
   Google Scholar
• Adams, C. R., and Kamakaka, R. T.. 1999. Chromatin assembly: biochemical identities and genetic redundancy. Curr. Opin. Genet. Dev. 9:185–190
   PubMedGoogle Scholar
• Allfrey, V. G., Faulkner, R. M., and Mirsky, A. E.. 1964. Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proc. Natl. Acad. Sci. USA 51:786–794
   PubMed Web of Science ®Google Scholar
• Aparicio, O. M., Billington, B. L., and Gottschling, D. E.. 1991. Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell 66:1279–1287
   PubMed Web of Science ®Google Scholar
• Baudin, A., Ozier-Kalogeropoulos, O., Denouel, A., Lacroute, F., and Cullin, C.. 1993. A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucleic Acids Res. 21:3329–3330
   PubMed Web of Science ®Google Scholar
• Berben, G., Dumont, J., Gilliquet, V., Bolle, P. A., and Hilger, F.. 1991. The YDp plasmids: a uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae. Yeast 7:475–477
   PubMedGoogle Scholar
• Boeke, J. D., Trueheart, J., Natsoulis, G., and Fink, G. R.. 1987. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154:164–175
   PubMed Web of Science ®Google Scholar
• Brachmann, C. B., Davies, A., Cost, G. J., Caputo, E., Li, J., Hieter, P., and Boeke, J. D.. 1998. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14:115–132
   PubMed Web of Science ®Google Scholar
• Braunstein, M., Rose, A. B., Holmes, S. G., Allis, C. D., and Broach, J. R.. 1993. Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev. 7:592–604
   PubMed Web of Science ®Google Scholar
• Braunstein, M., Sobel, R. E., Allis, C. D., Turner, B. M., and Broach, J. R.. 1996. Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern. Mol. Cell. Biol. 16:4349–4356
   PubMed Web of Science ®Google Scholar
• Brownell, J. E., and Allis, C. D.. 1996. Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr. Opin. Genet. Dev. 6:176–184
   PubMed Web of Science ®Google Scholar
• Brownell, J. E., Zhou, J., Ranalli, T., Kobayashi, R., Edmondson, D. G., Roth, S. Y., and Allis, C. D.. 1996. Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84:843–851
   PubMed Web of Science ®Google Scholar
• Chang, L., Loranger, S. S., Mizzen, C., Ernst, S. G., Allis, C. D., and Annunziato, A. T.. 1997. Histones in transit: cytosolic histone complexes and diacetylation of H4 during nucleosome assembly in human cells. Biochemistry 36:469–480
   PubMedGoogle Scholar
• Chen, H., Lin, R. J., Schiltz, R. L., Chakravarti, D., Nash, A., Nagy, L., Privalsky, M. L., Nakatani, Y., and Evans, R. M.. 1997. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell 90:569–580
   PubMed Web of Science ®Google Scholar
• Chicoine, L. G., Schulman, I. G., Richman, R., Cook, R. G., and Allis, C. D.. 1986. Nonrandom utilization of acetylation sites in histones isolated from Tetrahymena: evidence for functionally distinct H4 acetylation sites. J. Biol. Chem. 261:1071–1076
   PubMed Web of Science ®Google Scholar
• Clarke, A. S., Lowell, J. E., Jacobson, S. J., and Pillus, L.. 1999. Esa1p is an essential histone acetyltransferase required for cell cycle progression. Mol. Cell. Biol. 19:2515–2526
   PubMed Web of Science ®Google Scholar
• Enomoto, S., and Berman, J.. 1998. Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev. 12:219–232
   PubMedGoogle Scholar
• Enomoto, S., McCune-Zierath, P. D., Gerami-Nejad, M., Sanders, M. A., and Berman, J.. 1997. RLF2, a subunit of yeast chromatin assembly factor-I, is required for telomeric chromatin function in vivo. Genes Dev. 11:358–370
   PubMedGoogle Scholar
• Gottschling, D. E., Aparicio, O. M., Billington, B. L., and Zakian, V. A.. 1990. Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63:751–762
   PubMed Web of Science ®Google Scholar
• Grant, P. A., and Berger, S. L.. 1999. Histone acetyltransferase complexes. Semin. Cell Dev. Biol. 10:169–177
   PubMed Web of Science ®Google Scholar
• Grant, P. A., Eberharter, A., John, S., Cook, R. G., Turner, B. M., and Workman, J. L.. 1999. Expanded lysine acetylation specificity of Gcn5 in native complexes. J. Biol. Chem. 274:5895–5900
   PubMed Web of Science ®Google Scholar
• Grunstein, M.. 1998. Yeast heterochromatin: regulation of its assembly and inheritance by histones. Cell 93:325–328
   PubMedGoogle Scholar
• Guthrie, C., and Fink, G. R.. 1991. Guide to yeast genetics and mlecular biology. Academic Press, San Diego, Calif
   Google Scholar
• Hassig, C. A., Fleischer, T. C., Billin, A. N., Schreiber, S. L., and Ayer, D. E.. 1997. Histone deacetylase activity is required for full transcriptional repression by mSin3A. Cell 89:341–347
   PubMed Web of Science ®Google Scholar
• Hecht, A., Laroche, T., Strahl-Bolsinger, S., Gasser, S. M., and Grunstein, M.. 1995. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80:583–592
   PubMed Web of Science ®Google Scholar
• Imhof, A., and Wolffe, A. P.. 1999. Purification and properties of the xenopus hat1 acetyltransferase: association with the 14-3-3 proteins in the oocyte nucleus. Biochemistry 38:13085–13093
   PubMed Web of Science ®Google Scholar
• Johnson, C. A., and Turner, B. M.. 1999. Histone deacetylases: complex transducers of nuclear signals. Semin. Cell Dev. Biol. 10:179–188
   PubMed Web of Science ®Google Scholar
• Johnson, L. M., Kayne, P. S., Kahn, E. S., and Grunstein, M.. 1990. Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 87:6286–6290
   PubMedGoogle Scholar
• Kaufman, P. D., Cohen, J. L., and Osley, M. A.. 1998. Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol. Cell. Biol. 18:4793–4806
   PubMedGoogle Scholar
• Kaufman, P. D., Kobayashi, R., Kessler, N., and Stillman, B.. 1995. The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. Cell 81:1105–1114
   PubMedGoogle Scholar
• Kaufman, P. D., Kobayashi, R., and Stillman, B.. 1997. Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev. 11:345–357
   PubMed Web of Science ®Google Scholar
• Kleff, S., Andrulis, E. D., Anderson, C. W., and Sternglanz, R.. 1995. Identification of a gene encoding a yeast histone H4 acetyltransferase. J. Biol. Chem. 270:24674–24677
   PubMed Web of Science ®Google Scholar
• Kuo, M. H., Brownell, J. E., Sobel, R. E., Ranalli, T. A., Cook, R. G., Edmondson, D. G., Roth, S. Y., and Allis, C. D.. 1996. Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines. Nature 383:269–272
   PubMed Web of Science ®Google Scholar
• Le, S., Davis, C., Konopka, J. B., and Sternglanz, R.. 1997. Two new S-phase-specific genes from Saccharomyces cerevisiae. Yeast 13:1029–1042
   PubMedGoogle Scholar
• Ling, X., Harkness, T. A., Schultz, M. C., Fisher-Adams, G., and Grunstein, M.. 1996. Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene regulation. Genes Dev. 10:686–699
   PubMedGoogle Scholar
• Loo, S., and Rine, J.. 1995. Silencing and heritable domains of gene expression. Annu. Rev. Cell Dev. Biol. 11:519–548
   PubMedGoogle Scholar
• Luger, K., Mader, A. W., Richmond, R. K., Sargent, D. F., and Richmond, T. J.. 1997. Crystal structure of the nucleosome core particle at 2.8 Å resolution. Nature 389:251–260
   PubMed Web of Science ®Google Scholar
• Ma, X. J., Wu, J., Altheim, B. A., Schultz, M. C., and Grunstein, M.. 1998. Deposition-related sites K5/K12 in histone H4 are not required for nucleosome deposition in yeast. Proc. Natl. Acad. Sci. USA 95:6693–6698
   PubMed Web of Science ®Google Scholar
• Mann, R. K., and Grunstein, M.. 1992. Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo. EMBO J. 11:3297–3306
   PubMed Web of Science ®Google Scholar
• Martinez-Balbas, M. A., Tsukiyama, T., Gdula, D., and Wu, C.. 1998. Drosophila NURF-55, a WD repeat protein involved in histone metabolism. Proc. Natl. Acad. Sci. USA 95:132–137
   PubMed Web of Science ®Google Scholar
• Mizzen, C. A., Yang, X. J., Kokubo, T., Brownell, J. E., Bannister, A. J., Owen-Hughes, T., Workman, J., Wang, L., Berger, S. L., Kouzarides, T., Nakatani, Y., and Allis, C. D.. 1996. The TAF(II)250 subunit of TFIID has histone acetyltransferase activity. Cell 87:1261–1270
   PubMed Web of Science ®Google Scholar
• Monson, E. K., de Bruin, D., and Zakian, V. A.. 1997. The yeast Cac1 protein is required for the stable inheritance of transcriptionally repressed chromatin at telomeres. Proc. Natl. Acad. Sci. USA 94:13081–13086
   PubMedGoogle Scholar
• Neuwald, A. F., and Landsman, D.. 1997. GCN5-related histone N-acetyltransferases belong to a diverse superfamily that includes the yeast SPT10 protein. Trends Biochem. Sci. 22:154–155
   PubMed Web of Science ®Google Scholar
• Ogryzko, V. V., Schiltz, R. L., Russanova, V., Howard, B. H., and Nakatani, Y.. 1996. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87:953–959
   PubMed Web of Science ®Google Scholar
• Park, E. C., and Szostak, J. W.. 1990. Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML. Mol. Cell. Biol. 10:4932–4934
   PubMedGoogle Scholar
• Parthun, M. R., Widom, J., and Gottschling, D. E.. 1996. The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism. Cell 87:85–94
   PubMed Web of Science ®Google Scholar
• Qian, Y. W., and Lee, E. Y.. 1995. Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast. J. Biol. Chem. 270:25507–25513
   PubMed Web of Science ®Google Scholar
• Qian, Y. W., Wang, Y. C., Hollingsworth, R. E.Jr., Jones, D., Ling, N., and Lee, E. Y.. 1993. A retinoblastoma-binding protein related to a negative regulator of Ras in yeast. Nature 364:648–652
   PubMed Web of Science ®Google Scholar
• Reifsnyder, C., Lowell, J., Clarke, A., and Pillus, L.. 1996. Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat. Genet. 14:42–49
   PubMed Web of Science ®Google Scholar
• Renauld, H., Aparicio, O. M., Zierath, P. D., Billington, B. L., Chhablani, S. K., and Gottschling, D. E.. 1993. Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. Genes Dev. 7:1133–1145
   PubMed Web of Science ®Google Scholar
• Rine, J., and Herskowitz, I.. 1987. Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116:9–22
   PubMed Web of Science ®Google Scholar
• Ruiz-Carillo, A., Wangh, L. J., and Allfry, V.. 1975. Processing of newly synthesized histone molecules. Science 190:117–128
   PubMedGoogle Scholar
• Ruiz-Garcia, A. B., Sendra, R., Galiana, M., Pamblanco, M., Perez-Ortin, J. E., and Tordera, V.. 1998. HAT1 and HAT2 proteins are components of a yeast nuclear histone acetyltransferase enzyme specific for free histone H4. J. Biol. Chem. 273:12599–12605
   PubMed Web of Science ®Google Scholar
• Schmitt, M. E., Brown, T. A., and Trumpower, B. L.. 1990. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res. 18:3091–3092
   PubMed Web of Science ®Google Scholar
• Shore, D.. 1994. RAP1: a protean regulator in yeast. Trends Genet. 10:408–412
   PubMed Web of Science ®Google Scholar
• Singer, M. S., Kahana, A., Wolf, A. J., Meisinger, L. L., Peterson, S. E., Goggin, C., Mahowald, M., and Gottschling, D. E.. 1998. Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150:613–632
   PubMed Web of Science ®Google Scholar
• Smeal, T., Claus, J., Kennedy, B., Cole, F., and Guarente, L.. 1996. Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae. Cell 84:633–642
   PubMed Web of Science ®Google Scholar
• Smith, E. R., Eisen, A., Gu, W., Sattah, M., Pannuti, A., Zhou, J., Cook, R. G., Lucchesi, J. C., and Allis, C. D.. 1998. ESA1 is a histone acetyltransferase that is essential for growth in yeast. Proc. Natl. Acad. Sci. USA 95:3561–3565
   PubMed Web of Science ®Google Scholar
• Smith, S., and Stillman, B.. 1989. Purification and characterization of CAF-1, a human cell factor required for chromatin assembly during DNA replication in vitro. Cell 58:15–25
   PubMed Web of Science ®Google Scholar
• Sobel, R. E., Cook, R. G., Perry, C. A., Annunziato, A. T., and Allis, C. D.. 1995. Conservation of deposition-related acetylation sites in newly synthesized histones H3 and H4. Proc. Natl. Acad. Sci. USA 92:1237–1241
   PubMed Web of Science ®Google Scholar
• Spencer, T. E., Jenster, G., Burcin, M. M., Allis, C. D., Zhou, J., Mizzen, C. A., McKenna, N. J., Onate, S. A., Tsai, S. Y., Tsai, M. J., and O'Malley, B. W.. 1997. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature 389:194–198
   PubMed Web of Science ®Google Scholar
• Sun, Z. W., and Hampsey, M.. 1999. A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae. Genetics 152:921–932
   PubMedGoogle Scholar
• Taunton, J., Hassig, C. A., and Schreiber, S. L.. 1996. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272:408–411
   PubMed Web of Science ®Google Scholar
• Thompson, J. S., Ling, X., and Grunstein, M.. 1994. Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast. Nature 369:245–247
   PubMedGoogle Scholar
• Tse, C., Georgieva, E. I., Ruiz-Garcia, A. B., Sendra, R., and Hansen, J. C.. 1998. Gcn5p, a transcription-related histone acetyltransferase, acetylates nucleosomes and folded nucleosomal arrays in the absence of other protein subunits. J. Biol. Chem. 273:32388–32392
   PubMed Web of Science ®Google Scholar
• Turner, B. M., Birley, A. J., and Lavender, J.. 1992. Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei. Cell 69:375–384
   PubMed Web of Science ®Google Scholar
• Tyler, J. K., Adams, C. R., Chen, S. R., Kobayashi, R., Kamakaka, R. T., and Kadonaga, J. T.. 1999. The RCAF complex mediates chromatin assembly during DNA replication and repair. Nature 402:555–560
   PubMed Web of Science ®Google Scholar
• van Holde, K. E.. 1989. Chromatin. Springer-Verlag, New York, N.Y
   Google Scholar
• Verreault, A., Kaufman, P. D., Kobayashi, R., and Stillman, B.. 1998. Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase. Curr. Biol. 8:96–108
   PubMed Web of Science ®Google Scholar
• Verreault, A., Kaufman, P. D., Kobayashi, R., and Stillman, B.. 1996. Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. Cell 87:95–104
   PubMed Web of Science ®Google Scholar
• Wittschieben, B. O., Otero, G., de Bizemont, T., Fellows, J., Erdjument-Bromage, H., Ohba, R., Li, Y., Allis, C. D., Tempst, P., and Svejstrup, J. Q.. 1999. A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme. Mol. Cell. 4:123–128
   PubMed Web of Science ®Google Scholar
• Yamamoto, T., and Horikoshi, M.. 1997. Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60. J. Biol. Chem. 272:30595–30598
   PubMed Web of Science ®Google Scholar
• Yang, X. J., Ogryzko, V. V., Nishikawa, J., Howard, B. H., and Nakatani, Y.. 1996. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382:319–324
   PubMed Web of Science ®Google Scholar
• Zhang, Y., Iratni, R., Erdjument-Bromage, H., Tempst, P., and Reinberg, D.. 1997. Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex. Cell 89:357–364
   PubMedGoogle Scholar